Skip to menu Skip to content Skip to footer

2014

Journal Article

Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data

Chen, Guo-Bo, Lee, Sang Hong, Brion, Marie-Jo A., Montgomery, Grant W., Wray, Naomi R., Radford-Smith, Graham L., Visscher, Peter M., The International IBD Genetics Consortium, Australia and New Zealand IBDGC, Belgium Genetic Consortium, Initiative on Crohn and Colitis, NIDDK IBDGC, United Kingdom IBDGC and Wellcome Trust Case Control Consortium (2014). Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. Human Molecular Genetics, 23 (17) ddu174, 4710-4720. doi: 10.1093/hmg/ddu174

Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data

2014

Journal Article

A comparative study of techniques for differential expression analysis on RNA-seq data

Zhang, Zong Hong, Jhaveri, Dhanisha J., Marshall, Vikki M., Bauer, Denis C., Edson, Janette, Narayanan, Ramesh K., Robinson, Gregory J., Lundberg, Andreas E., Bartlett, Perry F., Wray, Naomi R. and Zhao, Qiong-Yi (2014). A comparative study of techniques for differential expression analysis on RNA-seq data. PLoS One, 9 (8) e103207, 1-11. doi: 10.1371/journal.pone.0103207

A comparative study of techniques for differential expression analysis on RNA-seq data

2014

Journal Article

The association between family history of mental disorders and general cognitive ability

McGrath, J. J., Wray, N. R., Pedersen, C. B., Mortensen, P. B., Greve, A. N. and Petersen, L. (2014). The association between family history of mental disorders and general cognitive ability. Translational Psychiatry, 4 (e412) e412, 1-6. doi: 10.1038/tp.2014.60

The association between family history of mental disorders and general cognitive ability

2014

Journal Article

Applying polygenic risk scores to postpartum depression

Byrne, Edna M., Carrillo-Roa, Tania, Penninx, Brenda W. J. H., Sallis, Hannah M., Viktorin, Alexander, Chapman, Brett, Henders, Anjali K., Pergadia, Michele L., Heath, Andrew C., Madden, Pamela A. F., Sullivan, Patrick F., Boschloo, Lynn, van Grootheest, Gerard, McMahon, George, Lawlor, Debbie A., Landen, Mikael, Lichtenstein, Paul, Magnusson, Patrik K. E., Evans, David M., Montgomery, Grant W., Boomsma, Dorret I., Martin, Nicholas G., Meltzer-Brody, Samantha and Wray, Naomi R. (2014). Applying polygenic risk scores to postpartum depression. Archives of Women's Mental Health, 17 (6), 519-528. doi: 10.1007/s00737-014-0428-5

Applying polygenic risk scores to postpartum depression

2014

Journal Article

Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood

McKenzie, Marna, Henders, Anjali K., Caracella, Anthony, Wray, Naomi R. and Powell, Joseph E. (2014). Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood. BMC Medical Genomics, 7 (1) 31, 1-11. doi: 10.1186/1755-8794-7-31

Overlap of expression Quantitative Trait Loci (eQTL) in human brain and blood

2014

Journal Article

Hypermethylation in the ZBTB20 gene is associated with major depressive disorder

Davies, Matthew N., Krause, Lutz, Bell, Jordana T., Gao, Fei, Ward, Kirsten J., Wu, Honglong, Lu, Hanlin, Liu, Yuan, Tsai, Pei-Chein, Collier, David A., Murphy, Therese, Dempster, Emma, Mill, Jonathan, UK Brain Expression Consortium, Battle, Alexis, Mostafavi, Sara, Zhu, Xiaowei, Henders, Anjali, Byrne, Enda, Wray, Naomi R., Martin, Nicholas G., Spector, Tim D. and Wang, Jun (2014). Hypermethylation in the ZBTB20 gene is associated with major depressive disorder. Genome Biology, 15 (4) R56, R56.1-R56.12. doi: 10.1186/gb-2014-15-4-r56

Hypermethylation in the ZBTB20 gene is associated with major depressive disorder

2014

Journal Article

Explaining additional genetic variation in complex traits

Robinson, Matthew R., Wray, Naomi R. and Visscher, Peter M. (2014). Explaining additional genetic variation in complex traits. Trends in Genetics, 30 (4), 124-132. doi: 10.1016/j.tig.2014.02.003

Explaining additional genetic variation in complex traits

2014

Journal Article

NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development

Piper, Michael, Barry, Guy, Harvey, Tracey J., McLeay, Robert, Smith, Aaron G., Harris, Lachlan, Mason, Sharon, Stringer, Brett W., Day, Bryan W., Wray, Naomi R., Gronostajski, Richard M., Bailey, Timothy L., Boyd, Andrew W. and Richards, Linda J. (2014). NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. Journal of Neuroscience, 34 (8), 2921-2930. doi: 10.1523/JNEUROSCI.2319-13.2014

NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development

2014

Journal Article

DNA modification study of major depressive disorder: beyond locus-by-locus comparisons

Oh, Gabriel, Wang, Sun-Chong, Pal, Mrinal, Chen, Zheng Fei, Khare, Tarang, Tochigi, Mamoru, Ng, Catherine, Yang, Yeqing A., Kwan, Andrew, Kaminsky, Zachary A., Mill, Jonathan, Gunasinghe, Cerisse, Tackett, Jennifer L., Gottesman, Irving I., Willemsen, Gonneke, de Geus, Eco J. C., Vink, Jacqueline M., Slagboom, P. Eline, Wray, Naomi R., Heath, Andrew C., Montgomery, Grant W., Turecki, Gustavo, Martin, Nicholas G., Boomsma, Dorret I., McGuffin, Peter, Kustra, Rafal and Petronis, Art (2014). DNA modification study of major depressive disorder: beyond locus-by-locus comparisons. Biological Psychiatry, 77 (3), 246-255. doi: 10.1016/j.biopsych.2014.06.016

DNA modification study of major depressive disorder: beyond locus-by-locus comparisons

2014

Journal Article

Large-scale genomics unveils the genetic architecture of psychiatric disorders

Gratten, Jacob, Wray, Naomi R., Keller, Matthew C. and Visscher, Peter M. (2014). Large-scale genomics unveils the genetic architecture of psychiatric disorders. Nature Neuroscience, 17 (6), 782-790. doi: 10.1038/nn.3708

Large-scale genomics unveils the genetic architecture of psychiatric disorders

2014

Journal Article

A recessive genetic model and runs of homozygosity in major depressive disorder

Power, Robert A., Keller, Matthew C., Ripke, Stephan, Abdellaoui, Abdel, Wray, Naomi R., Sullivan, Patrick F. and Breen, Gerome (2014). A recessive genetic model and runs of homozygosity in major depressive disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 165 (2), 157-166. doi: 10.1002/ajmg.b.32217

A recessive genetic model and runs of homozygosity in major depressive disorder

2014

Journal Article

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E. and Yang, Jian (2014). Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples. PLoS Genetics, 10 (4) e1004269, e1004269.1-e1004269.10. doi: 10.1371/journal.pgen.1004269

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

2014

Journal Article

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M., Mowry, Bryan J., Nertney, Deborah A., Psychosis Endophenotypes International Consortium and Wellcome Trust Case-Control Consortium 2 (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511 (7510), 421-427. doi: 10.1038/nature13595

Biological insights from 108 schizophrenia-associated genetic loci

2014

Journal Article

Association of OPRD1 polymorphisms with heroin dependence in a large case-control series

Nelson, Elliot C., Lynskey, Michael T., Heath, Andrew C., Wray, Naomi, Agrawal, Arpana, Shand, Fiona L., Henders, Anjali K., Wallace, Leanne, Todorov, Alexandre A., Schrage, Andrew J., Madden, Pamela A. F., Degenhardt, Louisa, Martin, Nicholas G. and Montgomery, Grant W. (2014). Association of OPRD1 polymorphisms with heroin dependence in a large case-control series. Addiction Biology, 19 (1), 111-121. doi: 10.1111/j.1369-1600.2012.00445.x

Association of OPRD1 polymorphisms with heroin dependence in a large case-control series

2014

Journal Article

Testing the role of circadian genes in conferring risk for psychiatric disorders

Byrne, Enda M., Heath, Andrew C., Madden, Pamela A. F., Pergadia, Michele L., Hickie, Ian B., Montgomery, Grant W., Martin, Nicholas G. and Wray, Naomi R. (2014). Testing the role of circadian genes in conferring risk for psychiatric disorders. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 165 (3), 254-260. doi: 10.1002/ajmg.b.32230

Testing the role of circadian genes in conferring risk for psychiatric disorders

2014

Book Chapter

Future directions in genetics of psychiatric disorders

Wray, Naomi R., Byrne, Enda M., Stringer, Sven and Mowry, Bryan J. (2014). Future directions in genetics of psychiatric disorders. Behavior genetics of psychopathology. (pp. 311-337) edited by Soo Hyun Rhee and Angelica Ronald. New York, NY, United States: Springer New York. doi: 10.1007/978-1-4614-9509-3_11

Future directions in genetics of psychiatric disorders

2014

Journal Article

Genetic predisposition to schizophrenia associated with increased use of cannabis

Power, R. A., Verweij, K. J. H., Zuhair, M., Montgomery, G. W., Henders, A. K., Heath, A. C., Madden, P. A. F., Medland, S. E., Wray, N. R. and Martin, N. G. (2014). Genetic predisposition to schizophrenia associated with increased use of cannabis. Molecular Psychiatry, 19 (11), 1201-1204. doi: 10.1038/mp.2014.51

Genetic predisposition to schizophrenia associated with increased use of cannabis

2014

Journal Article

Research Review: Polygenic methods and their application to psychiatric traits

Wray, Naomi R., Lee, Sang Hong, Mehta, Divya, Vinkhuyzen, Anna A. E., Dudbridge, Frank and Middeldorp, Christel M. (2014). Research Review: Polygenic methods and their application to psychiatric traits. Journal of Child Psychology and Psychiatry, 55 (10), 1068-1087. doi: 10.1111/jcpp.12295

Research Review: Polygenic methods and their application to psychiatric traits

2013

Journal Article

A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability

Derks, Eske M., Ayub, Muhammad, Chambert, Kimberly, Del Favero, Jurgen, Johnstone, Mandy, Macgregor, Stuart, Maclean, Alan, McKechanie, Andrew G., McRae, Allan F., Moran, Jennifer L., Pickard, Benjamin S., Purcell, Shaun, Sklar, Pamela, St Clair, David M., Wray, Naomi R., Visscher, Peter M. and Blackwood, Douglas H. R. (2013). A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 162 (8), 847-854. doi: 10.1002/ajmg.b.32189

A genome wide survey supports the involvement of large copy number variants in schizophrenia with and without intellectual disability

2013

Journal Article

Author reply to A commentary on Pitfalls of predicting complex traits from SNPs

Wray, Naomi R., Yang, Jian, Hayes, Ben J., Price, Alkes L., Goddard, Michael E. and Visscher, Peter M. (2013). Author reply to A commentary on Pitfalls of predicting complex traits from SNPs. Nature Reviews Genetics, 14 (12), 894-894. doi: 10.1038/nrg3457-c2

Author reply to A commentary on Pitfalls of predicting complex traits from SNPs