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2019 Journal Article Improved polygenic prediction by Bayesian multiple regression on summary statisticsLloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tõnu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. Nature Communications, 10 (1) 5086, 1-10. doi: 10.1038/s41467-019-12653-0 |
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2019 Journal Article Bipolar multiplex families have an increased burden of common risk variants for psychiatric disordersAndlauer, Till F. M., Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C., Treutlein, Jens, Witt, Stephanie H., Cichon, Sven, Kogevinas, Manolis, Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry, 26 (4), 1286-1298. doi: 10.1038/s41380-019-0558-2 |
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2019 Journal Article The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controlsColeman, Jonathan R.I., Gaspar, Héléna A., Bryois, Julien, Byrne, Enda M., Forstner, Andreas J., Holmans, Peter A., de Leeuw, Christiaan A., Mattheisen, Manuel, McQuillin, Andrew, Whitehead Pavlides, Jennifer M., Pers, Tune H., Ripke, Stephan, Stahl, Eli A., Steinberg, Stacy, Trubetskoy, Vassily, Trzaskowski, Maciej, Wang, Yunpeng, Abbott, Liam, Abdellaoui, Abdel, Adams, Mark J., Adolfsson, Annelie Nordin, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F.M., Anjorin, Adebayo, Antilla, Verneri ... Breen, Gerome (2019). The genetics of the mood disorder spectrum: Genome-wide association analyses of more than 185,000 cases and 439,000 controls. Biological Psychiatry, 88 (2), 169-184. doi: 10.1016/j.biopsych.2019.10.015 |
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2019 Journal Article Genetic correlates of social stratification in Great BritainAbdellaoui, Abdel, Hugh-Jones, David, Yengo, Loic, Kemper, Kathryn E., Nivard, Michel G., Veul, Laura, Holtz, Yan, Zietsch, Brendan P., Frayling, Timothy M., Wray, Naomi R., Yang, Jian, Verweij, Karin J. H. and Visscher, Peter M. (2019). Genetic correlates of social stratification in Great Britain. Nature Human Behaviour, 3 (12), 1332-1342. doi: 10.1038/s41562-019-0757-5 |
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2019 Journal Article Genetic correlations of polygenic disease traits: from theory to practicevan Rheenen, Wouter, Peyrot, Wouter J., Schork, Andrew J., Lee, S. Hong and Wray, Naomi R. (2019). Genetic correlations of polygenic disease traits: from theory to practice. Nature Reviews Genetics, 20 (10), 567-581. doi: 10.1038/s41576-019-0137-z |
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2019 Journal Article Extreme inbreeding in a European ancestry sample from the contemporary UK populationYengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2019). Extreme inbreeding in a European ancestry sample from the contemporary UK population. Nature Communications, 10 (1) 3719, 3719. doi: 10.1038/s41467-019-11724-6 |
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2019 Journal Article Improved precision of epigenetic clock estimates across tissues and its implication for biological ageingZhang, Qian, Vallerga, Costanza L., Walker, Rosie M., Lin, Tian, Henders, Anjali K., Montgomery, Grant W., He, Ji, Fan, Dongsheng, Fowdar, Javed, Kennedy, Martin, Pitcher, Toni, Pearson, John, Halliday, Glenda, Kwok, John B., Hickie, Ian, Lewis, Simon, Anderson, Tim, Silburn, Peter A., Mellick, George D., Harris, Sarah E., Redmond, Paul, Murray, Alison D., Porteous, David J., Haley, Christopher S., Evans, Kathryn L., McIntosh, Andrew M., Yang, Jian, Gratten, Jacob, Marioni, Riccardo E. ... Visscher, Peter M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11 (1) 54, 54. doi: 10.1186/s13073-019-0667-1 |
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2019 Journal Article Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK BiobankWang, Huanwei, Zhang, Futao, Zeng, Jian, Wu, Yang, Kemper, Kathryn E., Xue, Angli, Zhang, Min, Powell, Joseph E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2019). Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Science Advances, 5 (8) eaaw3538, 1-12. doi: 10.1126/sciadv.aaw3538 |
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2019 Journal Article Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depressionGlanville, Kylie P., Coleman, Jonathan R. I., Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Purves, Kirstin L., Breen, Gerome, Air, Tracy M., Andlauer, Till F. M., Baune, Bernhard T., Binder, Elisabeth B., Blackwood, Douglas H. R., Boomsma, Dorret I., Buttenschøn, Henriette N., Colodro-Conde, Lucía, Dannlowski, Udo, Direk, Nese, Dunn, Erin C., Forstner, Andreas J., de Geus, Eco J. C., Grabe, Hans J., Hamilton, Steven P., Jones, Ian, Jones, Lisa A., Knowles, James A., Kutalik, Zoltán, Levinson, Douglas F., Lewis, Glyn, Lind, Penelope A. ... Børglum, Anders D. (2019). Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated With depression. Biological Psychiatry, 87 (5), 419-430. doi: 10.1016/j.biopsych.2019.06.031 |
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2019 Journal Article GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scoresMullins, Niamh, Bigdeli, Tim B., Børglum, Anders D., Coleman, Jonathan R.I., Demontis, Ditte, Mehta, Divya, Power, Robert A., Ripke, Stephan, Stahl, Eli A., Starnawska, Anna, Anjorin, Adebayo, Corvin, Aiden, Sanders, Alan R., Forstner, Andreas J., Reif, Andreas, Koller, Anna C., Tkowska, Beata Swia, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W.J.H., Pato, Carlos, Zai, Clement, Rujescu, Dan, Hougaard, David M., Quested, Digby, Levinson, Douglas F., Binder, Elisabeth B., Byrne, Enda M., Agerbo, Esben ... Lewis, Cathryn M. (2019). GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores. American Journal of Psychiatry, 176 (8), 651-660. doi: 10.1176/appi.ajp.2019.18080957 |
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2019 Journal Article Assortative mating in autism spectrum disorder: toward an evidence base from DNA data, but not there yetWray, Naomi R. and Yengo, Loic (2019). Assortative mating in autism spectrum disorder: toward an evidence base from DNA data, but not there yet. Biological Psychiatry, 86 (4), 250-252. doi: 10.1016/j.biopsych.2019.06.007 |
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2019 Journal Article Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936. Nature Communications, 10 (1) 3160, 3160. doi: 10.1038/s41467-019-11177-x |
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2019 Journal Article Evaluating the impact of nonrandom mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorderNordsletten, Ashley E., Brander, Gustaf, Larsson, Henrik, Lichtenstein, Paul, Crowley, James J., Sullivan, Patrick F., Wray, Naomi R. and Mataix-Cols, David (2019). Evaluating the impact of nonrandom mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorder. Biological Psychiatry, 87 (3), 253-262. doi: 10.1016/j.biopsych.2019.06.025 |
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2019 Journal Article Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association studyPeriyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G., Nyholt, Dale R., Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B., Wray, Naomi R., Brown, Matthew A., Suetani, Rachel, Giacomotto, Jean ... Mowry, Bryan J. (2019). Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study. JAMA Psychiatry, 76 (10), 1026-1034. doi: 10.1001/jamapsychiatry.2019.1335 |
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2019 Journal Article The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the publicvan der Spek, Rick A. A., van Rheenen, Wouter, Pulit, Sara L., Kenna, Kevin P., van den Berg, Leonard H., Veldink, Jan H., Project MinE ALS Sequencing Consortium and Wray, Naomi R. (2019). The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20 (5-6), 432-440. doi: 10.1080/21678421.2019.1606244 |
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2019 Journal Article Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selectionPardiñas, Antonio F., Holmans, Peter, Pocklington, Andrew J., Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E., Bishop, Sophie, Cameron, Darren, Hamshere, Marian L., Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H., McCarroll, Steven A., Baune, Bernhard T., Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C., Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M., Plomin, Robert, Porteous, David J., Wray, Naomi R., Caballero, Armando ... Walters, James T. R. (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 51 (7), 1193-1193. doi: 10.1038/s41588-019-0450-7 |
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2019 Journal Article Students’, colleagues’ and research partners’ experience about work and accomplishments from collaborating with Robin ThompsonHickey, John, Hill, William G., Blasco, Agustin, Cameron, Neil, Cullis, Brian, McGuirk, Brian, Mäntysaari, Esa, Ruane, John, Simm, Geoff, Veerkamp, Roel, Visscher, Peter M. and Wray, Naomi R. (2019). Students’, colleagues’ and research partners’ experience about work and accomplishments from collaborating with Robin Thompson. Journal of Animal Breeding and Genetics, 136 (4), 301-309. doi: 10.1111/jbg.12418 |
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2019 Journal Article “Arte et Labore” - a Blackburn Rovers fan's legacy in human complex trait geneticsVisscher, Peter M., Wray, Naomi R. and Haley, Chris S. (2019). “Arte et Labore” - a Blackburn Rovers fan's legacy in human complex trait genetics. Journal of Animal Breeding and Genetics, 136 (4), 273-278. doi: 10.1111/jbg.12384 |
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2019 Journal Article Correction: GWAS on family history of Alzheimer’s diseaseMarioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2019). Correction: GWAS on family history of Alzheimer’s disease. Translational Psychiatry, 9 (1) 161, 161. doi: 10.1038/s41398-019-0498-2 |
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2019 Journal Article Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (Nature Genetics, (2019), 51, 4, (659-674), 10.1038/s41588-019-0364-4)Huckins, Laura M., Dobbyn, Amanda, Ruderfer, Douglas M., Hoffman, Gabriel, Wang, Weiqing, Pardiñas, Antonio F., Rajagopal, Veera M., Als, Thomas D., T. Nguyen, Hoang, Girdhar, Kiran, Boocock, James, Roussos, Panos, Fromer, Menachem, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R., Purcell, Shaun, Johnson, Jessica S., Shah, Hardik R., Klein, Lambertus L., Dang, Kristen K., Logsdon, Benjamin A., Mahajan, Milind C., Mangravite, Lara M., Toyoshiba, Hiroyoshi, Gur, Raquel E., Hahn, Chang-Gyu, Schadt, Eric, Lewis, David A. ... Stahl, Eli A. (2019). Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (Nature Genetics, (2019), 51, 4, (659-674), 10.1038/s41588-019-0364-4). Nature Genetics, 51 (6), 1068-1068. doi: 10.1038/s41588-019-0435-6 |
