|
2017 Journal Article Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sónia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochimica et Biophysica Acta. Biomembranes, 1859 (5), 835-844. doi: 10.1016/j.bbamem.2017.01.020 |
|
2017 Journal Article αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtypeZhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Wu, Yong, Craik, David J. , McIntosh, J. Michael and Luo, Sulan (2017). αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype. Neuropharmacology, 127, 243-252. doi: 10.1016/j.neuropharm.2017.04.015 |
|
2017 Journal Article Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRETKubota, Tomoya, Durek, Thomas, Dang, Bobo, Finol-Urdaneta, Rocio K., Craik, David J., Kent, Stephen B. H., French, Robert J., Bezanilla, Francisco and Correa, Ana M. (2017). Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences, 114 (10), E1857-E1865. doi: 10.1073/pnas.1700453114 |
|
2017 Journal Article Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMRGrage, Stephan L., Sani, Marc-Antoine, Cheneval, Olivier, Henriques, Sonia Troeira, Schalck, Constantin, Heinzmann, Ralf, Mylne, Joshua S., Mykhailiuk, Pavel K., Afonin, Sergii, Komarov, Igor V., Separovic, Frances, Craik, David J. and Ulrich, Anne S. (2017). Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMR. Biophysical Journal, 112 (4), 630-642. doi: 10.1016/j.bpj.2016.12.040 |
|
2017 Journal Article Cyclotide structure and function: the role of membrane binding and permeationTroeira Henriques, Sonia and Craik, David J. (2017). Cyclotide structure and function: the role of membrane binding and permeation. Biochemistry, 56 (5), 669-682. doi: 10.1021/acs.biochem.6b01212 |
|
2017 Journal Article Synthesis and protein engineering applications of cyclotidesQu, Haiou, Smithies, Bronwyn J. , Durek, Thomas and Craik, David J. (2017). Synthesis and protein engineering applications of cyclotides. Australian Journal of Chemistry, 70 (2), 152-161. doi: 10.1071/CH16589 |
|
2017 Journal Article Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffoldSwedberg, Joakim E., Li, Choi Yi, De Veer, Simon J., Wang, Conan K. and Craik, David J. (2017). Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold. Journal of Medicinal Chemistry, 60 (2), 658-667. doi: 10.1021/acs.jmedchem.6b01509 |
|
2017 Book Chapter A practical guide to structural aspects of macrocycles (NMR, x-ray, and modeling)Craik, David J., Kaas, Quentin and Wang, Conan K. (2017). A practical guide to structural aspects of macrocycles (NMR, x-ray, and modeling). Practical medicinal chemistry with macrocycles: Design, synthesis, and case studies. (pp. 25-57) edited by Eric Marsault and Mark L Peterson. Hoboken, New Jersey, United States: John Wiley & Sons. doi: 10.1002/9781119092599.ch2 |
|
2017 Journal Article Identification of survival-promoting OSIP108 peptide variants and their internalization in human cellsVerbandt, Sara, Henriques, Sónia Troeira, Spincemaille, Pieter, Harvey, Peta J., Chandhok, Gursimran, Sauer, Vanessa, De Coninck, Barbara, Cassiman, David, Craik, David J., Cammue, Bruno P. A., De Cremer, Kaat and Thevissen, Karin (2017). Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells. Mechanisms of Ageing and Development, 161 (B), 247-254. doi: 10.1016/j.mad.2016.07.013 |
|
2017 Conference Publication Small molecule and peptidic ligands as PCSK9-LDLR inhibitorsBhattacharya, Samit, Ammirati, Mark, Borzilleri, Kris, Cheneval, Olivier, Chrunyk, Boris, Craik, David, Daly, Norelle, Dullea, Robert, Griffor, Matthew, Kamlet, Adam, Limberakis, Chris, Sahasrabudhe, Parag, Liu, Shenping, Loria, Paula, Mc Clure, Kim, Menhaji-Klotz, Elnaz, Petersen, Donna, Piotrowski, David, Popovska-Gorevski, Marina, Price, David, Reyes, Allan, Ruggeri, Roger, Schroeder, Christina, Song, Kun, Swedberg, Joakim, Stock, Ingrid, Tu, Meihua and Withka, Jane (2017). Small molecule and peptidic ligands as PCSK9-LDLR inhibitors. 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Washington, DC, 20-24 August 2017 . Washington, DC, United States: American Chemical Society. |
|
2017 Book Chapter Cyclotides: plant defense toxinsOguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2017). Cyclotides: plant defense toxins. Plant toxins. (pp. 221-243) edited by P Gopalakrishnakone, Célia R Carlini and Rodrigo Ligabue-Braun. Dordrecht, The Netherlands: Springer, Dordrecht. doi: 10.1007/978-94-007-6464-4 |
|
2017 Book Chapter Cyclotides: plant defense toxinsOguis, Georgianna Kae, Kan, Meng-Wei and Craik, David J. (2017). Cyclotides: plant defense toxins. Plant toxins. (pp. 221-242) edited by P. Gopalakrishnakone, Célia Regina Carlini and Rodrigo Ligabue-Braun. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-6464-4_7 |
|
2017 Book Chapter Naturally occurring disulfide-rich cyclic peptides from plants and animals: synthesis and biosynthesisde Veer, Simon J. and Craik, David J. (2017). Naturally occurring disulfide-rich cyclic peptides from plants and animals: synthesis and biosynthesis. Chemical biology of natural products. (pp. 491-528) edited by David J. Newman, Gordon M. Cragg and Paul G. Grothaus. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315117089-13 |
|
2017 Journal Article Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamiliesAbdul Ghani, Hafiza, Henriques, Sonia Troeira, Huang, Yen-Hua, Swedberg, Joakim E. , Schroeder, Christina I. and Craik, David J. (2017). Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies. Biopolymers, 108 (1) e22927, e22927. doi: 10.1002/bip.22927 |
|
2017 Book Chapter Overview of NMR in drug designCraik, David J. and Peacock, Hayden (2017). Overview of NMR in drug design. Modern magnetic resonance. (pp. 1-11) edited by Graham A. Webb. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-28275-6_112-1 |
|
2016 Journal Article Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloidsMatsuura, Helio N., Poth, Aaron G., Yendo, Anna C. A., Fett-Neto, Arthur G. and Craik, David J. (2016). Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloids. Journal of Natural Products, 79 (12), 3006-3013. doi: 10.1021/acs.jnatprod.6b00492 |
|
2016 Journal Article Discovery and optimization of peptide macrocyclesWhite, Andrew M. and Craik, David J. (2016). Discovery and optimization of peptide macrocycles. Expert Opinion on Drug Discovery, 11 (12), 1151-1163. doi: 10.1080/17460441.2016.1245720 |
|
2016 Journal Article Characterization of a bioactive acyclotide from Palicourea rigidaPinto, Michelle F. S., Silva, Osmar N., Viana, Juilan C., Porto, William F., Migliolo, Ludovico, da Cunha, Nicolau B., Gomes Jr., Nelson, Fensterseifer, Isabel C. M., Colgrave, Michelle L., Craik, David J., Dias, Simoni C. and Franco, Octavio L. (2016). Characterization of a bioactive acyclotide from Palicourea rigida. Journal of Natural Products, 79 (11), 2767-2773. doi: 10.1021/acs.jnatprod.6b00270 |
|
2016 Journal Article Cyclic peptide oral bioavailability: lessons from the pastWang, Conan K. and Craik, David J. (2016). Cyclic peptide oral bioavailability: lessons from the past. Biopolymers, 106 (6), 901-909. doi: 10.1002/bip.22878 |
|
2016 Journal Article Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxinCarstens, Bodil B., Swedberg, Joakim, Berecki, Geza, Adams, David J., Craik, David J. and Clark, Richard J. (2016). Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers, 106 (6), 864-875. doi: 10.1002/bip.22848 |
