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2026

Conference Publication

An online library of animal models: finding the best models and assays for depression, anxiety, and psychosis

Mc Donnell, Conor, Milton, Laura, Thivisol, Ulysse, Foldi, Claire, Kesby, James, Tye, Susannah, Boyce, Niall, Hill, Rachel and Sundram, Suresh (2026). An Online Library of Animal Models: Finding the Best Models and Assays for Depression, Anxiety, and Psychosis. 81st Annual Meeting of the Society-of-Biological-Psychiatry, New York Ny, Apr 30-May 02, 2026. NEW YORK: ELSEVIER SCIENCE INC.

An online library of animal models: finding the best models and assays for depression, anxiety, and psychosis

2026

Conference Publication

Leveraging expert and lived experience of mental ill health perspectives to traverse the research translational gap

Milton, Laura, McDonnell, Conor, Thivisol, Ulysse, Foldi, Claire, Kesby, James, Tye, Susannah, Cruickshank, Heather, Hedberg, Anette, Boyce, Niall, Hill, Rachel and Sundram, Suresh (2026). 589. Leveraging Expert and Lived Experience of Mental Ill Health Perspectives to Traverse the Research Translational Gap. Biological Psychiatry, 99 (10), S352. doi: 10.1016/j.biopsych.2026.03.823

Leveraging expert and lived experience of mental ill health perspectives to traverse the research translational gap

2026

Conference Publication

Leveraging expert and lived experience of mental ill health perspectives to traverse the research translational gap

Milton, Laura, McDonnell, Conor, Thivisol, Ulysse, Foldi, Claire, Kesby, James, Tye, Susannah, Cruickshank, Heather, Hedberg, Anette, Boyce, Niall, Hill, Rachel and Sundram, Suresh (2026). Leveraging expert and lived experience of mental ill health perspectives to traverse the research translational gap. 81st Annual Meeting of the Society-of-Biological-Psychiatry, New York, NY USA, 30 April-2 May 2026. Philadelphia, PA United States: Elsevier.

Leveraging expert and lived experience of mental ill health perspectives to traverse the research translational gap

2026

Conference Publication

Plasma lactate as a metabolic predictor of ketamine response in treatment-resistant depression

Scaini, Giselli, Pinheiro Gusmao, Camilla Teixeira, Carbajal Tamez, Marcela C., Cordeiro, Rafaela C., de Quevedo, Joao, Tye, Susannah, Elmallakh, Rifaat, Parikh, Sagar, Bobo, William, Goes, Fernando S., Vande Voort, Jennifer L., Nykamp, Louis, Balwinder, Singh, Nelson, Erik, Thase, Michael, Frye, Mark, Greden, John and Achtyes, Eric (2026). 198. Plasma Lactate as a Metabolic Predictor of Ketamine Response in Treatment-Resistant Depression. Biological Psychiatry, 99 (10), S183-S184. doi: 10.1016/j.biopsych.2026.03.432

Plasma lactate as a metabolic predictor of ketamine response in treatment-resistant depression

2026

Conference Publication

Unlocking clinical mechanisms through animal models: a Wellcome Initiative

Tye, Susannah, Mayberg, Helen, Sundram, Suresh, Hill, Rachel, Erhardt, Sophie, Ahmari, Susanne and Young, Jared (2026). Unlocking clinical mechanisms through animal models: a Wellcome Initiative. 64th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Nassau, Bahamas, 12-15 January 2026. London, United Kingdom: Nature Publishing Group. doi: 10.1038/s41386-025-02278-x

Unlocking clinical mechanisms through animal models: a Wellcome Initiative

2025

Conference Publication

Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar Disorder

Macpherson, Heather, Varela, Roger, Daygon, Venea, Kesby, James, Cui, Xiaoying and Tye, Susannah (2025). Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar Disorder. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing.

Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar Disorder

2025

Conference Publication

Unpredictable Circadian Disturbance Induces Bipolar-Like Behavioural and Immunometabolic Dysregulation in Rats

Macpherson, Heather, Varela, Roger, McCullough, Sebastian, Houghton, Tristan, Chawla, Isha, Wang, Ning, Daygon, Venea, Cui, Xiaoying and Tye, Susannah (2025). Unpredictable Circadian Disturbance Induces Bipolar-Like Behavioural and Immunometabolic Dysregulation in Rats. 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17-19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell.

Unpredictable Circadian Disturbance Induces Bipolar-Like Behavioural and Immunometabolic Dysregulation in Rats

2025

Conference Publication

Exploring the Role of Antidepressants on Mitochondrial Energetics and Risk of Antidepressant Induced Mania

Resendez, Manuel Gardea, Coombes, Brandon, Veldic, Marin, Tye, Susannah, Romo-Nava, Francisco, Ozerdem, Aysegul, Prieto, Miguel, Cuellar-Barboza, Alfredo, Nunez, Nicolas, Miola, Alessandro, McElroy, Susan, Biernacka, Joanna, Morava, Eva, Kozicz, Tamas and Frye, Mark (2025). Exploring the Role of Antidepressants on Mitochondrial Energetics and Risk of Antidepressant Induced Mania. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japa, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing.

Exploring the Role of Antidepressants on Mitochondrial Energetics and Risk of Antidepressant Induced Mania

2025

Conference Publication

Bioenergetic Dysregulation in Peripheral Immune Cells: Links to Anhedonia and Fatigue in Depressed Young Adults

Varela, Roger, Cullen, Kathryn, Morath, Brooke and Tye, Susannah (2025). Bioenergetic Dysregulation in Peripheral Immune Cells: Links to Anhedonia and Fatigue in Depressed Young Adults. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing.

Bioenergetic Dysregulation in Peripheral Immune Cells: Links to Anhedonia and Fatigue in Depressed Young Adults

2025

Conference Publication

Immunometabolic dysfunction and dopaminergic impairment in an animal model of treatment-resistant anhedonia: implications for bipolar disorder

Varela, Roger, Macpherson, Heather, Houghton, Tristan, Yates, Clarissa, Yates, Nathanael, Daygon, Dara and Tye, Susannah (2025). Immunometabolic dysfunction and dopaminergic impairment in an animal model of treatment-resistant anhedonia: implications for bipolar disorder. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing.

Immunometabolic dysfunction and dopaminergic impairment in an animal model of treatment-resistant anhedonia: implications for bipolar disorder

2024

Conference Publication

Inflammation in combination with metabolic deficits underly Anhedonia-like behavior in treatment resistant male rats

Varela, Roger, Macpherson, Heather, Houghton, Tristan, Yates, Clarissa, Yates, Nathanael, Daygon, Dara and Tye, Susannah (2024). Inflammation in combination with metabolic deficits underly Anhedonia-like behavior in treatment resistant male rats. ACNP 63rd Annual Meeting: Poster Abstracts P609-P914, Phoenix, AZ United States, 8-11 December 2024. London, United Kingdom: Nature Publishing Group.

Inflammation in combination with metabolic deficits underly Anhedonia-like behavior in treatment resistant male rats

2023

Conference Publication

Circuit-Based Manipulation of Striatal Dopamine: A State-Dependent and Mood Stabilizing Approach

Tye, Susannah (2023). Circuit-Based Manipulation of Striatal Dopamine: A State-Dependent and Mood Stabilizing Approach. 62nd Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Tampa Fl, Dec 03-06, 2023. LONDON: SPRINGERNATURE.

Circuit-Based Manipulation of Striatal Dopamine: A State-Dependent and Mood Stabilizing Approach

2023

Conference Publication

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

Tye, Susannah, Price, Joshua, Walker, Adam, Sutor, Shari, Erhardt, Sophie, Schwieler, Lilly, Cullen, Kathryn, Voort, Jennifer Vande, Frye, Mark, Bobo, William and Shiroma, Paulo (2023). Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression. NEW YORK: ELSEVIER SCIENCE INC.

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

2023

Conference Publication

PRECISION PSYCHIATRY IN MILITARY MENTAL HEALTH CARE

Tye, S., Nasrallah, Fatima and Lim, Alex (2023). PRECISION PSYCHIATRY IN MILITARY MENTAL HEALTH CARE. LONDON: SAGE PUBLICATIONS LTD.

PRECISION PSYCHIATRY IN MILITARY MENTAL HEALTH CARE

2023

Conference Publication

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

Tye, Susannah, Price, Joshua, Walker, Adam, Sutor, Shari, Erhardt, Sophie, Schwieler, Lilly, Cullen, Kathryn, Voort, Jennifer Vande, Frye, Mark, Bobo, William and Shiroma, Paulo (2023). Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression. 78th Annual Meeting of the Society of Biological Psychiatry, San Diego, CA United States, 27-29 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.biopsych.2023.02.076

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

2023

Conference Publication

Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression

Voort, Jennifer Vande, Singh, Balwinder, Riva-Posse, Patricio, Erhardt, Sophie, Schwieler, Lilly, Pazdernik, Vanessa, Frye, Mark and Tye, Susannah (2023). Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression. NEW YORK: ELSEVIER SCIENCE INC.

Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression

2023

Conference Publication

Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression

Voort, Jennifer Vande, Singh, Balwinder, Riva-Posse, Patricio, Erhardt, Sophie, Schwieler, Lilly, Pazdernik, Vanessa, Frye, Mark and Tye, Susannah (2023). Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression. 78th Annual Meeting of the Society of Biological Psychiatry, San Diego, CA United States, 27-29 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.biopsych.2023.02.077

Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression

2022

Conference Publication

Inflammation moderates antidepressant response to ketamine in a rodent model of treatment-resistant depression: bioenergetic and inflammatory markers of response

Tye, Susannah, Price, J. Blair, Walker, Adam, Kruse, Jennifer, Cullen, Kathryn, Frye, Mark, Schwieler, Lilly and Erhardt, Sophie (2022). Inflammation Moderates Antidepressant Response to Ketamine in a Rodent Model of Treatment-Resistant Depression: Bioenergetic and Inflammatory Markers of Response. 61st Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Phoenix Az, Dec 04-07, 2022. LONDON: SPRINGERNATURE.

Inflammation moderates antidepressant response to ketamine in a rodent model of treatment-resistant depression: bioenergetic and inflammatory markers of response

2019

Conference Publication

Molecular, cellular, and bioenergetic actions of ketamine and lithium combinatorial treatment in antidepressant resistant rats

Blair, Joshua, Morath, Brooke, Butters, Kim, Frye, Mark, McGee, Sean and Tye, Susannah (2019). Molecular, cellular, and bioenergetic actions of ketamine and lithium combinatorial treatment in antidepressant resistant rats. 58th Annual Meeting of the American College of Neuropsychopharmacology , Orlando, Florida, 8-11 December 2019 . London, United Kingdom: Nature Publishing Group.

Molecular, cellular, and bioenergetic actions of ketamine and lithium combinatorial treatment in antidepressant resistant rats

2019

Conference Publication

Antidepressant and antimanic effects of deep brain stimulation of the ventral tegmental area

Varella, R. B., Boschen, S. L., Blaha, C. D., Chye, N., Ghandi, K., Valvassori, S. S. and Tye, S. J. (2019). Antidepressant and antimanic effects of deep brain stimulation of the ventral tegmental area. 21st Annual ISBD Conference on Global Advances in Bipolar Disorder and Depression, Sydney Australia, Mar 20-23, 2019. HOBOKEN: WILEY. doi: 10.1111/bdi.12745

Antidepressant and antimanic effects of deep brain stimulation of the ventral tegmental area