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2017

Journal Article

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Alda, M., Alliey-Rodriguez, N., Andreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S., Bethell, A., Biernacka, J. M. ... Rietschel, M. (2017). Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.. Translational psychiatry, 7 (6), e1155-e1155. doi: 10.1038/tp.2017.115

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

2017

Journal Article

Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity

McCombe, P. A., Wray, N. R. and Henderson, R. D. (2017). Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity. Expert Review of Neurotherapeutics, 17 (6), 561-577. doi: 10.1080/14737175.2017.1273772

Extra-motor abnormalities in amyotrophic lateral sclerosis: another layer of heterogeneity

2017

Journal Article

Maternal depression and family adversity: linked pathways to offspring depression?

Najman, Jake M., Plotnikova, M., Williams, G. M., Alati, R., Mamun, A. A., Scott, J., Clavarino, A. M. and Wray, N. (2017). Maternal depression and family adversity: linked pathways to offspring depression?. Journal of Psychiatric Research, 88, 97-104. doi: 10.1016/j.jpsychires.2017.01.006

Maternal depression and family adversity: linked pathways to offspring depression?

2017

Journal Article

Genetic signatures of high-altitude adaptation in Tibetans

Yang, Jian, Jin, Zi-Bing, Chen, Jie, Huang, Xiu-Feng, Li, Xiao-Man, Liang, Yuan-Bo, Mao, Jian-Yang, Chen, Xin, Zheng, Zhili, Bakshi, Andrew, Zheng, Dong-Dong, Zheng, Mei-Qin, Wray, Naomi R., Visscher, Peter M., Lu, Fan and Qu, Jia (2017). Genetic signatures of high-altitude adaptation in Tibetans. Proceedings of the National Academy of Sciences, 114 (16), 4189-4194. doi: 10.1073/pnas.1617042114

Genetic signatures of high-altitude adaptation in Tibetans

2017

Journal Article

Genetic effects influencing risk for major depressive disorder in China and Europe

Bigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A, Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschon, H. N., Byrne, E. M., Cichon, S., Clarke, T-K, Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F., Dunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P. ... Kendler, K. S. (2017). Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry, 7 (3) e1074, e1074-e1074. doi: 10.1038/tp.2016.292

Genetic effects influencing risk for major depressive disorder in China and Europe

2017

Journal Article

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

McLaughlin, Russell L., Schijven, Dick, Van Rheenen, Wouter, Van Eijk, Kriste R., O'Brien, Margaret, Kahn, Rene S., Ophoff, Roel A., Goris, An, Bradley, Daniel G., Al-Chalabi, Ammar, Van Den Berg, Leonard H., Luykx, Jurjen J., Hardiman, Orla, Veldink, Jan H., Project MinE GWAS Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M. and Mowry, Bryan J. (2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications, 8 (1) 14774, 14774. doi: 10.1038/ncomms14774

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

2017

Journal Article

Using information of relatives in genomic prediction to apply effective stratified medicine

Lee, S. Hong, Weerasinghe, W. M. Shalanee P., Wray, Naomi R., Goddard, Michael E. and Van Der Werf, Julius H. J. (2017). Using information of relatives in genomic prediction to apply effective stratified medicine. Scientific Reports, 7 (1) 42091, 42091. doi: 10.1038/srep42091

Using information of relatives in genomic prediction to apply effective stratified medicine

2017

Journal Article

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Gratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2017). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Obstetrical and Gynecological Survey, 72 (2), 96-96. doi: 10.1097/01.OGX.0000512485.13448.C7

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

2017

Journal Article

Trajectories of maternal depression: a 27-year population-based prospective study

Najman, J. M., Plotnikova, M., Williams, G. M., Alati, R., Mamun, A. A., Scott, J., Wray, N. and Clavarino, A. M. (2017). Trajectories of maternal depression: a 27-year population-based prospective study. Epidemiology and Psychiatric Sciences, 26 (1), 79-88. doi: 10.1017/S2045796015001109

Trajectories of maternal depression: a 27-year population-based prospective study

2017

Journal Article

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan, North, Kari, Sundstrom, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F., Harris, Sarah E., Gibson, Jude, Redmond, Paul, Corley, Janie ... Deary, Ian J. (2017). Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach. PLoS Medicine, 14 (1) e1002215, e1002215. doi: 10.1371/journal.pmed.1002215

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

2017

Conference Publication

Polygenic score methodology in psychiatric genetics

O'Reilly, Paul, Wray, Naomi and Breen, Gerome (2017). Polygenic score methodology in psychiatric genetics. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Polygenic score methodology in psychiatric genetics

2017

Conference Publication

Characterizing an inverse axis between orthogonal sources of genetic risk

Davis, Lea, Lee, Sang Hong, Gamazon, Eric, Im, Hae Kyung, Yu, Dongmei, McGrath, Lauren, Williams, Stephanie, Cook, Edwin, Sullivan, Patrick, Sutcliffe, James, Knowles, James, Mathews, Carol, Scharf, Jeremiah, Wray, Naomi and Cox, Nancy (2017). Characterizing an inverse axis between orthogonal sources of genetic risk. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Characterizing an inverse axis between orthogonal sources of genetic risk

2017

Conference Publication

The potential impact of falsely classified controls on the SNP-based heritability of depression

Peyrot, Wouter J., Penninx, Brenda and Wray, Naomi (2017). The potential impact of falsely classified controls on the SNP-based heritability of depression. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

The potential impact of falsely classified controls on the SNP-based heritability of depression

2017

Conference Publication

Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Maier, Robert, Wray, Naomi, Robinson, Matt and Lee, Sang Hong (2017). Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

2017

Conference Publication

Genetic architecture insights from joint investigations of rare CNVS and common SNPS

Bergen, Sarah, Kendler, Kenneth and Wray, Naomi (2017). Genetic architecture insights from joint investigations of rare CNVS and common SNPS. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Genetic architecture insights from joint investigations of rare CNVS and common SNPS

2017

Journal Article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, Christian R., Howrigan, Daniel P., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wu, Wenting, Greer, Douglas S., Antaki, Danny, Shetty, Aniket, Holmans, Peter A., Pinto, Dalila, Gujral, Madhusudan, Brandler, William M., Malhotra, Dheeraj, Wang, Zhouzhi, Fuentes Fajarado, Karin V., Maile, Michelle S., Ripke, Stephan, Agartz, Ingrid, Albus, Margot, Alexander, Madeline, Amin, Farooq, Atkins, Joshua, Bacanu, Silviu A., Belliveau, Richard A., Jr., Bergen, Sarah E., Bertalan, Marcelo, Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W. ... Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 49 (1), 27-35. doi: 10.1038/ng.3725

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

2017

Conference Publication

Multivariate genetic risk scores increase accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Maier, Robert, Wray, Naomi and Lee, Sang Hong (2017). Multivariate genetic risk scores increase accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Multivariate genetic risk scores increase accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

2017

Conference Publication

Evidence for genetic overlap between schizophrenia and maternal age at first birth

Mehta, Divya, Tropf, Felix, Gratten, Jacob, Bacanu, Silviu, Bakshi, Andrew, Mowry, Bryan, Kendler, Kenneth, Yang, Jian, Visscher, Peter, McGrath, John, Mills, Melinda, Wray, Naomi and Lee, Sang Hong (2017). Evidence for genetic overlap between schizophrenia and maternal age at first birth. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, ON, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2015.09.010

Evidence for genetic overlap between schizophrenia and maternal age at first birth

2017

Conference Publication

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

2017

Conference Publication

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans

Vinkhuyzen, Anna, John, Sujit, Periyasamy, Sathish, Wray, Naomi, Thara, Rangaswamy and Mowry, Bryan (2017). Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans