2018 Journal Article Correction to: lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signalingZannas, Anthony S., Arloth, Janine, Carrillo-Roa, Tania, Iurato, Stella, Röh, Simone, Ressler, Kerry J., Nemeroff, Charles B., Smith, Alicia K., Bradley, Bekh, Heim, Christine, Menke, Andreas, Lange, Jennifer F., Brückl, Tanja, Ising, Marcus, Wray, Naomi R., Erhardt, Angelika, Binder, Elisabeth B. and Mehta, Divya (2018). Correction to: lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology, 19 (1) 61, 61-61. doi: 10.1186/s13059-018-1441-1 |
2018 Journal Article GWAS on family history of Alzheimer's diseaseMarioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer's disease. Translational Psychiatry, 8 (1) 99, 99. doi: 10.1038/s41398-018-0150-6 |
2018 Journal Article Comparison of genotypic and phenotypic correlations: Cheverud's conjecture in humansSodini, Sebastian M., Kemper, Kathryn E., Wray, Naomi R. and Trzaskowski, Maciej (2018). Comparison of genotypic and phenotypic correlations: Cheverud's conjecture in humans. Genetics, 209 (3), 941-948. doi: 10.1534/genetics.117.300630 |
2018 Journal Article Familiality of psychiatric disorders and risk of postpartum psychiatric episodes: a population-based cohort studyBauer, Anna E., Maegbaek, Merete L., Liu, Xiaoqin, Wray, Naomi R., Sullivan, Patrick F., Miller, William C., Meltzer-Brody, Samantha and Munk-Olsen, Trine (2018). Familiality of psychiatric disorders and risk of postpartum psychiatric episodes: a population-based cohort study. The American Journal of Psychiatry, 175 (8), appiajp201817111184-791. doi: 10.1176/appi.ajp.2018.17111184 |
2018 Journal Article Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressionWray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3 |
2018 Journal Article Hypermetabolism in ALS is associated with greater functional decline and shorter survivalSteyn, Frederik J., Ioannides, Zara A., van Eijk, Ruben P. A., Heggie, Susan, Thorpe, Kathryn A., Ceslis, Amelia, Heshmat, Saman, Henders, Anjali K., Wray, Naomi R., van den Berg, Leonard H., Henderson, Robert D., McCombe, Pamela A. and Ngo, Shyuan T. (2018). Hypermetabolism in ALS is associated with greater functional decline and shorter survival. Journal of Neurology, Neurosurgery, and Psychiatry, 89 (10), jnnp-2017. doi: 10.1136/jnnp-2017-317887 |
2018 Journal Article Sizing up whole-genome sequencing studies of common diseasesWray, Naomi R. and Gratten, Jacob (2018). Sizing up whole-genome sequencing studies of common diseases. Nature Genetics, 50 (5), 635-637. doi: 10.1038/s41588-018-0113-0 |
2018 Journal Article Signatures of negative selection in the genetic architecture of human complex traitsZeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, McRae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. Nature Genetics, 50 (5), 746-753. doi: 10.1038/s41588-018-0101-4 |
2018 Journal Article Improving genetic prediction by leveraging genetic correlations among human diseases and traitsMaier, Robert M, Zhu, Zhihong, Lee, Sang Hong, Trzaskowski, Maciej, Ruderfer, Douglas M, Stahl, Eli A, Ripke, Stephan, Wray, Naomi R, Yang, Jian, Visscher, Peter M and Robinson, Matthew R (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications, 9 (1) 989, 989. doi: 10.1038/s41467-017-02769-6 |
2018 Journal Article Integrative analysis of omics summary data reveals putative mechanisms underlying complex traitsWu, Yang, Zeng, Jian, Zhang, Futao, Zhu, Zhihong, Qi, Ting, Zheng, Zhili, Lloyd-Jones, Luke R., Marioni, Riccardo E., Martin, Nicholas G., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. Nature Communications, 9 (918) 918, 918. doi: 10.1038/s41467-018-03371-0 |
2018 Journal Article Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selectionPardiñas, Antonio F, Holmans, Peter, Pocklington, Andrew J, Escott-Price, Valentina, Ripke, Stephan, Carrera, Noa, Legge, Sophie E, Bishop, Sophie, Cameron, Darren, Hamshere, Marian L, Han, Jun, Hubbard, Leon, Lynham, Amy, Mantripragada, Kiran, Rees, Elliott, MacCabe, James H, McCarroll, Steven A, Baune, Bernhard T, Breen, Gerome, Byrne, Enda M., Dannlowski, Udo, Eley, Thalia C, Hayward, Caroline, Martin, Nicholas G., McIntosh, Andrew M, Plomin, Robert, Porteous, David J, Wray, Naomi R, Caballero, Armando ... CRESTAR Consortium (2018). Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 50 (3), 381-389. doi: 10.1038/s41588-018-0059-2 |
2018 Journal Article Reply to Kardos et al.: estimation of inbreeding depression from SNP dataYengo, Loic, Zhu, Zhihong, Wray, Naomi R., Weir, Bruce S., Yang, Jian, Robinson, Matthew R. and Visscher, Peter M. (2018). Reply to Kardos et al.: estimation of inbreeding depression from SNP data. Proceedings of the National Academy of Sciences, 115 (11), E2494-E2495. doi: 10.1073/pnas.1718598115 |
2018 Journal Article The value of polygenic analyses in psychiatryMiddeldorp, Christel M. and Wray, Naomi R. (2018). The value of polygenic analyses in psychiatry. World Psychiatry, 17 (1), 26-28. doi: 10.1002/wps.20480 |
2018 Journal Article GWAS of epigenetic aging rates in blood reveals a critical role for TERTLu, Ake T., Xue, Luting, Salfati, Elias L., Chen, Brian H., Ferrucci, Luigi, Levy, Daniel, Joehanes, Roby, Murabito, Joanne M., Kiel, Douglas P., Tsai, Pei-Chien, Yet, Idil, Bell, Jordana T., Mangino, Massimo, Tanaka, Toshiko, McRae, Allan F., Marioni, Riccardo E., Visscher, Peter M., Wray, Naomi R., Deary, Ian J., Levine, Morgan E., Quach, Austin, Assimes, Themistocles, Tsao, Philip S., Absher, Devin, Stewart, James D., Li, Yun, Reiner, Alex P., Hou, Lifang, Baccarelli, Andrea A. ... Horvath, Steve (2018). GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications, 9 (1) 387, 387. doi: 10.1038/s41467-017-02697-5 |
2018 Journal Article Causal associations between risk factors and common diseases inferred from GWAS summary dataZhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J, Visscher, Peter M, Wray, Naomi R and Yang, Jian (2018). Causal associations between risk factors and common diseases inferred from GWAS summary data. Nature Communications, 9 (1) 224, 224. doi: 10.1038/s41467-017-02317-2 |
2018 Journal Article Genome-wide gene-environment interaction in depression: a systematic evaluation of candidate genes: the childhood trauma working-group of PGC-MDDVan der Auwera, Sandra, Peyrot, Wouter J., Milaneschi, Yuri, Hertel, Johannes, Baune, Bernhard, Breen, Gerome, Byrne, Enda, Dunn, Erin C, Fisher, Helen, Homuth, Georg, Levinson, Douglas, Lewis, Cathryn, Mills, Natalie, Mullins, Niamh, Nauck, Matthias, Pistis, Giorgio, Preisig, Martin, Rietschel, Marcella, Ripke, Stephan, Sullivan, Patrick, Teumer, Alexander, Völzke, Henry, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Boomsma, Dorret I., Wray, Naomi R., Penninx, Brenda and Grabe, Hans (2018). Genome-wide gene-environment interaction in depression: a systematic evaluation of candidate genes: the childhood trauma working-group of PGC-MDD. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 177 (1), 40-49. doi: 10.1002/ajmg.b.32593 |
2018 Conference Publication Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorderTrzaskowski, Maciej, Wray, Naomi and Sullivan, Patrick (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder. Human Genome Meeting 2018, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: BioMed Central . doi: 10.1186/s40246-018-0138-6 |
2018 Conference Publication Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiologyVisscher, Peter M., Wray, Naomi R. and Yang, Jian (2018). Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology. 27th Annual Meeting of the International Genetic Epidemiology Society (IGES), San Diego, CA, United States, 14-16 October 2018. Hoboken, NJ, United States: John Wiley & Sons. |
2018 Conference Publication Fine-mapping reveals complex genetic architecture underlying DNA methylationChundru, V. Kartik, Marioni, Riccardo E., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2018). Fine-mapping reveals complex genetic architecture underlying DNA methylation. Human Genome Meeting, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications. doi: 10.1186/s40246-018-0138-6 |
2018 Journal Article Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK BiobankBarbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006 |