
Overview
Background
Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.
Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.
Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.
Availability
- Professor Peter Visscher is:
- Not available for supervision
Fields of research
Qualifications
- Masters (Coursework) of Science, University of Edinburgh
- Doctor of Philosophy, University of Edinburgh
Research impacts
Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.
Works
Search Professor Peter Visscher’s works on UQ eSpace
2018
Journal Article
Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank
Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006
2018
Conference Publication
Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology
Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2018). Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology. 27th Annual Meeting of the International Genetic Epidemiology Society (IGES), San Diego, CA, United States, 14-16 October 2018. Hoboken, NJ, United States: John Wiley & Sons.
2018
Journal Article
Multi-trait analysis of genome-wide association summary statistics using MTAG
Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Magnusson, Patrik, Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M., Laibson, David, Cesarini, David, Neale, Benjamin M., Benjamin, Daniel J., 23andMe Research Team and Social Science Genetic Association Consortium (2018). Multi-trait analysis of genome-wide association summary statistics using MTAG. Nature Genetics, 50 (229+), 229-237. doi: 10.1038/s41588-017-0009-4
2018
Journal Article
Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels
Lupton, Michelle K., Medland, Sarah E., Gordon, Scott D., Goncalves, Tabatha, MacGregor, Stuart, Mackey, David A., Young, Terri L., Duffy, David L., Visscher, Peter M., Wray, Naomi R., Nyholt, Dale R., Bain, Lisa, Ferreira, Manuel A., Henders, Anjali K., Wallace, Leanne, Montgomery, Grant W., Wright, Margaret J. and Martin, Nicholas G. (2018). Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels. Journal of Alzheimer's Disease, 64 (1), 49-54. doi: 10.3233/JAD-171104
2018
Conference Publication
Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia
Tucci, Serena, McCoy, Rajiv, Vernot, Benjamin, Vohr, Sam, Robinson, Matthew R., Barbieri, Chiara, Fu, Wenqing, Sudoyo, Herawati, Visscher, Peter M., Barbujani, Guido, Akey, Joshua M. and Green, Richard E. (2018). Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia. 87th Annual Meeting of the American-Association-of-Physical-Anthropologists (AAPA), Austin, TX, United States, 11-14 April 2018. Hoboken, NJ, United States: John Wiley & Sons.
2018
Conference Publication
Signatures of negative selection in the genetic architecture of human complex traits
Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, Mcrae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. 48th Annual Meeting of the Behavior-Genetics-Association (BGA), Boston MA, United States, 20-23 June 2018. New York, NY United States: Springer New York.
2018
Conference Publication
Fine-mapping reveals complex genetic architecture underlying DNA methylation
Chundru, V. Kartik, Marioni, Riccardo E., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2018). Fine-mapping reveals complex genetic architecture underlying DNA methylation. Human Genome Meeting, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications. doi: 10.1186/s40246-018-0138-6
2018
Journal Article
Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins
Wang, Yunzhang, Karlsson, Robert, Lampa, Erik, Zhang, Qian, Hedman, Åsa K., Almgren, Malin, Almqvist, Catarina, McRae, Allan F., Marioni, Riccardo E., Ingelsson, Erik, Visscher, Peter M., Deary, Ian J., Lind, Lars, Morris, Tiffany, Beck, Stephan, Pedersen, Nancy L. and Hägg, Sara (2018). Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins. Epigenetics, 13 (9), 1-13. doi: 10.1080/15592294.2018.1526028
2017
Journal Article
Challenges in understanding common disease
Visscher, Peter M (2017). Challenges in understanding common disease. Genome medicine, 9 (1) 112, 1-4. doi: 10.1186/s13073-017-0506-1
2017
Journal Article
Gene networks associated with non-syndromic intellectual disability
Lee, Soohyun, Rudd, Stephen, Gratten, Jacob, Visscher, Peter M., Prins, Johannes B. and Dawson, Paul A. (2017). Gene networks associated with non-syndromic intellectual disability. Journal of Neurogenetics, 32 (1), 6-14. doi: 10.1080/01677063.2017.1404058
2017
Journal Article
Testing two evolutionary theories of human aging with DNA methylation data
Robins, Chloe, McRae, Allan F., Powell, Joseph E., Wiener, Howard W., Aslibekyan, Stella, Kennedy, Elizabeth M., Absher, Devin M., Arnett, Donna K., Montgomery, Grant W., Visscher, Peter M., Cutler, David J. and Conneely, Karen N. (2017). Testing two evolutionary theories of human aging with DNA methylation data. Genetics, 207 (4), 1547-1560. doi: 10.1534/genetics.117.300217
2017
Journal Article
A genome-wide association study suggests that <i>MAPK14</i> is associated with diabetic foot ulcers
Meng, W., Veluchamy, A., Hebert, H. L., Campbell, A., Colhoun, H. M. and Palmer, C. N. A. (2017). A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. British Journal of Dermatology, 177 (6), 1664-1670. doi: 10.1111/bjd.15787
2017
Journal Article
Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity
Hendricks, Audrey E., Bochukova, Elena G., Marenne, Gaelle, Keogh, Julia M., Atanassova, Neli, Bounds, Rebecca, Wheeler, Eleanor, Mistry, Vanisha, Henning, Elana, Koerner, Antje, Muddyman, Dawn, McCarthy, Shane, Hinney, Anke, Hebebrand, Johannes, Scott, Robert A., Langenberg, Claudia, Wareham, Nick J., Surendran, Praveen, Howson, Joanna M., Butterworth, Adam S., Danesh, John, Nordestgaard, Borge G., Nielsen, Sune F., Afzal, Shoaib, Papadia, Sofia, Ashford, Sofie, Garg, Sumedha, Millhauser, Glenn L., Palomino, Rafael I. ... Yang, Jian (2017). Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity. Scientific Reports, 7 (1) 4394, 4394.1-4394.14. doi: 10.1038/s41598-017-03054-8
2017
Journal Article
Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese
Gratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H. ... Fan, Dongsheng (2017). Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9 (97) 97, 97. doi: 10.1186/s13073-017-0487-0
2017
Journal Article
Prokaryotic diversity and biogeochemical characteristics of benthic microbial ecosystems at La Brava, a hypersaline lake at Salar de Atacama, Chile
Eugenia Farias, Maria, Cecilia Rasuk, Maria, Gallagher, Kimberley L., Contreras, Manuel, Kurth, Daniel, Beatriz Fernandez, Ana, Poire, Daniel, Novoa, Fernando and Visscher, Pieter T. (2017). Prokaryotic diversity and biogeochemical characteristics of benthic microbial ecosystems at La Brava, a hypersaline lake at Salar de Atacama, Chile. Plos One, 12 (11) e0186867, e0186867. doi: 10.1371/journal.pone.0186867
2017
Conference Publication
GWAS of educational attainment: phase 3-main results
Okbay, Aysu, Wedow, Robbee, Kong, Edward, Turley, Patrick, Lee, James, Zacher, Meghan, Thom, Kevin, Anh Tuan Nguyen, , Maghzian, Omeed, Linner, Richard Karlsson, Robinson, Matthew, Visscher, Peter, Benjamin, Daniel and Cesarini, David (2017). GWAS of educational attainment: phase 3-main results. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, Jun 28-Jul 01, 2017. NEW YORK: SPRINGER.
2017
Journal Article
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1
2017
Journal Article
Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood
Lukowski, Samuel W., Lloyd-Jones, Luke R., Holloway, Alexander, Kirsten, Holger, Hemani, Gibran, Yang, Jian, Small, Kerrin, Zhao, Jing, Metspalu, Andres, Dermitzakis, Emmanouil T., Gibson, Greg, Spector, Timothy D., Thiery, Joachim, Scholz, Markus, Montgomery, Grant W., Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017). Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood. Nature Communications, 8 (483) 483, 483. doi: 10.1038/s41467-017-00473-z
2017
Journal Article
Concepts, estimation and interpretation of SNP-based heritability
Yang, Jian, Zeng, Jian, Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2017). Concepts, estimation and interpretation of SNP-based heritability. Nature Genetics, 49 (9), 1304-1310. doi: 10.1038/ng.3941
2017
Journal Article
Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method
Chen, Guo-Bo, Lee, Sang Hong, Montgomery, Grant W., Wray, Naomi R., Visscher, Peter M., Gearry, Richard B., Lawrance, Ian C., Andrews, Jane M., Bampton, Peter, Mahy, Gillian, Bell, Sally, Walsh, Alissa, Connor, Susan, Sparrow, Miles, Bowdler, Lisa M., Simms, Lisa A., Krishnaprasad, Krupa, Radford-Smith, Graham L. and Moser, Gerhard (2017). Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method. BMC Medical Genetics, 18 (1) 94, 94. doi: 10.1186/s12881-017-0451-2
Funding
Current funding
Supervision
Availability
- Professor Peter Visscher is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Statistical methods and application to analyses genome and trait data from large biobanks
Principal Advisor
Other advisors: Dr Kathryn Kemper, Professor Loic Yengo
-
Doctor Philosophy
Genetic architecture and evolution of complex traits across populations in humans
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng
-
Doctor Philosophy
Integrating GWAS and molecular QTL data to dissect genetic architecture and improve polygenic prediction
Associate Advisor
Other advisors: Dr Jian Zeng
Completed supervision
-
2022
Doctor Philosophy
Using whole-genome sequence data to elucidate complex trait variation
Principal Advisor
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Principal Advisor
Other advisors: Dr Allan McRae
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Principal Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Associate Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Genomic signature of non-random mating in human complex traits
Associate Advisor
Other advisors: Professor Loic Yengo
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Associate Advisor
Other advisors: Dr Allan McRae
-
2022
Doctor Philosophy
Genetic analyses of complex traits using biobank data
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Within and Across Populations Complex Traits and Diseases Prediction Using Summary Statistics from Large-scale Genome-wide Association Studies
Associate Advisor
Other advisors: Professor Loic Yengo
-
2020
Doctor Philosophy
Genetic Differentiation of Human Complex Traits across Worldwide Populations
Associate Advisor
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Allan McRae
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Associate Advisor
Other advisors: Dr Allan McRae
-
2019
Doctor Philosophy
Systems Genomics of Parkinson's Disease
Associate Advisor
Other advisors: Honorary Professor Jake Gratten
-
2017
Doctor Philosophy
The Genetic Architecture of Psychiatric Disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2017
Doctor Philosophy
Characterization of the genetic and environmental factors driving gene expression variability
Associate Advisor
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