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2009 Journal Article Metal clips that induce unstructured pentapeptides to be alpha-Helical in waterMa, Michelle T., Hoang, Huy N., Scully, Conor C. G., Appleton, Trevor G. and Fairlie, David P. (2009). Metal clips that induce unstructured pentapeptides to be alpha-Helical in water. Journal of the American Chemical Society, 131 (12), 4505-4512. doi: 10.1021/ja900047w |
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2009 Journal Article The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitisCantley, M. D., Bartold, P. M., Marino, V, Reid, R. C., Fairlie, D. P., Wyszynski, R. N., Zilm, P. S. and Haynes, D. R. (2009). The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A(2) inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis. Journal of Periodontal Research, 44 (3), 317-322. doi: 10.1111/j.1600-0765.2008.01132.x |
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2009 Journal Article Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformationRobin, Gautier, Chappell, Keith, Stoermer, Martin J., Hu, Shu-Hong, Young, Paul R., Fairlie, David P. and Martin, Jennifer L. (2009). Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation. Journal of Molecular Biology, 385 (5), 1568-1577. doi: 10.1016/j.jmb.2008.11.026 |
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2009 Journal Article Targeting histone deacetylase inhibitors for anti-malarial therapyAndrews, K. T, Tran, T. N., Wheatley, N. and Fairlie, David (2009). Targeting histone deacetylase inhibitors for anti-malarial therapy. Current Topics in Medicinal Chemistry, 9 (3), 292-308. doi: 10.2174/156802609788085313 |
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2009 Journal Article Histone deacetylase inhibitors in inflammatory diseaseHalili, M. A., Andrews, M, Sweet, M. and Fairlie, D. P. (2009). Histone deacetylase inhibitors in inflammatory disease. Current Topics in Medicinal Chemistry, 9 (3), 309-319. doi: 10.2174/156802609788085250 |
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2009 Journal Article Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activationHalili, Maria A., Ruiz-Gomez, Gloria, Le, Giang T., Abbenante, Giovanni and Fairlie, David P. (2009). Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. Biochemistry, 48 (35), 8466-8472. doi: 10.1021/bi900679r |
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2009 Conference Publication Regulating protein and peptide activated GPCRsFairlie, David P., Madala, Praveen K., Stoermer, Martin J., Suen, Jacky, Barry, Grant and Lohman, Rink-Jan (2009). Regulating protein and peptide activated GPCRs. 229th National Meeting of the American Chemical Society, San Diego, California, 13-17 March 2005. Washington DC, United States: American Chemical Society. |
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2009 Book Chapter Tumor-associated antigenic peptides as vaccine candidatesHans, Dhiraj, Young, Paul R. and Fairlie, David P. (2009). Tumor-associated antigenic peptides as vaccine candidates. Tumor-associated antigens. (pp. 303-316) edited by Olivier Gires and Barbara Seliger. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/9783527625970.ch17 |
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2009 Conference Publication Antiviral activity in cell culture of potent inhibitors targeting the West Nile Virus NS2B/NS3 proteaseLiebscher, S., Chappell, K.J., Stoermer, M.J., Fairlie, D.P. and Young, P.R (2009). Antiviral activity in cell culture of potent inhibitors targeting the West Nile Virus NS2B/NS3 protease. 6th General Meeting of the International Proteolysis Society, Gold Coast , QLD, Australia, 26-30 October, 2009. |
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2008 Journal Article West Nile Virus NS2B/NS3 protease as an antiviral targetChappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2008). West Nile Virus NS2B/NS3 protease as an antiviral target. Current Medicinal Chemistry, 15 (27), 2771-2784. doi: 10.2174/092986708786242804 |
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2008 Journal Article Linkage isomerism in the binding of pentapeptide Ac-His(ALA)3His-NH2 to (Ethylenediamine)Palladium(II): Effect of the binding mode on peptide conformationHoang, H.N., Bryant, G.K., Kelso, M.J., Beyer, R.L., Appleton, T.G. and Fairlie, D.P. (2008). Linkage isomerism in the binding of pentapeptide Ac-His(ALA)3His-NH2 to (Ethylenediamine)Palladium(II): Effect of the binding mode on peptide conformation. Inorganic Chemistry, 47 (20), 9439-9449. doi: 10.1021/ic800970p |
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2008 Journal Article Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activityStoermer, Martin J., Chappell, Keith J., Liebscher, Susann, Jensen, Christina M., Gan, Chun H., Gupta, Praveer K., Xu, Wei-Jun, Young, Paul R. and Fairlie, David P. (2008). Potent cationic inhibitors of West Nile Virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity. Journal of Medicinal Chemistry, 51 (18), 5714-5721. doi: 10.1021/jm800503y |
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2008 Journal Article Cyclooligomerization of a helix-bearing template into macrocycles bearing multiple helicesBeyer, Rene´e L., Singh, Yogendra and Fairlie, David P. (2008). Cyclooligomerization of a helix-bearing template into macrocycles bearing multiple helices. Organic Letters, 10 (16), 3481-3484. doi: 10.1021/ol801040c |
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2008 Journal Article Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activityChappell, Keith J., Stoermer, Martin J., Fairlie, David P. and Young, Paul R. (2008). Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity. Journal of General Virology, 89 (4), 1010-1014. doi: 10.1099/vir.0.83447-0 |
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2008 Journal Article Potent antimalarial activity of histone deacetylase inhibitor analoguesAndrews, K. T., Tran, T. N., Lucke, A. J., Kahnberg, P., Le, G. T., Boyle, G. M., Gardiner, D. L., Skinner-Adams, T. S. and Fairlie, D. P. (2008). Potent antimalarial activity of histone deacetylase inhibitor analogues. Antimicrobial agents and chemotherapy, 52 (4), 1454-1461. doi: 10.1128/AAC.00757-07 |
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2008 Journal Article A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteasesMarcon, L., Kozak, D., Battersby, B.J., Chappell, K., Fairlie, D., Young, P.R. and Trau, M. (2008). A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases. Analytical Biochemistry, 2008 (376), 151-153. doi: 10.1016/j.ab.2008.01.034 |
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2008 Journal Article Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic MechanismTyndall, Joel D. A., Pattenden, Leonard K., Reid, Robert C., Hu, Shu-Hong, Alewood, Dianne, Alewood, Paul F., Walsh, Terry, Fairlie, David P. and Martin, Jennifer L. (2008). Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism. Biochemistry, 47 (12), 3736-3744. doi: 10.1021/bi7023157 |
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2008 Journal Article Clean Or dirty - Just how selective do drugs need to be?Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2008). Clean Or dirty - Just how selective do drugs need to be?. Australian Journal of Chemistry, 61 (9), 654-660. doi: 10.1071/CH08186 |
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2008 Conference Publication COMP 264-Unraveling the mechanism of antagonism for human C5a receptor: Comparison of three structurally different antagonistsMadala, P. K., Stoermer, M., Tyndall, J. D. A., Monk, P. N., Higginbottom, A. and Fairlie, D. P. (2008). COMP 264-Unraveling the mechanism of antagonism for human C5a receptor: Comparison of three structurally different antagonists. 236th National Meeting of the American Chemical Society, Philadelphia, USA, 17-21 August, 2008. Washington, D. C., USA: American Chemical Society. |
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2008 Book Chapter Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acidsReid, Robert, C. and Fairlie, David P. (2008). Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acids. High-throughput lead optimisation in drug discovery. (pp. 177-194) edited by Tushar Kshirsagar. Boca Raton, USA: CRC Press. doi: 10.1201/9781420006964.ch7 |
