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2023 Journal Article 150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibilityWu, Yeda, Goleva, Slavina B., Breidenbach, Lindsay B., Kim, Minsoo, MacGregor, Stuart, Gandal, Michael J., Davis, Lea K. and Wray, Naomi R. (2023). 150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility. Cell Genomics, 3 (7) 100326, 1-24. doi: 10.1016/j.xgen.2023.100326 |
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2023 Journal Article Rare genetic variants underlie outlying levels of DNA methylation and gene-expressionChundru, V. Kartik, Marioni, Riccardo E., Pendergast, James G. D., Lin, Tian, Beveridge, Allan J., Martin, Nicholas G, Montgomery, Grant W., Hume, David A., Deary, Ian J., Visscher, Peter M., Wray, Naomi R. and McRae, Allan F. (2023). Rare genetic variants underlie outlying levels of DNA methylation and gene-expression. Human Molecular Genetics, 32 (11), 1912-1921. doi: 10.1093/hmg/ddad028 |
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2023 Journal Article Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophreniaHsu, Yu-Han H., Pintacuda, Greta, Liu, Ruize, Nacu, Eugeniu, Kim, April, Tsafou, Kalliopi, Petrossian, Natalie, Crotty, William, Suh, Jung Min, Riseman, Jackson, Martin, Jacqueline M., Biagini, Julia C., Mena, Daya, Ching, Joshua K.T., Malolepsza, Edyta, Li, Taibo, Singh, Tarjinder, Ge, Tian, Egri, Shawn B., Tanenbaum, Benjamin, Stanclift, Caroline R., Apffel, Annie M., Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil ... Lage, Kasper (2023). Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience, 26 (5) 106701, 1-28. doi: 10.1016/j.isci.2023.106701 |
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2023 Journal Article Leveraging base-pair mammalian constraint to understand genetic variation and human diseaseSullivan, Patrick F., Meadows, Jennifer R. S., Gazal, Steven, Phan, BaDoi N., Li, Xue, Genereux, Diane P., Dong, Michael X., Bianchi, Matteo, Andrews, Gregory, Sakthikumar, Sharadha, Nordin, Jessika, Roy, Ananya, Christmas, Matthew J., Marinescu, Voichita D., Wang, Chao, Wallerman, Ola, Xue, James, Yao, Shuyang, Sun, Quan, Szatkiewicz, Jin, Wen, Jia, Huckins, Laura M., Lawler, Alyssa, Keough, Kathleen C., Zheng, Zhili, Zeng, Jian, Wray, Naomi R., Li, Yun, Johnson, Jessica ... Zoonomia Consortium§ (2023). Leveraging base-pair mammalian constraint to understand genetic variation and human disease. Science, 380 (6643) eabn2937, 1-12. doi: 10.1126/science.abn2937 |
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2023 Journal Article Interactions between the lipidome and genetic and environmental factors in autismYap, Chloe X., Henders, Anjali K., Alvares, Gail A., Giles, Corey, Huynh, Kevin, Nguyen, Anh, Wallace, Leanne, McLaren, Tiana, Yang, Yuanhao, Hernandez, Leanna M., Gandal, Michael J., Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Strike, Lachlan T. ... The Busselton Health Study Investigators (2023). Interactions between the lipidome and genetic and environmental factors in autism. Nature Medicine, 29 (4), 936-949. doi: 10.1038/s41591-023-02271-1 |
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2023 Journal Article Timing of antidepressant discontinuation during pregnancy and postpartum psychiatric outcomes in Denmark and NorwayTrinh, Nhung T. H., Munk-Olsen, Trine, Wray, Naomi R., Bergink, Veerle, Nordeng, Hedvig M. E., Lupattelli, Angela and Liu, Xiaoqin (2023). Timing of antidepressant discontinuation during pregnancy and postpartum psychiatric outcomes in Denmark and Norway. JAMA Psychiatry, 80 (5) yoi230003, 441-450. doi: 10.1001/jamapsychiatry.2023.0041 |
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2023 Journal Article An overview of DNA methylation-derived trait score methods and applicationsNabais, Marta F., Gadd, Danni A., Hannon, Eilis, Mill, Jonathan, McRae, Allan F. and Wray, Naomi R. (2023). An overview of DNA methylation-derived trait score methods and applications. Genome Biology, 24 (1) 28, 28. doi: 10.1186/s13059-023-02855-7 |
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2023 Journal Article Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spotsAlbiñana, Clara, Zhu, Zhihong, Borbye-Lorenzen, Nis, Boelt, Sanne Grundvad, Cohen, Arieh S., Skogstrand, Kristin, Wray, Naomi R., Revez, Joana A, Privé, Florian, Petersen, Liselotte V., Bulik, Cynthia M., Plana-Ripoll, Oleguer, Musliner, Katherine L., Agerbo, Esben, Børglum, Anders D., Hougaard, David M., Nordentoft, Merete, Werge, Thomas, Mortensen, Preben Bo, Vilhjálmsson, Bjarni J. and McGrath, John J. (2023). Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots. Nature Communications, 14 (1) 852, 1-16. doi: 10.1038/s41467-023-36392-5 |
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2023 Journal Article Significance tests for R2 of out-of-sample prediction using polygenic scoresMomin, Md. Moksedul, Lee, Soohyun, Wray, Naomi R. and Lee, S. Hong (2023). Significance tests for R2 of out-of-sample prediction using polygenic scores. The American Journal of Human Genetics, 110 (2), 349-358. doi: 10.1016/j.ajhg.2023.01.004 |
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2023 Journal Article Estimation and implications of the genetic architecture of fasting and non-fasting blood glucoseQiao, Zhen, Sidorenko, Julia, Revez, Joana A., Xue, Angli, Lu, Xueling, Pärna, Katri, Snieder, Harold, Visscher, Peter M., Wray, Naomi R., Yengo, Loic and Lifelines Cohort Study (2023). Estimation and implications of the genetic architecture of fasting and non-fasting blood glucose. Nature Communications, 14 (1) 451, 1-11. doi: 10.1038/s41467-023-36013-1 |
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2023 Journal Article mBAT-combo: a more powerful test to detect gene-trait associations from GWAS dataLi, Ang, Liu, Shouye, Bakshi, Andrew, Jiang, Longda, Chen, Wenhan, Zheng, Zhili, Sullivan, Patrick F., Visscher, Peter M., Wray, Naomi R., Yang, Jian and Zeng, Jian (2023). mBAT-combo: a more powerful test to detect gene-trait associations from GWAS data. American Journal of Human Genetics, 110 (1), 30-43. doi: 10.1016/j.ajhg.2022.12.006 |
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2023 Other Outputs Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controlsAnna Freydenzon, Allan F. McRaee, Shyuan Ngo, Naomi R. Wray, Leanne Wallace, Anjali K. Henders, Pamela A. McCombe, Robert D. Henderson and Frederik J. Steyn (2023). Skeletal muscle and blood RNA-seq counts in motor neurone disease cases and controls. The University of Queensland. (Dataset) doi: 10.48610/b722f1f |
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2023 Journal Article Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adultsScott, Jan, Crouse, Jacob J., Medland, Sarah, Byrne, Enda, Iorfino, Frank, Mitchell, Brittany, Gillespie, Nathan A., Martin, Nicholas, Wray, Naomi and Hickie, Ian B. (2023). Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults. Early Intervention in Psychiatry, 18 (6), 397-405. doi: 10.1111/eip.13472 |
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2022 Journal Article Lithium carbonate in amyotrophic lateral sclerosis patients homozygous for the C-allele at SNP rs12608932 in UNC13A: protocol for a confirmatory, randomized, group-sequential, event-driven, double-blind, placebo-controlled trialWillemse, Sean W., Roes, Kit C. B., Van Damme, Philip, Hardiman, Orla, Ingre, Caroline, Povedano, Monica, Wray, Naomi R., Gijzen, Marleen, de Pagter, Mirjam S., Demaegd, Koen C., Janse, Annemarie F. C., Vink, Roel G., Sleutjes, Boudewijn T. H. M., Chiò, Adriano, Corcia, Philippe, Reviers, Evy, Al-Chalabi, Ammar, Kiernan, Matthew C., van den Berg, Leonard H., van Es, Michael A. and van Eijk, Ruben P. A. (2022). Lithium carbonate in amyotrophic lateral sclerosis patients homozygous for the C-allele at SNP rs12608932 in UNC13A: protocol for a confirmatory, randomized, group-sequential, event-driven, double-blind, placebo-controlled trial. Trials, 23 (1) 978. doi: 10.1186/s13063-022-06906-5 |
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2022 Journal Article Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression StudyGomez, Lina, Díaz-Torres, Santiago, Colodro-Conde, Lucía, Garcia-Marin, Luis M., Yap, Chloe X., Byrne, Enda M., Yengo, Loic, Lind, Penelope A., Wray, Naomi R., Medland, Sarah E., Hickie, Ian B., Lupton, Michelle K., Rentería, Miguel E., Martin, Nicholas G. and Campos, Adrian I. (2022). Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study. European Archives of Psychiatry and Clinical Neuroscience, 273 (6), 1359-1368. doi: 10.1007/s00406-022-01527-0 |
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2022 Conference Publication Exploring genetic heterogeneity of depression: scalar and non-scalar SNP effects in the genetics of mild versus severe depressionMartin, Nick, Mitchell, Brittany, Medland, Sarah, Byrne, Enda, Wray, Naomi, Whiteman, David, Olsen, Catherine and Hickie, Ian (2022). Exploring genetic heterogeneity of depression: scalar and non-scalar SNP effects in the genetics of mild versus severe depression. World Congress of Psychiatric Genetics (WCPG), Florence, Italy, 13-17 September 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2022.07.099 |
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2022 Conference Publication PRS prediction beyond family historyByrne, Enda, Wray, Naomi and Middeldorp, Christel M. (2022). PRS prediction beyond family history. World Congress of Psychiatric Genetics (WCPG), Florence, Italy, 13-17 September 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2022.07.019 |
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2022 Conference Publication The shared genetic landscape of blood cell traits and risk of psychiatric and neurological disordersYang, Yuanhao, Zhou, Yuan, Nyholt, Dale, Zhu, Zhihong, Yap, Chloe, Tannenberg, Rudolph, Wu, Yang, Wang, Ying, Taylor, Bruce, Wray, Naomi and Gratten, Jacob (2022). The shared genetic landscape of blood cell traits and risk of psychiatric and neurological disorders. World Congress of Psychiatric Genetics (WCPG), Florence, Italy, 13-17 September 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2022.07.139 |
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2022 Conference Publication Exploring the genome-wide genetic overlap between anxiety and fear disorderster Kuile, Abigail, Mitchell, Brittany, Peel, Alicia, Mundy, Jessica, Hubel, Christopher, Zvrskovec, Johan, Palmos, Alish, Coleman, Jonathan, Davies, Molly, Martin, Nick, Byrne, Enda M., Medland, Sarah E., Wray, Naomi R., Adey, Brett N., Lee, Sang Hyuck, Furtjes, Anna E., Morneau-Vaillancourt, Genevieve, Purves, Kirstin, Skelton, Megan, Hotopf, Matthew, Smith, Daniel J., Veale, David, Armour, Cherie, McIntosh, Andrew, Walters, James T. R., Jones, Ian R., Hirsch, Colette R., Kalsi, Gursharan, Breen, Gerome and Eley, Thalia (2022). Exploring the genome-wide genetic overlap between anxiety and fear disorders. World Congress of Psychiatric Genetics (WCPG), Florence, Italy, 13-17 September 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2022.07.014 |
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2022 Conference Publication Multi-omics analyses of a clinical trial cohort of young people at ultra-high risk of psychosisBarker, Lauren, Byrne, Enda, Amminger, G. Paul, Nelson, Barnaby, Wray, Naomi and McGorry, Patrick D. (2022). Multi-omics analyses of a clinical trial cohort of young people at ultra-high risk of psychosis. World Congress of Psychiatric Genetics (WCPG), Florence, Italy, 13-17 September 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2022.07.249 |
