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2021 Journal Article Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectivenessRoughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609 |
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2021 Journal Article Risk of early-onset depression associated with polygenic liability, parental psychiatric history, and socioeconomic statusAgerbo, Esben, Trabjerg, Betina B., Børglum, Anders D., Schork, Andrew J., Vilhjálmsson, Bjarni J., Pedersen, Carsten B., Hakulinen, Christian, Albiñana, Clara, Hougaard, David M., Grove, Jakob, McGrath, John J., Bybjerg-Grauholm, Jonas, Mors, Ole, Plana-Ripoll, Oleguer, Werge, Thomas, Wray, Naomi R., Mortensen, Preben Bo and Musliner, Katherine L. (2021). Risk of early-onset depression associated with polygenic liability, parental psychiatric history, and socioeconomic status. JAMA Psychiatry, 78 (4), 387-397. doi: 10.1001/jamapsychiatry.2020.4172 |
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2021 Journal Article Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individualsHivert, Valentin, Sidorenko, Julia, Rohart, Florian, Goddard, Michael E., Yang, Jian, Wray, Naomi R., Yengo, Loic and Visscher, Peter M. (2021). Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals. The American Journal of Human Genetics, 108 (5), 786-798. doi: 10.1016/j.ajhg.2021.02.014 |
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2021 Journal Article Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disordersNabais, Marta F., Laws, Simon M., Lin, Tian, Vallerga, Costanza L., Armstrong, Nicola J., Blair, Ian P., Kwok, John B., Mather, Karen A., Mellick, George D., Sachdev, Perminder S., Wallace, Leanne, Henders, Anjali K., Zwamborn, Ramona A. J., Hop, Paul J., Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A. Y., Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kloszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee ... McRae, Allan F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22 (1) 90, 1-30. doi: 10.1186/s13059-021-02275-5 |
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2021 Other Outputs Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in bloodHoward, David M., Pain, Oliver, Arathimos, Ryan, Barbu, Miruna C., Amador, Carmen, Walker, Rosie M., Jermy, Bradley, Adams, Mark J., Deary, Ian J., Porteous, David, Campbell, Archie, Sullivan, Patrick F., Evans, Kathryn L., Arseneault, Louise, Wray, Naomi R., Meaney, Michael, McIntosh, Andrew M. and Lewis, Cathryn M. (2021). Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood. doi: 10.1101/2021.03.10.21253201 |
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2021 Journal Article Association of antihypertensive drug target genes with psychiatric disorders: a Mendelian randomization studyChauquet, Solal, Zhu, Zhihong, O'Donovan, Michael C., Walters, James T. R., Wray, Naomi R. and Shah, Sonia (2021). Association of antihypertensive drug target genes with psychiatric disorders: a Mendelian randomization study. JAMA Psychiatry, 78 (6), 623-631. doi: 10.1001/jamapsychiatry.2021.0005 |
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2021 Journal Article Genome-wide gene expression changes in postpartum depression point towards an altered immune landscapeMehta, Divya, Grewen, Karen, Pearson, Brenda, Wani, Shivangi, Wallace, Leanne, Henders, Anjali K., Binder, Elisabeth B., Frokjaer, Vibe G., Meltzer-Brody, Samantha, Wray, Naomi R. and Stuebe, Alison M. (2021). Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape. Translational Psychiatry, 11 (1) 155, 155. doi: 10.1038/s41398-021-01270-5 |
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2021 Journal Article Widespread signatures of natural selection across human complex traits and functional genomic categoriesZeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2021). Widespread signatures of natural selection across human complex traits and functional genomic categories. Nature Communications, 12 (1) 1164, 1-12. doi: 10.1038/s41467-021-21446-3 |
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2021 Journal Article GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depressionWu, Yeda, Murray, Graham K., Byrne, Enda M., Sidorenko, Julia, Visscher, Peter M. and Wray, Naomi R. (2021). GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Nature Communications, 12 (1) 1146, 1-17. doi: 10.1038/s41467-021-21280-7 |
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2021 Journal Article Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individualsKemper, Kathryn E., Yengo, Loic, Zheng, Zhili, Abdellaoui, Abdel, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R., Yang, Jian and Visscher, Peter M. (2021). Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals. Nature Communications, 12 (1) 1050, 1050. doi: 10.1038/s41467-021-21283-4 |
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2021 Journal Article Analysis of common genetic variation and rare CNVs in the Australian Autism BiobankYap, Chloe X., Alvares, Gail A., Henders, Anjali K., Lin, Tian, Wallace, Leanne, Farrelly, Alaina, McLaren, Tiana, Berry, Jolene, Vinkhuyzen, Anna A. E., Trzaskowski, Maciej, Zeng, Jian, Yang, Yuanhao, Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren, Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Visscher, Peter M., Dawson, Paul A., Dissanayake, Cheryl ... Gratten, Jacob (2021). Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank. Molecular Autism, 12 (1) 12, 12. doi: 10.1186/s13229-020-00407-5 |
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2021 Journal Article Could polygenic risk scores be useful in psychiatry? a reviewMurray, Graham K., Lin, Tian, Austin, Jehannine, McGrath, John J., Hickie, Ian B. and Wray, Naomi R. (2021). Could polygenic risk scores be useful in psychiatry? a review. JAMA Psychiatry, 78 (2), 210-219. doi: 10.1001/jamapsychiatry.2020.3042 |
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2021 Journal Article Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changesXue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2021). Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes. Nature Communications, 12 (1) 988, 988. doi: 10.1038/s41467-021-21294-1 |
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2021 Journal Article Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changesXue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2021). Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes. Nature Communications, 12 (1) 6450, 6450. doi: 10.1038/s41467-020-20237-6 |
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2021 Journal Article Risk in relatives, heritability, SNP-based heritability and genetic correlations in psychiatric disorders: a reviewBaselmans, Bart M.L., Yengo, Loic, van Rheenen, Wouter and Wray, Naomi R. (2021). Risk in relatives, heritability, SNP-based heritability and genetic correlations in psychiatric disorders: a review. Biological Psychiatry, 89 (1), 11-19. doi: 10.1016/j.biopsych.2020.05.034 |
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2021 Journal Article From basic science to clinical application of polygenic risk scores : a primerWray, Naomi R., Lin, Tian, Austin, Jehannine, McGrath, John J., Hickie, Ian B., Murray, Graham K. and Visscher, Peter M. (2021). From basic science to clinical application of polygenic risk scores : a primer. JAMA Psychiatry, 78 (1), 101-109. doi: 10.1001/jamapsychiatry.2020.3049 |
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2021 Journal Article Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic DisordersBlokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972 |
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2021 Journal Article Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioningCrouse, Jacob J., Carpenter, Joanne S., Iorfino, Frank, Lin, Tian, Ho, Nicholas, Byrne, Enda M., Henders, Anjali K., Wallace, Leanne, Hermens, Daniel F., Scott, Elizabeth M., Wray, Naomi R. and Hickie, Ian B. (2021). Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning. BJPsych Open, 7 (2) e58, e58. doi: 10.1192/bjo.2021.14 |
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2021 Conference Publication Association and prediction of phenotypic traits from neuroimaging data using a multi-component mixed model excluding the target vertexCouvy-Duchesne, Baptiste, Zhang, Futao, Kemper, Kathryn E., Sidorenko, Julia, Wray, Naomi R., Visscher, Peter M., Yang, Jian and Colliot, Olivier (2021). Association and prediction of phenotypic traits from neuroimaging data using a multi-component mixed model excluding the target vertex. Conference on Medical Imaging - Image Processing, Online, 15-19 February, 2021. Bellingham, WA, United States: SPIE. doi: 10.1117/12.2581022 |
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2020 Other Outputs Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factorsMullins, Niamh, Kang, Jooeun, Campos, Adrian I, Coleman, Jonathan R I, Edwards, Alexis C, Galfalvy, Hanga, Levey, Daniel F, Lori, Adriana, Shabalin, Andrey, Starnawska, Anna, Su, Mei-Hsin, Watson, Hunna J, Adams, Mark, Awasthi, Swapnil, Gandal, Michael, Hafferty, Jonathan D, Hishimoto, Akitoyo, Kim, Minsoo, Okazaki, Satoshi, Otsuka, Ikuo, Ripke, Stephan, Ware, Erin B, Bergen, Andrew W, Berrettini, Wade H, Bohus, Martin, Brandt, Harry, Chang, Xiao, Chen, Wei J, Chen, Hsi-Chung ... Ruderfer, Douglas M (2020). Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors. doi: 10.1101/2020.12.01.20241281 |
