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2019 Journal Article Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortiumPolimanti, Renato, Peterson, Roseann E., Ong, Jue-Sheng, MacGregor, Stuart, Edwards, Alexis C., Clarke, Toni-Kim, Frank, Josef, Gerring, Zachary, Gillespie, Nathan A., Lind, Penelope A., Maes, Hermine H., Martin, Nicholas G., Mbarek, Hamdi, Medland, Sarah E., Streit, Fabian, Agrawal, Arpana, Edenberg, Howard J., Kendler, Kenneth S., Lewis, Cathryn M., Sullivan, Patrick F., Wray, Naomi R., Gelernter, Joel and Derks, Eske M. (2019). Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortium. Psychological Medicine, 49 (07), 1-9. doi: 10.1017/S0033291719000667 |
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2019 Journal Article Genome-wide association study identifies 30 loci associated with bipolar disorderStahl, Eli A., Breen, Gerome, Forstner, Andreas J., McQuillin, Andrew, Ripke, Stephan, Trubetskoy, Vassily, Mattheisen, Manuel, Wang, Yunpeng, Coleman, Jonathan R. I., Gaspar, Héléna A., de Leeuw, Christiaan A., Steinberg, Stacy, Pavlides, Jennifer M. Whitehead, Trzaskowski, Maciej, Byrne, Enda M., Pers, Tune H., Holmans, Peter A., Richards, Alexander L., Abbott, Liam, Agerbo, Esben, Akil, Huda, Albani, Diego, Alliey-Rodriguez, Ney, Als, Thomas D., Anjorin, Adebayo, Antilla, Verneri, Awasthi, Swapnil, Badner, Judith A., Bækvad-Hansen, Marie ... Sklar, Pamela (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51 (5), 793-803. doi: 10.1038/s41588-019-0397-8 |
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2019 Journal Article Genome-wide association study of medication-use and associated disease in the UK BiobankWu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2019). Genome-wide association study of medication-use and associated disease in the UK Biobank. Nature Communications, 10 (1) 1891, 1891. doi: 10.1038/s41467-019-09572-5 |
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2019 Journal Article Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritabilityReynolds, Regina H., Botia, Juan, Nalls, Mike A., Hardy, John, Taliun, Sarah A. Gagliano, Ryten, Mina, Noyce, Alastair J., Nicolas, Aude, Cookson, Mark R., Bandres-Ciga, Sara, Gibbs, J. Raphael, Hernandez, Dena G., Singleton, Andrew B., Reed, Xylena, Leonard, Hampton, Blauwendraat, Cornelis, Faghri, Faraz, Bras, Jose, Guerreiro, Rita, Tucci, Arianna, Kia, Demis A., Houlden, Henry, Plun-Favreau, Helene, Mok, Kin Y., Wood, Nicholas W., Lovering, Ruth, R'Bibo, Lea, Rizig, Mie, Chelban, Viorica ... Pearson, John (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability. Npj Parkinsons Disease, 5 (1) 6, 6. doi: 10.1038/s41531-019-0076-6 |
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2019 Journal Article Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophreniaHarold, Denise, Connolly, Siobhan, Riley, Brien P., Kendler, Kenneth S., McCarthy, Shane E., McCombie, William R., Richards, Alex, Owen, Michael J., O'Donovan, Michael C., Walters, James, Donnelly, Peter, Bates, Lesley, Barroso, Ines, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C. ... Morris, Derek W. (2019). Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 180 (3), 223-231. doi: 10.1002/ajmg.b.32716 |
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2019 Journal Article Complex trait prediction from genome data: contrasting EBV in livestock to PRS in humans: genomic predictionWray, Naomi R., Kemper, Kathryn E., Hayes, Benjamin J., Goddard, Michael E. and Visscher, Peter M. (2019). Complex trait prediction from genome data: contrasting EBV in livestock to PRS in humans: genomic prediction. Genetics, 211 (4), 1131-1141. doi: 10.1534/genetics.119.301859 |
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2019 Journal Article Assessment of bidirectional relationships between physical activity and depression among adults A 2-Sample mendelian randomization studyChoi, Karmel W., Chen, Chia-Yen, Stein, Murray B., Klimentidis, Yann C., Wang, Min-Jung, Koenen, Karestan C., Smoller, Jordan W., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, TracyM., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Hvarregaard, Jane ... Sullivan, Patrick F. (2019). Assessment of bidirectional relationships between physical activity and depression among adults A 2-Sample mendelian randomization study. JAMA Psychiatry, 76 (4), 399-408. doi: 10.1001/jamapsychiatry.2018.4175 |
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2019 Journal Article Gene expression imputation across multiple brain regions provides insights into schizophrenia riskHuckins, Laura M., Dobbyn, Amanda, Ruderfer, Douglas M., Hoffman, Gabriel, Wang, Weiqing, Pardiñas, Antonio F., Rajagopal, Veera M., Als, Thomas D., T. Nguyen, Hoang, Girdhar, Kiran, Boocock, James, Roussos, Panos, Fromer, Menachem, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R., Purcell, Shaun, Johnson, Jessica S., Shah, Hardik R., Klein, Lambertus L., Dang, Kristen K., Logsdon, Benjamin A., Mahajan, Milind C., Mangravite, Lara M., Toyoshiba, Hiroyoshi, Gur, Raquel E., Hahn, Chang-Gyu, Schadt, Eric, Lewis, David A. ... Stahl, Eli A. (2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51 (4), 659-674. doi: 10.1038/s41588-019-0364-4 |
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2019 Journal Article Cumulative influence of parity-related genomic changes in multiple sclerosisMehta, Divya, Wani, Shivangi, Wallace, Leanne, Henders, Anjali K., Wray, Naomi R. and McCombe, Pamela A. (2019). Cumulative influence of parity-related genomic changes in multiple sclerosis. Journal of Neuroimmunology, 328, 38-49. doi: 10.1016/j.jneuroim.2018.12.004 |
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2019 Journal Article Identification of common genetic risk variants for autism spectrum disorderGrove, Jakob, Ripke, Stephan, Als, Thomas D., Mattheisen, Manuel, Walters, Raymond K., Won, Hyejung, Pallesen, Jonatan, Agerbo, Esben, Andreassen, Ole A., Anney, Richard, Awashti, Swapnil, Belliveau, Rich, Bettella, Francesco, Buxbaum, Joseph D., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Christensen, Jane H., Churchhouse, Claire, Dellenvall, Karin, Demontis, Ditte, De Rubeis, Silvia, Devlin, Bernie, Djurovic, Srdjan, Dumont, Ashley L., Goldstein, Jacqueline I., Hansen, Christine S., Hauberg, Mads Engel ... Børglum, Anders D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51 (3), 431-444. doi: 10.1038/s41588-019-0344-8 |
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2019 Journal Article Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regionsHoward, David M., Adams, Mark J., Clarke, Toni-Kim, Hafferty, Jonathan D., Gibson, Jude, Shirali, Masoud, Coleman, Jonathan R. I., Hagenaars, Saskia P., Ward, Joey, Wigmore, Eleanor M., Alloza, Clara, Shen, Xueyi, Barbu, Miruna C., Xu, Eileen Y., Whalley, Heather C., Marioni, Riccardo E., Porteous, David J., Davies, Gail, Deary, Ian J., Hemani, Gibran, Berger, Klaus, Teismann, Henning, Rawal, Rajesh, Arolt, Volker, Baune, Bernhard T., Dannlowski, Udo, Domschke, Katharina, Tian, Chao, Hinds, David A. ... McIntosh, Andrew M. (2019). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nature Neuroscience, 22 (3), 343-352. doi: 10.1038/s41593-018-0326-7 |
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2019 Journal Article Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation ScotlandArnau-Soler, Aleix, Macdonald-Dunlop, Erin, Adams, Mark J., Clarke, Toni-Kim, MacIntyre, Donald J., Milburn, Keith, Navrady, Lauren, Hayward, Caroline, McIntosh, Andrew M., Thomson, Pippa A., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R., Bryois, Julien, Buttenscon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland. Translational Psychiatry, 9 (1) 14. doi: 10.1038/s41398-018-0360-y |
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2019 Journal Article Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorderTrzaskowski, Maciej, Mehta, Divya, Peyrot, Wouter J., Hawkes, David, Davies, Daniel, Howard, David M., Kemper, Kathryn E., Sidorenko, Julia, Maier, Robert, Ripke, Stephan, Mattheisen, Manuel, Baune, Bernhard T., Grabe, Hans J., Heath, Andrew C., Jones, Lisa, Jones, Ian, Madden, Pamela A.F., McIntosh, Andrew M., Breen, Gerome, Lewis, Cathryn M., Børglum, Anders D., Sullivan, Patrick F., Martin, Nicholas G., Kendler, Kenneth S., Levinson, Douglas F. and Wray, Naomi R. (2019). Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (6), 439-447. doi: 10.1002/ajmg.b.32713 |
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2019 Journal Article Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndromeNiarchou, Maria, Chawner, Samuel J. R. A., Fiksinski, Ania, Vorstman, Jacob A. S., Maeder, Johanna, Schneider, Maude, Eliez, Stephan, Armando, Marco, Pontillo, Maria, Vicari, Stefano, McDonald-McGinn, Donna M., Emanuel, Beverly S., Zackai, Elaine H., Bearden, Carrie E., Shashi, Vandana, Hooper, Stephen R., Owen, Michael J., Gur, Raquel E., Wray, Naomi R., van den Bree, Marianne B. M. and Thapar, Anita (2019). Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndrome. Schizophrenia Research, 204, 320-325. doi: 10.1016/j.schres.2018.07.044 |
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2019 Journal Article A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopmentSchork, Andrew J., Won, Hyejung, Appadurai, Vivek, Nudel, Ron, Gandal, Mike, Delaneau, Olivier, Revsbech Christiansen, Malene, Hougaard, David M., Bækved-Hansen, Marie, Bybjerg-Grauholm, Jonas, Giørtz Pedersen, Marianne, Agerbo, Esben, Bøcker Pedersen, Carsten, Neale, Benjamin M., Daly, Mark J., Wray, Naomi R., Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Bo Mortensen, Preben, Buil, Alfonso, Thompson, Wesley K., Geschwind, Daniel H. and Werge, Thomas (2019). A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment. Nature Neuroscience, 22 (3), 353-361. doi: 10.1038/s41593-018-0320-0 |
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2019 Conference Publication Identification of genetic risk factors for postpartum depressionGuintivano, Jerry, Byrne, Enda, Watson, Hunna, Wray, Naomi, Meltzer-Brody, Samantha and Sullivan, Patrick (2019). Identification of genetic risk factors for postpartum depression. 27th World Congress of Psychiatric Genetics, Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.194 |
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2019 Conference Publication Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothersGratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167 |
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2019 Conference Publication Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorderCrowley, James, Nordsletten, Ashley, Brander, Gustaf, Sullivan, Patrick, Wray, Naomi, Larsson, Henrik, Lichtenstein, Paul and Mataix-Cols, David (2019). Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorder. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.197 |
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2019 Conference Publication The omnigenic architecture of human complex traitsPritchard, Jonathan and Wray, Naomi (2019). The omnigenic architecture of human complex traits. 26th World Congress of Psychiatric Genetics, Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.07.093 |
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2019 Conference Publication Validating GWA associations in psychiatric disorders with functional genomic dataTrzaskowski, Maciej, Byrne, Enda, Yang, Jian and Wray, Naomi (2019). Validating GWA associations in psychiatric disorders with functional genomic data. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2017.08.019 |
