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2018 Book Chapter Trends in cyclotide researchKan, Meng-Wei and Craik, David J. (2018). Trends in cyclotide research. Cyclic peptides: from bioorganic synthesis to applications. (pp. 302-339) edited by Jesko Koehnke, James Naismith and Wilfred A. van der Donk. Cambridge: Royal Society of Chemistry. doi: 10.1039/9781788010153-00302 |
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2018 Conference Publication Is the mirror image a true reflection? Lipid chirality in the activity of the prototypic cyclotide kalata B1Henriques, Sonia Troeira, Peacock, Hayden, Benfield, Aurelie H., Wang, Conan and Craik, David (2018). Is the mirror image a true reflection? Lipid chirality in the activity of the prototypic cyclotide kalata B1. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. |
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2018 Conference Publication Development of serine protease inhibitors using the 1,2,3-triazole motif as a disulfide mimetic in the cyclic peptide sunflower trypsin inhibitor-1White, Andrew, Deveer, Simon, Swedberg, Joakim, Durek, Thomas and Craik, David (2018). Development of serine protease inhibitors using the 1,2,3-triazole motif as a disulfide mimetic in the cyclic peptide sunflower trypsin inhibitor-1. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.3127 |
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2018 Conference Publication Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxinsKaas, Quentin, Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J. and Craik, David (2018). Inhibition of nicotinic acetylcholine receptor subtypes by the ribbon isomers of alpha-conotoxins. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. |
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2018 Book Chapter Overview of NMR in drug designCraik, David J. and Peacock, Hayden (2018). Overview of NMR in drug design. Modern Magnetic Resonance. (pp. 1971-1981) edited by Graham A. Webb. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-28388-3_112 |
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2018 Conference Publication A journey alongside cyclosporin on the road to peptide oral bioavailabilityWang, Conan and Craik, David (2018). A journey alongside cyclosporin on the road to peptide oral bioavailability. 35th European Peptide Symposium, Dublin City University, Ireland, 26-31 August 2018. Oxford, United Kingdom: John Wiley & Sons. |
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2017 Journal Article Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in plantaPoon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J and Anderson, Marilyn A (2017). Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta. Journal of experimental botany, 69 (3), 633-641. doi: 10.1093/jxb/erx422 |
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2017 Journal Article Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine ReceptorsDurek, Thomas, Shelukhina, Irina V., Tae, Han-Shen, Thongyoo, Panumart, Spirova, Ekaterina N., Kudryavtsev, Denis S., Kasheverov, Igor E., Faure, Grazyna, Corringer, Pierre-Jean, Craik, David J., Adams, David J. and Tsetlin, Victor I. (2017). Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports, 7 (1) 16606, 16606. doi: 10.1038/s41598-017-16809-0 |
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2017 Journal Article Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017)Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sonia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017). Biochimica Et Biophysica Acta-Biomembranes, 1859 (11), 2277-2277. doi: 10.1016/j.bbamem.2017.08.008 |
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2017 Journal Article Redesigned spider peptide with improved antimicrobial and anticancer propertiesHenriques, Sónia Troeira, Lawrence, Nicole, Chaousis, Stephanie, Ravipati, Anjaneya S., Cheneval, Olivier, Benfield, Aurélie H., Elliott, Alysha G., Kavanagh, Angela Maria, Cooper, Matthew A., Chan, Lai Yue, Huang, Yen-Hua and Craik, David J. (2017). Redesigned spider peptide with improved antimicrobial and anticancer properties. ACS Chemical Biology, 12 (9), 2324-2334. doi: 10.1021/acschembio.7b00459 |
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2017 Journal Article Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptakeOjeda, Paola G. , Henriques, Sonia Troeira, Pan, Yijun, Nicolazzo, Joseph A., Craik, David J. and Wang, Conan K. (2017). Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake. Biopolymers, 108 (5) e23025, e23025. doi: 10.1002/bip.23025 |
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2017 Journal Article Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomerWu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017). Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 (41), 17101-17112. doi: 10.1074/jbc.M117.808386 |
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2017 Journal Article Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxinsAgwa, Akello J., Huang, Yen-Hua, Craik, David J., Henriques, Sonia T. and Schroeder, Christina I. (2017). Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins. Toxins, 9 (8) 248, 248. doi: 10.3390/toxins9080248 |
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2017 Journal Article Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffoldsCraik, David J., Lee, Meng-Han, Rehm, Fabian B.H., Tombling, Benjamin, Doffek, Benjamin and Peacock, Hayden (2017). Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic and Medicinal Chemistry, 26 (10), 2727-2737. doi: 10.1016/j.bmc.2017.08.005 |
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2017 Journal Article α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine ReceptorsWu, Yong, Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Zhangsun, Manqi, Harvey, Peta J., Craik, David J., McIntosh, J. Michael and Luo, Sulan (2017). α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry, 60 (13), 5826-5833. doi: 10.1021/acs.jmedchem.7b00546 |
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2017 Journal Article Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranesCranfield, Charles G., Henriques, Sonia Troeira, Martinac, Boris, Duckworth, Paul, Craik, David J. and Cornell, Bruce (2017). Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranes. Langmuir, 33 (26), 6630-6637. doi: 10.1021/acs.langmuir.7b01642 |
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2017 Journal Article Cyclotides as tools in chemical biologyde Veer, Simon J., Weidmann, Joachim and Craik, David J. (2017). Cyclotides as tools in chemical biology. Accounts of Chemical Research, 50 (7), 1557-1565. doi: 10.1021/acs.accounts.7b00157 |
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2017 Journal Article Cyclotides as drug design scaffoldsCraik, David J. and Du, Junqiao (2017). Cyclotides as drug design scaffolds. Current Opinion in Chemical Biology, 38, 8-16. doi: 10.1016/j.cbpa.2017.01.018 |
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2017 Journal Article Editorial overviewCraik, David J. and Henriques, Sonia Troeira (2017). Editorial overview. Current Opinion in Chemical Biology, 38, iv-vi. doi: 10.1016/j.cbpa.2017.05.012 |
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2017 Journal Article Understanding the diversity and distribution of cyclotides from plants of varied genetic originRavipati, Anjaneya S., Poth, Aaron G., Henriques, Sonia Troeira, Bhandari, Murari, Huang, Yen-Hua, Nino, Jaime, Colgrave, Michelle L. and Craik, David J. (2017). Understanding the diversity and distribution of cyclotides from plants of varied genetic origin. Journal of Natural Products, 80 (5), 1522-1530. doi: 10.1021/acs.jnatprod.7b00061 |
