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2017

Journal Article

Using information of relatives in genomic prediction to apply effective stratified medicine

Lee, S. Hong, Weerasinghe, W. M. Shalanee P., Wray, Naomi R., Goddard, Michael E. and Van Der Werf, Julius H. J. (2017). Using information of relatives in genomic prediction to apply effective stratified medicine. Scientific Reports, 7 (1) 42091, 42091. doi: 10.1038/srep42091

Using information of relatives in genomic prediction to apply effective stratified medicine

2017

Journal Article

Trajectories of maternal depression: a 27-year population-based prospective study

Najman, J. M., Plotnikova, M., Williams, G. M., Alati, R., Mamun, A. A., Scott, J., Wray, N. and Clavarino, A. M. (2017). Trajectories of maternal depression: a 27-year population-based prospective study. Epidemiology and Psychiatric Sciences, 26 (1), 79-88. doi: 10.1017/S2045796015001109

Trajectories of maternal depression: a 27-year population-based prospective study

2017

Journal Article

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Gratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2017). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Obstetrical and Gynecological Survey, 72 (2), 96-96. doi: 10.1097/01.OGX.0000512485.13448.C7

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

2017

Journal Article

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan, North, Kari, Sundstrom, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F., Harris, Sarah E., Gibson, Jude, Redmond, Paul, Corley, Janie ... Deary, Ian J. (2017). Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach. PLoS Medicine, 14 (1) e1002215, e1002215. doi: 10.1371/journal.pmed.1002215

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

2017

Conference Publication

The potential impact of falsely classified controls on the SNP-based heritability of depression

Peyrot, Wouter J., Penninx, Brenda and Wray, Naomi (2017). The potential impact of falsely classified controls on the SNP-based heritability of depression. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

The potential impact of falsely classified controls on the SNP-based heritability of depression

2017

Conference Publication

Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Maier, Robert, Wray, Naomi, Robinson, Matt and Lee, Sang Hong (2017). Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

2017

Conference Publication

Genetic architecture insights from joint investigations of rare CNVS and common SNPS

Bergen, Sarah, Kendler, Kenneth and Wray, Naomi (2017). Genetic architecture insights from joint investigations of rare CNVS and common SNPS. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Genetic architecture insights from joint investigations of rare CNVS and common SNPS

2017

Conference Publication

Multivariate genetic risk scores increase accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Maier, Robert, Wray, Naomi and Lee, Sang Hong (2017). Multivariate genetic risk scores increase accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Multivariate genetic risk scores increase accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

2017

Conference Publication

Evidence for genetic overlap between schizophrenia and maternal age at first birth

Mehta, Divya, Tropf, Felix, Gratten, Jacob, Bacanu, Silviu, Bakshi, Andrew, Mowry, Bryan, Kendler, Kenneth, Yang, Jian, Visscher, Peter, McGrath, John, Mills, Melinda, Wray, Naomi and Lee, Sang Hong (2017). Evidence for genetic overlap between schizophrenia and maternal age at first birth. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, ON, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2015.09.010

Evidence for genetic overlap between schizophrenia and maternal age at first birth

2017

Journal Article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, Christian R., Howrigan, Daniel P., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wu, Wenting, Greer, Douglas S., Antaki, Danny, Shetty, Aniket, Holmans, Peter A., Pinto, Dalila, Gujral, Madhusudan, Brandler, William M., Malhotra, Dheeraj, Wang, Zhouzhi, Fuentes Fajarado, Karin V., Maile, Michelle S., Ripke, Stephan, Agartz, Ingrid, Albus, Margot, Alexander, Madeline, Amin, Farooq, Atkins, Joshua, Bacanu, Silviu A., Belliveau, Richard A., Jr., Bergen, Sarah E., Bertalan, Marcelo, Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W. ... Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 49 (1), 27-35. doi: 10.1038/ng.3725

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

2017

Conference Publication

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans

Vinkhuyzen, Anna, John, Sujit, Periyasamy, Sathish, Wray, Naomi, Thara, Rangaswamy and Mowry, Bryan (2017). Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans

2017

Conference Publication

High loading of polygenic risk in cases with chronic schizophrenia

Meier, Sandra, Agerbo, Esben, Maier, Robert, Pedersen, Carsten B., Lang, Maren, Ripke, Stephan, Werge, Thomas, Mors, Ole, Hougaard, David, Borglum, Anders, Wray, Naomi, Rietschel, Marcella, Nordentoft, Merete, Mortensen, Preben Bo and Mattheisen, Manuel (2017). High loading of polygenic risk in cases with chronic schizophrenia. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

High loading of polygenic risk in cases with chronic schizophrenia

2017

Conference Publication

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

2017

Conference Publication

Polygenic score methodology in psychiatric genetics

O'Reilly, Paul, Wray, Naomi and Breen, Gerome (2017). Polygenic score methodology in psychiatric genetics. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Polygenic score methodology in psychiatric genetics

2017

Conference Publication

Characterizing an inverse axis between orthogonal sources of genetic risk

Davis, Lea, Lee, Sang Hong, Gamazon, Eric, Im, Hae Kyung, Yu, Dongmei, McGrath, Lauren, Williams, Stephanie, Cook, Edwin, Sullivan, Patrick, Sutcliffe, James, Knowles, James, Mathews, Carol, Scharf, Jeremiah, Wray, Naomi and Cox, Nancy (2017). Characterizing an inverse axis between orthogonal sources of genetic risk. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Characterizing an inverse axis between orthogonal sources of genetic risk

2016

Journal Article

Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder

Zeng, Yanni, Navarro, Pau, Shirali, Masoud, Howard, David M., Adams, Mark J., Hall, Lynsey S., Clarke, Toni-Kim, Thomson, Pippa A., Smith, Blair H., Murray, Alison, Padmanabhan, Sandosh, Hayward, Caroline, Boutin, Thibaud, MacIntyre, Donald J., Lewis, Cathryn M., Wray, Naomi R., Mehta, Divya, Penninx, Brenda W. J. H., Milaneschi, Yuri, Baune, Bernhard T., Air, Tracy, Hottenga, Jouke-Jan, Mbarek, Hamdi, Castelao, Enrique, Pistis, Giorgio, Schulze, Thomas G., Streit, Fabian, Forstner, Andreas J., Byrne, Enda M. ... McIntosh, Andrew M. (2016). Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder. Biological Psychiatry, 82 (5), 312-321. doi: 10.1016/j.biopsych.2016.12.012

Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder

2016

Journal Article

A DNA methylation biomarker of alcohol consumption

Liu, C., Marioni, R. E., Hedman, K., Pfeiffer, L., Tsai, P. -C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C., Mendelson, M. M., Joehanes, R., Liang, L., Love, S. -A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H. ... Levy, D. (2016). A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry, 23 (2), 422-433. doi: 10.1038/mp.2016.192

A DNA methylation biomarker of alcohol consumption

2016

Journal Article

Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits

Peyrot, Wouter J., Robinson, Matthew R., Penninx, Brenda W. J. H. and Wray, Naomi R. (2016). Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits. JAMA Psychiatry, 73 (11), 1189-1195. doi: 10.1001/jamapsychiatry.2016.2566

Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits

2016

Journal Article

No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study

Johnson, Emma C., Bjelland, Douglas W., Howrigan, Daniel P., Abdellaoui, Abdel, Breen, Gerome, Borglum, Anders, Cichon, Sven, Degenhardt, Franziska, Forstner, Andreas J., Frank, Josef, Genovese, Giulio, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffman, Per, Maier, Wolfgang, Mattheisen, Manuel, Morris, Derek, Mowry, Bryan, Muller-Mhysok, Betram, Neale, Benjamin, Nenadic, Igor, Nothen, Markus M., O'Dushlaine, Colm, Rietschel, Marcella, Ruderfer, Douglas M., Rujescu, Dan, Schulze, Thomas G., Simonson, Matthew A., Stahl, Eli ... Keller, Matthew C. (2016). No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study. PLoS Genetics, 12 (10) e1006343, e1006343. doi: 10.1371/journal.pgen.1006343

No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study

2016

Journal Article

Meta-analysis of genome-wide association studies of anxiety disorders

Otowa, T., Hek, K., Lee, M., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T., Aggen, S. H., Adkins, D., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., Der Auwera, S. V., Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J. -J., Direk, N., Hofman, A., Uitterlinden, A., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F. ... Hettema, J. M. (2016). Meta-analysis of genome-wide association studies of anxiety disorders. Molecular Psychiatry, 21 (10), 1391-1399. doi: 10.1038/mp.2015.197

Meta-analysis of genome-wide association studies of anxiety disorders