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2013 Journal Article Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic ArchitectureDavis, Lea K., Yu, Dongmei, Keenan, Clare L., Gamazon, Eric R., Konkashbaev, Anuar I., Derks, Eske M., Neale, Benjamin M., Yang, Jian, Lee, S. Hong, Evans, Patrick, Barr, Cathy L., Bellodi, Laura, Benarroch, Fortu, Berrio, Gabriel Bedoya, Bienvenu, Oscar J., Bloch, Michael H., Blom, Rianne M., Bruun, Ruth D., Budman, Cathy L., Camarena, Beatriz, Campbell, Desmond, Cappi, Carolina, Cardona Silgado, Julio C., Cath, Danielle C., Cavallini, Maria C., Chavira, Denise A., Chouinard, Sylvain, Conti, David V, Cook, Edwin H ... Scharf, Jeremiah M. (2013). Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture. PLoS Genetics, 9 (10) e1003864, e1003864.1-e1003864.14. doi: 10.1371/journal.pgen.1003864 |
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2013 Journal Article Estimation of SNP heritability from dense genotype dataLee, S. Hong, Yang, Jian, Chen, Guo-Bo, Ripke, Stephan, Stahl, Eli A., Hultman, Christina M., Sklar, Pamela, Visscher, Peter M., Sullivan, Patrick F., Goddard, Michael E. and Wray, Naomi (2013). Estimation of SNP heritability from dense genotype data. American Journal Of Human Genetics, 93 (6), 1151-1155. doi: 10.1016/j.ajhg.2013.10.015 |
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2013 Journal Article Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome-wide association study of both common and rare variantsYang, Li, Neale, Benjamin M., Liu, Lu, Lee, S. Hong, Wray, Naomi R., Ji, Ning, Li, Haimei, Qian, Qiujin, Wang, Dongliang, Li, Jun, Faraone, Stephen V. and Wang, Yufeng (2013). Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: Genome-wide association study of both common and rare variants. American Journal of Medical Genetics, Part B, Neuropsychiatric Genetics, 162 (5), 419-430. doi: 10.1002/ajmg.b.32169 |
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2012 Conference Publication Additive genetic variation in risk to schizophrenia across African American and European American populationsde Candia, Teresa, Lee, Hong, Yang, Jian, Browning, Brian, Gejman, Pablo, Levinson, Douglas, Hewitt, John, Visscher, Peter, Wray, Naomi and Keller, Matthew (2012). Additive genetic variation in risk to schizophrenia across African American and European American populations. 42nd Annual Meeting of the Behavior-Genetics-Association, Edinburgh Scotland, Jun 22-25, 2012. |
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2012 Journal Article Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorderLee, P. H., Perlis, R. H., Jung, J-Y, Byrne, E. M., Rueckert, E., Siburian, R., Haddad, S., Mayerfeld, C. E., Heath, A. C., Pergadia, M. L., Madden, P. A. F., Boomsma, D. I., Penninx, B. W., Sklar, P., Martin, N. G., Wray, N. R., Purcell, S. M. and Smoller, J. W. (2012). Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Translational Psychiatry, 2 (11) e184, e184.1-e184.9. doi: 10.1038/tp.2012.95 |
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2012 Journal Article Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihoodLee, S. H., Yang, J., Goddard, M. E., Visscher, P. M. and Wray, N. R. (2012). Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood. Bioinformatics, 28 (19) bts474, 2540-2542. doi: 10.1093/bioinformatics/bts474 |
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2012 Journal Article Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association studyTielbeek, Jorim J., Medland, Sarah E., Benyamin, Beben, Byrne, Enda M., Heath, Andrew C., Madden, Pamela A. F., Martin, Nicholas G., Wray, Naomi R. and Verweij, Karin J. H. (2012). Unraveling the genetic etiology of adult antisocial behavior: a genome-wide association study. PLoS One, 7 (10) e45086, e1005378-e1005378. doi: 10.1371/journal.pone.0045086 |
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2012 Journal Article Appraisals of stressful life events as a genetically-linked mechanism in the stress-depression relationshipConway, Christopher C., Hammen, Constance, Espejo, Emmanuel P., Wray, Naomi R., Najman, Jake M. and Brennan, Patricia A. (2012). Appraisals of stressful life events as a genetically-linked mechanism in the stress-depression relationship. Cognitive Therapy and Research, 36 (4), 338-347. doi: 10.1007/s10608-011-9368-9 |
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2012 Journal Article Using summary data from the Danish National Registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorderWray, Naomi R. and Gottesman, Irving I. (2012). Using summary data from the Danish National Registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. Frontiers in Applied Genetic Epidemiology, 3 (118) Article 118, 118. doi: 10.3389/fgene.2012.00118 |
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2012 Journal Article Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (vol 44, pg 247, 2012)Lee, S. Hong, DeCandia, Teresa R., Ripke, Stephan, Yang, Jian, Sullivan, Patrick F., Goddard, Michael E., Keller, Matthew C., Visscher, Peter M. and Wray, Naomi R. (2012). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (vol 44, pg 247, 2012). Nature Genetics, 44 (7), 831-831. doi: 10.1038/ng0712-831a |
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2012 Journal Article Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypesWray, Naomi R., Lee, Sang Hong and Kendler, Kenneth S. (2012). Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes. European Journal of Human Genetics, 20 (6), 668-674. doi: 10.1038/ejhg.2011.257 |
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2012 Journal Article Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012)Vinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012). Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion (vol 2, e125, 2012). Translational Psychiatry, 2 (5) e125, e125-e125. doi: 10.1038/tp.2012.49 |
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2012 Journal Article A genome-wide meta-analysis of association studies of Cloninger's Temperament ScalesService, S. K., Verweij, K. J. H., Lahti, J., Congdon, E., Ekelund, J., Hintsanen, M., Raikkonen, K., Lehtimaki, T., Kahonen, M., Widen, E., Taanila, A., Veijola, J., Heath, A. C., Madden, P. A. F., Montgomery, G. W., Sabatti, C., Jarvelin, M-R, Palotie, A., Raitakari, O., Viikari, J., Martin, N. G., Eriksson, J. G., Keltikangas-Jarvinen, L., Wray, N. R. and Freimer, N. B. (2012). A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. Translational Psychiatry, 2 (5) e116, e116-e116. doi: 10.1038/tp.2012.37 |
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2012 Journal Article Meta-analyses of genome-wide linkage scans of anxiety-related phenotypesWebb, Bradley T., Guo, An-Yuan, Maher, Brion S., Zhao, Zhongming, van den Oord, Edwin J., Kendler, Kenneth S., Riley, Brien P., Gillespie, Nathan A., Prescott, Carol A., Middeldorp, Christel M., Willemsen, Gonneke, de Geus, Eco J. C., Hottenga, Jouke-Jan, Boomsma, Dorret I., Slagboom, Eline P., Wray, Naomi R., Montgomery, Grant W., Martin, Nicholas G., Wright, Margie J., Heath, Andrew C., Madden, Pamela A., Gelernter, Joel, Knowles, James A., Hamilton, Steven P., Weissman, Myrna M., Fyer, Abby J., Huezo-Diaz, Patricia, McGuffin, Peter, Farmer, Anne ... Hettema, John M. (2012). Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes. European Journal of Human Genetics, 20 (10), 1078-1084. doi: 10.1038/ejhg.2012.47 |
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2012 Journal Article A better coefficient of determination for genetic profile analysisLee, Sang Hong, Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2012). A better coefficient of determination for genetic profile analysis. Genetic Epidemiology, 36 (3), 214-224. doi: 10.1002/gepi.21614 |
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2012 Journal Article Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversionVinkhuyzen, A. A. E., Pedersen, N. L., Yang, J., Lee, S. H., Magnusson, P. K. E., Iacono, W. G., McGue, M., Madden, P. A. F., Heath, A. C., Luciano, M., Payton, A., Horan, M., Ollier, W., Pendleton, N., Deary, I. J., Montgomery, G. W., Martin, N. G., Visscher, P. M. and Wray, N. R. (2012). Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion. Translational Psychiatry, 2 (e102) 201227, e102-e102. doi: 10.1038/tp.2012.27 |
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2012 Journal Article Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPsLee, S. Hong, DeCandia, Teresa R., Ripke, Stephan, Yang, Jian, Sullivan, Patrick F ., Goddard, Michael E ., Keller, Matthew C ., Visscher, Peter M ., Wray, Naomi R., Schizophrenia Psychiat Genome-Wide, Int Schizophrenia Consortium ISC, Mol Genetics Schizophrenia and Mowry, Bryan (2012). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nature Genetics, 44 (3), 247-250. doi: 10.1038/ng.1108 |
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2012 Journal Article A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophreniaJia, Peilin, Wang, Lily, Fanous, Ayman H., Chen, Xiangning, Kendler, Kenneth S., Zhao, Zhongming, Morris, Derek W., O'Dushlaine, Colm T., Kenny, Elaine, Quinn, Emma M., Gill, Michael, Corvin, Aiden, O'Donovan, Michael C., Kirov, George K., Craddock, Nick J., Holmans, Peter A., Williams, Nigel M., Georgieva, Lucy, Nikolov, Ivan, Norton, N., Williams, H., Toncheva, Draga, Milanova, Vihra, Owen, Michael J., Hultman, Christina M., Lichtenstein, Paul, Thelander, Emma F., Sullivan, Patrick, McQuillin, Andrew ... Sklar, Pamela (2012). A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. Journal of Medical Genetics, 49 (2), 96-103. doi: 10.1136/jmedgenet-2011-100397 |
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2012 Journal Article Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypothesesVisscher, Peter, Goddard, M. E., Derks, E. M. and Wray, Naomi (2012). Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses. Molecular Psychiatry, 17 (5), 474-485. doi: 10.1038/mp.2011.65 |
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2012 Journal Article Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learnedWray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., Ripke, S., MacIntyre, D. J., McGhee, K. A., MacLean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., De Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., Van Den Oord, E. J. C. G., Liu, J. Z., MacGregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G. ... Sullivan, P. F. (2012). Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned. Molecular Psychiatry, 17 (1), 36-48. doi: 10.1038/mp.2010.109 |
