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2019

Conference Publication

Genetics of depression

Flint, Jonathan, McIntosh, Andrew and Wray, Naomi (2019). Genetics of depression. 27th World Congress of Psychiatric Genetics, Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.07.106

Genetics of depression

2018

Journal Article

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Stevenson, Anna J., McCartney, Daniel L., Harris, Sarah E., Taylor, Adele M., Redmond, Paul, Starr, John M., Zhang, Qian, McRae, Allan F., Wray, Naomi R., Spires-Jones, Tara L., McColl, Barry W., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2018). Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing. Clinical Epigenetics, 10 (1) 159, 159. doi: 10.1186/s13148-018-0585-x

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

2018

Journal Article

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

Yap, Chloe X., Sidorenko, Julia, Wu, Yang, Kemper, Kathryn E., Yang, Jian, Wray, Naomi R., Robinson, Matthew R. and Visscher, Peter M. (2018). Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. Nature Communications, 9 (1) 5407, 5407. doi: 10.1038/s41467-018-07862-y

Dissection of genetic variation and evidence for pleiotropy in male pattern baldness

2018

Journal Article

Identification of 55,000 replicated DNA methylation QTL

McRae, Allan F., Marioni, Riccardo E., Shah, Sonia, Yang, Jian, Powell, Joseph E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Bowdler, Lisa, Painter, Jodie N., Murphy, Lee, Martin, Nicholas G., Starr, John M., Wray, Naomi R., Deary, Ian J., Visscher, Peter M. and Montgomery, Grant W. (2018). Identification of 55,000 replicated DNA methylation QTL. Scientific Reports, 8 (1) 17605, 17605. doi: 10.1038/s41598-018-35871-w

Identification of 55,000 replicated DNA methylation QTL

2018

Journal Article

The association between neonatal vitamin D status and risk of schizophrenia

Eyles, Darryl W., Trzaskowski, Maciej, Vinkhuyzen, Anna A. E., Mattheisen, Manuel, Meier, Sandra, Gooch, Helen, Anggono, Victor, Cui, Xiaoying, Tan, Men Chee, Burne, Thomas H. J., Jang, Se Eun, Kvaskoff, David, Hougaard, David M., Nørgaard-Pedersen, Bent, Cohen, Arieh, Agerbo, Esben, Pedersen, Carsten B., Børglum, Anders D., Mors, Ole, Sah, Pankaj, Wray, Naomi R., Mortensen, Preben B. and McGrath, John J. (2018). The association between neonatal vitamin D status and risk of schizophrenia. Scientific Reports, 8 (1) 17692, 17692. doi: 10.1038/s41598-018-35418-z

The association between neonatal vitamin D status and risk of schizophrenia

2018

Journal Article

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Arnau-Soler, Aleix, Adams, Mark J., Hayward, Caroline, Thomson, Pippa A., Porteous, David, Campbell, Archie, Smith, Blair H., Black, Corri, Padmanabhan, Sandosh, McIntosh, Andrew, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na ... Sullivan, Patrick F. (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLoS ONE, 13 (12) e0209160, e0209160. doi: 10.1371/journal.pone.0209160

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

2018

Journal Article

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (vol 84, pg 138, 2018)

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T., Breen, G., Levinson, D. F., Lewis, C. M., Martin, N. G., Nelson, E. N., Boomsma, D., Grabe, H. J., Wray, N. R. and Penninx, B. W. J. H. (2018). Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (vol 84, pg 138, 2018). Biological Psychiatry, 84 (11), 857-857.

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (vol 84, pg 138, 2018)

2018

Journal Article

PPD ACT: an app-based genetic study of postpartum depression

Guintivano, Jerry, Krohn, Holly, Lewis, Carol, Byrne, Enda M., Henders, Anjali K., Ploner, Alexander, Kirk, Katherine, Martin, Nicholas G., Milgrom, Jeannette, Wray, Naomi R., Sullivan, Patrick F. and Meltzer-Brody, Samantha (2018). PPD ACT: an app-based genetic study of postpartum depression. Translational Psychiatry, 8 (1) 260, 260. doi: 10.1038/s41398-018-0305-5

PPD ACT: an app-based genetic study of postpartum depression

2018

Journal Article

Imprint of assortative mating on the human genome

Yengo, Loic, Robinson, Matthew R., Keller, Matthew C., Kemper, Kathryn E., Yang, Yuanhao, Trzaskowski, Maciej, Gratten, Jacob, Turley, Patrick, Cesarini, David, Benjamin, Daniel J., Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2018). Imprint of assortative mating on the human genome. Nature Human Behaviour, 2 (12), 948-954. doi: 10.1038/s41562-018-0476-3

Imprint of assortative mating on the human genome

2018

Journal Article

Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537))

Yap, Chloe X., Sidorenko, Julia, Marioni, Riccardo E., Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2018). Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537)). Nature communications, 9 (1) 4953, 4953. doi: 10.1038/s41467-018-07400-w

Erratum: Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness (Nature communications (2018) 9 1 (2537))

2018

Journal Article

Is schizophrenia a risk factor for breast cancer?—evidence from genetic data

Byrne, Enda M., Ferreira, Manuel A.R., Xue, Angli, Lindström, Sara, Jiang, Xia, Yang, Jian, Easton, Douglas F., Wray, Naomi R. and Chenevix-Trench, Georgia (2018). Is schizophrenia a risk factor for breast cancer?—evidence from genetic data. Schizophrenia Bulletin, 45 (6), 1251-1256. doi: 10.1093/schbul/sby162

Is schizophrenia a risk factor for breast cancer?—evidence from genetic data

2018

Journal Article

Genotype effects contribute to variation in longitudinal methylome patterns in older people

Zhang, Qian, Marioni, Riccardo E., Robinson, Matthew R., Higham, Jon, Sproul, Duncan, Wray, Naomi R., Deary, Ian J., McRae, Allan F. and Visscher, Peter M. (2018). Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine, 10 (1) 75, 75. doi: 10.1186/s13073-018-0585-7

Genotype effects contribute to variation in longitudinal methylome patterns in older people

2018

Journal Article

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

de Jong, Simone, Abdalla Diniz, Mateus Jose, Saloma, Andiara, Gadelha, Ary, Santoro, Marcos L., Ota, Vanessa K., Noto, Cristiano, Curtis, Charlesg, Newhouse, Stephen J., Patel, Hamel, Hall, Lynsey S., O'Reilly, Paul F., Belangero, Sintia, Bressan, Rodrigo A., Breen, Gerome, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B. ... Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1 (163) 163. doi: 10.1038/s42003-018-0155-y

Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

2018

Journal Article

Epigenetic prediction of complex traits and death

McCartney, Daniel L., Hillary, Robert F., Stevenson, Anna J., Ritchie, Stuart J., Walker, Rosie M., Zhang, Qian, Morris, Stewart W., Bermingham, Mairead L., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Gale, Catharine R., Porteous, David J., Haley, Chris S., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J. and Marioni, Riccardo E. (2018). Epigenetic prediction of complex traits and death. Genome Biology, 19 (1) 136, 136. doi: 10.1186/s13059-018-1514-1

Epigenetic prediction of complex traits and death

2018

Journal Article

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

Alvares, Gail A., Dawson, Paul A., Dissanayake, Cheryl, Eapen, Valsamma, Gratten, Jacob, Grove, Rachel, Henders, Anjali, Heussler, Helen, Lawson, Lauren, Masi, Anne, Raymond, Emma, Rose, Felicity, Wallace, Leanne, Wray, Naomi R. and Whitehouse, Andrew J. O. (2018). Study protocol for the Australian autism biobank: an international resource to advance autism discovery research. BMC Pediatrics, 18 (1) 284, 284. doi: 10.1186/s12887-018-1255-z

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

2018

Journal Article

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

Story Jovanova, Olivera, Nedeljkovic, Ivana, Derek, Spieler, Walker, Rosie M., Liu, Chunyu, Luciano, Michelle, Bressler, Jan, Brody, Jennifer, Drake, Amanda J., Evans, Kathryn L., Gondalia, Rahul, Kunze, Sonja, Kuhnel, Brigitte, Lahti, Jari, Lemaitre, Rozenn N., Marioni, Riccardo E., Swenson, Brenton, Himali, Jayandra Jung, Wu, Hongsheng, Li, Yun, McRae, Allan F., Russ, Tom C., Stewart, James, Wang, Zhiying, Zhang, Guosheng, Ladwig, Karl-Heinz, Uitterlinden, Andre G., Guo, Xiuqing, Peters, Annette ... Amin, Najaf (2018). DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies. JAMA Psychiatry, 75 (9), 949-959. doi: 10.1001/jamapsychiatry.2018.1725

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

2018

Journal Article

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, Guiyan, Gratten, Jacob, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R. and Lee, Sang Hong (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports, 8 (1) 10168, 10168. doi: 10.1038/s41598-018-28160-z

Age at first birth in women is genetically associated with increased risk of schizophrenia

2018

Journal Article

Misestimation of heritability and prediction accuracy of male-pattern baldness

Yap, Chloe X., Sirodenko, Julia, Marioni, Riccardo E., Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2018). Misestimation of heritability and prediction accuracy of male-pattern baldness. Nature Communications, 9 (1) 2537, 2537. doi: 10.1038/s41467-018-04807-3

Misestimation of heritability and prediction accuracy of male-pattern baldness

2018

Journal Article

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

van Rheenen, Wouter, Pulit, Sara L., Dekker, Annelot M., Al Khleifat, Ahmad, Brands, William J., Iacoangeli, Alfredo, Kenna, Kevin P., Kavak, Ersen, Kooyman, Maarten, McLaughlin, Russell L., Middelkoop, Bas, Moisse, Matthieu, Schellevis, Raymond D., Shatunov, Aleksey, Sproviero, William, Tazelaar, Gijs H. P., van der Spek, Rick A. A., van Doormaal, Perry T. C., van Eijk, Kristel R., van Vugt, Joke, Basak, A. Nazli, Blair, Ian P., Glass, Jonathan D., Hardiman, Orla, Hide, Winston, Landers, John E., Mora, Jesus S., Morrison, Karen E., Newhouse, Stephen ... Veldink, Jan H. (2018). Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis. European Journal of Human Genetics, 26 (10), 1537-1546. doi: 10.1038/s41431-018-0177-4

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

2018

Journal Article

Analysis of shared heritability in common disorders of the brain

Anttila, Verneri, Bulik-Sullivan, Brendan, Finucane, Hilary K., Walters, Raymond K., Bras, Jose, Duncan, Laramie, Escott-Price, Valentina, Falcone, Guido J., Gormley, Padhraig, Malik, Rainer, Patsopoulos, Nikolaos A., Ripke, Stephan, Wei, Zhi, Yu, Dongmei, Lee, Phil H., Turley, Patrick, Grenier-Boley, Benjamin, Chouraki, Vincent, Kamatani, Yoichiro, Berr, Claudine, Letenneur, Luc, Hannequin, Didier, Amouyel, Philippe, Boland, Anne, Deleuze, Jean-Francois, Duron, Emmanuelle, Vardarajan, Badri N., Reitz, Christiane, Goate, Alison M. ... The Brainstorm Consortium (2018). Analysis of shared heritability in common disorders of the brain. Science, 360 (6395) 8757, 1313-+. doi: 10.1126/science.aap8757

Analysis of shared heritability in common disorders of the brain