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2003

Conference Publication

Short peptide alpha helices induced by multiple metal clips

Hoang, Huy N., Bryant, Gavin K., Kelso, Micheal J., Beyer, Renee L., Appleton, Trevor G. and Fairlie, David P. (2003). Short peptide alpha helices induced by multiple metal clips. 11th International Conference on Biological Inorganic Chemistry, Cairns, Australia, 19-23 July, 2003. New York, USA: Elsevier. doi: 10.1016/S0162-0134(03)80638-4

Short peptide alpha helices induced by multiple metal clips

2003

Conference Publication

Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin A

Gahan, Lawrence R., Cusack, Rodney M., Grondahl, Lisbeth H., Fairlie, David P. and Hanson, Graeme R. (2003). Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin A. 11th International Conference on Biological Inorganic Chemistry, New York, USA, 19-23July, 2003. New York, USA: Elseiver. doi: 10.1016/S0162-0134(03)80624-4

Studies of the interaction of potassium(I), calcium(II), magnesium(II) and copper(II) with cyclosporin A

2003

Journal Article

Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion

Williamson, A. L., Brindley, P. J., Abbenante, G., Datu, B. J. D., Prociv, P., Berry, C., Girdwood, K., Pritchard, D. I., Fairlie, D. P., Hotez, P. J., Zhan, B. and Loukas, A. (2003). Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. Journal of Infectious Diseases, 187 (3), 484-494. doi: 10.1086/367708

Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion

2003

Journal Article

D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activity

Hansford, Karl A., Reid, Robert C., Clark, Chris I., Tyndall, Joel D. A., Whitehouse, Michael W., Guthrie, Tom, McGeary, Ross P., Schafer, Karl, Martin, Jennifer L. and Fairlie, David P. (2003). D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activity. Chembiochem, 4 (2-3), 181-185. doi: 10.1002/cbic.200390029

D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activity

2003

Conference Publication

Template-assembled peptide loops, helices, sheets, and nanofibers

Fairlie, David P ., Singh, Yogendra, Sharpe, Philip and Stoermer, Martin (2003). Template-assembled peptide loops, helices, sheets, and nanofibers. 225th ACS National Meeting, New Orleans, LA, United States, 23-27 March 2003.

Template-assembled peptide loops, helices, sheets, and nanofibers

2003

Journal Article

A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats

Arumugam, T. V., Shiels, I. A., Strachan, A. J., Abbenante, G., Fairlie, D. P. and Taylor, S. M. (2003). A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. Kidney International, 63 (1), 134-142. doi: 10.1046/j.1523-1755.2003.00737.x

A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats

2003

Book Chapter

Current approaches to peptidomimetics

Kelso, M. J. and Fairlie, D. (2003). Current approaches to peptidomimetics. Molecular Pathomechanisms and New Trends in Drug Research. (pp. 579-598) edited by I. Toth and G. Keri. London and New York: Taylor and Francis.

Current approaches to peptidomimetics

2002

Journal Article

Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat

Woodruff, Trent M., Strachan, Anna J., Dryburgh, Nathan, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat. Arthritis and Rheumatism, 46 (9), 2476-2485. doi: 10.1002/art.10449

Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat

2002

Journal Article

Cleavage of hemoglobin by hookworm cathespin D aspartic proteases and its potential contribution to host specificity

Williamson, Angela L., Brindley, Paul J., Abbenante, Giovanni, Prociv, Paul, Berry, Colin, Girdwood, Karen, Pritchard, David I., Fairlie, David P., Hotez, Peter J., Dalton, John P. and Loukas, Alex C. (2002). Cleavage of hemoglobin by hookworm cathespin D aspartic proteases and its potential contribution to host specificity. The FASEB Journal, 16 (10), 1458-1460. doi: 10.1096/fj.02-0181fje

Cleavage of hemoglobin by hookworm cathespin D aspartic proteases and its potential contribution to host specificity

2002

Conference Publication

Palladium induced alpha helicity in short peptides.

Kelso, MJ, Hoang, HN, Appleton, TG and Fairlie, DP (2002). Palladium induced alpha helicity in short peptides.. WASHINGTON: AMER CHEMICAL SOC.

Palladium induced alpha helicity in short peptides.

2002

Journal Article

Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine

Arumugam, Thiruma V., Shiels, Ian A., Woodruff, Trent M., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine. Journal of Surgical Research, 103 (2), 260-267. doi: 10.1006/jsre.2002.6369

Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine

2002

Other Outputs

Compounds and inhibitors of phospholipases

Reid, Robert C., Clark, Christopher I., Hansford, Karl, Stoermer, Martin J., McGeary, Ross P. and Fairlie, David P. (2002). Compounds and inhibitors of phospholipases. WO0208189.

Compounds and inhibitors of phospholipases

2002

Journal Article

Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (vol 134, pg 1778, 2001)

Strachan, Anna J., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (vol 134, pg 1778, 2001). British Journal of Pharmacology, 135 (2), 579-580. doi: 10.1038/sj.bjp.0704531

Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (vol 134, pg 1778, 2001)

2002

Journal Article

Mimetics of the peptide b-strand

Glenn, M. P. and Fairlie, D. P. (2002). Mimetics of the peptide b-strand. Mini reviews in Medicinal Chemistry, 2, 433-445.

Mimetics of the peptide b-strand

2002

Journal Article

Mimetics of the peptide beta-strand.

Glenn M.P. and Fairlie D.P. (2002). Mimetics of the peptide beta-strand.. Mini reviews in medicinal chemistry, 2 (5), 433-445.

Mimetics of the peptide beta-strand.

2002

Journal Article

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents

Reid, RC, Kelso, MJ, Scanlon, MJ and Fairlie, DP (2002). Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents. Journal of The American Chemical Society, 124 (20), 5673-5683. doi: 10.1021/ja0256461

Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents

2002

Journal Article

Synthesis and structural properties of patellamide a derivatives and their copper(II) compounds

Bernhardt, P. V., Comba, P., Fairlie, D. P., Gahan, L. R., Hanson, G. R. and Lotzbeyer, L. (2002). Synthesis and structural properties of patellamide a derivatives and their copper(II) compounds. Chemistry-a European Journal, 8 (7), 1527-1536. doi: 10.1002/1521-3765(20020402)8:73.3.CO;2-6

Synthesis and structural properties of patellamide a derivatives and their copper(II) compounds

2002

Journal Article

Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography

Arakaki, T. L., Fang, N. X., Fairlie, D. P., Young, P. R. and Martin, J. L. (2002). Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography. Protein Expression And Purification, 25 (2), 241-247. doi: 10.1016/S1046-5928(02)00005-0

Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography

2002

Journal Article

beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity

Glenn, MP, Pattenden, LK, Reid, RC, Tyssen, DP, Tyndall, JDA, Birch, CJ and Fairlie, DP (2002). beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity. Journal of Medicinal Chemistry, 45 (2), 371-381. doi: 10.1021/jm010414i

beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity

2002

Journal Article

Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III)

Fairlie, DP, Dutton, BH, Mckeon, JA and Jackson, WG (2002). Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III). Inorganic Reaction Mechanisms, 4 (3-4), 197-208. doi: 10.1080/1028662021000062626

Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III)