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2001

Journal Article

Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor

Cain, S. A., Woodruff, T. M., Taylor, S. M., Fairlie, D. P., Sanderson, S. D. and Monk, P. N. (2001). Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor. Biochemical Pharmacology, 61 (12), 1571-1579. doi: 10.1016/S0006-2952(01)00608-6

Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor

2001

Conference Publication

Metal clips for folding peptides

Appleton, T. G., Hoang, H. N., Fairlie, D., Kelso, M. and Bryant, G. K. (2001). Metal clips for folding peptides. World Chemistry Congress, Brisbane, 1-6 July, 2001.

Metal clips for folding peptides

2001

Conference Publication

Construction and characterization of the dengue 2 virus NS3 protease and its mutants

Fang, N., Arakaki, T., Fairlie, D., Martin, J. L. and Young, P. R. (2001). Construction and characterization of the dengue 2 virus NS3 protease and its mutants. 1st Australian Virology Group Meeting, Fraser Island, Qld, 5-9 December, 2001.

Construction and characterization of the dengue 2 virus NS3 protease and its mutants

2001

Conference Publication

A new C5a receptor antagonist inhibits monoarticular arthritis in the rat

Woodruff, T. M., Shiels, I. A., Fairlie, D. and Taylor, S. M. (2001). A new C5a receptor antagonist inhibits monoarticular arthritis in the rat. Complement Assoc. Diseases, Animal Models & Ther. Workshop, Santorini, Greece, 10-14 October, 2001. Aegean Conferences.

A new C5a receptor antagonist inhibits monoarticular arthritis in the rat

2001

Journal Article

Preface

Fairlie, D. P. (2001). Preface. Current Medicinal Chemistry, 8 (8) doi: 10.2174/0929867013372724

Preface

2000

Journal Article

An efficient Fmoc strategy for the rapid synthesis of peptide para-nitroanilides

Abbenante, J., Leung, D., Bond, T. J. and Fairlie, D. P. (2000). An efficient Fmoc strategy for the rapid synthesis of peptide para-nitroanilides. Letters in Peptide Science, 7 (6), 347-351. doi: 10.1023/A:1013016323676

An efficient Fmoc strategy for the rapid synthesis of peptide para-nitroanilides

2000

Journal Article

A new small molecule C5a receptor antagonist inhibits the reverse- passive Arthus reaction and endotoxic shock in rats

Strachan, Anna J., Woodruff, Trent M., Haaima, Gerald, Fairlie, David P. and Taylor, Stephen M. (2000). A new small molecule C5a receptor antagonist inhibits the reverse- passive Arthus reaction and endotoxic shock in rats. Journal of Immunology, 164 (12), 6560-6565. doi: 10.4049/jimmunol.164.12.6560

A new small molecule C5a receptor antagonist inhibits the reverse- passive Arthus reaction and endotoxic shock in rats

2000

Journal Article

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells

Qiu, Ling, Burgess, Andrew, Fairlie, David P., Leonard, Helen, Parsons, Peter G. and Gabrielli, Brian G. (2000). Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells. Molecular Biology of the Cell, 11 (6), 2069-2083. doi: 10.1091/mbc.11.6.2069

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells

2000

Journal Article

Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)

Poulsen, Sally-Ann, Watson, Andrew A., Fairlie, David P. and Craik, David J. (2000). Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F). Journal of Structural Biology, 130 (2-3), 142-152. doi: 10.1006/jsbi.2000.4267

Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)

2000

Journal Article

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents Anna Walduck, Mike J. Kelso, David P. Fairlie, Allan Saul, Peter G. Parsons

Andrews, Kathy T., Walduck, Anna, Kelso, Mike J., Fairlie, David P., Saul, Allan and Parsons, Peter G. (2000). Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents Anna Walduck, Mike J. Kelso, David P. Fairlie, Allan Saul, Peter G. Parsons. International Journal for Parasitology, 30 (6), 761-768. doi: 10.1016/S0020-7519(00)00043-6

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents Anna Walduck, Mike J. Kelso, David P. Fairlie, Allan Saul, Peter G. Parsons

2000

Conference Publication

Complement and inflammation: New antagonists of C5a receptors.

Fairlie, DP (2000). Complement and inflammation: New antagonists of C5a receptors.. WASHINGTON: AMER CHEMICAL SOC.

Complement and inflammation: New antagonists of C5a receptors.

2000

Journal Article

Protease inhibitors: Current status and future prospects

Leung, D., Abbenante, G. and Fairlie, D. P. (2000). Protease inhibitors: Current status and future prospects. Journal of Medicinal Chemistry, 43 (3), 305-341. doi: 10.1021/jm990412m

Protease inhibitors: Current status and future prospects

2000

Journal Article

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site

Abbenante, G., Kovacs, D. M., Leung, D. L., Craik, D. J., Tanzi, R. E. and Fairlie, D. P. (2000). Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site. Biochemical And Biophysical Research Communications, 268 (1), 133-135. doi: 10.1006/bbrc.2000.2098

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site

2000

Journal Article

Cell phenotype as a target of drug therapy in chronic inflammatory diseases

Shiels, I. A., Taylor, S. M. and Fairlie, D. P. (2000). Cell phenotype as a target of drug therapy in chronic inflammatory diseases. Medical Hypotheses, 54 (2), 193-197. doi: 10.1054/mehy.1999.0017

Cell phenotype as a target of drug therapy in chronic inflammatory diseases

2000

Conference Publication

Towards Arginine Mimetics

Stoermer, Martin and Fairlie, David (2000). Towards Arginine Mimetics. The First Brisbane Biological and Organic Chemistry Symposium, Griifith University, Brisbane, Queensland, Australia, 27th November 2000. doi: 10.6084/m9.figshare.7836131

Towards Arginine Mimetics

2000

Journal Article

Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding

Cusack, R. M., Grondahl, L., Abbenante, G., Fairlie, D. P., Gahan, L. R., Hanson, G. R. and Hambley, T. W. (2000). Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding. Journal of The Chemical Society-perkin Transactions 2 (2), 323-331. doi: 10.1039/a906090a

Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding

2000

Journal Article

Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing

Fairlie, D. P., Tyndall, J. D. A., Reid, R. C., Wong, A. K., Abbenante, G., Scanlon, M. J., March, D. R., Bergman, D. A., Chai, C. L. L. and Burkett, B. A. (2000). Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing. Journal of Medicinal Chemistry, 43 (7), 1271-1281. doi: 10.1021/jm990315t

Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing

2000

Conference Publication

Coordination with Pd(en)2+ imposes an a-helical structure on a pentapeptide

Appleton, T. G., Hoang, H. N. and Fairlie, D. (2000). Coordination with Pd(en)2+ imposes an a-helical structure on a pentapeptide. Pacifichem 2000, Honolulu, Hawaii, 14-19 December, 2000. American Chemical Society.

Coordination with Pd(en)2+ imposes an a-helical structure on a pentapeptide

2000

Journal Article

Regulators of the anaphylatoxin C5a

Taylor, SM and Fairlie, DP (2000). Regulators of the anaphylatoxin C5a. Expert Opinion in Therapeutic Patents, 10 (4), 449-458. doi: 10.1517/13543776.10.4.449

Regulators of the anaphylatoxin C5a

2000

Journal Article

Characterization of copper interactions with alzheimer amyloid bpeptides: Identification of an attomolar-affinity copper binding site on Amyloid 1-42

Atwood, C. S., Scarpa, R. C., Huang, X., Moir, R. D., Jones, W. D., Fairlie, D. P., Tanzi, R. E. and Bush, A. I. (2000). Characterization of copper interactions with alzheimer amyloid bpeptides: Identification of an attomolar-affinity copper binding site on Amyloid 1-42. Journal of Neurochemistry, 75 (3), 1219-1233. doi: 10.1046/j.1471-4159.2000.0751219.x

Characterization of copper interactions with alzheimer amyloid bpeptides: Identification of an attomolar-affinity copper binding site on Amyloid 1-42