|
2000 Conference Publication Coordination with Pd(en)2+ imposes an a-helical structure on a pentapeptideAppleton, T. G., Hoang, H. N. and Fairlie, D. (2000). Coordination with Pd(en)2+ imposes an a-helical structure on a pentapeptide. Pacifichem 2000, Honolulu, Hawaii, 14-19 December, 2000. American Chemical Society. |
|
2000 Journal Article Regulators of the anaphylatoxin C5aTaylor, SM and Fairlie, DP (2000). Regulators of the anaphylatoxin C5a. Expert Opinion in Therapeutic Patents, 10 (4), 449-458. doi: 10.1517/13543776.10.4.449 |
|
2000 Journal Article Characterization of copper interactions with alzheimer amyloid bpeptides: Identification of an attomolar-affinity copper binding site on Amyloid 1-42Atwood, C. S., Scarpa, R. C., Huang, X., Moir, R. D., Jones, W. D., Fairlie, D. P., Tanzi, R. E. and Bush, A. I. (2000). Characterization of copper interactions with alzheimer amyloid bpeptides: Identification of an attomolar-affinity copper binding site on Amyloid 1-42. Journal of Neurochemistry, 75 (3), 1219-1233. doi: 10.1046/j.1471-4159.2000.0751219.x |
|
2000 Journal Article The first solution structure of a single a-helical turn. A pentapeptide a -Helix stabilized by a metal clipKelso, M. J., Hoang, H. N., Appleton, T. G. and Fairlie, D. (2000). The first solution structure of a single a-helical turn. A pentapeptide a -Helix stabilized by a metal clip. Journal of Americal Chemical Society, 122 (42), 10488-10489. doi: 10.1021/ja002416i |
|
2000 Journal Article Small peptides do not inhibit human non-pancreatic secretory phospholipase-A 2 (Type IIA)Clark, C. I., Reid, R. C., McGeary, R. P., Schafer, K. and Fairlie, D. P. (2000). Small peptides do not inhibit human non-pancreatic secretory phospholipase-A 2 (Type IIA). Bioichemistry BIophysical Research Communications, 274 (3), 831-834. doi: 10.1006/bbrc.2000.3221 |
|
2000 Journal Article A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in ratsStrachan, A. J., Woodruff, T.M., Haaima, G., Fairlie, D. P. and Taylor, S. M. (2000). A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in rats. Journal of Immunology, 164 (4), 6560-6565. |
|
2000 Conference Publication The reaction between metal ions and short peptidesHoang, H. N., Appleton, T. G. and Fairlie, D. (2000). The reaction between metal ions and short peptides. IC2000/11RACIC, Canberra, 6-11 Feb, 2000. |
|
2000 Journal Article Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production In Vitro by a new C5a receptor antagonistHaynes, DR, Harkin, DG, Bignold, LP, Hutchens, MJ, Taylor, SM and Fairlie, DP (2000). Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production In Vitro by a new C5a receptor antagonist. Biochemical Pharmacology, 60 (5), 729-733. doi: 10.1016/S0006-2952(00)00361-0 |
|
2000 Conference Publication Metallopeptides in Alzheimer's DiseaseHanson, G. R., Bush, A. R. I., Fairlie, D. and Tyndall, J. (2000). Metallopeptides in Alzheimer's Disease. Brisbane Inorganic Chemistry Symposium, Dept of Chemistry, Uni of Queensland, 30 November 2000. Brisbane (UQ): Dept of Chemistry, UQ. |
|
2000 Journal Article Is oxidative damage by b- amyloid and prion peptides mediated by hydrogen atom transfer from glycine a-carbon to methionine sulfur within b- sheets?Rauk, A., Armstrong, D. A. and Fairlie, D. P. (2000). Is oxidative damage by b- amyloid and prion peptides mediated by hydrogen atom transfer from glycine a-carbon to methionine sulfur within b- sheets?. Journal of American Chemical Society, 122 (40), 9761-9767. doi: 10.1021/ja994436u |
|
2000 Conference Publication Expression and characterization of a catalytically active form of the Dengue virus NS3 proteaseYoung, P. R., Fang, N., Leung, D., Arakaki, T., Fairlie, D. and Martin, J. L. (2000). Expression and characterization of a catalytically active form of the Dengue virus NS3 protease. 1st Int Conf on Dengue and Dengue Haemorrhagic Fever, Chiang Mai, Thailand, 20-24 Nov, 2000. |
|
2000 Journal Article Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 proteaseTyndall, J. D. A., Reid, R. C., Tyssen, D. P., Jardine, D. K., Todd, B., Passmore, M., March, D. R., Pattenden, L., Bergman, D. A., Alewood, D., Hu, S., Alewood, P.F., Birch, C. J., Martin, J. L. and Fairlie, D. (2000). Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. Journal of Medicinal Chemistry, 43 (19), 3495-3504. doi: 10.1021/jm000013n |
|
1999 Journal Article Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reductionHuang, XD, Cuajungco, MP, Atwood, CS, Hartshorn, MA, Tyndall, JDA, Hanson, GR, Stokes, KC, Leopold, M, Multhaup, G, Goldstein, LE, Scarpa, RC, Saunders, AJ, Lim, J, Moir, RD, Glabe, C, Bowden, EF, Masters, CL, Fairlie, DP, Tanzi, RE and Bush, AI (1999). Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reduction. Journal of Biological Chemistry, 274 (52), 37111-37116. doi: 10.1074/jbc.274.52.37111 |
|
1999 Journal Article Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.Brinkworth, R. I., Fairlie, D., Leung, D. and Young, P. R. (1999). Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.. Journal of General Virology, 80 (5), 1167-1177. doi: 10.1099/0022-1317-80-5-1167 |
|
1999 Journal Article Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the ratShort, Anna, Wong, Allan K., Finch, Angela M., Haaima, Gerald, Shiels, Ian A., Fairlie, David P. and Taylor, Stephen M. (1999). Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat. British Journal of Pharmacology, 126 (2), 551-554. doi: 10.1038/sj.bjp.0702338 |
|
1999 Conference Publication Homology model of the dengue 2 virus NS3 protease: Interactions with NS2B co-factorWhite, H., Young, P. R., Brinkworth, R. I., Fairlie, D. and Leung, D. D. (1999). Homology model of the dengue 2 virus NS3 protease: Interactions with NS2B co-factor. XIth International Congress of Virology, Sydney, 9-13 August 1999. Sydney: International Union of Microbiological Societies. |
|
1999 Journal Article Facile and steroselective condensation of acetone with ammonia ligands on cobalt ( III):structure of a N-bonded cyanate complex containing the 2-methyl-2-amino-4-imino-pentane ligandFairlie, D., Turner, M., Byriel, K., McKeon, J. A. and Jackson, G. W. (1999). Facile and steroselective condensation of acetone with ammonia ligands on cobalt ( III):structure of a N-bonded cyanate complex containing the 2-methyl-2-amino-4-imino-pentane ligand. Inorganica Chimica Acta, 290 (2), 133-138. doi: 10.1016/S0020-1693(99)00110-3 |
|
1999 Journal Article Pharmacological characterization of antagonists of the C5a receptorPaczkowski, NJ, Finch, AM, Whitmore, JB, Short, AJ, Wong, AK, Monk, PN, Cain, SA, Fairlie, DP and Taylor, SM (1999). Pharmacological characterization of antagonists of the C5a receptor. British Journal of Pharmacology, 128 (10), 1461-1466. doi: 10.1038/sj.bjp.0702938 |
|
1999 Other Outputs Cyclic agonists and antagonists of c5a receptors and g protein-coupled receptorsFairlie, David, Taylor, Stephen Maxwell, Finch, Angela Monique and Wong, Allan (1999). Cyclic agonists and antagonists of c5a receptors and g protein-coupled receptors. WO/1999/000406. |
|
1999 Journal Article Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patellaGrondahl, L., Sokolenko, N., Abbenante, G., Fairlie, D. P., Hanson, G. R. and Gahan, L. R. (1999). Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patella. Journal of The Chemical Society-dalton Transactions (8), 1227-1234. doi: 10.1039/a808836e |
