Professor James Fraser
Professor

James Fraser

Email: 
Phone: 
+61 7 336 54868

Availability

Professor James Fraser is:
Available for supervision

Fields of research

Genetics Medical microbiology Microbiology

Qualifications

  • Bachelor (Honours) of Science (Advanced), University of Melbourne
  • Doctor of Philosophy, Institution to be confirmed

Search Professor James Fraser’s works on UQ eSpace

111 works between 1984 and 2025
All (111) Journal Article (100) Book Chapter (2) Conference Publication (9)

41 - 60 of 111 works

2017

Journal Article

Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]

Borneman, A. R., Forgan, A.H., Kolouchova, R., Fraser, J. A. and Schmidt, S.A. (2017). Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]. G3: Genes, Genomes, Genetics, 7 (1), 319-319. doi: 10.1534/g3.116.036038

Corrigendum: Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of CommercialWine Strains of Saccharomyces cerevisiae [G3 Genes|Genomes|Genetics, 6 (957-971)]

2016

Journal Article

Targeted genome editing via CRISPR in the pathogen Cryptococcus neoformans

Arras, Samantha D. M., Chua, Sheena M. H., Wizrah, Maha S. I., Faint, Joshua A., Yap, Amy S. and Fraser, James A. (2016). Targeted genome editing via CRISPR in the pathogen Cryptococcus neoformans. PloS One, 11 (10) e0164322, e0164322. doi: 10.1371/journal.pone.0164322

Targeted genome editing via CRISPR in the pathogen Cryptococcus neoformans

2016

Journal Article

Chemical inhibitors of non-homologous end joining increase targeted construct integration in Cryptococcus neoformans

Arras, Samantha D. M. and Fraser, James A. (2016). Chemical inhibitors of non-homologous end joining increase targeted construct integration in Cryptococcus neoformans. PLoS One, 11 (9) e0163049, e0163049. doi: 10.1371/journal.pone.0163049

Chemical inhibitors of non-homologous end joining increase targeted construct integration in Cryptococcus neoformans

2016

Journal Article

Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans

Blundell, Ross D., Williams, Simon J., Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Ericsson, Daniel J., Tibrewal, Nidhi, Rohr, Jurgen, Koh, Y. Q. Andre, Kappler, Ulrike, Robertson, Avril A. B., Butler, Mark S., Cooper, Matthew A., Kobe, Bostjan and Fraser, James A. (2016). Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans. ACS Infectious Diseases, 2 (9), 651-663. doi: 10.1021/acsinfecdis.6b00121

Disruption of de novo adenosine triphosphate (ATP) biosynthesis abolishes virulence in Cryptococcus neoformans

2016

Journal Article

Whole genome comparison reveals high levels of inbreeding and strain redundancy across the spectrum of commercial wine strains of Saccharomyces cerevisiae

Borneman, Anthony R., Forgan, Angus H., Kolouchova, Radka, Fraser, James A. and Schmidt, Simon A. (2016). Whole genome comparison reveals high levels of inbreeding and strain redundancy across the spectrum of commercial wine strains of Saccharomyces cerevisiae. G3: Genes, Genomes, Genetics, 6 (4), 957-971. doi: 10.1534/g3.115.025692

Whole genome comparison reveals high levels of inbreeding and strain redundancy across the spectrum of commercial wine strains of Saccharomyces cerevisiae

2016

Journal Article

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F

Beattie, Karren D., Ellwood, Nicola, Kumar, Rohitesh, Yang, Xinzhou, Healy, Peter C., Choomuenwai, Vanida, Quinn, Ronald J., Elliott, Alysha G., Huang, Johnny X., Chitty, Jessica L., Fraser, James A., Cooper, Matthew A. and Davis, Rohan A. (2016). Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F. Phytochemistry, 124, 79-85. doi: 10.1016/j.phytochem.2015.12.014

Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F

2016

Conference Publication

Complex Multi‐Enhancer Contacts Captured By Genome Architecture Mapping, A Novel Ligation‐Free Approach

Pombo, Ana, Beagrie, Robert A., Scialdone, Antonio, Schueler, Markus, Chotalia, Mita, Xie, Sheila Q., Kraemer, Dorothee, de Santiago, Ines, Fraser, James, Dostie, Josee, Game, Laurence, Dillon, Niall, Edwards, Paul A.W. and Nicodemi, Mario (2016). Complex Multi‐Enhancer Contacts Captured By Genome Architecture Mapping, A Novel Ligation‐Free Approach. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.99.3

Complex Multi‐Enhancer Contacts Captured By Genome Architecture Mapping, A Novel Ligation‐Free Approach

2016

Journal Article

Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase. Angewandte Chemie, 128 (13), 4319-4323. doi: 10.1002/ange.201511985

Commercial herbicides can trigger the oxidative inactivation of acetohydroxyacid synthase

2016

Journal Article

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase

Lonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase. Angewandte Chemie - International Edition, 55 (13), 4247-4251. doi: 10.1002/anie.201511985

Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase

2015

Journal Article

Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

Gerstein, Aleeza C., Fu, Man Shun, Mukaremera, Liliane, Li, Zhongming, Ormerod, Kate L., Fraser, James A, Berman, Judith and Nielsen, Kirsten (2015). Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation. mBio, 6 (5) e01340-15, e01340-15. doi: 10.1128/mBio.01340-15

Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

2015

Journal Article

Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients

Ormerod, Kate L., George, Narelle M., Fraser, James A., Wainwright, Claire and Hugenholtz, Philip (2015). Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients. PeerJ, 3 (9) e1223, e1223.1-e1223.27. doi: 10.7717/peerj.1223

Comparative genomics of non-pseudomonal bacterial species colonising paediatric cystic fibrosis patients

2015

Journal Article

Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum

Rees, Karlee A., Bermudez, Cindy, Edwards, David J., Elliott, Alysha G., Ripen, Jovita E., Seta, Cynthia, Huang, Johnny X., Cooper, Matthew A., Fraser, James A., Yeo, Tiong C. and Butler, Mark S. (2015). Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum. Journal of Natural Products, 78 (8), 2141-2144. doi: 10.1021/acs.jnatprod.5b00410

Flemingin-type prenylated chalcones from the sarawak rainforest plant desmodium congestum

2015

Journal Article

Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane

Taniguti, Lucas M., Schaker, Patricia D. C., Benevenuto, Juliana, Peters, Leila P., Carvalho, Giselle, Palhares, Alessandra, Quecine, Maria C., Nunes, Filipe R. S., Kmit, Maria C. P., Wai, Alvan, Hausner, Georg, Aitken, Karen S., Berkman, Paul J., Fraser, James A., Moolhuijzen, Paula M., Coutinho, Luiz L., Creste, Silvana, Vieira, Maria L. C., Kitajima, João P. and Monteiro-Vitorello, Claudia B. (2015). Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane. PLoS One, 10 (6) e0129318, e0129318. doi: 10.1371/journal.pone.0129318

Complete genome sequence of Sporisorium scitamineum and biotrophic interaction transcriptome with sugarcane

2015

Journal Article

Rethinking the targets for antifungal development

Chitty, Jessica L. and Fraser, James A. (2015). Rethinking the targets for antifungal development. Microbiology Australia, 36 (2), 88-89. doi: 10.1071/MA15028

Rethinking the targets for antifungal development

2015

Journal Article

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.

Arras, Samantha D. M., Chitty, Jessica L., Blake, Kirsten L., Schulz, Benjamin L. and Fraser, James A. (2015). A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.. PLoS One, 10 (4) e0122916, e0122916-e0122916. doi: 10.1371/journal.pone.0122916

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans.

2014

Journal Article

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

Kwon-Chung, Kyung J., Fraser, James A., Doering, Tamara L., Wang, Zhuo A., Janbon, Guilhem, Idnurm, Alexander and Bahn, Yong-Sun (2014). Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis. Cold Spring Harbor Perspectives in Medicine, 4 (7), a019760.1-a019760.27. doi: 10.1101/cshperspect.a019760

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

2014

Journal Article

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

Janbon, Guilhem, Ormerod, Kate L., Paulet, Damien, Byrnes III, Edmond J., Yadav, Vikas, Chatterjee, Gautam, Mullapudi, Nandita, Hon, Chung-Chau, Billmyre, R. Blake, Brunel, François, Bahn, Yong-Sun, Chen, Weidong, Chen, Yuan, Chow, Eve W. L., Coppée, Jean-Yves, Floyd-Averette, Anna, Gaillardin, Claude, Gerik, Kimberly J., Goldberg, Jonathan, Gonzalez-Hilarion, Sara, Gujja, Sharvari, Hamlin, Joyce L., Hsueh, Yen-Ping, Ianiri, Giuseppe, Jones, Steven, Kodira, Chinnappa D., Kozubowski, Lukasz, Lam, Woei, Marra, Marco ... Dietrich, Fred S. (2014). Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genetics, 10 (4) e1004261, e1004261.1-e1004261.26. doi: 10.1371/journal.pgen.1004261

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

2014

Journal Article

Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA

Hunter, Cameron C., Siebert, Kendra S., Downes, Damien J., Wong, Koon Ho, Kreutzberger, Sara D., Fraser, James A., Clarke, David F., Hynes, Michael J., Davis, Meryl A. and Todd, Richard B. (2014). Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA. Eukaryotic Cell, 13 (4), 527-538. doi: 10.1128/EC.00040-14

Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA

2014

Conference Publication

Discovering and Manipulating Protein Conformational Heterogeneity and Function

Keedy, Daniel, van den Bedem, Henry, Rettenmaier, Justin, Wells, James and Fraser, James (2014). Discovering and Manipulating Protein Conformational Heterogeneity and Function. 58th Annual Meeting of the Biophysical-Society, San Francisco Ca, Feb 15-19, 2014. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2013.11.3515

Discovering and Manipulating Protein Conformational Heterogeneity and Function

2014

Conference Publication

Enhancing the complementation process in Cryptococcus neoformans

Arras, S. D. M. and Fraser, J. A. (2014). Enhancing the complementation process in Cryptococcus neoformans. 9th International Conference on Cryptococcus and Cryptococcosis, Amsterdam, The Netherlands, 15-19 May 2014. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/myc.12196

Enhancing the complementation process in Cryptococcus neoformans

Past funding

  • 2020 - 2023
    Novel Broad Spectrum Antifungals Active Against Drug Resistant Candida Auris
    NHMRC IDEAS Grants
    Open grant
  • 2019
    A versatile accurate mass, high resolution QTOF mass spectrometer for chemistry and proteomic applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Epifluorescent and live-cell imaging microscopes for the investigation of host-pathogen interactions and for molecular and cellular biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2021
    Microevolution of Cryptococcus neoformans
    NHMRC Project Grant
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Acetohydroxyacid synthase: A new drug target for human fungal pathogens
    NHMRC Project Grant
    Open grant
  • 2014
    A confocal microscope for investigation of live bacterial and viral pathogens and for molecular cell biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2016
    Purine metabolism as an antifungal drug target
    NHMRC Project Grant
    Open grant
  • 2012 - 2013
    IMPDH as an antifungal drug target
    Therapeutic Innovation Australia Limited
    Open grant
  • 2011 - 2014
    Targeting acetohydroxyacid synthase to discover new antifungal agents
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    ResTeach 2010 0.1 FTE School of Chemistry and Molecular Biosciences
    UQ ResTeach
    Open grant
  • 2010 - 2012
    Understanding an exotic disease: Initiation of sex and infection by the sugarcane smut Ustilago scitaminea
    ARC Discovery Projects
    Open grant
  • 2007 - 2010
    Transposable element mobility and chromosomal rearrangement in the fungal pathogen Cryptococcus during human infection
    NHMRC Project Grant
    Open grant

Availability

Professor James Fraser is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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