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2010 Journal Article Inhibitors selective for HDAC6 in enzymes and cellsGupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100 |
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2010 Journal Article Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID componentsWheatley, Nicole C., Andrews, Katherine T., Tran, Truc L., Lucke, Andrew J., Reid, Robert C. and Fairlie, David P. (2010). Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7080-7084. doi: 10.1016/j.bmcl.2010.09.096 |
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2010 Journal Article Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938)Scully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010). Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (Journal of Medicinal Chemistry (2010) 53 (4938). Journal of Medicinal Chemistry, 53 (22), 8208-8208. doi: 10.1021/jm1013314 |
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2010 Journal Article Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cellsSuen, JY, Gardiner, B, Grimmond, S and Fairlie, DP (2010). Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells. PLoS One, 5 (11) e13809, e13809-1-e13809-14. doi: 10.1371/journal.pone.0013809 |
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2010 Journal Article Novel agonists and antagonists for human protease activated receptor 2Barry, Grant D., Suen, Jacky Y., Le, Giang T., Cotterell, Adam, Reid, Robert C. and Fairlie, David P. (2010). Novel agonists and antagonists for human protease activated receptor 2. Journal of Medicinal Chemistry, 53 (20), 7428-7440. doi: 10.1021/jm100984y |
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2010 Conference Publication Modelling of the C5a receptor by iterative mutationHolt, J. R., Monk, P. N., Fairlie, D. P. and Madala, P. Kumar (2010). Modelling of the C5a receptor by iterative mutation. 23rd International National Complement Workshop, New York Ny, Aug 01-05, 2010. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/j.molimm.2010.05.061 |
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2010 Journal Article Selective hexapeptide agonists and antagonists for human complement C3a receptorScully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010). Selective hexapeptide agonists and antagonists for human complement C3a receptor. Journal of Medicinal Chemistry, 53 (13), 4938-4948. doi: 10.1021/jm1003705 |
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2010 Journal Article Update 1 of: beta-strand mimeticsLoughlin, Wendy A., Tyndall, Joel D. A., Glenn, Matthew P., Hill, Timothy A. and Fairlie, David P. (2010). Update 1 of: beta-strand mimetics. Chemical Reviews, 110 (6), PR32-PR69. doi: 10.1021/cr040648k |
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2010 Journal Article Update 1 of: Proteases universally recognize beta strands in their active sitesMadala, Praveen K., Tyndall, Joel D. A., Nall, Tessa and Fairlie, David P. (2010). Update 1 of: Proteases universally recognize beta strands in their active sites. Chemical Reviews, 110 (4), 1-33. doi: 10.1021/cr900368a |
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2010 Journal Article Update 1 of: Beta-strand mimeticsLoughlin, Wendy A., Tyndall, Joel D. A., Glenn, Matthew P., Hill, Timothy A. and Fairlie, David P. (2010). Update 1 of: Beta-strand mimetics. Chemical Reviews, 110 (6), 1-38. doi: 10.1021/cr900395y |
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2010 Journal Article Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potencyHarrison, Rosemary S., Shepherd, Nicholas E., Hoang, Huy N., Ruiz-Goméz, Gloria, Hill, Timothy A., Driver, Russell W., Desai, Vishal S., Young, Paul R., Abbenante, Giovanni and Fairlie, David P. (2010). Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency. Proceedings of the National Academy of Sciences of the United States of America, 107 (26), 11686-11691. doi: 10.1073/pnas.1002498107 |
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2010 Journal Article Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPSHalili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363 |
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2010 Journal Article Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structureRuiz-Gomez, Gloria, Tyndall, Joel D. A., Pfeiffer, Bernhard, Abbenante, Giovanni and Fairlie, David (2010). Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure. Chemical Reviews, 110 (6), 1-41. doi: 10.1021/cr900344w |
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2010 Journal Article Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive ratsIyer, Abishek, Fenning, Andrew, Lim, Junxian, Le, Giang T, Reid, Robert C, Halili, Maria A, Fairlie, David P and Brown, Lindsay (2010). Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. British Journal of Pharmacology, 159 (7), 1408-1417. doi: 10.1111/j.1476-5381.2010.00637.x |
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2010 Journal Article Update 1 of: Over One Hundred Petide-Activated G Protein-Coupled Receptors Recognized Ligands with Turn StructureRuiz-Gomez, Gloria, Tyndall, Joel D. A., Pfeiffer, Bernhard, Abbenante, Giovanni and Fairlie, David P. (2010). Update 1 of: Over One Hundred Petide-Activated G Protein-Coupled Receptors Recognized Ligands with Turn Structure. Chemical Reviews, 110 (4), PR1-PR41. |
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2010 Journal Article Noncovalent tripeptidyl benzyl- And cyclohexyl-amine inhibitors of the cysteine protease caspase-1Loser, Reik, Abbenante, Giovanni, Madala, Praveen K., Halili, Maria, Le, Giang T. and Fairlie, David P. (2010). Noncovalent tripeptidyl benzyl- And cyclohexyl-amine inhibitors of the cysteine protease caspase-1. Journal of Medicinal Chemistry, 53 (6), 2651-2655. doi: 10.1021/jm901790w |
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2010 Journal Article Inflammatory lipid mediators in adipocyte function and obesityIyer, Abishek, Fairlie, David P., Prins, Johannes B., Hammock, Bruce D. and Brown, Lindsay (2010). Inflammatory lipid mediators in adipocyte function and obesity. Nature Reviews Endocrinology, 6 (2), 71-82. doi: 10.1038/nrendo.2009.264 |
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2010 Conference Publication Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substratesLiebscher, Susan, Chappell, K. J., Stoermer, Martin J., Watterson, Daniel, Webb, Richard I., Khromykh, Alexander A., Fairlie, David P. and Young, Paul R. (2010). Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates. PlusStrand 2010: The Ninth International Symposium on Positive-Strand RNA Viruses, Atlanta, GA, U.S.A., 17-21 May 2010. |
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2010 Conference Publication A Novel Protease-Activated Receptor-2 Antagonist Targeting Inflammation and Proliferation in Human Renal Tubular Epithelial CellsVesey David A., Suen, Jacky Yung, Johnson, David W. and Fairlie, David (2010). A Novel Protease-Activated Receptor-2 Antagonist Targeting Inflammation and Proliferation in Human Renal Tubular Epithelial Cells. Kidney Week, American society of Nephrology, Denver Colorado USA, November 16 - 21. Journal of the American Society of Nephrology: |
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2010 Conference Publication Potent inhibitors of West Nile Virus NS2B/NS3 proteaseChappell, K. J., Fairlie, D. P., Gan, C. H., Gupta, P. K., Hu, S., Jensen, C. M., Liebscher, S., Martin, J. L., Robin, G., Stoermer M. J., Xu, W. and Young, P. R. (2010). Potent inhibitors of West Nile Virus NS2B/NS3 protease. 6th General Meeting of the International Proteolysis Society, Gold Coast, QLD, Australia, 26-30 October 2009. Berlin, Germany: Walter De Gruyter. |
