Skip to menu Skip to content Skip to footer

2023

Conference Publication

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

Tye, Susannah, Price, Joshua, Walker, Adam, Sutor, Shari, Erhardt, Sophie, Schwieler, Lilly, Cullen, Kathryn, Voort, Jennifer Vande, Frye, Mark, Bobo, William and Shiroma, Paulo (2023). Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression. 78th Annual Meeting of the Society of Biological Psychiatry, San Diego, CA United States, 27-29 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.biopsych.2023.02.076

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

2023

Conference Publication

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

Tye, Susannah, Price, Joshua, Walker, Adam, Sutor, Shari, Erhardt, Sophie, Schwieler, Lilly, Cullen, Kathryn, Voort, Jennifer Vande, Frye, Mark, Bobo, William and Shiroma, Paulo (2023). Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression. NEW YORK: ELSEVIER SCIENCE INC.

Critical Role of Insulin as an Immunomodulatory Target in Treatment Resistant Depression

2023

Conference Publication

Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression

Voort, Jennifer Vande, Singh, Balwinder, Riva-Posse, Patricio, Erhardt, Sophie, Schwieler, Lilly, Pazdernik, Vanessa, Frye, Mark and Tye, Susannah (2023). Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression. 78th Annual Meeting of the Society of Biological Psychiatry, San Diego, CA United States, 27-29 April 2023. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.biopsych.2023.02.077

Ketamine Associated Change in Anhedonia and Suicidal Ideation are Associated With Peripheral Immune Cell mTOR Expression and Kynurenine Levels and Treatment Resistant Depression

2023

Conference Publication

PRECISION PSYCHIATRY IN MILITARY MENTAL HEALTH CARE

Tye, S., Nasrallah, Fatima and Lim, Alex (2023). PRECISION PSYCHIATRY IN MILITARY MENTAL HEALTH CARE. LONDON: SAGE PUBLICATIONS LTD.

PRECISION PSYCHIATRY IN MILITARY MENTAL HEALTH CARE

2023

Journal Article

High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens

Yuen, Jason, Goyal, Abhinav, Rusheen, Aaron E., Kouzani, Abbas Z., Berk, Michael, Kim, Jee Hyun, Tye, Susannah J., Blaha, Charles D., Bennet, Kevin E., Lee, Kendall H., Shin, Hojin and Oh, Yoonbae (2023). High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in Neuroscience, 17 1061578, 1-12. doi: 10.3389/fnins.2023.1061578

High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens

2023

Journal Article

Ketamine-associated change in anhedonia and mTOR expression in treatment-resistant depression

Singh, Balwinder, Vande Voort, Jennifer L., Riva-Posse, Patricio, Pazdernik, Vanessa M., Frye, Mark A. and Tye, Susannah J. (2023). Ketamine-associated change in anhedonia and mTOR expression in treatment-resistant depression. Biological Psychiatry, 93 (12), e65-e68. doi: 10.1016/j.biopsych.2022.10.007

Ketamine-associated change in anhedonia and mTOR expression in treatment-resistant depression

2022

Journal Article

Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania

Gardea-Resendez, Manuel, Coombes, Brandon J., Veldic, Marin, Tye, Susannah J., Romo-Nava, Francisco, Ozerdem, Aysegul, Prieto, Miguel L., Cuellar-Barboza, Alfredo, Nunez, Nicolas A., Singh, Balwinder, Pendegraft, Richard S., Miola, Alessandro, McElroy, Susan L., Biernacka, Joanna M., Morava, Eva, Kozicz, Tamas and Frye, Mark A. (2022). Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania. Molecular Psychiatry, 28 (3), 1020-1026. doi: 10.1038/s41380-022-01888-x

Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania

2022

Journal Article

Interleukin-8 and depressive responses to an inflammatory challenge: secondary analysis of a randomized controlled trial

Kruse, Jennifer L., Boyle, Chloe C., Olmstead, Richard, Breen, Elizabeth C., Tye, Susannah J., Eisenberger, Naomi I. and Irwin, Michael R. (2022). Interleukin-8 and depressive responses to an inflammatory challenge: secondary analysis of a randomized controlled trial. Scientific Reports, 12 (1) 12627, 1-9. doi: 10.1038/s41598-022-16364-3

Interleukin-8 and depressive responses to an inflammatory challenge: secondary analysis of a randomized controlled trial

2022

Journal Article

Deep brain stimulation for addictive disorders—where are we now?

Yuen, Jason, Kouzani, Abbas Z., Berk, Michael, Tye, Susannah J., Rusheen, Aaron E., Blaha, Charles D., Bennet, Kevin E., Lee, Kendall H., Shin, Hojin, Kim, Jee Hyun and Oh, Yoonbae (2022). Deep brain stimulation for addictive disorders—where are we now?. Neurotherapeutics, 19 (4), 1193-1215. doi: 10.1007/s13311-022-01229-4

Deep brain stimulation for addictive disorders—where are we now?

2022

Journal Article

Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications

Varela, Roger B., Cararo, José Henrique, Tye, Susannah J., Carvalho, Andre F., Valvassori, Samira S., Fries, Gabriel R. and Quevedo, João (2022). Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications. Neuroscience and Biobehavioral Reviews, 135 104579, 104579. doi: 10.1016/j.neubiorev.2022.104579

Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications

2022

Journal Article

Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens

Yuen, Jason, Goyal, Abhinav, Rusheen, Aaron E., Kouzani, Abbas Z., Berk, Michael, Kim, Jee Hyun, Tye, Susannah J., Blaha, Charles D., Bennet, Kevin E., Lee, Kendall H., Oh, Yoonbae and Shin, Hojin (2022). Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens. Journal of Neurophysiology, 127 (3), 714-724. doi: 10.1152/jn.00420.2021

Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens

2022

Journal Article

Dynamic insulin-stimulated mTOR/GSK3 signaling in peripheral immune cells: preliminary evidence for an association with lithium response in bipolar disorder

Tye, Susannah J., Borreggine, Kristin, Price, J. Blair, Sutor, Shari L., Cuéllar-Barboza, Alfredo B., McElroy, Susan L., Biernacka, Joanna M. and Frye, Mark A. (2022). Dynamic insulin-stimulated mTOR/GSK3 signaling in peripheral immune cells: preliminary evidence for an association with lithium response in bipolar disorder. Bipolar Disorders, 24 (1) bdi.13081, 1-9. doi: 10.1111/bdi.13081

Dynamic insulin-stimulated mTOR/GSK3 signaling in peripheral immune cells: preliminary evidence for an association with lithium response in bipolar disorder

2022

Book Chapter

Modeling treatment-resistant depression in the preclinical setting

Tye, Susannah, Yates, Clarissa G. and Postorivo, Danielle (2022). Modeling treatment-resistant depression in the preclinical setting. Managing treatment-resistant depression: road to novel therapeutics. (pp. 61-80) edited by Joao Quevedo, Patricio Riva-Posse and William V. Bobo. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-824067-0.00005-0

Modeling treatment-resistant depression in the preclinical setting

2021

Journal Article

Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression

Price, J. Blair, Yates, Clarissa G., Morath, Brooke A., Van De Wakker, Sam K., Yates, Nathanael J., Butters, Kim, Frye, Mark A., McGee, Sean L. and Tye, Susannah J. (2021). Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression. Translational Psychiatry, 11 (1) 598, 598. doi: 10.1038/s41398-021-01716-w

Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression

2021

Journal Article

Modulating neuroplasticity: lessons learned from antidepressants and emerging novel therapeutics

Yates, Clarissa, Kruse, Jennifer L., Price, J. Blair, Robertson, Avril A. B. and Tye, Susannah J. (2021). Modulating neuroplasticity: lessons learned from antidepressants and emerging novel therapeutics. Current Treatment Options in Psychiatry, 8 (4), 229-257. doi: 10.1007/s40501-021-00249-9

Modulating neuroplasticity: lessons learned from antidepressants and emerging novel therapeutics

2021

Journal Article

Interleukin-8 and lower severity of depression in females, but not males, with treatment-resistant depression

Kruse, Jennifer L., Olmstead, Richard, Hellemann, Gerhard, Breen, Elizabeth C., Tye, Susannah J., Brooks, John O., Wade, Benjamin, Congdon, Eliza, Espinoza, Randall, Narr, Katherine L. and Irwin, Michael R. (2021). Interleukin-8 and lower severity of depression in females, but not males, with treatment-resistant depression. Journal of Psychiatric Research, 140, 350-356. doi: 10.1016/j.jpsychires.2021.06.009

Interleukin-8 and lower severity of depression in females, but not males, with treatment-resistant depression

2021

Journal Article

Mood regulatory actions of active and sham nucleus accumbens deep brain stimulation in antidepressant resistant rats

Kale, Rajas P., Nguyen, Thanh Thanh L., Price, J. Blair, Yates, Nathanael J., Walder, Ken, Berk, Michael, Sillitoe, Roy V., Kouzani, Abbas Z. and Tye, Susannah J. (2021). Mood regulatory actions of active and sham nucleus accumbens deep brain stimulation in antidepressant resistant rats. Frontiers in Human Neuroscience, 15 644921, 644921. doi: 10.3389/fnhum.2021.644921

Mood regulatory actions of active and sham nucleus accumbens deep brain stimulation in antidepressant resistant rats

2021

Journal Article

Cocaine-induced changes in tonic dopamine concentrations measured using multiple-cyclic square wave voltammetry in vivo

Yuen, Jason, Goyal, Abhinav, Rusheen, Aaron E., Kouzani, Abbas Z., Berk, Michael, Kim, Jee Hyun, Tye, Susannah J., Blaha, Charles D., Bennet, Kevin E., Jang, Dong-Pyo, Lee, Kendall H., Shin, Hojin and Oh, Yoonbae (2021). Cocaine-induced changes in tonic dopamine concentrations measured using multiple-cyclic square wave voltammetry in vivo. Frontiers in Pharmacology, 12 705254, 705254. doi: 10.3389/fphar.2021.705254

Cocaine-induced changes in tonic dopamine concentrations measured using multiple-cyclic square wave voltammetry in vivo

2021

Journal Article

Inflammatory mechanisms in Parkinson’s disease: from pathogenesis to targeted therapies

Lee, Stellina Y. H., Yates, Nathanael J. and Tye, Susannah J. (2021). Inflammatory mechanisms in Parkinson’s disease: from pathogenesis to targeted therapies. The Neuroscientist, 28 (5) 1073858421992265, 1073858421992265-506. doi: 10.1177/1073858421992265

Inflammatory mechanisms in Parkinson’s disease: from pathogenesis to targeted therapies

2021

Journal Article

Novel antidepressant approaches for refractory depression

Postorivo, Danielle and Tye, Susannah J. (2021). Novel antidepressant approaches for refractory depression. Current Treatment Options in Psychiatry, 8 (3), 141-157. doi: 10.1007/s40501-021-00246-y

Novel antidepressant approaches for refractory depression