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2015

Journal Article

Lifetime Stress Accelerates Epigenetic Aging

Zannas, A., Carrillo-Roa, T., Iurato, S., Ressler, K., Nemeroff, C., Smith, A., Lange, J., Bradley, B., Heim, C., Brückl, T., Ising, M., Wray, N., Erhardt, A., Binder, E. and Mehta, D. (2015). Lifetime Stress Accelerates Epigenetic Aging. European Psychiatry, 30. doi: 10.1016/s0924-9338(15)31949-0

Lifetime Stress Accelerates Epigenetic Aging

2015

Journal Article

Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke

Holliday, Elizabeth G., Traylor, Matthew, Malik, Rainer, Bevan, Steve, Falcone, Guido, Hopewell, Jemma C., Cheng, Yu-Ching, Cotlarciuc, Ioana, Bis, Joshua C., Boerwinkle, Eric, Boncoraglio, Giorgio B., Clarke, Robert, Cole, John W., Fornage, Myriam, Furie, Karen L., Ikram, M. Arfan, Jannes, Jim, Kittner, Steven J., Lincz, Lisa F., Maguire, Jane M., Meschia, James F., Mosley, Thomas H., Nalls, Mike A., Oldmeadow, Christopher, Parati, Eugenio A., Psaty, Bruce M., Rothwell, Peter M., Seshadri, Sudha, Scott, Rodney J. ... Wray, Naomi R. (2015). Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke. Stroke, 46 (3), 615-615. doi: 10.1161/STROKEAHA.114.007930

Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke

2015

Journal Article

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Maier, Robert, Moser, Gerhard, Chen, Guo-Bo, Ripke, Stephan, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Coryell, William, Potash, James B., Scheftner, William A., Shi, Jianxin, Weissman, Myrna M., Hultman, Christina M., Landen, Mikael, Levinson, Douglas F., Kendler, Kenneth S., Smoller, Jordan W., Wray, Naomi R. and Lee, S. Hong (2015). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. American Journal of Human Genetics, 96 (2), 283-294. doi: 10.1016/j.ajhg.2014.12.006

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

2015

Journal Article

Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder

Byrne, Enda M, Raheja, Uttam K, Stephens, Sarah H, Heath, Andrew C, Madden, Pamela A, Vaswani, Dipika, Nijjar, Gagan V, Ryan, Kathleen A, Youssufi, Hassaan, Gehrman, Philip R, Shuldiner, Alan R, Martin, Nicholas G, Montgomery, Grant W, Wray, Naomi R, Nelson, Elliot C, Mitchell, Braxton D, Postolache, Teodor T, Psychiatric Genetics Consortium Major Depressive Disorder Working Group and Middeldorp, Christel (2015). Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. Journal of Clinical Psychiatry, 76 (2), 128-134. doi: 10.4088/JCP.14m08981

Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder

2015

Journal Article

Cohort profile update: the Mater-University of Queensland Study of Pregnancy (MUSP)

Najman, Jake M., Alati, Rosa, Bor, William, Clavarino, Alexandra, Mamun, Abdullah, McGrath, John J., McIntyre, David, O'Callaghan, Michael, Scott, James, Shuttlewood, Greg, Williams, Gail M. and Wray, Naomi (2015). Cohort profile update: the Mater-University of Queensland Study of Pregnancy (MUSP). International Journal of Epidemiology, 44 (1), 78-78f. doi: 10.1093/ije/dyu234

Cohort profile update: the Mater-University of Queensland Study of Pregnancy (MUSP)

2015

Journal Article

Heritability of Transforming Growth Factor-β1 and Tumor Necrosis Factor-Receptor Type 1 Expression and Vitamin D Levels in Healthy Adolescent Twins

Mills, Natalie T., Wright, Margaret J., Henders, Anjali K., Eyles, Darryl W., Baune, Bernhard T., McGrath, John J., Byrne, Edna M., Hansell, Narelle K., Birosova, Eva, Scott, James G., Martin, Nicholas G., Montgomery, Grant W., Wray, Naomi R. and Vinkhuyzen, Anna A. E. (2015). Heritability of Transforming Growth Factor-β1 and Tumor Necrosis Factor-Receptor Type 1 Expression and Vitamin D Levels in Healthy Adolescent Twins. Twin Research and Human Genetics, 18 (1), 28-35. doi: 10.1017/thg.2014.70

Heritability of Transforming Growth Factor-β1 and Tumor Necrosis Factor-Receptor Type 1 Expression and Vitamin D Levels in Healthy Adolescent Twins

2015

Journal Article

DNA methylation age of blood predicts all-cause mortality in later life

Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Chen, Brian H., Colicino, Elena, Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Feinberg, Andrew P., Fallin, M. Daniele, Multhaup, Michael L., Jaffe, Andrew E., Joehanes, Roby, Schwartz, Joel, Just, Allan C., Lunetta, Kathryn L., Murabito, Joanne M., Starr, John M., Horvath, Steve, Baccarelli, Andrea A., Levy, Daniel, Visscher, Peter M. ... Deary, Ian J. (2015). DNA methylation age of blood predicts all-cause mortality in later life. Genome Biology, 16 (1) 25, 25.1-25.12. doi: 10.1186/s13059-015-0584-6

DNA methylation age of blood predicts all-cause mortality in later life

2015

Journal Article

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

O'Dushlaine, Colm, Rossin, Lizzy, Lee, Phil H., Duncan, Laramie, Parikshak, Neelroop N., Newhouse, Stephen, Ripke, Stephan, Neale, Benjamin M., Purcell, Shaun M., Posthuma, Danielle, Nurnberger, John I., Lee, S. Hong, Faraone, Stephen V., Perlis, Roy H., Mowry, Bryan J, Thapar, Anita, Goddard, Michael E., Witte, John S., Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A., Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E., Asherson, Philip, Azevedo, Maria H. ... Breen, Gerome (2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience, 18 (2), 199-209. doi: 10.1038/nn.3922

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

2015

Journal Article

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

Lee, S. Hong, Byrne, Enda M., Hultman, Christina M., Kahler, Anna, Vinkhuyzen, Anna A. E., Ripke, Stephan, Andreassen, Ole A., Frisell, Thomas, Gusev, Alexander, Hu, Xinli, Karlsson, Robert, Mantzioris, Vasilis X., McGrath, John J., Mehta, Divya, Stahl, Eli A., Zhao, Qiongyi, Kendler, Kenneth S., Sullivan, Patrick F., Price, Alkes L., O'Donovan, Michael, Okada, Yukinori, Mowry, Bryan J., Raychaudhuri, Soumya, Wray, Naomi R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Rheumatoid Arthritis Consortium International and Visscher, Peter M . (2015). New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology, 44 (5) dyv136, 1-16. doi: 10.1093/ije/dyv136

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

2015

Conference Publication

Early Career Psychiatrists Special Interest Group Symposium

Mills, N., Nelson, E., Scott, J., Whitfield, J., Martin, N., Wright, M., Wray, N., Byrne, E. and Martin, J. (2015). Early Career Psychiatrists Special Interest Group Symposium. The Royal Australian and New Zealand College of Psychiatrists 2015 Congress: Measurers and Thinkers: Psychiatry as Science and Art, Brisbane, QLD Australia, 3-15 May 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0004867415578344

Early Career Psychiatrists Special Interest Group Symposium

2015

Conference Publication

Lifetime stress accelerates epigenetic aging

Zannas, A., Carrillo-Roa, T., Iurato, S., Arloth, J., Roeh, S., Ressler, K., Nemeroff, C., Smith, A., Bradley, B., Heim, C., Lange, J., Brueckl, T., Ising, M., Wray, N., Erhardt, A., Binder, E. and Mehta, D. (2015). Lifetime stress accelerates epigenetic aging. 28th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Amsterdam Netherlands, Aug 29-Sep 01, 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0924-977X(15)30161-9

Lifetime stress accelerates epigenetic aging

2015

Conference Publication

Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety

Mills, N., Scott, J., Whitfield, J., Wright, M., Martin, N., Wray, N. and Byrne, E. (2015). Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety. The Royal Australian and New Zealand College of Psychiatrists 2015 Congress: Measurers and Thinkers: Psychiatry as Science and Art, Brisbane, QLD Australia, 3-15 May 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0004867415578344

Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety

2015

Conference Publication

Characterizing an inverse axis between orthogonal sources of genetic risk

Davis, Lea K., Lee, S. Hong, Gamazon, Eric R., Im, Hae-Kyung, Yu, Dongmei, Williams, Stephanie, Sullivan, Patrick F., Mathews, Carol, Knowles, James, Scharf, Jeremiah, Wray, Naomi and Cox, Nancy J. (2015). Characterizing an inverse axis between orthogonal sources of genetic risk. Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Baltimore Md, Oct 04-06 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/gepi.21916

Characterizing an inverse axis between orthogonal sources of genetic risk

2015

Conference Publication

Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus

Jhaveri, D., O'Keeffe, I., Robinson, G., Zhao, Q-Y., Zhang, Z. H., Nink, V., Osborne, G., Wray, N. and Bartlett, P. (2015). Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus

2015

Conference Publication

Investigating the Relationship Between C-Reactive Protein Genetic Profile Scores and Depression

Mills, N., Nelson, E., Scott, J., Whitfield, J., Martin, N., Wright, M., Wray, N. and Byrne, E. (2015). Investigating the Relationship Between C-Reactive Protein Genetic Profile Scores and Depression. The Royal Australian and New Zealand College of Psychiatrists 2015 Congress: Measurers and Thinkers: Psychiatry as Science and Art, Brisbane, QLD Australia, 3-15 May 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0004867415578344

Investigating the Relationship Between C-Reactive Protein Genetic Profile Scores and Depression

2014

Journal Article

The contribution of genetic variants to disease depends on the ruler

Witte, John S., Visscher, Peter M. and Wray, Naomi R. (2014). The contribution of genetic variants to disease depends on the ruler. Nature Reviews Genetics, 15 (11), 765-776. doi: 10.1038/nrg3786

The contribution of genetic variants to disease depends on the ruler

2014

Journal Article

Genetic and environmental exposures constrain epigenetic drift over the human life course

Shah, Sonia, McRae, Allan F., Marioni, Riccardo E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Starr, John M., Wray, Naomi R., Deary, Ian J. and Visscher, Peter M. (2014). Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research, 24 (11), 1725-1733. doi: 10.1101/gr.176933.114

Genetic and environmental exposures constrain epigenetic drift over the human life course

2014

Journal Article

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, Alexander, Lee, S. Hong, Trynka, Gosia, Finucane, Hilary, Vilhjálmsson, Bjarni J., Xu, Han, Zang, Chongzhi, Ripke, Stephan, Bulik-Sullivan, Brendan, Stahl, Eli, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kaehler, Anna K., Hultman, Christina M., Purcell, Shaun M., McCarroll, Steven A., Daly, Mark, Pasaniuc, Bogdan, Sullivan, Patrick F., Neale, Benjamin M., Wray, Naomi R., Raychaudhuri, Soumya, Price, Alkes L., Visscher, Peter M., Mowry, Bryan J., Psychosis Endophenotypes International Consortium and Wellcome Trust Case Control Consortium (2014). Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. American Journal of Human Genetics, 95 (5), 535-552. doi: 10.1016/j.ajhg.2014.10.004

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

2014

Journal Article

Novel directions for G × E analysis in psychiatry

Vinkhuyzen, A. A. E. and Wray, N. R. (2014). Novel directions for G × E analysis in psychiatry. Epidemiology and Psychiatric Sciences, 24 (1), 12-19. doi: 10.1017/S2045796014000584

Novel directions for G × E analysis in psychiatry

2014

Journal Article

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?

Levinson, Douglas F., Mostafavi, Sara, Milaneschi, Yuri, Rivera, Margarita, Ripke, Stephan, Wray, Naomi R. and Sullivan, Patrick F. (2014). Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?. Biological Psychiatry, 76 (7), 510-512. doi: 10.1016/j.biopsych.2014.07.029

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?