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2017 Conference Publication Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with EuropeansVinkhuyzen, Anna, John, Sujit, Periyasamy, Sathish, Wray, Naomi, Thara, Rangaswamy and Mowry, Bryan (2017). Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication High loading of polygenic risk in cases with chronic schizophreniaMeier, Sandra, Agerbo, Esben, Maier, Robert, Pedersen, Carsten B., Lang, Maren, Ripke, Stephan, Werge, Thomas, Mors, Ole, Hougaard, David, Borglum, Anders, Wray, Naomi, Rietschel, Marcella, Nordentoft, Merete, Mortensen, Preben Bo and Mattheisen, Manuel (2017). High loading of polygenic risk in cases with chronic schizophrenia. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication Polygenic score methodology in psychiatric geneticsO'Reilly, Paul, Wray, Naomi and Breen, Gerome (2017). Polygenic score methodology in psychiatric genetics. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication Characterizing an inverse axis between orthogonal sources of genetic riskDavis, Lea, Lee, Sang Hong, Gamazon, Eric, Im, Hae Kyung, Yu, Dongmei, McGrath, Lauren, Williams, Stephanie, Cook, Edwin, Sullivan, Patrick, Sutcliffe, James, Knowles, James, Mathews, Carol, Scharf, Jeremiah, Wray, Naomi and Cox, Nancy (2017). Characterizing an inverse axis between orthogonal sources of genetic risk. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication The potential impact of falsely classified controls on the SNP-based heritability of depressionPeyrot, Wouter J., Penninx, Brenda and Wray, Naomi (2017). The potential impact of falsely classified controls on the SNP-based heritability of depression. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorderMaier, Robert, Wray, Naomi, Robinson, Matt and Lee, Sang Hong (2017). Multivariate polygenic risk scores increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2017 Conference Publication Genetic architecture insights from joint investigations of rare CNVS and common SNPSBergen, Sarah, Kendler, Kenneth and Wray, Naomi (2017). Genetic architecture insights from joint investigations of rare CNVS and common SNPS. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. |
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2016 Journal Article Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorderZeng, Yanni, Navarro, Pau, Shirali, Masoud, Howard, David M., Adams, Mark J., Hall, Lynsey S., Clarke, Toni-Kim, Thomson, Pippa A., Smith, Blair H., Murray, Alison, Padmanabhan, Sandosh, Hayward, Caroline, Boutin, Thibaud, MacIntyre, Donald J., Lewis, Cathryn M., Wray, Naomi R., Mehta, Divya, Penninx, Brenda W. J. H., Milaneschi, Yuri, Baune, Bernhard T., Air, Tracy, Hottenga, Jouke-Jan, Mbarek, Hamdi, Castelao, Enrique, Pistis, Giorgio, Schulze, Thomas G., Streit, Fabian, Forstner, Andreas J., Byrne, Enda M. ... McIntosh, Andrew M. (2016). Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with major depressive disorder. Biological Psychiatry, 82 (5), 312-321. doi: 10.1016/j.biopsych.2016.12.012 |
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2016 Journal Article A DNA methylation biomarker of alcohol consumptionLiu, C., Marioni, R. E., Hedman, K., Pfeiffer, L., Tsai, P. -C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C., Mendelson, M. M., Joehanes, R., Liang, L., Love, S. -A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H. ... Levy, D. (2016). A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry, 23 (2), 422-433. doi: 10.1038/mp.2016.192 |
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2016 Journal Article Exploring boundaries for the genetic consequences of assortative mating for psychiatric traitsPeyrot, Wouter J., Robinson, Matthew R., Penninx, Brenda W. J. H. and Wray, Naomi R. (2016). Exploring boundaries for the genetic consequences of assortative mating for psychiatric traits. JAMA Psychiatry, 73 (11), 1189-1195. doi: 10.1001/jamapsychiatry.2016.2566 |
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2016 Journal Article No reliable association between runs of homozygosity and schizophrenia in a well-powered replication studyJohnson, Emma C., Bjelland, Douglas W., Howrigan, Daniel P., Abdellaoui, Abdel, Breen, Gerome, Borglum, Anders, Cichon, Sven, Degenhardt, Franziska, Forstner, Andreas J., Frank, Josef, Genovese, Giulio, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffman, Per, Maier, Wolfgang, Mattheisen, Manuel, Morris, Derek, Mowry, Bryan, Muller-Mhysok, Betram, Neale, Benjamin, Nenadic, Igor, Nothen, Markus M., O'Dushlaine, Colm, Rietschel, Marcella, Ruderfer, Douglas M., Rujescu, Dan, Schulze, Thomas G., Simonson, Matthew A., Stahl, Eli ... Keller, Matthew C. (2016). No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study. PLoS Genetics, 12 (10) e1006343, e1006343. doi: 10.1371/journal.pgen.1006343 |
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2016 Journal Article Epigenetic signatures of cigarette smokingJoehanes, Roby, Just, Allan C., Marioni, Riccardo E., Pilling, Luke C., Reynolds, Lindsay M., Mandaviya, Pooja R., Guan, Weihua, Xu, Tao, Elks, Cathy E., Aslibekyan, Stella, Moreno-Macias, Hortensia, Smith, Jennifer A., Brody, Jennifer A., Dhingra, Radhika, Yousefi, Paul, Pankow, James S., Kunze, Sonja, Shah, Sonia H., McRae, Allan F., Lohman, Kurt, Sha, Jin, Absher, Devin M., Ferrucci, Luigi, Zhao, Wei, Demerath, Ellen W., Bressler, Jan, Grove, Megan L., Huan, Tianxiao, Liu, Chunyu ... London, Stephanie J. (2016). Epigenetic signatures of cigarette smoking. Circulation: Cardiovascular Genetics, 9 (5), 436-447. doi: 10.1161/CIRCGENETICS.116.001506 |
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2016 Journal Article Meta-analysis of genome-wide association studies of anxiety disordersOtowa, T., Hek, K., Lee, M., Byrne, E. M., Mirza, S. S., Nivard, M. G., Bigdeli, T., Aggen, S. H., Adkins, D., Wolen, A., Fanous, A., Keller, M. C., Castelao, E., Kutalik, Z., Der Auwera, S. V., Homuth, G., Nauck, M., Teumer, A., Milaneschi, Y., Hottenga, J. -J., Direk, N., Hofman, A., Uitterlinden, A., Mulder, C. L., Henders, A. K., Medland, S. E., Gordon, S., Heath, A. C., Madden, P. A. F. ... Hettema, J. M. (2016). Meta-analysis of genome-wide association studies of anxiety disorders. Molecular Psychiatry, 21 (10), 1391-1399. doi: 10.1038/mp.2015.197 |
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2016 Journal Article Concepts and misconceptions about the polygenic additive model applied to diseaseVisscher, Peter M. and Wray, Naomi R. (2016). Concepts and misconceptions about the polygenic additive model applied to disease. Human Heredity, 80 (4), 165-170. doi: 10.1159/000446931 |
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2016 Journal Article Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosisvan Rheenen, Wouter, Shatunov, Aleksey, Dekker, Annelot M., McLaughlin, Russell L., Diekstra, Frank P., Pulit, Sara L., van der Spek, Rick A. A., Vosa, Urmo, de Jong, Simone, Robinson, Matthew R., Yang, Jian, Fogh, Isabella, van Doormaal, Perry T. C., Tazelaar, Gijs H. P., Koppers, Max, Blokhuis, Anna M., Sproviero, William, Jones, Ashley R., Kenna, Kevin P., van Eijk, Kristel R., Harschnitz, Oliver, Schellevis, Raymond D., Brands, William J., Medic, Jelena, Menelaou, Androniki, Vajda, Alice, Ticozzi, Nicola, Lin, Kuang, Rogelj, Boris ... Veldink, Jan H. (2016). Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nature Genetics, 48 (9) 611, 1043-1048. doi: 10.1038/ng.3622 |
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2016 Journal Article Across-cohort QC analyses of GWAS summary statistics from complex traitsChen, Guo-Bo, Lee, Sang Hong, Robinson, Matthew R., Trzaskowski, Maciej, Zhu, Zhi-Xiang, Winkler, Thomas W., Day, Felix R., Croteau-Chonka, Damien C., Wood, Andrew R., Locke, Adam E., Kutalik, Zoltán, Loos, Ruth J. F., Frayling, Timothy M., Hirschhorn, Joel N., Yang, Jian, Wray, Naomi R. and Visscher, Peter M. (2016). Across-cohort QC analyses of GWAS summary statistics from complex traits. European Journal of Human Genetics, 25 (1), 137-146. doi: 10.1038/ejhg.2016.106 |
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2016 Journal Article GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPsYang, Jian, Lee, S. Hong, Wray, Naomi R., Goddard, Michael E. and Visscher, Peter M. (2016). GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs. Proceedings of the National Academy of Sciences, 113 (32), E4579-E4580. doi: 10.1073/pnas.1602743113 |
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2016 Journal Article Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traitsPavlides, Jennifer M. Whitehead, Zhu, Zhihong, Gratten, Jacob, Mcrae, Allan F., Wray, Naomi R. and Yang, Jian (2016). Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Medicine, 8 (1) 84, 84. doi: 10.1186/s13073-016-0338-4 |
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2016 Journal Article A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseasesHan, Buhm, Pouget, Jennie G., Slowikowski, Kamil, Stahl, Eli, Lee, Cue Hyunkyu, Diogo, Dorothee, Hu, Xinli, Park, Yu Rang, Kim, Eunji, Gregersen, Peter K., Dahlqvist, Solbritt Rantapaa, Worthington, Jane, Martin, Javier, Eyre, Steve, Klareskog, Lars, Huizinga, Tom, Chen, Wei-Min, Onengut-Gumuscu, Suna, Rich, Stephen S., Wray, Naomi R. and Raychaudhuri, Soumya (2016). A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. Nature Genetics, 48 (7), 803-810. doi: 10.1038/ng.3572 |
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2016 Journal Article Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analysesOkbay, Aysu, Baselmans, Bart M. L., De Neve, Jan-Emmanuel, Turley, Patrick, Nivard, Michel G., Fontana, Mark Alan, Meddens, S. Fleur W., Linner, Richard Karlsson, Rietveld, Cornelius A., Derringer, Jaime, Gratten, Jacob, Lee, James J., Liu, Jimmy Z., de Vlaming, Ronald, Ahluwalia, Tarunveer S., Buchwald, Jadwiga, Cavadino, Alana, Frazier-Wood, Alexis C., Furlotte, Nicholas A., Garfield, Victoria, Geisel, Marie Henrike, Gonzalez, Juan R., Haitjema, Saskia, Karlsson, Robert, van der Laan, Sander W., Ladwig, Karl-Heinz, Lahti, Jari, van der Lee, Sven J., Lind, Penelope A. ... Cesarini, David (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics, 48 (6), 624-633. doi: 10.1038/ng.3552 |
