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2015

Conference Publication

Early Career Psychiatrists Special Interest Group Symposium

Mills, N., Nelson, E., Scott, J., Whitfield, J., Martin, N., Wright, M., Wray, N., Byrne, E. and Martin, J. (2015). Early Career Psychiatrists Special Interest Group Symposium. The Royal Australian and New Zealand College of Psychiatrists 2015 Congress: Measurers and Thinkers: Psychiatry as Science and Art, Brisbane, QLD Australia, 3-15 May 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0004867415578344

Early Career Psychiatrists Special Interest Group Symposium

2015

Conference Publication

Lifetime stress accelerates epigenetic aging

Zannas, A., Carrillo-Roa, T., Iurato, S., Arloth, J., Roeh, S., Ressler, K., Nemeroff, C., Smith, A., Bradley, B., Heim, C., Lange, J., Brueckl, T., Ising, M., Wray, N., Erhardt, A., Binder, E. and Mehta, D. (2015). Lifetime stress accelerates epigenetic aging. 28th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Amsterdam Netherlands, Aug 29-Sep 01, 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0924-977X(15)30161-9

Lifetime stress accelerates epigenetic aging

2015

Conference Publication

Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety

Mills, N., Scott, J., Whitfield, J., Wright, M., Martin, N., Wray, N. and Byrne, E. (2015). Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety. The Royal Australian and New Zealand College of Psychiatrists 2015 Congress: Measurers and Thinkers: Psychiatry as Science and Art, Brisbane, QLD Australia, 3-15 May 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0004867415578344

Using C-Reactive Protein Genetic Profile Scores to Predict Risk of Anxiety

2015

Conference Publication

Characterizing an inverse axis between orthogonal sources of genetic risk

Davis, Lea K., Lee, S. Hong, Gamazon, Eric R., Im, Hae-Kyung, Yu, Dongmei, Williams, Stephanie, Sullivan, Patrick F., Mathews, Carol, Knowles, James, Scharf, Jeremiah, Wray, Naomi and Cox, Nancy J. (2015). Characterizing an inverse axis between orthogonal sources of genetic risk. Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Baltimore Md, Oct 04-06 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/gepi.21916

Characterizing an inverse axis between orthogonal sources of genetic risk

2015

Conference Publication

Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus

Jhaveri, D., O'Keeffe, I., Robinson, G., Zhao, Q-Y., Zhang, Z. H., Nink, V., Osborne, G., Wray, N. and Bartlett, P. (2015). Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Presence of distinct, stimulus-specific subpopulations of quiescent precursors in the adult mouse hippocampus

2014

Journal Article

The contribution of genetic variants to disease depends on the ruler

Witte, John S., Visscher, Peter M. and Wray, Naomi R. (2014). The contribution of genetic variants to disease depends on the ruler. Nature Reviews Genetics, 15 (11), 765-776. doi: 10.1038/nrg3786

The contribution of genetic variants to disease depends on the ruler

2014

Journal Article

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, Alexander, Lee, S. Hong, Trynka, Gosia, Finucane, Hilary, Vilhjálmsson, Bjarni J., Xu, Han, Zang, Chongzhi, Ripke, Stephan, Bulik-Sullivan, Brendan, Stahl, Eli, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kaehler, Anna K., Hultman, Christina M., Purcell, Shaun M., McCarroll, Steven A., Daly, Mark, Pasaniuc, Bogdan, Sullivan, Patrick F., Neale, Benjamin M., Wray, Naomi R., Raychaudhuri, Soumya, Price, Alkes L., Visscher, Peter M., Mowry, Bryan J., Psychosis Endophenotypes International Consortium and Wellcome Trust Case Control Consortium (2014). Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. American Journal of Human Genetics, 95 (5), 535-552. doi: 10.1016/j.ajhg.2014.10.004

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

2014

Journal Article

Genetic and environmental exposures constrain epigenetic drift over the human life course

Shah, Sonia, McRae, Allan F., Marioni, Riccardo E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Starr, John M., Wray, Naomi R., Deary, Ian J. and Visscher, Peter M. (2014). Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research, 24 (11), 1725-1733. doi: 10.1101/gr.176933.114

Genetic and environmental exposures constrain epigenetic drift over the human life course

2014

Journal Article

Novel directions for G × E analysis in psychiatry

Vinkhuyzen, A. A. E. and Wray, N. R. (2014). Novel directions for G × E analysis in psychiatry. Epidemiology and Psychiatric Sciences, 24 (1), 12-19. doi: 10.1017/S2045796014000584

Novel directions for G × E analysis in psychiatry

2014

Journal Article

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?

Levinson, Douglas F., Mostafavi, Sara, Milaneschi, Yuri, Rivera, Margarita, Ripke, Stephan, Wray, Naomi R. and Sullivan, Patrick F. (2014). Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?. Biological Psychiatry, 76 (7), 510-512. doi: 10.1016/j.biopsych.2014.07.029

Genetic studies of major depressive disorder: why are there no genome-wide association study findings and what can we do about it?

2014

Journal Article

Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data

Chen, Guo-Bo, Lee, Sang Hong, Brion, Marie-Jo A., Montgomery, Grant W., Wray, Naomi R., Radford-Smith, Graham L., Visscher, Peter M., The International IBD Genetics Consortium, Australia and New Zealand IBDGC, Belgium Genetic Consortium, Initiative on Crohn and Colitis, NIDDK IBDGC, United Kingdom IBDGC and Wellcome Trust Case Control Consortium (2014). Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. Human Molecular Genetics, 23 (17) ddu174, 4710-4720. doi: 10.1093/hmg/ddu174

Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data

2014

Journal Article

A comparative study of techniques for differential expression analysis on RNA-seq data

Zhang, Zong Hong, Jhaveri, Dhanisha J., Marshall, Vikki M., Bauer, Denis C., Edson, Janette, Narayanan, Ramesh K., Robinson, Gregory J., Lundberg, Andreas E., Bartlett, Perry F., Wray, Naomi R. and Zhao, Qiong-Yi (2014). A comparative study of techniques for differential expression analysis on RNA-seq data. PLoS One, 9 (8) e103207, 1-11. doi: 10.1371/journal.pone.0103207

A comparative study of techniques for differential expression analysis on RNA-seq data

2014

Journal Article

The association between family history of mental disorders and general cognitive ability

McGrath, J. J., Wray, N. R., Pedersen, C. B., Mortensen, P. B., Greve, A. N. and Petersen, L. (2014). The association between family history of mental disorders and general cognitive ability. Translational Psychiatry, 4 (e412) e412, 1-6. doi: 10.1038/tp.2014.60

The association between family history of mental disorders and general cognitive ability

2014

Journal Article

Applying polygenic risk scores to postpartum depression

Byrne, Edna M., Carrillo-Roa, Tania, Penninx, Brenda W. J. H., Sallis, Hannah M., Viktorin, Alexander, Chapman, Brett, Henders, Anjali K., Pergadia, Michele L., Heath, Andrew C., Madden, Pamela A. F., Sullivan, Patrick F., Boschloo, Lynn, van Grootheest, Gerard, McMahon, George, Lawlor, Debbie A., Landen, Mikael, Lichtenstein, Paul, Magnusson, Patrik K. E., Evans, David M., Montgomery, Grant W., Boomsma, Dorret I., Martin, Nicholas G., Meltzer-Brody, Samantha and Wray, Naomi R. (2014). Applying polygenic risk scores to postpartum depression. Archives of Women's Mental Health, 17 (6), 519-528. doi: 10.1007/s00737-014-0428-5

Applying polygenic risk scores to postpartum depression

2014

Journal Article

Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood

McKenzie, Marna, Henders, Anjali K., Caracella, Anthony, Wray, Naomi R. and Powell, Joseph E. (2014). Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood. BMC Medical Genomics, 7 (1) 31, 1-11. doi: 10.1186/1755-8794-7-31

Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood

2014

Journal Article

Hypermethylation in the ZBTB20 gene is associated with major depressive disorder

Davies, Matthew N., Krause, Lutz, Bell, Jordana T., Gao, Fei, Ward, Kirsten J., Wu, Honglong, Lu, Hanlin, Liu, Yuan, Tsai, Pei-Chein, Collier, David A., Murphy, Therese, Dempster, Emma, Mill, Jonathan, UK Brain Expression Consortium, Battle, Alexis, Mostafavi, Sara, Zhu, Xiaowei, Henders, Anjali, Byrne, Enda, Wray, Naomi R., Martin, Nicholas G., Spector, Tim D. and Wang, Jun (2014). Hypermethylation in the ZBTB20 gene is associated with major depressive disorder. Genome Biology, 15 (4) R56, R56.1-R56.12. doi: 10.1186/gb-2014-15-4-r56

Hypermethylation in the ZBTB20 gene is associated with major depressive disorder

2014

Journal Article

Explaining additional genetic variation in complex traits

Robinson, Matthew R., Wray, Naomi R. and Visscher, Peter M. (2014). Explaining additional genetic variation in complex traits. Trends in Genetics, 30 (4), 124-132. doi: 10.1016/j.tig.2014.02.003

Explaining additional genetic variation in complex traits

2014

Journal Article

NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development

Piper, Michael, Barry, Guy, Harvey, Tracey J., McLeay, Robert, Smith, Aaron G., Harris, Lachlan, Mason, Sharon, Stringer, Brett W., Day, Bryan W., Wray, Naomi R., Gronostajski, Richard M., Bailey, Timothy L., Boyd, Andrew W. and Richards, Linda J. (2014). NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. Journal of Neuroscience, 34 (8), 2921-2930. doi: 10.1523/JNEUROSCI.2319-13.2014

NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development

2014

Journal Article

DNA modification study of major depressive disorder: beyond locus-by-locus comparisons

Oh, Gabriel, Wang, Sun-Chong, Pal, Mrinal, Chen, Zheng Fei, Khare, Tarang, Tochigi, Mamoru, Ng, Catherine, Yang, Yeqing A., Kwan, Andrew, Kaminsky, Zachary A., Mill, Jonathan, Gunasinghe, Cerisse, Tackett, Jennifer L., Gottesman, Irving I., Willemsen, Gonneke, de Geus, Eco J. C., Vink, Jacqueline M., Slagboom, P. Eline, Wray, Naomi R., Heath, Andrew C., Montgomery, Grant W., Turecki, Gustavo, Martin, Nicholas G., Boomsma, Dorret I., McGuffin, Peter, Kustra, Rafal and Petronis, Art (2014). DNA modification study of major depressive disorder: beyond locus-by-locus comparisons. Biological Psychiatry, 77 (3), 246-255. doi: 10.1016/j.biopsych.2014.06.016

DNA modification study of major depressive disorder: beyond locus-by-locus comparisons

2014

Journal Article

Research Review: Polygenic methods and their application to psychiatric traits

Wray, Naomi R., Lee, Sang Hong, Mehta, Divya, Vinkhuyzen, Anna A. E., Dudbridge, Frank and Middeldorp, Christel M. (2014). Research Review: Polygenic methods and their application to psychiatric traits. Journal of Child Psychology and Psychiatry, 55 (10), 1068-1087. doi: 10.1111/jcpp.12295

Research Review: Polygenic methods and their application to psychiatric traits