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Associate Professor Adam Ewing
Associate Professor

Adam Ewing

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Overview

Background

Dr Ewing leads the Translational Bioinformatics Group at the Mater Research Institute - UQ, located at the Translational Research Institute (TRI). His research interests follow a common theme of developing and applying computational methods to investigate genomic mutation in evolutionary and disease-related processes. Dr Ewing is a key collaborator on an array of projects spanning from basic research into clinical applications of Bioinformatics. In particular, his interests include the genomics and epigenomics of epithelial tumours including those arising in prostate, pancreatic, and breast cancer.

Availability

Associate Professor Adam Ewing is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Pennsylvania

Research interests

  • Computational methods for sequence analysis

  • Epithelial tumours

  • Placental genomics

Works

Search Professor Adam Ewing’s works on UQ eSpace

69 works between 2005 and 2026

61 - 69 of 69 works

2012

Journal Article

Extensive somatic L1 retrotransposition in colorectal tumors

Solyom, Szilvia, Ewing, Adam D., Rahrmann, Eric P., Doucet, Tara, Nelson, Heather H., Burns, Michael B., Harris, Reuben S., Sigmon, David F., Casella, Alex, Erlanger, Bracha, Wheelan, Sarah, Upton, Kyle R., Shukla, Ruchi, Faulkner, Geoffrey J., Largaespada, David A. and Kazazian, Haig H. (2012). Extensive somatic L1 retrotransposition in colorectal tumors. Genome Research, 22 (12), 2328-2338. doi: 10.1101/gr.145235.112

Extensive somatic L1 retrotransposition in colorectal tumors

2012

Journal Article

Pathogenic orphan transduction created by a nonreference LINE-1 retrotransposon

Solyom, Szilvia, Ewing, Adam D., Hancks, Dustin C., Takeshima, Yasuhiro, Awano, Hiroyuki, Matsuo, Masafumi and Kazazian, Haig H., Jr. (2012). Pathogenic orphan transduction created by a nonreference LINE-1 retrotransposon. Human Mutation, 33 (2), 369-371. doi: 10.1002/humu.21663

Pathogenic orphan transduction created by a nonreference LINE-1 retrotransposon

2011

Journal Article

Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans

Ewing, Adam D. and Kazazian, Haig H., Jr. (2011). Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans. Genome Research, 21 (6), 985-990. doi: 10.1101/gr.114777.110

Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans

2010

Journal Article

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes

Ewing, Adam D. and Kazazian, Haig H., Jr. (2010). High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes. Genome Research, 20 (9), 1262-1270. doi: 10.1101/gr.106419.110

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes

2009

Journal Article

Exon-trapping mediated by the human retrotransposon SVA

Hancks, Dustin C., Ewing, Adam D., Chen, Jesse E., Tokunaga, Katsushi and Kazazian, Haig H. (2009). Exon-trapping mediated by the human retrotransposon SVA. Genome Research, 19 (11), 1983-1991. doi: 10.1101/gr.093153.109

Exon-trapping mediated by the human retrotransposon SVA

2009

Journal Article

Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria

Slater, Steven C., Goldman, Barry S., Goodner, Brad, Setubal, Joao C., Farrand, Stephen K., Nester, Eugene W., Burr, Thomas J., Banta, Lois, Dickerman, Allan W., Paulsen, Ian, Otten, Leon, Suen, Garret, Welch, Roy, Almeida, Nalvo F., Arnold, Frank, Burton, Oliver T., Du, Zijin, Ewing, Adam, Godsy, Eric, Heisel, Sara, Houmiel, Kathryn L., Jhaveri, Jinal, Lu, Jing, Miller, Nancy M., Norton, Stacie, Chen, Qiang, Phoolcharoen, Waranyoo, Ohlin, Victoria, Ondrusek, Dan ... Wood, Derek W. (2009). Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria. Journal of Bacteriology, 191 (8), 2501-2511. doi: 10.1128/JB.01779-08

Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria

2009

Journal Article

Track roller and idler design improvement using DFSS

Awad, Mahmoud I., Ewing, Adam, Sedlak, George, Yi, Tong and Shanshal, Yassir (2009). Track roller and idler design improvement using DFSS. International Journal of Six Sigma and Competitive Advantage, 5 (1), 29-41. doi: 10.1504/IJSSCA.2009.024213

Track roller and idler design improvement using DFSS

2006

Journal Article

Living with genome instability: The adaptation of phytoplasmas to diverse environments of their insect and plant hosts

Bai, Xiaodong, Zhang, Jianhua, Ewing, Adam, Miller, Sally A., Radek, Agnes Jancso, Shevchenko, Dmitriy V., Tsukerman, Kiryl, Walunas, Theresa, Lapidus, Alla, Campbell, John W. and Hogenhout, Saskia A. (2006). Living with genome instability: The adaptation of phytoplasmas to diverse environments of their insect and plant hosts. Journal of Bacteriology, 188 (10), 3682-3696. doi: 10.1128/JB.188.10.3682-3696.2006

Living with genome instability: The adaptation of phytoplasmas to diverse environments of their insect and plant hosts

2005

Conference Publication

What we can deduce about metabolism in the moderate halophile Chromohalobacter salexigens from its genomic sequence

Csonka, LN, O'Connor, K, Larimer, F, Richardson, P, Lapidus, A, Ewing, AD, Goodner, BW and Oren, A (2005). What we can deduce about metabolism in the moderate halophile Chromohalobacter salexigens from its genomic sequence. Halophiles 2004 International Symposium, Ljubljana Slovenia, Sep 04-09, 2004. SPRINGER.

What we can deduce about metabolism in the moderate halophile Chromohalobacter salexigens from its genomic sequence

Funding

Current funding

  • 2026 - 2027
    Improving early detection of pancreatic cancer by exploring the faulty methylation of the pre-cancerous tissue
    Early Detection
    Open grant
  • 2026 - 2028
    Mechanisms contributing to placental insufficiency and adverse neonatal outcomes across the birthweight centile continuum
    Open grant
  • 2025 - 2028
    A role for mobile DNA in unexplained female infertility
    NHMRC MRFF Infertility Pregnancy Loss and Menopause
    Open grant
  • 2024 - 2029
    Building mRNA Cancer Vaccines for Australia.
    MRFF - National Critical Infrastructure Initiative
    Open grant

Past funding

  • 2021 - 2024
    Mobile DNA activity in the mammalian primordial germline
    ARC Discovery Projects
    Open grant
  • 2021 - 2024
    Long-read genetic and epigenetic profiling in lung cancer for precision medicine
    Priority-driven Collaborative Cancer Research Scheme
    Open grant
  • 2020 - 2024
    The history of the human genome and the mechanisms of genomic disease
    NHMRC MRFF Investigator Grant
    Open grant
  • 2017 - 2018
    Unlocking the cellular determinants of retrotransposition
    ARC Discovery Projects
    Open grant
  • 2015
    Functional annotation of structural variants in human genetic disease
    UQ Early Career Researcher
    Open grant
  • 2015 - 2018
    The functional impact of new genes acquired through retrotransposition
    ARC Discovery Early Career Researcher Award
    Open grant

Supervision

Availability

Associate Professor Adam Ewing is:
Available for supervision

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Available projects

  • Developing software to support Cancer Genomics

Supervision history

Current supervision

Completed supervision

Media

Enquiries

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communications@uq.edu.au