|
2012 Journal Article Towards histone deacetylase inhibitors as new antimalarial drugsAndrews, Katherine T., Tran, Tran N. and Fairlie, David P. (2012). Towards histone deacetylase inhibitors as new antimalarial drugs. Current Pharmaceutical Design, 18 (24), 3467-3479. doi: 10.2174/138161212801327257 |
|
2012 Journal Article A comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly Gi coupled GPCR (C5aR) signallingHalai, Reena, Croker, Daniel E., Suen, Jacky Y., Fairlie, David P. and Cooper, Matthew A. (2012). A comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly Gi coupled GPCR (C5aR) signalling. Biosensors, 2 (3), 273-290. doi: 10.3390/bios2030273 |
|
2012 Journal Article Antimalarial activity of the anticancer histone deacetylase inhibitor SB939Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P. and Andrews, Katherine T. (2012). Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. Antimicrobial Agents and Chemotherapy, 56 (7), 3849-3856. doi: 10.1128/AAC.00030-12 |
|
2012 Journal Article Towards isozyme-selective HDA inhibitors for interrogating diseaseGupta, Praveer, Reid, Robert C., Iyer, Abishek, Sweet, Matthew J. and Fairlie, David (2012). Towards isozyme-selective HDA inhibitors for interrogating disease. Current Topics in Medicinal Chemistry, 12 (14), 1479-1499. doi: 10.2174/156802612802652420 |
|
2012 Journal Article Chemical biology down underFairlie, David (2012). Chemical biology down under. Current Topics in Medicinal Chemistry, 12 (14), 1469-1470. doi: 10.2174/156802612802652475 |
|
2012 Journal Article An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in ratsLohman, Rink-Jan, Cotterell, Adam J., Barry, Grant D., Liu, Ligong, Suen, Jacky Y., Vesey, David A. and Fairlie, David P. (2012). An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. The FASEB Journal, 26 (7), 2877-2887. doi: 10.1096/fj.11-201004 |
|
2012 Journal Article Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseasesCantley, Melissa D., Bartold, Peter M., Fairlie, David P., Rainsford, K. D. and Haynes, David R. (2012). Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases. Journal of Pharmacy and Pharmacology, 64 (6), 763-774. doi: 10.1111/j.2042-7158.2011.01421.x |
|
2012 Journal Article Folding pentapeptides into left and right handed alpha helicesHoang, Huy N., Abbenante, Giovanni, Hill, Timothy A., Ruiz-Gomez, Gloria and Fairlie, David P. (2012). Folding pentapeptides into left and right handed alpha helices. Tetrahedron, 68 (23), 4513-4516. doi: 10.1016/j.tet.2011.10.108 |
|
2012 Journal Article Matching cavities in G protein-coupled receptors to infer ligand-binding sitesMadala, Praveen K., Fairlie, David P. and Bodén, Mikael (2012). Matching cavities in G protein-coupled receptors to infer ligand-binding sites. Journal of Chemical Information and Modeling, 52 (5), 1401-1410. doi: 10.1021/ci2005498 |
|
2012 Conference Publication Concise synthesis of the thiazole-thiazoline fragment of largazoleDiness, Frederik, Nielsen, Daniel S. and Fairlie, David P. (2012). Concise synthesis of the thiazole-thiazoline fragment of largazole. 243rd National Spring Meeting of the American-Chemical-Society, San Diego Ca, Mar 25-29, 2012. WASHINGTON: AMER CHEMICAL SOC. |
|
2012 Conference Publication Fluorobenzene derivatives as multifunctional toolsDiness, Frederik, Begtrup, Mikael Begtrup and Fairlie, David P. (2012). Fluorobenzene derivatives as multifunctional tools. 243rd National Spring Meeting of the American-Chemical-Society, San Diego Ca, Mar 25-29, 2012. WASHINGTON: AMER CHEMICAL SOC. |
|
2012 Journal Article Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)Suen, J. Y., Barry, G. D., Lohman, R. J., Halili, M. A., Cotterell, A. J., Le, G. T. and Fairlie, D. P. (2012). Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). British Journal of Pharmacology, 165 (5), 1413-1423. doi: 10.1111/j.1476-5381.2011.01610.x |
|
2012 Journal Article C5a receptor (CD88) and TLR2 inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic modelThundyil, John, Pavlovski, Dale, Hsieh, Yu-Hsuan, Gelderblom, Mathias, Magnus, Tim, Fairlie, David P. and Arumugam, Thiruma V. (2012). C5a receptor (CD88) and TLR2 inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model. NeuroMolecular Medicine, 14 (1), 30-39. doi: 10.1007/s12017-012-8167-0 |
|
2012 Journal Article Antagonism of protease-activated receptor 2 protects against experimental colitis.Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky, Liu, Ligong, Do, Anh T., Vesey, David A. and Fairlie, David P. (2012). Antagonism of protease-activated receptor 2 protects against experimental colitis.. Journal of Pharmacology and Experimental Therapeutics, 340 (2), 256-265. doi: 10.1124/jpet.111.187062 |
|
2012 Journal Article Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitorsAndrews, Katherine T., Gupta, Archna P., Tran, Thanh N., Fairlie, David P., Gobert, Geoffrey N. and Bozdech, Zbynek (2012). Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors. Plos One, 7 (2) e31847, e31847-1-e31847-9. doi: 10.1371/journal.pone.0031847 |
|
2012 Journal Article Lysine acetylation in obesity, diabetes and metabolic diseaseIyer, Abishek, Fairlie, David P. and Brown, Lindsay (2012). Lysine acetylation in obesity, diabetes and metabolic disease. Immunology and Cell Biology, 90 (1), 39-46. doi: 10.1038/icb.2011.99 |
|
2012 Conference Publication Ligand-induced dimerisation of the complement C5aR and C5L2 receptors by C5a but not C5a-des ArgCroker, Daniel E., Halai, Reena, Fairlie, David P. and Cooper, Matthew A. (2012). Ligand-induced dimerisation of the complement C5aR and C5L2 receptors by C5a but not C5a-des Arg. XXIV International Complement Workshop (ICW), Crete, Greece, 10-15 October 2012. Jena, Germany: Urban und Fischer Verlag. doi: 10.1016/j.imbio.2012.08.152 |
|
2012 Conference Publication Shedding light on MHC class I antigen loading: a UV-labile peptide ligand approachTheodossis, A., Ruiz-Gomez, G., Gibb, A., Welland, A., Jones, P., Fairlie, D. and Rossjohn, J. (2012). Shedding light on MHC class I antigen loading: a UV-labile peptide ligand approach. 32nd European Peptide Symposium "Peptides 2012", Athens, Greece, 02-07 September 2012. West Sussex, United Kingdom: John Wiley and Sons. doi: 10.1002/psc.2447 |
|
2012 Journal Article HDACs and their inhibitors in immunology: teaching anticancer drugs new tricksFairlie, David P. and Sweet, Matthew J. (2012). HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks. Immunology and Cell Biology, 90 (1), 3-5. doi: 10.1038/icb.2011.105 |
|
2012 Conference Publication Shedding light on MHC class I antigen loading: A UV-labile peptide ligand approachTheodossis, Alex, Ruiz-Gomez, Gloria, Gibb, Andrew, Welland, Andrew, Jones, Paul, Fairlie, David and Rossjohn, Jamie (2012). Shedding light on MHC class I antigen loading: A UV-labile peptide ligand approach. 7th International EMBO Workshop on Antigen Presentation and Processing, Amsterdam, Netherlands, 24-27 April 2012. Oxford, United Kingdom: Pergamon. doi: 10.1016/j.molimm.2012.02.094 |
