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2019

Conference Publication

Examining the shared genetics between educational attainment and depression: results from the Australian Genetics of Depression Study

Mitchell, Brittany, Renteria, Miguel E., Byrne, Enda, Conde, Lucia Colodro, Han, Xikun, Medland, Sarah E., Wray, Naomi and Martin, Nick (2019). Examining the shared genetics between educational attainment and depression: results from the Australian Genetics of Depression Study. 27th World Congress of Psychiatric Genetics, Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.172

Examining the shared genetics between educational attainment and depression: results from the Australian Genetics of Depression Study

2019

Conference Publication

Uncovering the genetic architecture of major depression and its phenome-wide effects

McIntosh, Andrew, Shen, Xueyi, Howard, David, Adams, Mark, Clarke, Toni, Whalley, Heather, Coleman, Jonathan, Wray, Naomi, Lewis, Cathryn, Sullivan, Patrick and Breen, Gerome (2019). Uncovering the genetic architecture of major depression and its phenome-wide effects. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.108

Uncovering the genetic architecture of major depression and its phenome-wide effects

2019

Conference Publication

Identification of genetic risk factors for postpartum depression

Guintivano, Jerry, Byrne, Enda, Watson, Hunna, Wray, Naomi, Meltzer-Brody, Samantha and Sullivan, Patrick (2019). Identification of genetic risk factors for postpartum depression. 27th World Congress of Psychiatric Genetics, Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.194

Identification of genetic risk factors for postpartum depression

2019

Conference Publication

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

2019

Conference Publication

Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorder

Crowley, James, Nordsletten, Ashley, Brander, Gustaf, Sullivan, Patrick, Wray, Naomi, Larsson, Henrik, Lichtenstein, Paul and Mataix-Cols, David (2019). Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorder. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.197

Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorder

2019

Conference Publication

The omnigenic architecture of human complex traits

Pritchard, Jonathan and Wray, Naomi (2019). The omnigenic architecture of human complex traits. 26th World Congress of Psychiatric Genetics, Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.07.093

The omnigenic architecture of human complex traits

2019

Conference Publication

Validating GWA associations in psychiatric disorders with functional genomic data

Trzaskowski, Maciej, Byrne, Enda, Yang, Jian and Wray, Naomi (2019). Validating GWA associations in psychiatric disorders with functional genomic data. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2017.08.019

Validating GWA associations in psychiatric disorders with functional genomic data

2019

Conference Publication

Genetics of depression

Flint, Jonathan, McIntosh, Andrew and Wray, Naomi (2019). Genetics of depression. 27th World Congress of Psychiatric Genetics, Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.106

Genetics of depression

2019

Conference Publication

Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits

Couvy-Duchesne, Baptiste, Strike, Lachlan, Zhang, Futao, Wray, Naomi, Wright, Margaret, Visscher, Peter and Yang, Jian (2019). Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.140

Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits

2019

Conference Publication

What next for the PCG? What next for psychiatric genetics?

Sullivan, Patrick and Wray, Naomi (2019). What next for the PCG? What next for psychiatric genetics?. 27th World Congress of Psychiatric Genetics, Los Angeles, California, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.008

What next for the PCG? What next for psychiatric genetics?

2019

Conference Publication

Assessing clinical, demographic and genetic risk factors for treatment attributed suicidality in > 20,000 Australian adults on antidepressants

Campos, Adrian, Renteria, Miguel E., Byrne, Enda, Medland, Sarah E., Wray, Naomi, Hickie, Ian B. and Martin, Nick (2019). Assessing clinical, demographic and genetic risk factors for treatment attributed suicidality in > 20,000 Australian adults on antidepressants. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.212

Assessing clinical, demographic and genetic risk factors for treatment attributed suicidality in > 20,000 Australian adults on antidepressants

2019

Journal Article

A polygenic resilience score moderates the genetic risk for schizophrenia

Hess, Jonathan L., Tylee, Daniel S., Mattheisen, Manuel, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Andreassen, Ole A, Arranz, Maria J, Bacanu, Silviu A, Bakker, Steven, Band, Gavin, Barroso, Ines, Begemann, Martin, Bellenguez, Céline, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Bramon, Elvira, Brown, Matthew A ... Glatt, Stephen J. (2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry, 26 (3), 800-815. doi: 10.1038/s41380-019-0463-8

A polygenic resilience score moderates the genetic risk for schizophrenia

2019

Journal Article

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

Foo, Jerome C., Streit, Fabian, Frank, Josef, Witt, Stephanie H., Treutlein, Jens, Baune, Bernhard T., Moebus, Susanne, Joeckel, Karl-Heinz, Forstner, Andreas J., Noethen, Markus M., Rietschel, Marcella, Sartorius, Alexander, Kranaster, Laura, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R. ... Sullivan, Patrick F. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (1), 35-45. doi: 10.1002/ajmg.b.32700

Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

2019

Conference Publication

Genetic risk scores and postpartum psychiatric disorders

Bauer, Anna, Liu, Xiaoqin, Byrne, Enda, Sullivan, Patrick, Wray, Naomi, Agerbo, Esben, Nyegaard, Mette, Ingstrup, Katja, Johannsen, Benedicte, Maegbaek, Merete, Wang, Yunpeng, Nordentoft, Merete, Mortensen, Preben Bo, Munk-Olsen, Trine and Meltzer-Brody, Samantha (2019). Genetic risk scores and postpartum psychiatric disorders. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.048

Genetic risk scores and postpartum psychiatric disorders

2019

Conference Publication

Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD

Hammerschlag, Anke, Byrne, Enda, Bartels, Meike, Wray, Naomi and Middeldorp, Christel M. (2019). Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.063

Integrative analysis of genome-wide association study results of attention-deficit/hyperactivity disorder (ADHD) and human fetal brain methylation data reveals novel genes associated with ADHD

2019

Conference Publication

Absolute risk of major depression associated with the polygenic risk score for depression, parental socio-economic status and history of mental disorders: a Danish population-based study

Agerbo, Esben, Trabjerg, Betina, Schork, Andrew, Vilhjalmsson, Bjarni, Climent, Clara Albinana, Wray, Naomi, Werge, Thomas, Borglum, Anders, Mors, Ole, Nordentoft, Merete, Hougaard, David, McGrath, John, Mortensen, Preben Bo and Musliner, Katherine (2019). Absolute risk of major depression associated with the polygenic risk score for depression, parental socio-economic status and history of mental disorders: a Danish population-based study. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.191

Absolute risk of major depression associated with the polygenic risk score for depression, parental socio-economic status and history of mental disorders: a Danish population-based study

2018

Journal Article

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Stevenson, Anna J., McCartney, Daniel L., Harris, Sarah E., Taylor, Adele M., Redmond, Paul, Starr, John M., Zhang, Qian, McRae, Allan F., Wray, Naomi R., Spires-Jones, Tara L., McColl, Barry W., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2018). Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing. Clinical Epigenetics, 10 (1) 159, 159. doi: 10.1186/s13148-018-0585-x

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

2018

Journal Article

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

Yap, Chloe X., Sidorenko, Julia, Wu, Yang, Kemper, Kathryn E., Yang, Jian, Wray, Naomi R., Robinson, Matthew R. and Visscher, Peter M. (2018). Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. Nature Communications, 9 (1) 5407, 5407. doi: 10.1038/s41467-018-07862-y

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

2018

Other Outputs

Genetic analyses of medication-use and implications for precision medicine

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2018). Genetic analyses of medication-use and implications for precision medicine. doi: 10.1101/501049

Genetic analyses of medication-use and implications for precision medicine

2018

Journal Article

Identification of 55,000 replicated DNA methylation QTL

McRae, Allan F., Marioni, Riccardo E., Shah, Sonia, Yang, Jian, Powell, Joseph E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Bowdler, Lisa, Painter, Jodie N., Murphy, Lee, Martin, Nicholas G., Starr, John M., Wray, Naomi R., Deary, Ian J., Visscher, Peter M. and Montgomery, Grant W. (2018). Identification of 55,000 replicated DNA methylation QTL. Scientific Reports, 8 (1) 17605, 17605. doi: 10.1038/s41598-018-35871-w

Identification of 55,000 replicated DNA methylation QTL