
Overview
Background
Markus graduated from the Vienna University of Technology in Technical Physics in 1995 and was awarded his Doctorate in 1999 after which he worked as postdoctoral research associate and then Assistant Professor at the Department of Radiodiagnostics, Medical University Vienna (AT). From 2004 he worked as Senior Researcher at the Donders Institute for Brain, Cognition and Behaviour (Radboud University Nijmegen, NL) and at the Erwin L. Hahn Institute for Magnetic Resonance Imaging (University Essen-Duisburg, DE). In 2014 he relocated to the University of Queensland to head the Ultra-high Field Human MR Research program at the Centre for Advanced Imaging and was awarded an ARC Future Fellowship. In 2019 he joined the School of Information Technology and Electrical Engineering as Full Professor Biomedical Engineering working on MR Physics and Medical Imaging. He served as Imaging, Sensing and Biomedical Engineering Discipline lead until 2020 when he took up service roles as Deputy Head of School – Research, Director for the National Imaging Facility – Queensland Node, as well as a member of the ARC College of Experts.
Availability
- Professor Markus Barth is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Science (Advanced), Technical University Vienna
Research interests
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Improving MRI
Markus is investigating how MRI can be improved by using new image contrasts by mapping quantitative tissue parameters and by using increased spatial resolution. For example, very small venous vessels and small bleedings in the brain can be visualised using specific contrasts using the MR phase reflecting magnetic susceptibility (SWI and QSM). This information can be used as a very sensitive disease marker in a range of neurodegenerative diseases (traumatic brain injuries, tumours, dementia). He is also developing faster image acquisition methods such as 3D Echo-Planar-Imaging (EPI) that allows reducing the acquisition time by a factor 5-10 compared to standard techniques while keeping the high image fidelity.
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Understanding brain activity using functional MRI
Blood oxygenation level dependent (BOLD) functional MRI gives a good picture of neural activation and connectivity in the living human brain non-invasively. Markus is particularly interested to identify small functional units of the brain, such as cortical layers and columns, in order to better understand brain function by developing very fast functional MRI techniques with the highest spatial resolution possible. Recently, he also addressed important neuroscientific questions such as memory consolidation during sleep and decoding measured functional signals (brain reading). He also explored the possibilities of simultaneous acquisition of EEG and fMRI to examine the link between electrophysiology and BOLD task activity and large scale brain networks.
Research impacts
Markus has made significant scientific contributions in the fields of Cognitive Neuroscience, Neuroimaging, and MR methods at (ultra-)high field and key contributions to MRI scanner software packages, which are used in MR labs worldwide. Markus’ main interest is to improve our understanding of brain function and disfunction in cognition, neurodegenerative diseases, and cancer by developing new medical imaging techniques. With a focus on human neuroimaging using magnetic resonance imaging (MRI) at high and ultra-high magnetic field strength, he achieved fast, high resolution mapping of magnetic susceptibility related anatomical and functional information in vivo, including characterisation of blood oxygenation, iron storage in tissue, haemorrhage and calcifications. Recent achievements include the development of accurate detection of layer specific functional activation in the human brain, decoding of brain activity and ultra-fast MRI. His research interests are in the fields of MR method development including applications in neuroimaging and neurological diseases including dementia, motor neurone disease, and cancer.
Works
Search Professor Markus Barth’s works on UQ eSpace
2020
Journal Article
Influence of 7T GRE-MRI signal compartment model choice on tissue parameters
Thapaliya, Kiran, Vegh, Viktor, Bollmann, Steffen and Barth, Markus (2020). Influence of 7T GRE-MRI signal compartment model choice on tissue parameters. Frontiers in Neuroscience, 14 271, 271. doi: 10.3389/fnins.2020.00271
2020
Journal Article
Bayesian population receptive field modeling in human somatosensory cortex
Puckett, Alexander M., Bollmann, Saskia, Junday, Keerat, Barth, Markus and Cunnington, Ross (2020). Bayesian population receptive field modeling in human somatosensory cortex. NeuroImage, 208 116465, 116465. doi: 10.1016/j.neuroimage.2019.116465
2019
Journal Article
Non-linear realignment improves hippocampus subfield segmentation reliability
Shaw, Thomas B., Bollmann, Steffen, Atcheson, Nicole T., Strike, Lachlan T., Guo, Christine, McMahon, Katie L., Fripp, Jurgen, Wright, Margaret J., Salvado, Olivier and Barth, Markus (2019). Non-linear realignment improves hippocampus subfield segmentation reliability. NeuroImage, 203 116206, 116206. doi: 10.1016/j.neuroimage.2019.116206
2019
Journal Article
7T GRE-MRI signal compartments are sensitive to dysplastic tissue in focal epilepsy
Thapaliya, Kiran, Urriola, Javier, Barth, Markus, Reutens, David C., Bollmann, Steffen and Vegh, Viktor (2019). 7T GRE-MRI signal compartments are sensitive to dysplastic tissue in focal epilepsy. Magnetic Resonance Imaging, 61, 1-8. doi: 10.1016/j.mri.2019.05.011
2019
Journal Article
DeepQSM - using deep learning to solve the dipole inversion for quantitative susceptibility mapping
Bollmann, Steffen, Rasmussen, Kasper Gade Bøtker, Kristensen, Mads, Blendal, Rasmus Guldhammer, Østergaard, Lasse Riis, Plocharski, Maciej, O'Brien, Kieran, Langkammer, Christian, Janke, Andrew and Barth, Markus (2019). DeepQSM - using deep learning to solve the dipole inversion for quantitative susceptibility mapping. NeuroImage, 195, 373-383. doi: 10.1016/j.neuroimage.2019.03.060
2019
Journal Article
A numerical and experimental study of RF shimming in the presence of hip prostheses using adaptive SAR at 3 T
Destruel, Aurelien, Fuentes, Miguel, Weber, Ewald, O'Brien, Kieran, Jin, Jin, Liu, Feng, Barth, Markus and Crozier, Stuart (2019). A numerical and experimental study of RF shimming in the presence of hip prostheses using adaptive SAR at 3 T. Magnetic Resonance in Medicine, 81 (6), 3826-3839. doi: 10.1002/mrm.27688
2019
Journal Article
SHARQnet – Sophisticated harmonic artifact reduction in quantitative susceptibility mapping using a deep convolutional neural network
Bollmann, Steffen, Kristensen, Matilde Holm, Larsen, Morten Skaarup, Olsen, Mathias Vassard, Pedersen, Mads Jozwiak, Østergaard, Lasse Riis, O’Brien, Kieran, Langkammer, Christian, Fazlollahi, Amir and Barth, Markus (2019). SHARQnet – Sophisticated harmonic artifact reduction in quantitative susceptibility mapping using a deep convolutional neural network. Zeitschrift für Medizinische Physik, 29 (2), 139-149. doi: 10.1016/j.zemedi.2019.01.001
2019
Journal Article
Cardiac magnetic resonance imaging at 7 Tesla
Stäb, Daniel, Al Najjar, Aiman, O'Brien, Kieran, Strugnell, Wendy, Richer, Jonathan, Rieger, Jan, Niendorf, Thoralf and Barth, Markus (2019). Cardiac magnetic resonance imaging at 7 Tesla. Journal of Visualized Experiments, 2019 (143) e55853. doi: 10.3791/55853
2019
Conference Publication
7-Tesla Cardiac MRI with vector-ECG gating despite the magnetohydrodynamic effect in healthy volunteers
Hamilton-Craig, C., Staeb, D., O'Brien, K., Galloway, G. and Barth, M. (2019). 7-Tesla Cardiac MRI with vector-ECG gating despite the magnetohydrodynamic effect in healthy volunteers. EuroCMR 2019, Venice, Italy, 2-4 May 2019. Oxford, United Kingdom: Oxford University Press.
2019
Journal Article
Adaptive SAR mass-averaging framework to improve predictions of local RF heating near a hip implant for parallel transmit at 7 T
Destruel, Aurelien, O'Brien, Kieran, Jin, Jin, Liu, Feng, Barth, Markus and Crozier, Stuart (2019). Adaptive SAR mass-averaging framework to improve predictions of local RF heating near a hip implant for parallel transmit at 7 T. Magnetic Resonance in Medicine, 81 (1), 615-627. doi: 10.1002/mrm.27379
2018
Journal Article
Cued reactivation during slow-wave sleep induces brain connectivity changes related to memory stabilization
Berkers, Ruud M. W. J., Ekman, Matthias, van Dongen, Eelco. V., Takashima, Atsuko, Barth, Markus, Paller, Ken. A. and Fernández, Guillén (2018). Cued reactivation during slow-wave sleep induces brain connectivity changes related to memory stabilization. Scientific Reports, 8 (1) 16958, 16958. doi: 10.1038/s41598-018-35287-6
2018
Journal Article
PEC-GRAPPA reconstruction of simultaneous multislice EPI with slice-dependent 2D Nyquist ghost correction
Liu, Yilong, Lyu, Mengye, Barth, Markus, Yi, Zheyuan, Leong, Alex T. L., Chen, Fei, Feng, Yanqiu and Wu, Ed X. (2018). PEC-GRAPPA reconstruction of simultaneous multislice EPI with slice-dependent 2D Nyquist ghost correction. Magnetic Resonance in Medicine, 81 (3), 1924-1934. doi: 10.1002/mrm.27546
2018
Journal Article
Robust SENSE reconstruction of simultaneous multislice EPI with low-rank enhanced coil sensitivity calibration and slice-dependent 2D Nyquist ghost correction
Lyu, Mengye, Barth, Markus, Xie, Victor B., Liu, Yilong, Ma, Xin, Feng, Yanqiu and Wu, Ed X. (2018). Robust SENSE reconstruction of simultaneous multislice EPI with low-rank enhanced coil sensitivity calibration and slice-dependent 2D Nyquist ghost correction. Magnetic Resonance in Medicine, 80 (4), 1376-1390. doi: 10.1002/mrm.27120
2018
Conference Publication
Improving FLAIR SAR efficiency by predicting B1-maps at 7T from a standard localizer scan using deep convolutional neural networks
Bollmann, Steffen, Kelly, Samuel, Vegh, Viktor, Rodell, Anders, Tesiram, Yas, Barth, Markus and O'Brien, Kieran (2018). Improving FLAIR SAR efficiency by predicting B1-maps at 7T from a standard localizer scan using deep convolutional neural networks. ISMRM, Paris, France, 17-21 June 2018.
2018
Conference Publication
7-Tesla Cardiac MRI for ventricular and valvular quantitation in healthy volunteers
Hamilton-Craig, C., Staeb, D., O'Brien, K., Galloway, G. and Barth, M. (2018). 7-Tesla Cardiac MRI for ventricular and valvular quantitation in healthy volunteers. European Society of Cardiology Congress (ESCC 2018), Munich, Germany, 25-29 August 2018. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/eurheartj/ehy565.1163
2018
Conference Publication
Myelin water fraction across the corpus callosum using multi-echo gradient echo at 7T - influence of model settings and flip angle
Thapaliya, Kiran, Vegh, Viktor, Bollmann, Steffen and Barth, Markus (2018). Myelin water fraction across the corpus callosum using multi-echo gradient echo at 7T - influence of model settings and flip angle. ISMRM, Paris, France, 16-21 June 2018.
2018
Conference Publication
Echo time dependence in temporal frequency shift curves at 3T and 7T
Sood, Surabhi, Reutens, David, Kadamangudi, Shrinath, Barth, Markus and Vegh, Viktor (2018). Echo time dependence in temporal frequency shift curves at 3T and 7T. ISMRM, Paris, France, 16-21 June 2018.
2018
Conference Publication
7T GRE-MRI frequency shifts obtained from signal compartments can differentiate normal from dysplastic tissue in focal epilepsy
Thapaliya, Kiran, Barth, Markus, Bollmann, Steffen, Reutens, David and Vegh, Viktor (2018). 7T GRE-MRI frequency shifts obtained from signal compartments can differentiate normal from dysplastic tissue in focal epilepsy. ISMRM, Paris, France, 16-21 June 2018.
2018
Journal Article
Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction
McCombe, Pamela A., Ngo, Shyuan T., Guo, Christine Cong, Fazlollahi, Amir, Bollmann, Saskia, Wang, Liting, Hu, Xintao, Barth, Markus, Salvado, Olivier, Davis, Mark, Ceslis, Amelia, Robinson, Gail, Henderson, Robert D. and Steyn, Frederik J. (2018). Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction. Journal of Neurology, Neurosurgery and Psychiatry, 90 (8), 952-954. doi: 10.1136/jnnp-2018-318823
2017
Journal Article
Using multi-echo simultaneous multi-slice (SMS) EPI to improve functional MRI of the subcortical nuclei of the basal ganglia at ultra-high field (7T)
Puckett, Alexander M., Bollmann, Saskia, Poser, Benedikt A., Palmer, Jake, Barth, Markus and Cunnington, Ross (2017). Using multi-echo simultaneous multi-slice (SMS) EPI to improve functional MRI of the subcortical nuclei of the basal ganglia at ultra-high field (7T). NeuroImage, 172, 886-895. doi: 10.1016/j.neuroimage.2017.12.005
Funding
Current funding
Supervision
Availability
- Professor Markus Barth is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Magnetic Resonance Spectroscopy in Patients with Motor Neuron Disease at 3T and 7T
Principal Advisor
Other advisors: Dr Thomas Shaw
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Doctor Philosophy
Neural Network¿Enhanced Multimodal Brain Electrical Source Imaging and Applications
Principal Advisor
Other advisors: Dr Steffen Bollmann
-
Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
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Doctor Philosophy
Validation of Quantitative Susceptibility Mapping (QSM) in Magnetic Resonance Imaging
Principal Advisor
Other advisors: Dr Monique Tourell
-
Doctor Philosophy
Development of a deep learning framework for multi-modal medical imaging
Principal Advisor
Other advisors: Dr Steffen Bollmann
-
Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
-
Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
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Doctor Philosophy
Improving vascular MRI with deep learning.
Associate Advisor
Other advisors: Dr Fernanda Lenita Ribeiro, Dr Saskia Bollmann
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Doctor Philosophy
Additive manufacturing in the patient specific optimisation of intracavitary brachytherapy
Associate Advisor
Other advisors: Dr Scott Crowe
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Doctor Philosophy
Additive manufacturing in the patient specific optimisation of intracavitary brachytherapy
Associate Advisor
Other advisors: Dr Scott Crowe
-
Doctor Philosophy
Parallel Transmission for Advanced MRI Techniques at Ultra-High Field
Associate Advisor
Completed supervision
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2023
Doctor Philosophy
Improving functional MRI through Modelling and Imaging Microvascular Dynamics
Principal Advisor
Other advisors: Dr Saskia Bollmann, Associate Professor Kai-Hsiang Chuang
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2022
Doctor Philosophy
Modelling the Depth-dependent Functional Responses in Human Primary Visual and Motor Cortices
Principal Advisor
Other advisors: Dr Saskia Bollmann
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2021
Doctor Philosophy
Sequence Development to Improve Image Quality for T2- and Diffusion Weighted Imaging at 7T
Principal Advisor
Other advisors: Dr Steffen Bollmann
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2020
Doctor Philosophy
MR signal modelling approaches to characterise tissue microstructure in in-vivo human brain
Principal Advisor
Other advisors: Dr Steffen Bollmann
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2018
Doctor Philosophy
Evaluating Acquisition Techniques for Functional Magnetic Resonance Imaging at Ultra-High Field
Principal Advisor
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2019
Doctor Philosophy
Radiofrequency safety and shimming near metal hip prostheses at high and ultra-high field MRI
Joint Principal Advisor
Other advisors: Professor Feng Liu, Emeritus Professor Stuart Crozier
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2024
Doctor Philosophy
Efficient Image Representations for Compressed Sensing MRI
Associate Advisor
Other advisors: Associate Professor Craig Engstrom, Professor Feng Liu, Dr Shakes Chandra
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2024
Doctor Philosophy
Parallel Transmission for Advanced MRI Techniques at Ultra-High Field
Associate Advisor
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2023
Master Philosophy
Solving Quantitative Susceptibility Mapping using Deep Learning
Associate Advisor
Other advisors: Dr Steffen Bollmann
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2023
Doctor Philosophy
Automated Quantitative Susceptibility Mapping for Clinical Applications
Associate Advisor
Other advisors: Dr Monique Tourell, Dr Steffen Bollmann
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2021
Doctor Philosophy
Computational in vivo Tissue Characterisation for Multi-Contrast High-Resolution Magnetic Resonance Imaging Data
Associate Advisor
Other advisors: Dr Steffen Bollmann
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2019
Doctor Philosophy
Measuring tissue variations in the human brain using quantitative MRI
Associate Advisor
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2018
Doctor Philosophy
Neural correlates of visual function in agenesis of the corpus callosum
Associate Advisor
Other advisors: Professor Jason Mattingley
Media
Enquiries
Contact Professor Markus Barth directly for media enquiries about:
- Biomedical engineering
- Biomedical Imaging
- Brain imaging
- Diffusion imaging
- fMRI
- Image analysis
- Image reconstruction
- Imaging Processing
- Magnetic Resonance Imaging
- MR Imaging Techniques
- MRI
- Neuroimaging
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