Professor James Fraser
Professor

James Fraser

Email: 
Phone: 
+61 7 336 54868

Availability

Professor James Fraser is:
Available for supervision

Fields of research

Genetics Medical microbiology Microbiology

Qualifications

  • Bachelor (Honours) of Science (Advanced), University of Melbourne
  • Doctor of Philosophy, unknown

Search Professor James Fraser’s works on UQ eSpace

102 works between 1984 and 2024
All (102) Journal Article (94) Book Chapter (2) Conference Publication (6)

41 - 60 of 102 works

2016

Conference Publication

Complex Multi‐Enhancer Contacts Captured By Genome Architecture Mapping, A Novel Ligation‐Free Approach

Pombo, Ana, Beagrie, Robert A., Scialdone, Antonio, Schueler, Markus, Chotalia, Mita, Xie, Sheila Q., Kraemer, Dorothee, de Santiago, Ines, Fraser, James, Dostie, Josee, Game, Laurence, Dillon, Niall, Edwards, Paul A.W. and Nicodemi, Mario (2016). Complex Multi‐Enhancer Contacts Captured By Genome Architecture Mapping, A Novel Ligation‐Free Approach. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.99.3

Complex Multi‐Enhancer Contacts Captured By Genome Architecture Mapping, A Novel Ligation‐Free Approach

2016

Journal Article

Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase. Angewandte Chemie, 128 (13), 4319-4323. doi: 10.1002/ange.201511985

Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase

2016

Journal Article

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase. Angewandte Chemie - International Edition, 55 (13), 4247-4251. doi: 10.1002/anie.201511985

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase

2015

Journal Article

Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

Gerstein, Aleeza C., Fu, Man Shun, Mukaremera, Liliane, Li, Zhongming, Ormerod, Kate L., Fraser, James A, Berman, Judith and Nielsen, Kirsten (2015). Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation. mBio, 6 (5) e01340-15, e01340-15. doi: 10.1128/mBio.01340-15

Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

2015

Journal Article

Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients

Ormerod, Kate L., George, Narelle M., Fraser, James A., Wainwright, Claire and Hugenholtz, Philip (2015). Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients. PeerJ, 3 (9) e1223, e1223.1-e1223.27. doi: 10.7717/peerj.1223

Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients

2015

Journal Article

Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum

Rees, Karlee A., Bermudez, Cindy, Edwards, David J., Elliott, Alysha G., Ripen, Jovita E., Seta, Cynthia, Huang, Johnny X., Cooper, Matthew A., Fraser, James A., Yeo, Tiong C. and Butler, Mark S. (2015). Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum. Journal of Natural Products, 78 (8), 2141-2144. doi: 10.1021/acs.jnatprod.5b00410

Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum

2015

Journal Article

Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane

Taniguti, Lucas M., Schaker, Patricia D. C., Benevenuto, Juliana, Peters, Leila P., Carvalho, Giselle, Palhares, Alessandra, Quecine, Maria C., Nunes, Filipe R. S., Kmit, Maria C. P., Wai, Alvan, Hausner, Georg, Aitken, Karen S., Berkman, Paul J., Fraser, James A., Moolhuijzen, Paula M., Coutinho, Luiz L., Creste, Silvana, Vieira, Maria L. C., Kitajima, João P. and Monteiro-Vitorello, Claudia B. (2015). Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane. PLoS One, 10 (6) e0129318, e0129318. doi: 10.1371/journal.pone.0129318

Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane

2015

Journal Article

Rethinking the targets for antifungal development

Chitty, Jessica L. and Fraser, James A. (2015). Rethinking the targets for antifungal development. Microbiology Australia, 36 (2), 88-89. doi: 10.1071/MA15028

Rethinking the targets for antifungal development

2015

Journal Article

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.

Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Schulz, Benjamin L. and Fraser, James A. (2015). A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.. PLoS One, 10 (4) e0122916, e0122916-e0122916. doi: 10.1371/journal.pone.0122916

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.

2014

Journal Article

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

Kwon-Chung, Kyung J., Fraser, James A., Doering, Tamara L., Wang, Zhuo A., Janbon, Guilhem, Idnurm, Alexander and Bahn, Yong-Sun (2014). Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis. Cold Spring Harbor Perspectives in Medicine, 4 (7), a019760.1-a019760.27. doi: 10.1101/cshperspect.a019760

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

2014

Journal Article

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

Janbon, Guilhem, Ormerod, Kate L., Paulet, Damien, Byrnes III, Edmond J., Yadav, Vikas, Chatterjee, Gautam, Mullapudi, Nandita, Hon, Chung-Chau, Billmyre, R. Blake, Brunel, François, Bahn, Yong-Sun, Chen, Weidong, Chen, Yuan, Chow, Eve W. L., Coppée, Jean-Yves, Floyd-Averette, Anna, Gaillardin, Claude, Gerik, Kimberly J., Goldberg, Jonathan, Gonzalez-Hilarion, Sara, Gujja, Sharvari, Hamlin, Joyce L., Hsueh, Yen-Ping, Ianiri, Giuseppe, Jones, Steven, Kodira, Chinnappa D., Kozubowski, Lukasz, Lam, Woei, Marra, Marco ... Dietrich, Fred S. (2014). Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genetics, 10 (4) e1004261, e1004261.1-e1004261.26. doi: 10.1371/journal.pgen.1004261

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

2014

Journal Article

Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA

Hunter, Cameron C., Siebert, Kendra S., Downes, Damien J., Wong, Koon Ho, Kreutzberger, Sara D., Fraser, James A., Clarke, David F., Hynes, Michael J., Davis, Meryl A. and Todd, Richard B. (2014). Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA. Eukaryotic Cell, 13 (4), 527-538. doi: 10.1128/EC.00040-14

Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA

2014

Conference Publication

Enhancing the complementation process in Cryptococcus neoformans

Arras, S. D. M. and Fraser, J. A. (2014). Enhancing the complementation process in Cryptococcus neoformans. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

Enhancing the complementation process in Cryptococcus neoformans

2014

Conference Publication

The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencing

Ormerod, K. L., Byrnes, E. J., III, Wood, I. A., Lodge, J. K., Heitman, J. and Fraser, J. A. (2014). The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencing. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

The H99 family tree: variation in the common laboratory reference strains of Cryptococcus neoformans var. grubii characterised through whole-genome sequencing

2014

Conference Publication

Purine biosynthetic enzymes as antifungal drug targets

Blundell, R. B., Arras, S. D. M., Williams, S. J. and Fraser, J. A. (2014). Purine biosynthetic enzymes as antifungal drug targets. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

Purine biosynthetic enzymes as antifungal drug targets

2013

Journal Article

Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans

Ormerod, Kate L. and Fraser, James A. (2013). Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans. PLoS Pathogens, 9 (12) e1003764, 1-4. doi: 10.1371/journal.ppat.1003764

Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans

2013

Journal Article

Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans

Blundell, Ross D., Williams, Simon J., Morrow, Carl A., Ericsson, Daniel J., Kobe, Bostjan and Fraser, James A. (2013). Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69 (Pt. 9), 1033-1036. doi: 10.1107/S1744309113021921

Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans

2013

Journal Article

Secondary metabolites of the sponge-derived fungus Acremonium persicinum

Suciati, Fraser, James A., Lambert, Lynette K., Pierens, Gregory K., Bernhardt, Paul V. and Garson, Mary J. (2013). Secondary metabolites of the sponge-derived fungus Acremonium persicinum. Journal of Natural Products, 76 (8), 1432-1440. doi: 10.1021/np4002114

Secondary metabolites of the sponge-derived fungus Acremonium persicinum

2013

Journal Article

Nitrogen regulation of virulence in clinically prevalent fungal pathogens

Lee, I. Russel, Morrow, Carl A. and Fraser, James A. (2013). Nitrogen regulation of virulence in clinically prevalent fungal pathogens. FEMS Microbiology Letters, 345 (2), 77-84. doi: 10.1111/1574-6968.12181

Nitrogen regulation of virulence in clinically prevalent fungal pathogens

2013

Journal Article

Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?

Morrow, Carl A. and Fraser, James A. (2013). Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?. MBio, 4 (4) e00408-13, e00408-13.1-e00408-13.3. doi: 10.1128/mBio.00408-13

Is the nickel-dependent urease complex of Cryptococcus the pathogen's Achilles' heel?

Past funding

  • 2020 - 2023
    Novel Broad Spectrum Antifungals Active Against Drug Resistant Candida Auris
    NHMRC IDEAS Grants
    Open grant
  • 2019
    A versatile accurate mass, high resolution QTOF mass spectrometer for chemistry and proteomic applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Epifluorescent and live-cell imaging microscopes for the investigation of host-pathogen interactions and for molecular and cellular biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2021
    Microevolution of Cryptococcus neoformans
    NHMRC Project Grant
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Acetohydroxyacid synthase: A new drug target for human fungal pathogens
    NHMRC Project Grant
    Open grant
  • 2014
    A confocal microscope for investigation of live bacterial and viral pathogens and for molecular cell biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2016
    Purine metabolism as an antifungal drug target
    NHMRC Project Grant
    Open grant
  • 2012 - 2013
    IMPDH as an antifungal drug target
    Therapeutic Innovation Australia Limited
    Open grant
  • 2011 - 2014
    Targeting acetohydroxyacid synthase to discover new antifungal agents
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    ResTeach 2010 0.1 FTE School of Chemistry and Molecular Biosciences
    UQ ResTeach
    Open grant
  • 2010 - 2012
    Understanding an exotic disease: Initiation of sex and infection by the sugarcane smut Ustilago scitaminea
    ARC Discovery Projects
    Open grant
  • 2007 - 2010
    Transposable element mobility and chromosomal rearrangement in the fungal pathogen Cryptococcus during human infection
    NHMRC Project Grant
    Open grant

Availability

Professor James Fraser is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Purine biosynthesis as an anti fungal target

    Principal Advisor

    Other advisors: Professor Bostjan Kobe

  • Doctor Philosophy

    The role of the cotranscriptional activator complex SAGA in virulence of Cryptococcus neoformans

    Principal Advisor

    Other advisors: Professor Benjamin Schulz

  • Doctor Philosophy

    Advanced Genetic Toolkit for Cryptococcus neoformans: Iterating Upon Currently Used Techniques in the WHO¿s Top-Ranked Fungal Pathogen

    Principal Advisor

    Other advisors: Associate Professor Nick West

  • Doctor Philosophy

    Resolving a Dichotomy: A Journey between the Laboratory and the Classroom

    Principal Advisor

    Other advisors: Professor Bostjan Kobe

  • Doctor Philosophy

    The Cryptococcus neoformans SAGA: Investigating the SAGA associated Histone acetyltransferase and Deubiquitinase modules opposing influence on virulence

    Principal Advisor

    Other advisors: Professor Benjamin Schulz

  • Doctor Philosophy

    Antifungal agents to target disseminated mycoses

    Principal Advisor

    Other advisors: Dr Kylie Agnew-Francis, Professor Avril Robertson

  • Doctor Philosophy

    Characterising the membrane interactions and cytotoxic activity of the anti-fungal peptide Lactofungin

    Associate Advisor

    Other advisors: Dr Evelyne Deplazes

  • Doctor Philosophy

    Targetting Candida Auris

    Associate Advisor

    Other advisors: Dr Kylie Agnew-Francis, Professor Avril Robertson

  • Doctor Philosophy

    Developing a cell-free, structural model of fungal cell walls

    Associate Advisor

    Other advisors: Dr Evelyne Deplazes

  • Doctor Philosophy

    Targeting Deadly Mycotic Infection

    Associate Advisor

    Other advisors: Dr Kylie Agnew-Francis, Professor Avril Robertson

Completed supervision

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