2019 Other Outputs Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disordersByrne, Enda M, Zhu, Zhihong, Qi, Ting, Skene, Nathan G, Bryois, Julien, Pardinas, Antonio F, Stahl, Eli, Smoller, Jordan W, Rietschel, Marcella, Consortium, Bipolar Working Group of the Psychiatric Genomics, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Owen, Michael J, Walters, James T.R., O’Donovan, Michael C, McGrath, John G, Hjerling-Leffler, Jens, Sullivan, Patrick F, Goddard, Michael E, Visscher, Peter M, Yang, Jian and Wray, Naomi R (2019). Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders. doi: 10.1101/592899 |
2019 Journal Article Cumulative influence of parity-related genomic changes in multiple sclerosisMehta, Divya, Wani, Shivangi, Wallace, Leanne, Henders, Anjali K., Wray, Naomi R. and McCombe, Pamela A. (2019). Cumulative influence of parity-related genomic changes in multiple sclerosis. Journal of Neuroimmunology, 328, 38-49. doi: 10.1016/j.jneuroim.2018.12.004 |
2019 Journal Article Identification of common genetic risk variants for autism spectrum disorderGrove, Jakob, Ripke, Stephan, Als, Thomas D., Mattheisen, Manuel, Walters, Raymond K., Won, Hyejung, Pallesen, Jonatan, Agerbo, Esben, Andreassen, Ole A., Anney, Richard, Awashti, Swapnil, Belliveau, Rich, Bettella, Francesco, Buxbaum, Joseph D., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Cerrato, Felecia, Chambert, Kimberly, Christensen, Jane H., Churchhouse, Claire, Dellenvall, Karin, Demontis, Ditte, De Rubeis, Silvia, Devlin, Bernie, Djurovic, Srdjan, Dumont, Ashley L., Goldstein, Jacqueline I., Hansen, Christine S., Hauberg, Mads Engel ... Børglum, Anders D. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51 (3), 431-444. doi: 10.1038/s41588-019-0344-8 |
2019 Other Outputs Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940 |
2019 Journal Article Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regionsHoward, David M., Adams, Mark J., Clarke, Toni-Kim, Hafferty, Jonathan D., Gibson, Jude, Shirali, Masoud, Coleman, Jonathan R. I., Hagenaars, Saskia P., Ward, Joey, Wigmore, Eleanor M., Alloza, Clara, Shen, Xueyi, Barbu, Miruna C., Xu, Eileen Y., Whalley, Heather C., Marioni, Riccardo E., Porteous, David J., Davies, Gail, Deary, Ian J., Hemani, Gibran, Berger, Klaus, Teismann, Henning, Rawal, Rajesh, Arolt, Volker, Baune, Bernhard T., Dannlowski, Udo, Domschke, Katharina, Tian, Chao, Hinds, David A. ... McIntosh, Andrew M. (2019). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nature Neuroscience, 22 (3), 343-352. doi: 10.1038/s41593-018-0326-7 |
2019 Journal Article Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation ScotlandArnau-Soler, Aleix, Macdonald-Dunlop, Erin, Adams, Mark J., Clarke, Toni-Kim, MacIntyre, Donald J., Milburn, Keith, Navrady, Lauren, Hayward, Caroline, McIntosh, Andrew M., Thomson, Pippa A., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R., Bryois, Julien, Buttenscon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland. Translational Psychiatry, 9 (1) 14. doi: 10.1038/s41398-018-0360-y |
2019 Journal Article Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorderTrzaskowski, Maciej, Mehta, Divya, Peyrot, Wouter J., Hawkes, David, Davies, Daniel, Howard, David M., Kemper, Kathryn E., Sidorenko, Julia, Maier, Robert, Ripke, Stephan, Mattheisen, Manuel, Baune, Bernhard T., Grabe, Hans J., Heath, Andrew C., Jones, Lisa, Jones, Ian, Madden, Pamela A.F., McIntosh, Andrew M., Breen, Gerome, Lewis, Cathryn M., Børglum, Anders D., Sullivan, Patrick F., Martin, Nicholas G., Kendler, Kenneth S., Levinson, Douglas F. and Wray, Naomi R. (2019). Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (6), 439-447. doi: 10.1002/ajmg.b.32713 |
2019 Journal Article Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndromeNiarchou, Maria, Chawner, Samuel J. R. A., Fiksinski, Ania, Vorstman, Jacob A. S., Maeder, Johanna, Schneider, Maude, Eliez, Stephan, Armando, Marco, Pontillo, Maria, Vicari, Stefano, McDonald-McGinn, Donna M., Emanuel, Beverly S., Zackai, Elaine H., Bearden, Carrie E., Shashi, Vandana, Hooper, Stephen R., Owen, Michael J., Gur, Raquel E., Wray, Naomi R., van den Bree, Marianne B. M. and Thapar, Anita (2019). Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndrome. Schizophrenia Research, 204, 320-325. doi: 10.1016/j.schres.2018.07.044 |
2019 Journal Article A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopmentSchork, Andrew J., Won, Hyejung, Appadurai, Vivek, Nudel, Ron, Gandal, Mike, Delaneau, Olivier, Revsbech Christiansen, Malene, Hougaard, David M., Bækved-Hansen, Marie, Bybjerg-Grauholm, Jonas, Giørtz Pedersen, Marianne, Agerbo, Esben, Bøcker Pedersen, Carsten, Neale, Benjamin M., Daly, Mark J., Wray, Naomi R., Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Bo Mortensen, Preben, Buil, Alfonso, Thompson, Wesley K., Geschwind, Daniel H. and Werge, Thomas (2019). A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment. Nature Neuroscience, 22 (3), 353-361. doi: 10.1038/s41593-018-0320-0 |
2019 Other Outputs Improved polygenic prediction by Bayesian multiple regression on summary statisticsLloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tonu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. doi: 10.1101/522961 |
2019 Conference Publication Identification of genetic risk factors for postpartum depressionGuintivano, Jerry, Byrne, Enda, Watson, Hunna, Wray, Naomi, Meltzer-Brody, Samantha and Sullivan, Patrick (2019). Identification of genetic risk factors for postpartum depression. 27th World Congress of Psychiatric Genetics, Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.194 |
2019 Conference Publication Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothersGratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167 |
2019 Conference Publication Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorderCrowley, James, Nordsletten, Ashley, Brander, Gustaf, Sullivan, Patrick, Wray, Naomi, Larsson, Henrik, Lichtenstein, Paul and Mataix-Cols, David (2019). Evaluating the impact of non-random mating: psychiatric outcomes among the offspring of pairs diagnosed with schizophrenia and bipolar disorder. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.197 |
2019 Conference Publication The omnigenic architecture of human complex traitsPritchard, Jonathan and Wray, Naomi (2019). The omnigenic architecture of human complex traits. 26th World Congress of Psychiatric Genetics, Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.07.093 |
2019 Conference Publication Validating GWA associations in psychiatric disorders with functional genomic dataTrzaskowski, Maciej, Byrne, Enda, Yang, Jian and Wray, Naomi (2019). Validating GWA associations in psychiatric disorders with functional genomic data. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2017.08.019 |
2019 Conference Publication Genetics of depressionFlint, Jonathan, McIntosh, Andrew and Wray, Naomi (2019). Genetics of depression. 27th World Congress of Psychiatric Genetics, Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.106 |
2019 Conference Publication Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traitsCouvy-Duchesne, Baptiste, Strike, Lachlan, Zhang, Futao, Wray, Naomi, Wright, Margaret, Visscher, Peter and Yang, Jian (2019). Inter-individual cortical and subcortical similarity is associated with differences in psychiatric, cognition and socio-economic traits. 25th World Congress of Psychiatric Genetics (WCPG), Orlando, FL, United States, 13-17 October 2017. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2017.08.140 |
2019 Conference Publication What next for the PCG? What next for psychiatric genetics?Sullivan, Patrick and Wray, Naomi (2019). What next for the PCG? What next for psychiatric genetics?. 27th World Congress of Psychiatric Genetics, Los Angeles, California, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.008 |
2019 Conference Publication Assessing clinical, demographic and genetic risk factors for treatment attributed suicidality in > 20,000 Australian adults on antidepressantsCampos, Adrian, Renteria, Miguel E., Byrne, Enda, Medland, Sarah E., Wray, Naomi, Hickie, Ian B. and Martin, Nick (2019). Assessing clinical, demographic and genetic risk factors for treatment attributed suicidality in > 20,000 Australian adults on antidepressants. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, United States, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.212 |
2019 Journal Article Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapyFoo, Jerome C., Streit, Fabian, Frank, Josef, Witt, Stephanie H., Treutlein, Jens, Baune, Bernhard T., Moebus, Susanne, Joeckel, Karl-Heinz, Forstner, Andreas J., Noethen, Markus M., Rietschel, Marcella, Sartorius, Alexander, Kranaster, Laura, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H. R. ... Sullivan, Patrick F. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180 (1), 35-45. doi: 10.1002/ajmg.b.32700 |