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2004 Journal Article Beta-strand mimeticsLoughlin, WA, Tyndall, JDA, Glenn, MP and Fairlie, DP (2004). Beta-strand mimetics. Chemical Reviews, 104 (12), 6085-6117. doi: 10.1021/cr040648k |
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2004 Conference Publication Small molecules that mimic components of bioactive protein surfacesFairlie, DP (2004). Small molecules that mimic components of bioactive protein surfaces. Australia: CSIRO Publishing. doi: 10.1071/CH04074 |
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2004 Conference Publication Cardiovascular structural and functional adaptations to group IIAsPLA2 inhibitionLevick, S., Taylor, S. M., Fairlie, D. and Brown, L. C. (2004). Cardiovascular structural and functional adaptations to group IIAsPLA2 inhibition. 2004 ISHR World Congress, Brisbane, Australia, 7-11/8/04. London: Academic Press. |
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2004 Journal Article Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activityMarch, Darren R., Proctor, Lavinia M., Stoermer, Martin J., Sbaglia, Robert, Abbenante, Giovanni, Reid, Robert C., Woodruff, Trent M., Wadi, Khemar, Paczkowski, Natalii, Tyndall, Joel D. A., Taylor, Stephen M. and Fairlie, David P. (2004). Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity. Molecular Pharmacology, 65 (4), 868-879. doi: 10.1124/mol.65.4.868 |
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2004 Journal Article Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 proteaseNall, T. A., Chappell, K. J., Stoermer, M. J., Fang, N. X., Tyndall, J. D. A., Young, P. R. and Fairlie, D. P. (2004). Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease. Journal of Biological Chemistry, 279 (47), 48535-48542. doi: 10.1074/jbc.M406810200 |
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2004 Journal Article Metal Clips Induce Folding of a Short Unstructured Peptide into an a-Helix via Turn Conformations in Water. Kinetic versus Thermodynamic ProductsBeyer, Renee L., Hoang, Huy N., Appleton, Trevor G. and Fairlie, David P. (2004). Metal Clips Induce Folding of a Short Unstructured Peptide into an a-Helix via Turn Conformations in Water. Kinetic versus Thermodynamic Products. Journal of The American Chemical Society, 126 (46), 15096-15105. doi: 10.1021/ja0453782 |
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2004 Journal Article Consecutive cyclic pentapeptide modules form short alpha-helices that are very stable to water and denaturantsShepherd, N. E., Abbenante, G. and Fairlie, D. P. (2004). Consecutive cyclic pentapeptide modules form short alpha-helices that are very stable to water and denaturants. Angewandte Chemie-international Edition, 43 (20), 2687-2690. doi: 10.1002/anie.200352659 |
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2003 Journal Article A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel diseaseWoodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003). A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 (10), 5514-5520. doi: 10.4049/jimmunol.171.10.5514 |
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2003 Journal Article Studies of the interaction of Potassium(I), Calcium(II), Magnesium(II), and Copper(II) with Cyclosporin ACusack, Rodney M., Grondahl, Lisbeth, Fairlie, David P., Hanson, Graeme R. and Gahan, Lawrence R. (2003). Studies of the interaction of Potassium(I), Calcium(II), Magnesium(II), and Copper(II) with Cyclosporin A. Journal of Inorganic Biochemistry, 97 (2), 191-198. doi: 10.1016/S0162-0134(03)00288-5 |
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2003 Journal Article Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonistArumugam, Thiruma V., Arnold, Naomi, Proctor, Lavinia M., Newman, Michelle, Reid, Robert C., Hansford, Karl A., Fairlie, David P., Shiels, Ian A. and Taylor, Stephen M. (2003). Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British Journal of Pharmacology, 140 (1), 71-80. doi: 10.1038/sj.bjp.0705402 |
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2003 Journal Article A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drugReid, Robert C., Abbenante, Giovanni, Taylor, Stephen M. and Fairlie, David P. (2003). A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug. Journal of Organic Chemistry, 68 (11), 4464-4471. doi: 10.1021/jo034228r |
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2003 Other Outputs New cyclic peptide or peptidomimetic compounds, are G-protein coupled receptor antagonists useful for treating inflammatory disorders such as rheumatoid arthritis, reperfusion injury or dermal inflammationTaylor, Steve, Shiels, Ian Alexander and Fairlie, David (2003). New cyclic peptide or peptidomimetic compounds, are G-protein coupled receptor antagonists useful for treating inflammatory disorders such as rheumatoid arthritis, reperfusion injury or dermal inflammation. WO/2003/033528. |
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2003 Conference Publication Template-assembled peptide loops, helices, sheets and nanofibresFairlie, DP, Singh, Y, Sharpe, P and Stoermer, M (2003). Template-assembled peptide loops, helices, sheets and nanofibres. 225th National Meeting of the American-Chemical-Society, New Orleans Louisiana, Mar 23-27, 2003. WASHINGTON: AMER CHEMICAL SOC. |
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2003 Journal Article A cyclic metallopeptide induces alpha helicity in short peptide fragments of thermolysinKelso, Michael J., Hoang, Huy N., Oliver, Warren, Sokolenko, Nikolai, March, Darren R., Appleton, Trevor G. and Fairlie, David P. (2003). A cyclic metallopeptide induces alpha helicity in short peptide fragments of thermolysin. Angewandte Chemie International Edition, 42 (4), 421-424. doi: 10.1002/anie.200390128 |
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2003 Conference Publication Short peptide alpha helices induced by multiple metal clipsHoang, Huy N., Bryant, Gavin K., Kelso, Micheal J., Beyer, Renee L., Appleton, Trevor G. and Fairlie, David P. (2003). Short peptide alpha helices induced by multiple metal clips. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19-23 July, 2003. New York, USA: Elsevier. doi: 10.1016/S0162-0134(03)80638-4 |
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2003 Conference Publication Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin AGahan, Lawrence R., Cusack, Rodney M., Grondahl, Lisbeth H., Fairlie, David P. and Hanson, Graeme R. (2003). Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin A. 11th International Conference on Biological Inorganic Chemistry, New York, USA, 19-23July, 2003. New York, USA: Elseiver. doi: 10.1016/S0162-0134(03)80624-4 |
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2003 Journal Article Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashionWilliamson, A. L., Brindley, P. J., Abbenante, G., Datu, B. J. D., Prociv, P., Berry, C., Girdwood, K., Pritchard, D. I., Fairlie, D. P., Hotez, P. J., Zhan, B. and Loukas, A. (2003). Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. Journal of Infectious Diseases, 187 (3), 484-494. doi: 10.1086/367708 |
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2003 Journal Article D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activityHansford, Karl A., Reid, Robert C., Clark, Chris I., Tyndall, Joel D. A., Whitehouse, Michael W., Guthrie, Tom, McGeary, Ross P., Schafer, Karl, Martin, Jennifer L. and Fairlie, David P. (2003). D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activity. Chembiochem, 4 (2-3), 181-185. doi: 10.1002/cbic.200390029 |
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2003 Conference Publication Template-assembled peptide loops, helices, sheets, and nanofibersFairlie, David P ., Singh, Yogendra, Sharpe, Philip and Stoermer, Martin (2003). Template-assembled peptide loops, helices, sheets, and nanofibers. 225th ACS National Meeting, New Orleans, LA, United States, 23-27 March 2003. |
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2003 Journal Article A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in ratsArumugam, T. V., Shiels, I. A., Strachan, A. J., Abbenante, G., Fairlie, D. P. and Taylor, S. M. (2003). A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. Kidney International, 63 (1), 134-142. doi: 10.1046/j.1523-1755.2003.00737.x |
