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Associate Professor Susannah Tye
Associate Professor

Susannah Tye

Email: 
Phone: 
+61 7 344 32493

Overview

Background

Dr. Susannah Tye joined the Queensland Brain Institute in 2017 and has established a research program within the Asia Pacific Centre for Neuromodulation (QLD, Australia). Before returning to Australia, Dr. Tye directed the Translational Neuroscience Laboratory at the Mayo Clinic (2012-2017). While there she led efforts to develop brain stimulation devices (for rodents and humans) that can quantify neural activity and neurotransmitter dynamics in the living brain. This body of work now forms the basis of the neuropsychiatric arm of the Mayo Clinic’s Deep Brain Stimulation Consortium. Her specific research expertise are in utilising voltammetric (electrochemical) recording techniques to monitor rapid, synaptic neurotransmission in the living brain.

Dr. Tye has over ten years of experience studying neuromodulation in preclinical rodent models and human patients. Her long-term goal is to bridge preclinical and clinical studies to maximise translational impact, specifically in terms of improving patient outcomes for those with severe refractory psychiatric illness. Towards this end, she maintains many international collaborations with both clinical and basic science researchers. Dr. Tye also has a longstanding interest in mentoring young scientists to help them expand their skills in preclinical and basic science research and achieve a successful research career.

Availability

Associate Professor Susannah Tye is:
Available for supervision

Qualifications

  • Doctor of Philosophy, Macquarie University

Research interests

  • Deep Brain Stimulation

  • Neuromodulation

  • Depression

  • Bipolar Disorder

  • Stress Disorders

  • Parkinson's Disease

  • Biomarkers

  • Refractory Psychiatric Illness

Research impacts

The Tye group develops and applies novel technologies to modulate neuronal function. This work helps inform our basic understanding of signalling in the brain in both health and disease, with specific implications for understanding and correcting abnormal neuronal activity and neurotransmitter dynamics in chronic, unremitting brain-based illness. Working with both local and international collaborations in across clinical, engineering, and basic science fields, we work towards the long-term goal of translating cutting-edge brain stimulation technologies to the clinic to optimise therapeutic outcomes.

Works

Search Professor Susannah Tye’s works on UQ eSpace

121 works between 2009 and 2025

121 - 121 of 121 works

2009

Conference Publication

Wireless Instantaneous Neurotransmitter Concentration Sensing System (WINCS) for intraoperative neurochemical monitoring

Kimble, Christopher J., Johnson, David M., Winter, Bruce A., Whitlock, Sidney V., Kressin, Kenneth R., Horne, April E., Robinson, Justin C., Bledsoe, Jonathan M., Tye, Susannah J., Chang, Su-Youne, Agnesi, Filippo, Griessenauer, Christoph J., Covey, Daniel, Shon, Young-Min, Bennet, Kevin E., Garris, Paul A. and Lee, Kendall H. (2009). Wireless Instantaneous Neurotransmitter Concentration Sensing System (WINCS) for intraoperative neurochemical monitoring. 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 2- 6 September, 2009. Piscataway, NJ, United States: IEEE Computer Society. doi: 10.1109/IEMBS.2009.5332773

Wireless Instantaneous Neurotransmitter Concentration Sensing System (WINCS) for intraoperative neurochemical monitoring

Funding

Current funding

  • 2026 - 2029
    An intelligent deep brain stimulation approach for treating human movement disorders
    NHMRC IDEAS Grants
    Open grant
  • 2025 - 2027
    Preclinical Evaluation of a Novel Analgesic to Improve Pain Relief for People with a Current or Past Opioid Use Disorder
    NHMRC MRFF Alcohol and Other Drugs
    Open grant
  • 2024 - 2026
    Precision Medicine Approaches for Depression and Anxiety
    The Nicol Foundation
    Open grant
  • 2023 - 2026
    Neural circuit control of effort under stress
    ARC Discovery Projects
    Open grant
  • 2021 - 2027
    Biomarker Discovery for Treatment Resistant Mood Disorders
    The Nicol Foundation
    Open grant

Past funding

  • 2023 - 2024
    Intelligent Closed Loop Neuromodulation
    Bionics Queensland Challenge
    Open grant
  • 2023
    Cell-specific control of striatal neurotransmission for mood regulation (project under NHRMC CREDIT Centre of Research Excellence administered by Deakin University)
    Deakin University
    Open grant
  • 2022
    Prefrontal Mechanisms Regulating Striatal Dopamine Release Essential for Persistent Effort
    UQ Foundation Research Excellence Awards
    Open grant
  • 2019 - 2023
    Circuit, cellular and synaptic mechanisms of nucleus accumbens deep brain stimulation
    NHMRC Project Grant
    Open grant
  • 2019
    Common Mechanisms of Anti-Suicidal Drug Action
    UQ Early Career Researcher
    Open grant

Supervision

Availability

Associate Professor Susannah Tye is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Prefrontal Mechanisms Regulating Striatal Dopamine During Persistent Effort

    Principal Advisor

    Other advisors: Dr Roger Bitencourt Varela

  • Doctor Philosophy

    Neurofeedback an intervention for emotion regulation and attention in children and adolescents that have Down syndrome.

    Principal Advisor

    Other advisors: Professor Rhonda Faragher

  • Doctor Philosophy

    Circadian mechanisms of mood regulation

    Principal Advisor

    Other advisors: Dr Roger Bitencourt Varela

  • Doctor Philosophy

    Development of precision medicine biomarkers for ketamine as a treatment for TRD and PTSD

    Principal Advisor

    Other advisors: Professor Fatima Nasrallah

  • Master Philosophy

    Predictive Biobehavioural Markers of Deep Brain Stimulation Efficacy

    Principal Advisor

    Other advisors: Professor Pankaj Sah

  • Doctor Philosophy

    The development of precision medical care for the use of ketamine as a treatment for Australian Veterans with TRD and PTSD

    Associate Advisor

    Other advisors: Professor Fatima Nasrallah

  • Doctor Philosophy

    Modelling neural circuit control of effort under stress

    Associate Advisor

  • Master Philosophy

    Biopsychosocial Adaptations and Early OperationalOutcomes: Longitudinal Neurophysiological tracking of Police Recruits' transition to Operational Policing

    Associate Advisor

    Other advisors: Associate Professor Sarah Bennett

Completed supervision

Media

Enquiries

For media enquiries about Associate Professor Susannah Tye's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au