
Overview
Background
Markus graduated from the Vienna University of Technology in Technical Physics in 1995 and was awarded his Doctorate in 1999 after which he worked as postdoctoral research associate and then Assistant Professor at the Department of Radiodiagnostics, Medical University Vienna (AT). From 2004 he worked as Senior Researcher at the Donders Institute for Brain, Cognition and Behaviour (Radboud University Nijmegen, NL) and at the Erwin L. Hahn Institute for Magnetic Resonance Imaging (University Essen-Duisburg, DE). In 2014 he relocated to the University of Queensland to head the Ultra-high Field Human MR Research program at the Centre for Advanced Imaging and was awarded an ARC Future Fellowship. In 2019 he joined the School of Information Technology and Electrical Engineering as Full Professor Biomedical Engineering working on MR Physics and Medical Imaging. He served as Imaging, Sensing and Biomedical Engineering Discipline lead until 2020 when he took up service roles as Deputy Head of School – Research, Director for the National Imaging Facility – Queensland Node, as well as a member of the ARC College of Experts.
Availability
- Professor Markus Barth is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Science (Advanced), Technical University Vienna
Research interests
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Improving MRI
Markus is investigating how MRI can be improved by using new image contrasts by mapping quantitative tissue parameters and by using increased spatial resolution. For example, very small venous vessels and small bleedings in the brain can be visualised using specific contrasts using the MR phase reflecting magnetic susceptibility (SWI and QSM). This information can be used as a very sensitive disease marker in a range of neurodegenerative diseases (traumatic brain injuries, tumours, dementia). He is also developing faster image acquisition methods such as 3D Echo-Planar-Imaging (EPI) that allows reducing the acquisition time by a factor 5-10 compared to standard techniques while keeping the high image fidelity.
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Understanding brain activity using functional MRI
Blood oxygenation level dependent (BOLD) functional MRI gives a good picture of neural activation and connectivity in the living human brain non-invasively. Markus is particularly interested to identify small functional units of the brain, such as cortical layers and columns, in order to better understand brain function by developing very fast functional MRI techniques with the highest spatial resolution possible. Recently, he also addressed important neuroscientific questions such as memory consolidation during sleep and decoding measured functional signals (brain reading). He also explored the possibilities of simultaneous acquisition of EEG and fMRI to examine the link between electrophysiology and BOLD task activity and large scale brain networks.
Research impacts
Markus has made significant scientific contributions in the fields of Cognitive Neuroscience, Neuroimaging, and MR methods at (ultra-)high field and key contributions to MRI scanner software packages, which are used in MR labs worldwide. Markus’ main interest is to improve our understanding of brain function and disfunction in cognition, neurodegenerative diseases, and cancer by developing new medical imaging techniques. With a focus on human neuroimaging using magnetic resonance imaging (MRI) at high and ultra-high magnetic field strength, he achieved fast, high resolution mapping of magnetic susceptibility related anatomical and functional information in vivo, including characterisation of blood oxygenation, iron storage in tissue, haemorrhage and calcifications. Recent achievements include the development of accurate detection of layer specific functional activation in the human brain, decoding of brain activity and ultra-fast MRI. His research interests are in the fields of MR method development including applications in neuroimaging and neurological diseases including dementia, motor neurone disease, and cancer.
Works
Search Professor Markus Barth’s works on UQ eSpace
2022
Conference Publication
Investigating the computational reproducibility of Neurodesk
Dao, Thuy, Renton, Angela, Narayanan, Aswin, Barth, Markus and Bollmann, Steffen (2022). Investigating the computational reproducibility of Neurodesk. International Society for Magnetic Resonance in Medicine ANZ Chapter, Sydney, NSW, Australia, 12-13 November 2022.
2022
Journal Article
Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS
Chang, Jeryn, Shaw, Thomas B., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Fripp, Jurgen, Barth, Markus, Guo, Christine C., Ngo, Shyuan T. and Steyn, Frederik J. (2022). Lower hypothalamic volume with lower BMI is associated with shorter survival in patients with ALS. European Journal of Neurology, 30 (1), 57-68. doi: 10.1111/ene.15589
2022
Journal Article
Modelling the depth‐dependent VASO and BOLD responses in human primary visual cortex
Akbari, Atena, Bollmann, Saskia, Ali, Tonima S. and Barth, Markus (2022). Modelling the depth‐dependent VASO and BOLD responses in human primary visual cortex. Human Brain Mapping, 44 (2), 710-726. doi: 10.1002/hbm.26094
2022
Journal Article
Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T
Chang, Jeryn, Steyn, Frederik, Ngo, Shyuan, Henderson, Robert, Guo, Christine, Bollmann, Steffen, Fripp, Jurgen, Barth, Markus and Shaw, Thomas (2022). Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T. Journal of Open Source Software, 7 (76), 4368. doi: 10.21105/joss.04368
2022
Conference Publication
Quantitative susceptibility mapping as an alternative to CT for localizing gold intraprostatic fiducial markers
Stewart, Ashley Wilton, Goodwin, Jonathan, Robinson, Simon Daniel, O’Brien, Kieran, Jin, Jin, Barth, Markus and Bollmann, Stefan (2022). Quantitative susceptibility mapping as an alternative to CT for localizing gold intraprostatic fiducial markers. ISMRM 2022, London, United Kingdom, 7-12 May 2022. Concord, CA USA: International Society for Magnetic Resonance in Medicine.
2021
Journal Article
New acquisition techniques and their prospects for the achievable resolution of fMRI
Bollmann, Saskia and Barth, Markus (2021). New acquisition techniques and their prospects for the achievable resolution of fMRI. Progress in Neurobiology, 207 101936, 1-15. doi: 10.1016/j.pneurobio.2020.101936
2021
Conference Publication
QSMxT: a fully automated, quantitative susceptibility mapping pipeline
Stewart, Ashley, Robinson, Simon Daniel, O’Brien, Kieran, Jin, Jin, Walls, Angela, Narayanan, Aswin, Barth, Markus and Bollman, Steffen (2021). QSMxT: a fully automated, quantitative susceptibility mapping pipeline. AusIron 2021, Brisbane, QLD Australia, 29 November 2021. Brisbane, QLD Australia: QIMR Berghofer Medical Research Institute.
2021
Conference Publication
QSM as an alternative to CT for localizing gold intraprostatic fiducial markers
Wilton Stewart, Ashley, Goodwin, Jonathan, Robinson, Simon Daniel, O’Brien, Kieran, Jin, Jin, Barth, Markus and Bollmann, Steffen (2021). QSM as an alternative to CT for localizing gold intraprostatic fiducial markers. 3rd Annual Meeting of the ISMRM ANZ Chapter, 2021, Online, 22-23 November 2021. International Society for Magnetic Resonance in Medicine ANZ Chapter.
2021
Conference Publication
QSMxT:a fully automated, quantitative susceptibility mapping pipeline
Stewart, Ashley Wilton, Robinson, Simon Daniel, O’Brien, Kieran, Jin, Jin, Walls, Angela, Narayanan, Aswin, Barth, Markus and Bollmann, Steffen (2021). QSMxT:a fully automated, quantitative susceptibility mapping pipeline. 3rd Annual Meeting of the ISMRM ANZ Chapter, 2021, Online, 22-23 November. International Society for Magnetic Resonance in Medicine ANZ Chapter.
2021
Journal Article
QSMxT: Robust masking and artifact reduction for quantitative susceptibility mapping
Stewart, Ashley Wilton, Robinson, Simon Daniel, O’Brien, Kieran, Jin, Jin, Widhalm, Georg, Hangel, Gilbert, Walls, Angela, Goodwin, Jonathan, Eckstein, Korbinian, Tourell, Monique, Morgan, Catherine, Narayanan, Aswin, Barth, Markus and Bollmann, Steffen (2021). QSMxT: Robust masking and artifact reduction for quantitative susceptibility mapping. Magnetic Resonance in Medicine, 87 (3), 1289-1300. doi: 10.1002/mrm.29048
2021
Journal Article
Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
Cohen-Adad, Julien, Alonso-Ortiz, Eva, Abramovic, Mihael, Arneitz, Carina, Atcheson, Nicole, Barlow, Laura, Barry, Robert L., Barth, Markus, Battiston, Marco, Büchel, Christian, Budde, Matthew, Callot, Virginie, Combes, Anna J. E., De Leener, Benjamin, Descoteaux, Maxime, de Sousa, Paulo Loureiro, Dostál, Marek, Doyon, Julien, Dvorak, Adam, Eippert, Falk, Epperson, Karla R., Epperson, Kevin S., Freund, Patrick, Finsterbusch, Jürgen, Foias, Alexandru, Fratini, Michela, Fukunaga, Issei, Gandini Wheeler-Kingshott, Claudia A. M., Germani, Giancarlo ... Xu, Junqian (2021). Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Scientific Data, 8 (1) 251, 251. doi: 10.1038/s41597-021-01044-0
2021
Journal Article
Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
Cohen-Adad, Julien, Alonso-Ortiz, Eva, Abramovic, Mihael, Arneitz, Carina, Atcheson, Nicole, Barlow, Laura, Barry, Robert L., Barth, Markus, Battiston, Marco, Büchel, Christian, Budde, Matthew, Callot, Virginie, Combes, Anna J. E., De Leener, Benjamin, Descoteaux, Maxime, de Sousa, Paulo Loureiro, Dostál, Marek, Doyon, Julien, Dvorak, Adam, Eippert, Falk, Epperson, Karla R., Epperson, Kevin S., Freund, Patrick, Finsterbusch, Jürgen, Foias, Alexandru, Fratini, Michela, Fukunaga, Issei, Gandini Wheeler-Kingshott, Claudia A. M., Germani, Giancarlo ... Xu, Junqian (2021). Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Scientific Data, 8 (1) 242, 242. doi: 10.1038/s41597-021-01026-2
2021
Journal Article
Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
Cohen-Adad, Julien, Alonso-Ortiz, Eva, Abramovic, Mihael, Arneitz, Carina, Atcheson, Nicole, Barlow, Laura, Barry, Robert L., Barth, Markus, Battiston, Marco, Büchel, Christian, Budde, Matthew, Callot, Virginie, Combes, Anna J. E., De Leener, Benjamin, Descoteaux, Maxime, de Sousa, Paulo Loureiro, Dostál, Marek, Doyon, Julien, Dvorak, Adam, Eippert, Falk, Epperson, Karla R., Epperson, Kevin S., Freund, Patrick, Finsterbusch, Jürgen, Foias, Alexandru, Fratini, Michela, Fukunaga, Issei, Gandini Wheeler-Kingshott, Claudia A. M., Germani, Giancarlo ... Xu, Junqian (2021). Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Scientific Data, 8 (1) 219, 1-17. doi: 10.1038/s41597-021-00941-8
2021
Journal Article
Generic acquisition protocol for quantitative MRI of the spinal cord
Cohen-Adad, Julien, Alonso-Ortiz, Eva, Abramovic, Mihael, Arneitz, Carina, Atcheson, Nicole, Barlow, Laura, Barry, Robert L., Barth, Markus, Battiston, Marco, Büchel, Christian, Budde, Matthew, Callot, Virginie, Combes, Anna J. E., De Leener, Benjamin, Descoteaux, Maxime, de Sousa, Paulo Loureiro, Dostál, Marek, Doyon, Julien, Dvorak, Adam, Eippert, Falk, Epperson, Karla R., Epperson, Kevin S., Freund, Patrick, Finsterbusch, Jürgen, Foias, Alexandru, Fratini, Michela, Fukunaga, Issei, Wheeler-Kingshott, Claudia A. M. Gandini, Germani, Giancarlo ... Xu, Junqian (2021). Generic acquisition protocol for quantitative MRI of the spinal cord. Nature Protocols, 16 (10), 4611-4632. doi: 10.1038/s41596-021-00588-0
2021
Journal Article
Improved susceptibility weighted imaging at ultra-high field using bipolar multi-echo acquisition and optimized image processing: CLEAR-SWI
Eckstein, Korbinian, Bachrata, Beata, Hangel, Gilbert, Widhalm, Georg, Enzinger, Christian, Barth, Markus, Trattnig, Siegfried and Robinson, Simon Daniel (2021). Improved susceptibility weighted imaging at ultra-high field using bipolar multi-echo acquisition and optimized image processing: CLEAR-SWI. NeuroImage, 237 118175, 1-17. doi: 10.1016/j.neuroimage.2021.118175
2021
Journal Article
7-tesla functional cardiovascular MR using vectorcardiographic triggering—overcoming the magnetohydrodynamic effect
Hamilton-Craig, Christian, Stäeb, Daniel, Al Najjar, Aiman, O’Brien, Kieran, Crawford, William, Fletcher, Sabine, Barth, Markus and Galloway, Graham (2021). 7-tesla functional cardiovascular MR using vectorcardiographic triggering—overcoming the magnetohydrodynamic effect. Tomography, 7 (3), 323-332. doi: 10.3390/tomography7030029
2021
Journal Article
Improving FLAIR SAR efficiency at 7T by adaptive tailoring of adiabatic pulse power through deep learning estimation
Abbasi‐Rad, Shahrokh, O’Brien, Kieran, Kelly, Samuel, Vegh, Viktor, Rodell, Anders, Tesiram, Yasvir, Jin, Jin, Barth, Markus and Bollmann, Steffen (2021). Improving FLAIR SAR efficiency at 7T by adaptive tailoring of adiabatic pulse power through deep learning estimation. Magnetic Resonance in Medicine, 85 (5), 2462-2476. doi: 10.1002/mrm.28590
2020
Journal Article
Longitudinal Automatic Segmentation of Hippocampal Subfields (LASHiS) using multi-contrast MRI
Shaw, Thomas, York, Ashley, Ziaei, Maryam, Barth, Markus and Bollmann, Steffen (2020). Longitudinal Automatic Segmentation of Hippocampal Subfields (LASHiS) using multi-contrast MRI. NeuroImage, 218 116798, 116798. doi: 10.1016/j.neuroimage.2020.116798
2020
Journal Article
Towards optimising MRI characterisation of Tissue (TOMCAT) dataset including all Longitudinal Automatic Segmentation of Hippocampal Subfields (LASHiS) data
Shaw, Thomas, York, Ashley, Barth, Markus and Bollmann, Steffen (2020). Towards optimising MRI characterisation of Tissue (TOMCAT) dataset including all Longitudinal Automatic Segmentation of Hippocampal Subfields (LASHiS) data. Data in Brief, 32 106043, 106043. doi: 10.1016/j.dib.2020.106043
2020
Journal Article
Field strength influences on gradient recalled echo MRI signal compartment frequency shifts
Sood, Surabhi, Reutens, David C., Kadamangudi, Shrinath, Barth, Markus and Vegh, Viktor (2020). Field strength influences on gradient recalled echo MRI signal compartment frequency shifts. Magnetic Resonance Imaging, 70, 98-107. doi: 10.1016/j.mri.2020.04.018
Funding
Current funding
Supervision
Availability
- Professor Markus Barth is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
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Doctor Philosophy
Magnetic Resonance Spectroscopy in Patients with Motor Neuron Disease at 3T and 7T
Principal Advisor
Other advisors: Dr Thomas Shaw
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Doctor Philosophy
Neural Network¿Enhanced Multimodal Brain Electrical Source Imaging and Applications
Principal Advisor
Other advisors: Dr Steffen Bollmann
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Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
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Doctor Philosophy
Validation of Quantitative Susceptibility Mapping (QSM) in Magnetic Resonance Imaging
Principal Advisor
Other advisors: Dr Monique Tourell
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Doctor Philosophy
Development of a deep learning framework for multi-modal medical imaging
Principal Advisor
Other advisors: Dr Steffen Bollmann
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Doctor Philosophy
Development of a framework for quality assurance and quality control for magnetic resonance and molecular imaging modalities
Principal Advisor
Other advisors: Dr Monique Tourell
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Doctor Philosophy
Additive manufacturing in the patient specific optimisation of intracavitary brachytherapy
Associate Advisor
Other advisors: Dr Scott Crowe
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Doctor Philosophy
Additive manufacturing in the patient specific optimisation of intracavitary brachytherapy
Associate Advisor
Other advisors: Dr Scott Crowe
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Doctor Philosophy
Parallel Transmission for Advanced MRI Techniques at Ultra-High Field
Associate Advisor
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Doctor Philosophy
Improving vascular MRI with deep learning.
Associate Advisor
Other advisors: Dr Fernanda Lenita Ribeiro, Dr Saskia Bollmann
Completed supervision
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2023
Doctor Philosophy
Improving functional MRI through Modelling and Imaging Microvascular Dynamics
Principal Advisor
Other advisors: Dr Saskia Bollmann, Associate Professor Kai-Hsiang Chuang
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2022
Doctor Philosophy
Modelling the Depth-dependent Functional Responses in Human Primary Visual and Motor Cortices
Principal Advisor
Other advisors: Dr Saskia Bollmann
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2021
Doctor Philosophy
Sequence Development to Improve Image Quality for T2- and Diffusion Weighted Imaging at 7T
Principal Advisor
Other advisors: Dr Steffen Bollmann
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2020
Doctor Philosophy
MR signal modelling approaches to characterise tissue microstructure in in-vivo human brain
Principal Advisor
Other advisors: Dr Steffen Bollmann
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2018
Doctor Philosophy
Evaluating Acquisition Techniques for Functional Magnetic Resonance Imaging at Ultra-High Field
Principal Advisor
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2019
Doctor Philosophy
Radiofrequency safety and shimming near metal hip prostheses at high and ultra-high field MRI
Joint Principal Advisor
Other advisors: Professor Feng Liu, Emeritus Professor Stuart Crozier
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2024
Doctor Philosophy
Efficient Image Representations for Compressed Sensing MRI
Associate Advisor
Other advisors: Associate Professor Craig Engstrom, Professor Feng Liu, Dr Shakes Chandra
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2024
Doctor Philosophy
Parallel Transmission for Advanced MRI Techniques at Ultra-High Field
Associate Advisor
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2023
Doctor Philosophy
Automated Quantitative Susceptibility Mapping for Clinical Applications
Associate Advisor
Other advisors: Dr Monique Tourell, Dr Steffen Bollmann
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2023
Master Philosophy
Solving Quantitative Susceptibility Mapping using Deep Learning
Associate Advisor
Other advisors: Dr Steffen Bollmann
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2021
Doctor Philosophy
Computational in vivo Tissue Characterisation for Multi-Contrast High-Resolution Magnetic Resonance Imaging Data
Associate Advisor
Other advisors: Dr Steffen Bollmann
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2019
Doctor Philosophy
Measuring tissue variations in the human brain using quantitative MRI
Associate Advisor
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2018
Doctor Philosophy
Neural correlates of visual function in agenesis of the corpus callosum
Associate Advisor
Other advisors: Professor Jason Mattingley
Media
Enquiries
Contact Professor Markus Barth directly for media enquiries about:
- Biomedical engineering
- Biomedical Imaging
- Brain imaging
- Diffusion imaging
- fMRI
- Image analysis
- Image reconstruction
- Imaging Processing
- Magnetic Resonance Imaging
- MR Imaging Techniques
- MRI
- Neuroimaging
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