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2026 Journal Article Deep brain stimulation of the nucleus accumbens modulates effort-based decision-making and phasic dopamine release in male Wistar ratsMcCullough, Sebastian, Varela, Roger B., Houghton, Tristan, Cruickshank, Heather and Tye, Susannah J. (2026). Deep brain stimulation of the nucleus accumbens modulates effort-based decision-making and phasic dopamine release in male Wistar rats. Journal of Neurochemistry, 170 (6) e70485. doi: 10.1111/jnc.70485 |
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2026 Conference Publication Leveraging expert and lived experience of mental ill health perspectives to traverse the research translational gapMilton, Laura, McDonnell, Conor, Thivisol, Ulysse, Foldi, Claire, Kesby, James, Tye, Susannah, Cruickshank, Heather, Hedberg, Anette, Boyce, Niall, Hill, Rachel and Sundram, Suresh (2026). 589. Leveraging Expert and Lived Experience of Mental Ill Health Perspectives to Traverse the Research Translational Gap. Biological Psychiatry, 99 (10), S352. doi: 10.1016/j.biopsych.2026.03.823 |
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2026 Journal Article 198. Plasma Lactate as a Metabolic Predictor of Ketamine Response in Treatment-Resistant DepressionScaini, Giselli, Pinheiro Gusmao, Camilla Teixeira, Carbajal Tamez, Marcela C., Cordeiro, Rafaela C., de Quevedo, Joao, Tye, Susannah, Elmallakh, Rifaat, Parikh, Sagar, Bobo, William, Goes, Fernando S., Vande Voort, Jennifer L., Nykamp, Louis, Balwinder, Singh, Nelson, Erik, Thase, Michael, Frye, Mark, Greden, John and Achtyes, Eric (2026). 198. Plasma Lactate as a Metabolic Predictor of Ketamine Response in Treatment-Resistant Depression. Biological Psychiatry, 99 (10), S183-S184. doi: 10.1016/j.biopsych.2026.03.432 |
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2026 Journal Article 220. An Online Library of Animal Models: Finding the Best Models and Assays for Depression, Anxiety, and PsychosisDonnell, Conor Mc, Milton, Laura, Thivisol, Ulysse, Foldi, Claire, Kesby, James, Tye, Susannah, Boyce, Niall, Hill, Rachel and Sundram, Suresh (2026). 220. An Online Library of Animal Models: Finding the Best Models and Assays for Depression, Anxiety, and Psychosis. Biological Psychiatry, 99 (10), S193. doi: 10.1016/j.biopsych.2026.03.454 |
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2026 Journal Article Melatonin in bipolar disorderMacpherson, Heather K., Varela, Roger B., Truong, Trang T. T., Walder, Ken, Berk, Michael and Tye, Susannah J. (2026). Melatonin in bipolar disorder. Journal of Affective Disorders, 398 120871, 1-24. doi: 10.1016/j.jad.2025.120871 |
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2026 Journal Article ATP bioenergetics and fatigue in young adults with and without major depressionCullen, Kathryn R., Tye, Susannah J., Klimes-Dougan, Bonnie, Wiesner, Hannes M., Varela, Roger B., Morath, Brooke, Zhang, Lin, Chen, Wei and Zhu, Xiao-Hong (2026). ATP bioenergetics and fatigue in young adults with and without major depression. Translational Psychiatry, 16 (1) 158. doi: 10.1038/s41398-026-03904-y |
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2026 Journal Article Of mice, molecules and mental health: establishment of the consortium for preclinical psychiatric research to find solutions to the translational gapConsortium for Preclinical Psychiatric Research, Hill, Rachel A., Bastawy, Eslam M., Berk, Michael, Brown, Robyn M., Burne, Thomas H., Chesworth, Rose, Clark, Scott R., Clemens, Kelly J., Cui, Xiaoying, Dunn, Ariel L., Eratne, Dhamidhu, Foldi, Claire J., Gatt, Justine M., Gubert, Carolina, Gurvich, Caroline, Hannan, Anthony J., Harms, Lauren, Hill-Yardin, Elisa L., Jaehne, Emily J., Jawahar, Magdalene C., Jones, Nigel C., Kang, Matthew JY, Karl, Tim, Kesby, James P., Kim, Jee Hyun, Lawrence, Andrew J., Cruickshank, Heather, Manning, Elizabeth E. ... Sundram, Suresh (2026). Of mice, molecules and mental health: establishment of the consortium for preclinical psychiatric research to find solutions to the translational gap. Molecular Psychiatry, 31 (2), 1167-1170. doi: 10.1038/s41380-025-03361-x |
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2026 Conference Publication Unlocking clinical mechanisms through animal models: a Wellcome InitiativeTye, Susannah, Mayberg, Helen, Sundram, Suresh, Hill, Rachel, Erhardt, Sophie, Ahmari, Susanne and Young, Jared (2026). Unlocking clinical mechanisms through animal models: a Wellcome Initiative. 64th Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Nassau, Bahamas, 12-15 January 2026. London, United Kingdom: Nature Publishing Group. doi: 10.1038/s41386-025-02278-x |
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2025 Journal Article Novel psychedelic interventions for post-traumatic stress disorder and their promise for precision medicineDodds, Charles, Dawson, Rachelle, Lim, Alexander, Tye, Susannah and Nasrallah, Fatima (2025). Novel psychedelic interventions for post-traumatic stress disorder and their promise for precision medicine. Therapeutic Advances in Psychopharmacology, 15 20451253251396255, 1-25. doi: 10.1177/20451253251396255 |
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2025 Journal Article Fueling the future: brain bioenergetics as a driver of neurodevelopment and mental health trajectoriesTye, Susannah J. and Cullen, Kathryn R. (2025). Fueling the future: brain bioenergetics as a driver of neurodevelopment and mental health trajectories. Neuropsychopharmacology, 51 (1), 334-336. doi: 10.1038/s41386-025-02230-z |
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2025 Other Outputs Unpredictable circadian rhythm disruption in Wistar rats: biological and behavioural changes reflecting bipolar disorder pathophysiologyMacPherson, Heather, Varela, Roger B., McCullough, Sebastian C., Houghton, Tristan, Chawla, Isha, Wang, Ning, Daygon, Venea Dara, Cui, Xiaoying and Tye, Susannah J. (2025). Unpredictable circadian rhythm disruption in Wistar rats: biological and behavioural changes reflecting bipolar disorder pathophysiology. doi: 10.1101/2025.09.06.674601 |
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2025 Other Outputs Melatonin mitigates oxidative stress and metabolic dysfunction induced by interleukin-6 and dopamine in SH-SY5Y cellsMacPherson, Heather, Varela, Roger B., Daygon, Venea Dara, Kesby, James P., Cui, Xiaoying and Tye, Susannah J. (2025). Melatonin mitigates oxidative stress and metabolic dysfunction induced by interleukin-6 and dopamine in SH-SY5Y cells. doi: 10.1101/2025.09.03.673920 |
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2025 Other Outputs Investigating the role of melatonin in bipolar disorder using transcriptomicsMacPherson, Heather, Truong, Trang T. T., Berk, Michael, Walder, Ken and Tye, Susannah J. (2025). Investigating the role of melatonin in bipolar disorder using transcriptomics. doi: 10.1101/2025.09.03.673928 |
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2025 Conference Publication Immunometabolic dysfunction and dopaminergic impairment in an animal model of treatment-resistant anhedonia: implications for bipolar disorderVarela, Roger, Macpherson, Heather, Houghton, Tristan, Yates, Clarissa, Yates, Nathanael, Daygon, Dara and Tye, Susannah (2025). Immunometabolic dysfunction and dopaminergic impairment in an animal model of treatment-resistant anhedonia: implications for bipolar disorder. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing. |
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2025 Conference Publication Unpredictable Circadian Disturbance Induces Bipolar-Like Behavioural and Immunometabolic Dysregulation in RatsMacpherson, Heather, Varela, Roger, McCullough, Sebastian, Houghton, Tristan, Chawla, Isha, Wang, Ning, Daygon, Venea, Cui, Xiaoying and Tye, Susannah (2025). Unpredictable Circadian Disturbance Induces Bipolar-Like Behavioural and Immunometabolic Dysregulation in Rats. 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17-19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell. |
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2025 Conference Publication Exploring the Role of Antidepressants on Mitochondrial Energetics and Risk of Antidepressant Induced ManiaResendez, Manuel Gardea, Coombes, Brandon, Veldic, Marin, Tye, Susannah, Romo-Nava, Francisco, Ozerdem, Aysegul, Prieto, Miguel, Cuellar-Barboza, Alfredo, Nunez, Nicolas, Miola, Alessandro, McElroy, Susan, Biernacka, Joanna, Morava, Eva, Kozicz, Tamas and Frye, Mark (2025). Exploring the Role of Antidepressants on Mitochondrial Energetics and Risk of Antidepressant Induced Mania. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japa, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing. |
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2025 Conference Publication Bioenergetic Dysregulation in Peripheral Immune Cells: Links to Anhedonia and Fatigue in Depressed Young AdultsVarela, Roger, Cullen, Kathryn, Morath, Brooke and Tye, Susannah (2025). Bioenergetic Dysregulation in Peripheral Immune Cells: Links to Anhedonia and Fatigue in Depressed Young Adults. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing. |
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2025 Conference Publication Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar DisorderMacpherson, Heather, Varela, Roger, Daygon, Venea, Kesby, James, Cui, Xiaoying and Tye, Susannah (2025). Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar Disorder. The 27th Annual Conference of the International Society for Bipolar Disorders, Chiba, Japan, 17 – 19 September 2025. Hoboken, NJ, United States: Wiley-Blackwell Publishing. |
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2025 Journal Article Inflammation and metabolic dysfunction underly anhedonia-like behavior in antidepressant resistant male ratsVarela, Roger B., Macpherson, Heather, Walker, Adam J., Houghton, Tristan, Yates, Clarissa, Yates, Nathanael J., Daygon, Dara and Tye, Susannah J. (2025). Inflammation and metabolic dysfunction underly anhedonia-like behavior in antidepressant resistant male rats. Brain, Behavior, and Immunity, 127, 170-182. doi: 10.1016/j.bbi.2025.03.001 |
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2024 Conference Publication Inflammation in combination with metabolic deficits underly Anhedonia-like behavior in treatment resistant male ratsVarela, Roger, Macpherson, Heather, Houghton, Tristan, Yates, Clarissa, Yates, Nathanael, Daygon, Dara and Tye, Susannah (2024). Inflammation in combination with metabolic deficits underly Anhedonia-like behavior in treatment resistant male rats. ACNP 63rd Annual Meeting: Poster Abstracts P609-P914, Phoenix, AZ United States, 8-11 December 2024. London, United Kingdom: Nature Publishing Group. |
