2004 Journal Article Beta-strand mimeticsLoughlin, WA, Tyndall, JDA, Glenn, MP and Fairlie, DP (2004). Beta-strand mimetics. Chemical Reviews, 104 (12), 6085-6117. doi: 10.1021/cr040648k |
2004 Conference Publication Small molecules that mimic components of bioactive protein surfacesFairlie, DP (2004). Small molecules that mimic components of bioactive protein surfaces. Australia: CSIRO Publishing. doi: 10.1071/CH04074 |
2004 Conference Publication Towards Modular Alpha-Helices: Comformationally Stable Cyclic Pentapeptides as Alpha-Turn MimeticsShepherd, N. E., Hoang, H., Abbenante, G. and Fairlie, D. P. (2004). Towards Modular Alpha-Helices: Comformationally Stable Cyclic Pentapeptides as Alpha-Turn Mimetics. 3rd International Peptide Symposium/28th European Peptide Symposium, Prague Czech Republic, Sep 05-10, 2004. GENEVA 1: JOHN WILEY & SONS LTD. |
2004 Conference Publication Cardiovascular structural and functional adaptations to group IIAsPLA2 inhibitionLevick, S., Taylor, S. M., Fairlie, D. and Brown, L. C. (2004). Cardiovascular structural and functional adaptations to group IIAsPLA2 inhibition. 2004 ISHR World Congress, Brisbane, Australia, 7-11/8/04. London: Academic Press. |
2003 Journal Article A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel diseaseWoodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003). A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 (10), 5514-5520. doi: 10.4049/jimmunol.171.10.5514 |
2003 Journal Article Studies of the interaction of Potassium(I), Calcium(II), Magnesium(II), and Copper(II) with Cyclosporin ACusack, Rodney M., Grondahl, Lisbeth, Fairlie, David P., Hanson, Graeme R. and Gahan, Lawrence R. (2003). Studies of the interaction of Potassium(I), Calcium(II), Magnesium(II), and Copper(II) with Cyclosporin A. Journal of Inorganic Biochemistry, 97 (2), 191-198. doi: 10.1016/S0162-0134(03)00288-5 |
2003 Journal Article Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonistArumugam, Thiruma V., Arnold, Naomi, Proctor, Lavinia M., Newman, Michelle, Reid, Robert C., Hansford, Karl A., Fairlie, David P., Shiels, Ian A. and Taylor, Stephen M. (2003). Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British Journal of Pharmacology, 140 (1), 71-80. doi: 10.1038/sj.bjp.0705402 |
2003 Journal Article A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drugReid, Robert C., Abbenante, Giovanni, Taylor, Stephen M. and Fairlie, David P. (2003). A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug. Journal of Organic Chemistry, 68 (11), 4464-4471. doi: 10.1021/jo034228r |
2003 Other Outputs New cyclic peptide or peptidomimetic compounds, are G-protein coupled receptor antagonists useful for treating inflammatory disorders such as rheumatoid arthritis, reperfusion injury or dermal inflammationTaylor, Steve, Shiels, Ian Alexander and Fairlie, David (2003). New cyclic peptide or peptidomimetic compounds, are G-protein coupled receptor antagonists useful for treating inflammatory disorders such as rheumatoid arthritis, reperfusion injury or dermal inflammation. WO/2003/033528. |
2003 Conference Publication Template-assembled peptide loops, helices, sheets and nanofibresFairlie, DP, Singh, Y, Sharpe, P and Stoermer, M (2003). Template-assembled peptide loops, helices, sheets and nanofibres. 225th National Meeting of the American-Chemical-Society, New Orleans Louisiana, Mar 23-27, 2003. WASHINGTON: AMER CHEMICAL SOC. |
2003 Journal Article A cyclic metallopeptide induces alpha helicity in short peptide fragments of thermolysinKelso, Michael J., Hoang, Huy N., Oliver, Warren, Sokolenko, Nikolai, March, Darren R., Appleton, Trevor G. and Fairlie, David P. (2003). A cyclic metallopeptide induces alpha helicity in short peptide fragments of thermolysin. Angewandte Chemie International Edition, 42 (4), 421-424. doi: 10.1002/anie.200390128 |
2003 Conference Publication Short peptide alpha helices induced by multiple metal clipsHoang, Huy N., Bryant, Gavin K., Kelso, Micheal J., Beyer, Renee L., Appleton, Trevor G. and Fairlie, David P. (2003). Short peptide alpha helices induced by multiple metal clips. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19-23 July 2003. New York, USA: Elsevier. doi: 10.1016/S0162-0134(03)80638-4 |
2003 Journal Article Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophilesStoermer, M. J., Butler, D. N., Warrener, R. N., Weerasuria, K. D. V. and Fairlie, D. P. (2003). Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles. Chemistry-a European Journal, 9 (9), 2068-2071. doi: 10.1002/chem.200204619 |
2003 Conference Publication Helix inducing metal clips in short peptidesBeyer, R. L., Kelso, M. J., Hoang, H. N., Appleton, T. G. and Fairlie, D. (2003). Helix inducing metal clips in short peptides. Proceedings of the First International Symposium on Biomolecuy, Awaji, Japan, 2-5 December, 2003. Tokyo, Japan: Maruzen Co. Ltd.. |
2003 Journal Article Conformationally homogeneous cyclic tetrapeptides: Useful new three-dimensional scaffoldsGlenn, MP, Kelso, MJ, Tyndall, JDA and Fairlie, DP (2003). Conformationally homogeneous cyclic tetrapeptides: Useful new three-dimensional scaffolds. Journal of The American Chemical Society, 125 (3), 640-641. doi: 10.1021/ja029205t |
2003 Journal Article Tumor cell-specific cytotoxicity by targeting cell cycle checkpointsWarrener, R, Beamish, H, Burgess, A, Waterhouse, NJ, Giles, N, Fairlie, DP and Gabrielli, B (2003). Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints. Faseb Journal, 17 (9), 1550-1570. doi: 10.1096/fj.02-1003fje |
2003 Journal Article Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraintsLucke, AJ, Tyndall, JDA, Singh, Y and Fairlie, DP (2003). Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints. Journal of Molecular Graphics & Modelling, 21 (5), 341-355. doi: 10.1016/S1093-3263(02)00181-X |
2003 Conference Publication Short peptide alpha helices induced by multiple metal clipsHoang, Huy N., Bryant, Gavin K., Kelso, Micheal J., Beyer, Renee L., Appleton, Trevor G. and Fairlie, David P. (2003). Short peptide alpha helices induced by multiple metal clips. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19-23 July, 2003. New York, USA: Elsevier. doi: 10.1016/S0162-0134(03)80638-4 |
2003 Conference Publication Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin AGahan, Lawrence R., Cusack, Rodney M., Grondahl, Lisbeth H., Fairlie, David P. and Hanson, Graeme R. (2003). Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin A. 11th International Conference on Biological Inorganic Chemistry, New York, USA, 19-23July, 2003. New York, USA: Elseiver. doi: 10.1016/S0162-0134(03)80624-4 |
2003 Journal Article Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashionWilliamson, A. L., Brindley, P. J., Abbenante, G., Datu, B. J. D., Prociv, P., Berry, C., Girdwood, K., Pritchard, D. I., Fairlie, D. P., Hotez, P. J., Zhan, B. and Loukas, A. (2003). Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. Journal of Infectious Diseases, 187 (3), 484-494. doi: 10.1086/367708 |