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2007

Conference Publication

Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets

Andrews, Kathy T., Tran, Thanh N., Lucke, Andrew, Kahnberg, Pia, Lee, G. T., Skinner-Adams, Tina, Gardiner, Donald L. and Fairlie, David P. (2007). Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, Philadelphia, PA United States, 04-08 November 2007. Deerfield, IL United States: American Society of Tropical Medicine and Hygiene.

Plasmodium falciparum histone deacetylases: Enzymes involved in gene regulation as new antimalarial drug targets

2007

Journal Article

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

Arumugam, T. V, Tang, S. C, Lathia, J. D, Cheng, A, Mughal, M. R, Chigurupati, S, Magnus, T, Chan, S. L, Jo, D. G, Ouyang, X, Fairlie, D. P, Granger, D. N, Vortmeyer, A, Basta, M and Mattson, M. P (2007). Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death. Proceedings of The National Academy of Sciences of The United States of America, 104 (35), 14104-14109. doi: 10.1073/pnas.0700506104

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

2006

Conference Publication

Discussion

Rice, Charles, Heinz, Franz X., Kuhn, Richard, Harris, Eva, Fairlie, David, Young, Paul, Flamand, Marie, Zinkernagel, Rolf, Halstead, Scott, Evans, Thomas G., Jans, David A. and Screaton, Gavin (2006). Discussion.

Discussion

2006

Conference Publication

Discussion

Fairlie, David, Gubler, Duane J., Holmes, Edward, Halstead, Scott, Hombach, Joachim, Harris, Eva, Hibberd, Martin, Vasudevan, Subhash, Evans, Thomas G., Keller, Thomas, Gu, Feng, Stephenson, John, Canard, Bruno, Malasit, Prida and Zinkernagel, Rolf (2006). Discussion.

Discussion

2006

Conference Publication

Discussion

Rice, Charles, Hibberd, Martin, Gu, Feng, Harris, Eva, Jans, David A., Farrar, Jeremy, Vasudevan, Subhash, Evans, Thomas G., Holmes, Edward, Fairlie, David and Keller, Thomas (2006). Discussion. Novartis Foundation.

Discussion

2006

Conference Publication

Discussion

Rice, Charles, Padmanabhan, R. Pad, Canard, Bruno, Vasudevan, Subhash, Satchidanandam, Vijaya, Fairlie, David, Gamarnik, Andrea and Kuhn, Richard (2006). Discussion.

Discussion

2006

Conference Publication

Discussion

Young, Paul, Keller, Thomas, Padmanabhan, R. Pad, Fairlie, David, Hibberd, Martin, Rice, Charles, Canard, Bruno, Vasudevan, Subhash, Screaton, Gavin, Harris, Eva, Gu, Feng, Halstead, Scott, Farrar, Jeremy, Holmes, Edward, Malasit, Prida and Evans, Thomas G. (2006). Discussion. Novartis Foundation.

Discussion

2006

Conference Publication

General discussion I

Rice, Charles, Heinz, Franz X., Young, Paul, Kuhn, Richard, Neyts, Johan, Keller, Thomas, Fairlie, David, Guber, Duane J. and Screaton, Gavin (2006). General discussion I.

General discussion I

2006

Conference Publication

Discussion

Harris, Eva, Screaton, Gavin, Farrar, Jeremy, Hombach, Joachim, Halstead, Scott, Rice, Charles, Holmes, Edward, Satchidanandam, Vijaya, Young, Paul, Zinkernagel, Rolf, Flamand, Marie, Malasit, Prida and Fairlie, David (2006). Discussion. Novartis Foundation.

Discussion

2006

Conference Publication

MEDI 180-Effects of cyclization constraints on helix/turn peptide structures

Beyer, Renee L., Hoang, Huy N., Le, Giang T. and Fairlie, David P. (2006). MEDI 180-Effects of cyclization constraints on helix/turn peptide structures. WASHINGTON: AMER CHEMICAL SOC.

MEDI 180-Effects of cyclization constraints on helix/turn peptide structures

2006

Conference Publication

MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators

Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators. WASHINGTON: AMER CHEMICAL SOC.

MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators

2006

Journal Article

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

Gregory, Laura S., Kelly, Wendy L., Reid, Robert C., Fairlie, David P. and Forwood, Mark R. (2006). Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats. Bone, 39 (1), 134-142. doi: 10.1016/j.bone.2005.12.017

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

2006

Journal Article

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006). Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 (11), 7000-7007. doi: 10.4049/jimmunol.176.11.7000

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

2006

Conference Publication

Defining the ligand binding site on the human C5a receptor

Monk, Peter N., Higginbottom, Adrian, Madala, Praveen K., Tyndall, Joel D. A., Stoermer, Martin and Fairlie, David P. (2006). Defining the ligand binding site on the human C5a receptor. 231st National Meeting of the American-Chemical-Society, Atlanta Ga, Mar 26-30, 2006. WASHINGTON: AMER CHEMICAL SOC.

Defining the ligand binding site on the human C5a receptor

2006

Journal Article

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006). Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 (2), 639-648. doi: 10.1128/AAC.50.2.639-648.2006

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

2006

Conference Publication

Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification

Chappell, K. J., Stoermer, M J, Fairlie, D and Young, P R (2006). Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Qld, 2-6 July, 2006.

Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification

2006

Journal Article

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus

Shepherd, Nicholas E., Hoang, Huy N., Desai, Vishal S., Letouze, Eric, Young, Paul R. and Fairlie, David P. (2006). Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus. Journal of The American Chemical Society, 128 (40), 13284-13289. doi: 10.1021/ja064058a

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus

2006

Conference Publication

Alpha helix induction in HIV REV34-50 by N-terminal nucleators

Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). Alpha helix induction in HIV REV34-50 by N-terminal nucleators. 232nd ACS National Meeting, San Francisco, CA, U.S.A., 10-14 September, 2006. American Chemical Society. doi: 10.1021/cen-v084n034.p055

Alpha helix induction in HIV REV34-50 by N-terminal nucleators

2006

Journal Article

New insights into growth hormone action

Waters, M. J., Hoang, H. N., Fairlie, D. P., Pelekanos, R. A. and Brown, R. J. (2006). New insights into growth hormone action. Journal of Molecular Endocrinology, 36 (1), 1-7. doi: 10.1677/jmr.1.01933

New insights into growth hormone action

2006

Journal Article

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2006). Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies. Journal of Biological Chemistry, 281 (50), 38448-38458. doi: 10.1074/jbc.M607641200

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies