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2021 Journal Article Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biologyvan Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1 |
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2021 Journal Article Autism-related dietary preferences mediate autism-gut microbiome associationsYap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2021). Autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 184 (24), 5916-5931.e17. doi: 10.1016/j.cell.2021.10.015 |
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2021 Journal Article Understanding genetic risk factors for common side effects of antidepressant medicationsCampos, Adrian I., Mulcahy, Aoibhe, Thorp, Jackson G., Wray, Naomi R., Byrne, Enda M., Lind, Penelope A., Medland, Sarah E., Martin, Nicholas G., Hickie, Ian B. and Rentería, Miguel E. (2021). Understanding genetic risk factors for common side effects of antidepressant medications. Communications Medicine, 1 (1) 45, 1-10. doi: 10.1038/s43856-021-00046-8 |
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2021 Journal Article A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohortsNi, Guiyan, Zeng, Jian, Revez, Joana A., Wang, Ying, Zheng, Zhili, Ge, Tian, Restuadi, Restuadi, Kiewa, Jacqueline, Nyholt, Dale R., Coleman, Jonathan R.I., Smoller, Jordan W., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2021). A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. Biological Psychiatry, 90 (9), 611-620. doi: 10.1016/j.biopsych.2021.04.018 |
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2021 Journal Article The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypesMitchell, Brittany L., Campos, Adrian I., Whiteman, David C., Olsen, Catherine M., Gordon, Scott D., Walker, Adam J., Dean, Olivia M., Berk, Michael, Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G. and Byrne, Enda M. (2021). The Australian Genetics of Depression Study: new risk loci and dissecting heterogeneity between subtypes. Biological Psychiatry, 92 (3), 227-235. doi: 10.1016/j.biopsych.2021.10.021 |
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2021 Journal Article Polygenic burden could explain high rates of affective disorders in a community with restricted founder populationWang, Xiaotong, Lin, Tian, Yengo, Loic, Sidorenko, Julia, Wray, Naomi R. and Levinson, Douglas F. (2021). Polygenic burden could explain high rates of affective disorders in a community with restricted founder population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186 (6), 367-375. doi: 10.1002/ajmg.b.32876 |
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2021 Journal Article Seven short reflections on the notion of schizophreniaMcGrath, John J. and Wray, Naomi R. (2021). Seven short reflections on the notion of schizophrenia. Schizophrenia Research, 242, 96-97. doi: 10.1016/j.schres.2021.09.026 |
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2021 Journal Article MiNDAUS partnership: a roadmap for the cure and management of motor Neurone diseaseVucic, Steve, Wray, Naomi, Henders, Anjali, Henderson, Robert D., Talman, Paul, Mathers, Susan, Bellgard, Matthew, Aoun, Samar, Birks, Carol, Thomas, Gethin, Hansen, Catherine, Thomas, Geoff, Hogden, Anne, Needham, Merrilee, Schultz, David, Soulis, Tina, Sheean, Bec, Milne, Jane, Rowe, Dominic, Zoing, Margie and Kiernan, Matthew C (2021). MiNDAUS partnership: a roadmap for the cure and management of motor Neurone disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1980889 |
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2021 Conference Publication GENOME-WIDE ANALYSIS OF THE ANXIETY DISORDER SPECTRUMter Kuile, Abigail, Davies, Molly, Purves, Kirstin, Coleman, Jonathan, Hubel, Christopher, Kalsi, Gursharan, Mundy, Jessica, Skelton, Megan, Morneau-Vaillancourt, Genevieve, Mundy, Jessica, Zvrskovec, Johan, Armour, Cherie, Jones, Ian R., McIntosh, Andrew M., Walters, James T. R., Smith, Daniel J., Hotopf, Matthew, Medland, Sarah, Byrne, Enda, Wray, Naomi, Thorp, Jackson, Mitchell, Brittany, Martin, Nick, Breen, Gerome and Eley, Thalia (2021). GENOME-WIDE ANALYSIS OF THE ANXIETY DISORDER SPECTRUM. World Congress of Psychiatric Genetics (WCPG), Electr Network, Oct 11-15, 2021. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2021.08.103 |
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2021 Conference Publication BASIC CONCEPTS IN PSYCHIATRIC GENETICSWray, Naomi (2021). BASIC CONCEPTS IN PSYCHIATRIC GENETICS. World Congress of Psychiatric Genetics (WCPG), Electr Network, Oct 11-15, 2021. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2021.07.019 |
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2021 Conference Publication POPULATION BASED AND FUNCTIONAL GENOMIC STUD-IES OF MAJOR DEPRESSIVE DISORDERMcIntosh, Andrew, Caramaschi, Doretta and Wray, Naomi (2021). POPULATION BASED AND FUNCTIONAL GENOMIC STUD-IES OF MAJOR DEPRESSIVE DISORDER. World Congress of Psychiatric Genetics (WCPG), Electr Network, Oct 11-15, 2021. AMSTERDAM: ELSEVIER. doi: 10.1016/j.euroneuro.2021.07.037 |
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2021 Journal Article Discovery and implications of polygenicity of common diseasesVisscher, Peter M., Yengo, Loic, Cox, Nancy J. and Wray, Naomi R. (2021). Discovery and implications of polygenicity of common diseases. Science, 373 (6562), 1468-1473. doi: 10.1126/science.abi8206 |
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2021 Journal Article Investigating shared genetic basis across tourette syndrome and comorbid neurodevelopmental disorders along the impulsivity-compulsivity spectrumYang, Zhiyu, Wu, Hanrui, Lee, Phil H., Tsetsos, Fotis, Davis, Lea K., Yu, Dongmei, Lee, Sang Hong, Dalsgaard, Søren, Haavik, Jan, Barta, Csaba, Zayats, Tetyana, Eapen, Valsamma, Wray, Naomi R., Devlin, Bernie, Daly, Mark, Neale, Benjamin, Børglum, Anders D., Crowley, James J., Scharf, Jeremiah, Mathews, Carol A., Faraone, Stephen V., Franke, Barbara, Mattheisen, Manuel, Smoller, Jordan W. and Paschou, Peristera (2021). Investigating shared genetic basis across tourette syndrome and comorbid neurodevelopmental disorders along the impulsivity-compulsivity spectrum. Biological Psychiatry, 90 (5), 317-327. doi: 10.1016/j.biopsych.2020.12.028 |
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2021 Journal Article Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (vol 25, pg 1430, 2020)Coleman, Jonathan R. I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A. S., Rayner, Christopher, Choi, Shing Wan, Hubel, Christopher, Gaspar, Helena A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O'Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C. and Breen, Gerome (2021). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (vol 25, pg 1430, 2020). Molecular Psychiatry, 26 (9), 5465-5465. doi: 10.1038/s41380-020-0779-4 |
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2021 Journal Article Genomic and phenotypic insights from an atlas of genetic effects on DNA methylationMin, Josine L., Hemani, Gibran, Hannon, Eilis, Dekkers, Koen F., Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J., Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D., Richardson, Tom G., Klughammer, Johanna, Iotchkova, Valentina, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, McArdle, Wendy L., Ho, Karen M., Kumar, Ashish, Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Kazmi, Nabila, Mason, Dan, McRae, Allan F., Corcoran, David L., Sugden, Karen ... BIOS Consortium (2021). Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53 (9), 1311-1321. doi: 10.1038/s41588-021-00923-x |
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2021 Journal Article Polygenic risk scores derived from varying definitions of depression and risk of depressionMitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988 |
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2021 Journal Article Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibilityvan Blokland, Irene V., Lanting, Pauline, Ori, Anil P.S., Vonk, Judith M., Warmerdam, Robert C.A., Herkert, Johanna C., Boulogne, Floranne, Claringbould, Annique, Lopera-Maya, Esteban A., Bartels, Meike, Hottenga, Jouke-Jan, Ganna, Andrea, Karjalainen, Juha, Hayward, Caroline, Fawns-Ritchie, Chloe, Campbell, Archie, Porteous, David, Cirulli, Elizabeth T., Barrett, Kelly M. Schiabor, Riffle, Stephen, Bolze, Alexandre, White, Simon, Tanudjaja, Francisco, Wang, Xueqing, Ramirez, Jimmy M., Lim, Yan Wei, Lu, James T., Washington, Nicole L., de Geus, Eco J. C. ... Yengo, Loic (2021). Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility. PLoS One, 16 (8) e0255402, 1-18. doi: 10.1371/journal.pone.0255402 |
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2021 Journal Article Genetic association study of childhood aggression across raters, instruments, and ageIp, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., St Pourcain, Beate, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Colodro-Conde, Lucía, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Day, Felix R., Hottenga, Jouke-Jan ... Boomsma, Dorret I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11 (1) 413, 413. doi: 10.1038/s41398-021-01480-x |
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2021 Journal Article Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtypeCampos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491 |
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2021 Journal Article Genomic partitioning of inbreeding depression in humansYengo, Loic, Yang, Jian, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2021). Genomic partitioning of inbreeding depression in humans. American Journal of Human Genetics, 108 (8), 1488-1501. doi: 10.1016/j.ajhg.2021.06.005 |
