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2005

Conference Publication

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis. International Congress of Virology, San Francisco, 23-27 July, 2005.

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

2005

Conference Publication

Alpha-helix induction in short peptides using metal clips

Ma, M. T., Hoang, H. N., Beyer, R. L., Bryant, G. K., Appleton, T. G. and Fairlie, D. (2005). Alpha-helix induction in short peptides using metal clips. International Chemical Congress of Pacific Basin Societies (Pacifichem2005), Honolulu, Hawaii, 15 - 20 December 2005. WASHINGTON: AMER CHEMICAL SOC.

Alpha-helix induction in short peptides using metal clips

2005

Conference Publication

Modular alpha-helices: conformationally stable cyclic pentapeptides as alpha-turn mimetics

Shepherd, Nicholas E., Hoang, Huy N., Abbenante, Giovanni and Fairlie, David P. (2005). Modular alpha-helices: conformationally stable cyclic pentapeptides as alpha-turn mimetics. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague, Czech Republic, 5-10 September 2004. Geneva, Switzerland: Kenes INT.

Modular alpha-helices: conformationally stable cyclic pentapeptides as alpha-turn mimetics

2005

Journal Article

Over 100 peptide-activated GPCRS recognize turn motifs in ligands

Fairlie, D. P., Tyndall, J. D. A., Abbenante, G. and Pfeiffer, B. (2005). Over 100 peptide-activated GPCRS recognize turn motifs in ligands. Abstracts of Papers of The American Chemical Society, 229, U106-U106.

Over 100 peptide-activated GPCRS recognize turn motifs in ligands

2005

Conference Publication

Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis. 3rd Australian Virology Group Meeting, Phillip Island, Vic., 9-12 Dec, 2005.

Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis

2005

Journal Article

Protease inhibitors in the clinic

Abbenante, Giovanni and Fairlie , David P. (2005). Protease inhibitors in the clinic. Medicinal Chemistry, 1 (1), 71-104. doi: 10.2174/1573406053402569

Protease inhibitors in the clinic

2005

Journal Article

Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure

Tyndall, J. D. A., Pfeiffer, B., Abbenante, G. and Fairlie, D. P. (2005). Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure. Chemical Reviews, 105 (3), 793-826. doi: 10.1021/cr040689g

Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure

2005

Journal Article

Tumour necrosis factor alpha converting enzyme

Fairlie, D (2005). Tumour necrosis factor alpha converting enzyme. Current Medicinal Chemistry, 12 (25), 2923-2924. doi: 10.2174/092986705774462897

Tumour necrosis factor alpha converting enzyme

2005

Conference Publication

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis. 30th Lorne Conference on Protein Structure & Function, Lorne, 6-10 Feb, 2005.

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

2005

Journal Article

Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles

Singh, Y, Stoermer, MJ, Lucke, AJ, Guthrie, T and Fairlie, DP (2005). Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles. Journal of The American Chemical Society, 127 (18), 6563-6572. doi: 10.1021/ja0455300

Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles

2004

Journal Article

Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent

van den Brenk, Anna L., Tyndall, Joel D. A., Cusack, Rodney M., Jones, Alun, Fairlie, David P., Gahan, Lawrence R. and Hanson, Graeme R. (2004). Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent. Journal of Inorganic Biochemistry, 98 (11), 1857-1866. doi: 10.1016/j.jinorgbio.2004.08.005

Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent

2004

Journal Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/S0168-8278(04)00066-2

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

2004

Journal Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and M. Colombo (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/j.jhep.2004.02.017

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

2004

Journal Article

Alpha-turn mimetics: short peptide alpha-Helices composed of cyclic metallopentapeptide modules

Kelso, Michael J., Beyer, Renée L., Hoang, Huy N., Lakdawala, Ami S., Snyder, James P., Oliver, Warren V., Robertson, Tom A., Appleton, Trevor G. and Fairlie, David P. (2004). Alpha-turn mimetics: short peptide alpha-Helices composed of cyclic metallopentapeptide modules. Journal of The American Chemical Society, 126 (15), 4828-4842. doi: 10.1021/ja037980i

Alpha-turn mimetics: short peptide alpha-Helices composed of cyclic metallopentapeptide modules

2004

Other Outputs

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P., Fairlie, David P. and Schafer, Karl (2004). Compounds and inhibitors of phospholipases. US2004033995.

Compounds and inhibitors of phospholipases

2004

Journal Article

Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury

Proctor, Lavinia M., Arumugam, Thiruma V., Shiels, Ian, Reid, Robert C., Fairlie, David P. and Taylor, Stephen M . (2004). Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury. British Journal of Pharmacology, 142 (4), 756-764. doi: 10.1038/sj.bjp.0705819

Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury

2004

Conference Publication

Towards Modular Alpha-Helices: Comformationally Stable Cyclic Pentapeptides as Alpha-Turn Mimetics

Shepherd, N. E., Hoang, H., Abbenante, G. and Fairlie, D. P. (2004). Towards Modular Alpha-Helices: Comformationally Stable Cyclic Pentapeptides as Alpha-Turn Mimetics. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague Czech Republic, Sep 05-10, 2004. GENEVA 1: JOHN WILEY & SONS LTD.

Towards Modular Alpha-Helices: Comformationally Stable Cyclic Pentapeptides as Alpha-Turn Mimetics

2004

Journal Article

Antiproliferative and phenotype-transforming antitumor agents derived from cysteine

Glenn, MP, Kahnberg, P, Boyle, GM, Hansford, KA, Hans, D, Martyn, AC, Parsons, PG and Fairlie, DP (2004). Antiproliferative and phenotype-transforming antitumor agents derived from cysteine. Journal of Medicinal Chemistry, 47 (12), 2984-2994. doi: 10.1021/jm030222i

Antiproliferative and phenotype-transforming antitumor agents derived from cysteine

2004

Journal Article

Beta-strand mimetics

Loughlin, WA, Tyndall, JDA, Glenn, MP and Fairlie, DP (2004). Beta-strand mimetics. Chemical Reviews, 104 (12), 6085-6117. doi: 10.1021/cr040648k

Beta-strand mimetics

2004

Conference Publication

Small molecules that mimic components of bioactive protein surfaces

Fairlie, DP (2004). Small molecules that mimic components of bioactive protein surfaces. Australia: CSIRO Publishing. doi: 10.1071/CH04074

Small molecules that mimic components of bioactive protein surfaces