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Professor Peter Visscher
Professor

Peter Visscher

Email: 
Phone: 
+61 7 344 37045

Overview

Background

Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.

Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.

Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.

Availability

Professor Peter Visscher is:
Not available for supervision

Fields of research

Qualifications

  • Masters (Coursework) of Science, University of Edinburgh
  • Doctor of Philosophy, University of Edinburgh

Research impacts

Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.

Works

Search Professor Peter Visscher’s works on UQ eSpace

803 works between 1987 and 2025

221 - 240 of 803 works

2018

Journal Article

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank

Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006

Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank

2018

Conference Publication

Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology

Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2018). Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology. 27th Annual Meeting of the International Genetic Epidemiology Society (IGES), San Diego, CA, United States, 14-16 October 2018. Hoboken, NJ, United States: John Wiley & Sons.

Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology

2018

Journal Article

Multi-trait analysis of genome-wide association summary statistics using MTAG

Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Magnusson, Patrik, Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M., Laibson, David, Cesarini, David, Neale, Benjamin M., Benjamin, Daniel J., 23andMe Research Team and Social Science Genetic Association Consortium (2018). Multi-trait analysis of genome-wide association summary statistics using MTAG. Nature Genetics, 50 (229+), 229-237. doi: 10.1038/s41588-017-0009-4

Multi-trait analysis of genome-wide association summary statistics using MTAG

2018

Journal Article

Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels

Lupton, Michelle K., Medland, Sarah E., Gordon, Scott D., Goncalves, Tabatha, MacGregor, Stuart, Mackey, David A., Young, Terri L., Duffy, David L., Visscher, Peter M., Wray, Naomi R., Nyholt, Dale R., Bain, Lisa, Ferreira, Manuel A., Henders, Anjali K., Wallace, Leanne, Montgomery, Grant W., Wright, Margaret J. and Martin, Nicholas G. (2018). Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels. Journal of Alzheimer's Disease, 64 (1), 49-54. doi: 10.3233/JAD-171104

Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels

2018

Conference Publication

Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia

Tucci, Serena, McCoy, Rajiv, Vernot, Benjamin, Vohr, Sam, Robinson, Matthew R., Barbieri, Chiara, Fu, Wenqing, Sudoyo, Herawati, Visscher, Peter M., Barbujani, Guido, Akey, Joshua M. and Green, Richard E. (2018). Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia. 87th Annual Meeting of the American-Association-of-Physical-Anthropologists (AAPA), Austin, TX, United States, 11-14 April 2018. Hoboken, NJ, United States: John Wiley & Sons.

Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia

2018

Conference Publication

Signatures of negative selection in the genetic architecture of human complex traits

Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, Mcrae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. 48th Annual Meeting of the Behavior-Genetics-Association (BGA), Boston MA, United States, 20-23 June 2018. New York, NY United States: Springer New York.

Signatures of negative selection in the genetic architecture of human complex traits

2018

Conference Publication

Fine-mapping reveals complex genetic architecture underlying DNA methylation

Chundru, V. Kartik, Marioni, Riccardo E., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2018). Fine-mapping reveals complex genetic architecture underlying DNA methylation. Human Genome Meeting, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications. doi: 10.1186/s40246-018-0138-6

Fine-mapping reveals complex genetic architecture underlying DNA methylation

2018

Journal Article

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Wang, Yunzhang, Karlsson, Robert, Lampa, Erik, Zhang, Qian, Hedman, Åsa K., Almgren, Malin, Almqvist, Catarina, McRae, Allan F., Marioni, Riccardo E., Ingelsson, Erik, Visscher, Peter M., Deary, Ian J., Lind, Lars, Morris, Tiffany, Beck, Stephan, Pedersen, Nancy L. and Hägg, Sara (2018). Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins. Epigenetics, 13 (9), 1-13. doi: 10.1080/15592294.2018.1526028

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

2017

Journal Article

Challenges in understanding common disease

Visscher, Peter M (2017). Challenges in understanding common disease. Genome medicine, 9 (1) 112, 1-4. doi: 10.1186/s13073-017-0506-1

Challenges in understanding common disease

2017

Journal Article

Gene networks associated with non-syndromic intellectual disability

Lee, Soohyun, Rudd, Stephen, Gratten, Jacob, Visscher, Peter M., Prins, Johannes B. and Dawson, Paul A. (2017). Gene networks associated with non-syndromic intellectual disability. Journal of Neurogenetics, 32 (1), 6-14. doi: 10.1080/01677063.2017.1404058

Gene networks associated with non-syndromic intellectual disability

2017

Journal Article

Testing two evolutionary theories of human aging with DNA methylation data

Robins, Chloe, McRae, Allan F., Powell, Joseph E., Wiener, Howard W., Aslibekyan, Stella, Kennedy, Elizabeth M., Absher, Devin M., Arnett, Donna K., Montgomery, Grant W., Visscher, Peter M., Cutler, David J. and Conneely, Karen N. (2017). Testing two evolutionary theories of human aging with DNA methylation data. Genetics, 207 (4), 1547-1560. doi: 10.1534/genetics.117.300217

Testing two evolutionary theories of human aging with DNA methylation data

2017

Journal Article

A genome-wide association study suggests that <i>MAPK14</i> is associated with diabetic foot ulcers

Meng, W., Veluchamy, A., Hebert, H. L., Campbell, A., Colhoun, H. M. and Palmer, C. N. A. (2017). A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. British Journal of Dermatology, 177 (6), 1664-1670. doi: 10.1111/bjd.15787

A genome-wide association study suggests that <i>MAPK14</i> is associated with diabetic foot ulcers

2017

Journal Article

Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity

Hendricks, Audrey E., Bochukova, Elena G., Marenne, Gaelle, Keogh, Julia M., Atanassova, Neli, Bounds, Rebecca, Wheeler, Eleanor, Mistry, Vanisha, Henning, Elana, Koerner, Antje, Muddyman, Dawn, McCarthy, Shane, Hinney, Anke, Hebebrand, Johannes, Scott, Robert A., Langenberg, Claudia, Wareham, Nick J., Surendran, Praveen, Howson, Joanna M., Butterworth, Adam S., Danesh, John, Nordestgaard, Borge G., Nielsen, Sune F., Afzal, Shoaib, Papadia, Sofia, Ashford, Sofie, Garg, Sumedha, Millhauser, Glenn L., Palomino, Rafael I. ... Yang, Jian (2017). Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity. Scientific Reports, 7 (1) 4394, 4394.1-4394.14. doi: 10.1038/s41598-017-03054-8

Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity

2017

Journal Article

Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese

Gratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H. ... Fan, Dongsheng (2017). Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9 (97) 97, 97. doi: 10.1186/s13073-017-0487-0

Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese

2017

Journal Article

Prokaryotic diversity and biogeochemical characteristics of benthic microbial ecosystems at La Brava, a hypersaline lake at Salar de Atacama, Chile

Eugenia Farias, Maria, Cecilia Rasuk, Maria, Gallagher, Kimberley L., Contreras, Manuel, Kurth, Daniel, Beatriz Fernandez, Ana, Poire, Daniel, Novoa, Fernando and Visscher, Pieter T. (2017). Prokaryotic diversity and biogeochemical characteristics of benthic microbial ecosystems at La Brava, a hypersaline lake at Salar de Atacama, Chile. Plos One, 12 (11) e0186867, e0186867. doi: 10.1371/journal.pone.0186867

Prokaryotic diversity and biogeochemical characteristics of benthic microbial ecosystems at La Brava, a hypersaline lake at Salar de Atacama, Chile

2017

Conference Publication

GWAS of educational attainment: phase 3-main results

Okbay, Aysu, Wedow, Robbee, Kong, Edward, Turley, Patrick, Lee, James, Zacher, Meghan, Thom, Kevin, Anh Tuan Nguyen, , Maghzian, Omeed, Linner, Richard Karlsson, Robinson, Matthew, Visscher, Peter, Benjamin, Daniel and Cesarini, David (2017). GWAS of educational attainment: phase 3-main results. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, Jun 28-Jul 01, 2017. NEW YORK: SPRINGER.

GWAS of educational attainment: phase 3-main results

2017

Journal Article

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

2017

Journal Article

Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

Lukowski, Samuel W., Lloyd-Jones, Luke R., Holloway, Alexander, Kirsten, Holger, Hemani, Gibran, Yang, Jian, Small, Kerrin, Zhao, Jing, Metspalu, Andres, Dermitzakis, Emmanouil T., Gibson, Greg, Spector, Timothy D., Thiery, Joachim, Scholz, Markus, Montgomery, Grant W., Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017). Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood. Nature Communications, 8 (483) 483, 483. doi: 10.1038/s41467-017-00473-z

Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

2017

Journal Article

Concepts, estimation and interpretation of SNP-based heritability

Yang, Jian, Zeng, Jian, Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2017). Concepts, estimation and interpretation of SNP-based heritability. Nature Genetics, 49 (9), 1304-1310. doi: 10.1038/ng.3941

Concepts, estimation and interpretation of SNP-based heritability

2017

Journal Article

Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method

Chen, Guo-Bo, Lee, Sang Hong, Montgomery, Grant W., Wray, Naomi R., Visscher, Peter M., Gearry, Richard B., Lawrance, Ian C., Andrews, Jane M., Bampton, Peter, Mahy, Gillian, Bell, Sally, Walsh, Alissa, Connor, Susan, Sparrow, Miles, Bowdler, Lisa M., Simms, Lisa A., Krishnaprasad, Krupa, Radford-Smith, Graham L. and Moser, Gerhard (2017). Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method. BMC Medical Genetics, 18 (1) 94, 94. doi: 10.1186/s12881-017-0451-2

Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method

Funding

Current funding

  • 2019 - 2025
    Causes and consequence of human trait variation
    ARC Australian Laureate Fellowships
    Open grant

Supervision

Availability

Professor Peter Visscher is:
Not available for supervision

Supervision history

Current supervision

  • Doctor Philosophy

    Statistical methods and application to analyses genome and trait data from large biobanks

    Principal Advisor

    Other advisors: Dr Kathryn Kemper, Professor Loic Yengo

  • Doctor Philosophy

    Genetic architecture and evolution of complex traits across populations in humans

    Associate Advisor

    Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng

  • Doctor Philosophy

    Integrating GWAS and molecular QTL data to dissect genetic architecture and improve polygenic prediction

    Associate Advisor

    Other advisors: Dr Jian Zeng

Completed supervision

Media

Enquiries

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