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2006

Conference Publication

General discussion I

Rice, Charles, Heinz, Franz X., Young, Paul, Kuhn, Richard, Neyts, Johan, Keller, Thomas, Fairlie, David, Guber, Duane J. and Screaton, Gavin (2006). General discussion I.

General discussion I

2006

Conference Publication

Discussion

Harris, Eva, Screaton, Gavin, Farrar, Jeremy, Hombach, Joachim, Halstead, Scott, Rice, Charles, Holmes, Edward, Satchidanandam, Vijaya, Young, Paul, Zinkernagel, Rolf, Flamand, Marie, Malasit, Prida and Fairlie, David (2006). Discussion. Novartis Foundation.

Discussion

2006

Conference Publication

Discussion

Rice, Charles, Heinz, Franz X., Kuhn, Richard, Harris, Eva, Fairlie, David, Young, Paul, Flamand, Marie, Zinkernagel, Rolf, Halstead, Scott, Evans, Thomas G., Jans, David A. and Screaton, Gavin (2006). Discussion.

Discussion

2006

Conference Publication

Discussion

Fairlie, David, Gubler, Duane J., Holmes, Edward, Halstead, Scott, Hombach, Joachim, Harris, Eva, Hibberd, Martin, Vasudevan, Subhash, Evans, Thomas G., Keller, Thomas, Gu, Feng, Stephenson, John, Canard, Bruno, Malasit, Prida and Zinkernagel, Rolf (2006). Discussion.

Discussion

2006

Conference Publication

MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators

Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators. WASHINGTON: AMER CHEMICAL SOC.

MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators

2006

Conference Publication

MEDI 180-Effects of cyclization constraints on helix/turn peptide structures

Beyer, Renee L., Hoang, Huy N., Le, Giang T. and Fairlie, David P. (2006). MEDI 180-Effects of cyclization constraints on helix/turn peptide structures. WASHINGTON: AMER CHEMICAL SOC.

MEDI 180-Effects of cyclization constraints on helix/turn peptide structures

2006

Journal Article

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

Gregory, Laura S., Kelly, Wendy L., Reid, Robert C., Fairlie, David P. and Forwood, Mark R. (2006). Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats. Bone, 39 (1), 134-142. doi: 10.1016/j.bone.2005.12.017

Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats

2006

Journal Article

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006). Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 (11), 7000-7007. doi: 10.4049/jimmunol.176.11.7000

Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats

2006

Conference Publication

Defining the ligand binding site on the human C5a receptor

Monk, Peter N., Higginbottom, Adrian, Madala, Praveen K., Tyndall, Joel D. A., Stoermer, Martin and Fairlie, David P. (2006). Defining the ligand binding site on the human C5a receptor. 231st National Meeting of the American-Chemical-Society, Atlanta Ga, Mar 26-30, 2006. WASHINGTON: AMER CHEMICAL SOC.

Defining the ligand binding site on the human C5a receptor

2006

Journal Article

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006). Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 (2), 639-648. doi: 10.1128/AAC.50.2.639-648.2006

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria

2006

Journal Article

Current Status of Short Synthetic Peptides as Vaccines

Hans, D., Young, P. R. and Fairlie, D. (2006). Current Status of Short Synthetic Peptides as Vaccines. Medicinal Chemistry, 2 (6), 627-646. doi: 10.2174/1573406410602060627

Current Status of Short Synthetic Peptides as Vaccines

2006

Conference Publication

New Treatment Strategies for Dengue and other Flaviviral Diseases

Fairlie, D. (2006). New Treatment Strategies for Dengue and other Flaviviral Diseases. Norvatis foundations Symposium 277 on New Treatment Strategies for Dengue and other Flaviviral Diseases, Singapore, 26-27 September, 2005. Chichester, UK: John Wiley and Sons.

New Treatment Strategies for Dengue and other Flaviviral Diseases

2006

Journal Article

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2006). Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies. Journal of Biological Chemistry, 281 (50), 38448-38458. doi: 10.1074/jbc.M607641200

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

2006

Journal Article

Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops

Singh, Y, Hoang, HN, Flanagan, B and Fairlie, DP (2006). Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops. Organic Letters, 8 (6), 1053-1056. doi: 10.1021/ol052842e

Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops

2006

Journal Article

Organic Azide Inhibitors of Cysteine Proteases

Le, G. T., Abbenante, G., Madala, P. K., Hoang, H. N. and Fairlie, D. P. (2006). Organic Azide Inhibitors of Cysteine Proteases. Journal of the American Chemical Society, 128 (38), 12396-12397. doi: 10.1021/ja0637649

Organic Azide Inhibitors of Cysteine Proteases

2006

Conference Publication

Final discussion

Ng Mah Lee, Mary, Rice, Charles, Fairlie, David, Zinkernagel, Rolf, Young, Paul, Neyts, Johan, Hibberd, Martin, Holmes, Edward, Heinz, Franz X. and Stephenson, John (2006). Final discussion. Novartis Foundation Symposium 277: New treatment strategies for Dengue and other flaviviral diseases, *, 2006. John Wiley & Sons.

Final discussion

2006

Conference Publication

Multiple targets for antiviral inhibitors

Young, P. R., Chappell, K. J., Stoermer, M. J., Fairlie, D., Kampmann, T. and Kobe, B. (2006). Multiple targets for antiviral inhibitors. 7th Asia Pacific Congress of Virology, New Delhi, 13-15 Nov, 2006.

Multiple targets for antiviral inhibitors

2006

Conference Publication

Defining the ligand binding site on the human C5a receptor

Monk, Peter N., Higginbottom, Adrian, Madala, Praveen K., Tyndall, Joel D. A., Stoermer, Martin and Fairlie, David P. (2006). Defining the ligand binding site on the human C5a receptor. The 231st ACS National Meeting, Atlanta, GA, U.S.A., 26-30 March 2006. Washington, D.C.: American Chemical Society.

Defining the ligand binding site on the human C5a receptor

2006

Journal Article

Design, Synthesis, Potency and Cytoselectivity of Anticancer Agents Derived by Parallel Synthesis from alpha-Aminosuberic Acid

Kahnberg, P. C., Lucke, A., Glenn, M. P., Boyle, G. M., Tyndall, J. D., Parsons, P. G. and Fairlie, D. P. (2006). Design, Synthesis, Potency and Cytoselectivity of Anticancer Agents Derived by Parallel Synthesis from alpha-Aminosuberic Acid. Journal of Medicinal Chemistry, 49 (26), 7611-7622. doi: 10.1021/jm050214x

Design, Synthesis, Potency and Cytoselectivity of Anticancer Agents Derived by Parallel Synthesis from alpha-Aminosuberic Acid

2006

Conference Publication

Developing antiviral targets for RSV via mutational analysis of HRB and HRC domains using a novel fusion assay system

Desai, A., Khlentzos, A., Shepherd, N., Hoang, H. N., Letouze, E., Fairlie, D. and Young, P. R. (2006). Developing antiviral targets for RSV via mutational analysis of HRB and HRC domains using a novel fusion assay system. 13th International Conference of Negative Strand Viruses, Salamanca, 17-22 June, 2006.

Developing antiviral targets for RSV via mutational analysis of HRB and HRC domains using a novel fusion assay system