
Overview
Background
Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.
Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.
Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.
Availability
- Professor Peter Visscher is:
- Not available for supervision
Fields of research
Qualifications
- Masters (Coursework) of Science, University of Edinburgh
- Doctor of Philosophy, University of Edinburgh
Research impacts
Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.
Works
Search Professor Peter Visscher’s works on UQ eSpace
2018
Other Outputs
Epigenetic prediction of complex traits and death
McCartney, Daniel L, Stevenson, Anna J, Ritchie, Stuart J, Walker, Rosie M, Zhang, Qian, Morris, Stewart W, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Gale, Catharine R, Porteous, David J, Haley, Chris S, McRae, Allan F, Wray, Naomi R, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic prediction of complex traits and death. doi: 10.1101/294116
2018
Journal Article
Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)
Hebert, Harry L., Shepherd, Bridget, Milburn, Keith, Veluchamy, Abirami, Meng, Weihua, Carr, Fiona, Donnelly, Louise A., Tavendale, Roger, Leese, Graham, Colhoun, Helen M., Dow, Ellie, Morris, Andrew D., Doney, Alexander S., Lang, Chim C., Pearson, Ewan R., Smith, Blair H. and Palmer, Colin N. A. (2018). Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS). International Journal of Epidemiology, 47 (2), 380-+. doi: 10.1093/ije/dyx140
2018
Journal Article
Narrow-sense heritability estimation of complex traits using identity-by-descent information
Evans, Luke M., Tahmasbi, Rasool, Jones, Matt, Vrieze, Scott I., Abecasis, Gonçalo R., Das, Sayantan, Bjelland, Douglas W., de Candia, Teresa R., Yang, Jian, Goddard, Michael E., Visscher, Peter M., Keller, Matthew C. and Haplotype Reference Consortium (2018). Narrow-sense heritability estimation of complex traits using identity-by-descent information. Heredity, 121 (6), 1-15. doi: 10.1038/s41437-018-0067-0
2018
Journal Article
A multi-trait Bayesian method for mapping QTL and genomic prediction
Kemper, Kathryn E., Bowman, Philip J., Hayes, Benjamin J., Visscher, Peter M. and Goddard, Michael E. (2018). A multi-trait Bayesian method for mapping QTL and genomic prediction. Genetics Selection Evolution, 50 (1) 10, 10. doi: 10.1186/s12711-018-0377-y
2018
Journal Article
Improving genetic prediction by leveraging genetic correlations among human diseases and traits
Maier, Robert M, Zhu, Zhihong, Lee, Sang Hong, Trzaskowski, Maciej, Ruderfer, Douglas M, Stahl, Eli A, Ripke, Stephan, Wray, Naomi R, Yang, Jian, Visscher, Peter M and Robinson, Matthew R (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications, 9 (1) 989, 989. doi: 10.1038/s41467-017-02769-6
2018
Journal Article
Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits
Wu, Yang, Zeng, Jian, Zhang, Futao, Zhu, Zhihong, Qi, Ting, Zheng, Zhili, Lloyd-Jones, Luke R., Marioni, Riccardo E., Martin, Nicholas G., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. Nature Communications, 9 (918) 918, 918. doi: 10.1038/s41467-018-03371-0
2018
Journal Article
Reply to Kardos et al.: estimation of inbreeding depression from SNP data
Yengo, Loic, Zhu, Zhihong, Wray, Naomi R., Weir, Bruce S., Yang, Jian, Robinson, Matthew R. and Visscher, Peter M. (2018). Reply to Kardos et al.: estimation of inbreeding depression from SNP data. Proceedings of the National Academy of Sciences, 115 (11), E2494-E2495. doi: 10.1073/pnas.1718598115
2018
Journal Article
Transformation of summary statistics from linear mixed model association on all-or-none traits to odds ratio
Lloyd-Jones, Luke R., Robinson, Matthew R., Yang, Jian and Visscher, Peter M. (2018). Transformation of summary statistics from linear mixed model association on all-or-none traits to odds ratio. Genetics, 208 (4), 1397-1408. doi: 10.1534/genetics.117.300360
2018
Journal Article
Seasonal Variability of Mineral Formation in Microbial Mats Subjected to Drying and Wetting Cycles in Alkaline and Hypersaline Sedimentary Environments
Cabestrero, O., Sanz-Montero, M. E., Arregui, L., Serrano, S. and Visscher, P. T. (2018). Seasonal Variability of Mineral Formation in Microbial Mats Subjected to Drying and Wetting Cycles in Alkaline and Hypersaline Sedimentary Environments. Aquatic Geochemistry, 24 (1), 79-105. doi: 10.1007/s10498-018-9333-2
2018
Journal Article
GWAS of epigenetic aging rates in blood reveals a critical role for TERT
Lu, Ake T., Xue, Luting, Salfati, Elias L., Chen, Brian H., Ferrucci, Luigi, Levy, Daniel, Joehanes, Roby, Murabito, Joanne M., Kiel, Douglas P., Tsai, Pei-Chien, Yet, Idil, Bell, Jordana T., Mangino, Massimo, Tanaka, Toshiko, McRae, Allan F., Marioni, Riccardo E., Visscher, Peter M., Wray, Naomi R., Deary, Ian J., Levine, Morgan E., Quach, Austin, Assimes, Themistocles, Tsao, Philip S., Absher, Devin, Stewart, James D., Li, Yun, Reiner, Alex P., Hou, Lifang, Baccarelli, Andrea A. ... Horvath, Steve (2018). GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications, 9 (1) 387, 387. doi: 10.1038/s41467-017-02697-5
2018
Journal Article
Causal associations between risk factors and common diseases inferred from GWAS summary data
Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J, Visscher, Peter M, Wray, Naomi R and Yang, Jian (2018). Causal associations between risk factors and common diseases inferred from GWAS summary data. Nature Communications, 9 (1) 224, 224. doi: 10.1038/s41467-017-02317-2
2018
Other Outputs
GWAS on family history of Alzheimer’s disease
Marioni, Riccardo E., Harris, Sarah E., McRae, Allan F., Zhang, Qian, Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine, Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer’s disease. doi: 10.1101/246223
2018
Journal Article
Evidence of directional and stabilizing selection in contemporary humans
Sanjak, Jaleal S., Sidorenko, Julia, Robinson, Matthew R., Thornton, Kevin R. and Visscher, Peter M. (2018). Evidence of directional and stabilizing selection in contemporary humans. Proceedings of the National Academy of Sciences of the United States of America, 115 (1), 151-156. doi: 10.1073/pnas.1707227114
2018
Journal Article
Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank
Barbu, Miruna C., Zeng, Yanni, Shen, Xueyi, Cox, Simon R., Clarke, Toni-Kim, Gibson, Jude, Adams, Mark J., Johnstone, Mandy, Haley, Chris S., Lawrie, Stephen M., Deary, Ian J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien ... Whalley, Heather C. (2018). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4 (1), 91-100. doi: 10.1016/j.bpsc.2018.07.006
2018
Conference Publication
Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology
Visscher, Peter M., Wray, Naomi R. and Yang, Jian (2018). Invited abstract: Leveraging big GWAS data to address question about selection, pleiotropy, assortative mating and epidemiology. 27th Annual Meeting of the International Genetic Epidemiology Society (IGES), San Diego, CA, United States, 14-16 October 2018. Hoboken, NJ, United States: John Wiley & Sons.
2018
Journal Article
Multi-trait analysis of genome-wide association summary statistics using MTAG
Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Magnusson, Patrik, Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M., Laibson, David, Cesarini, David, Neale, Benjamin M., Benjamin, Daniel J., 23andMe Research Team and Social Science Genetic Association Consortium (2018). Multi-trait analysis of genome-wide association summary statistics using MTAG. Nature Genetics, 50 (229+), 229-237. doi: 10.1038/s41588-017-0009-4
2018
Journal Article
Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels
Lupton, Michelle K., Medland, Sarah E., Gordon, Scott D., Goncalves, Tabatha, MacGregor, Stuart, Mackey, David A., Young, Terri L., Duffy, David L., Visscher, Peter M., Wray, Naomi R., Nyholt, Dale R., Bain, Lisa, Ferreira, Manuel A., Henders, Anjali K., Wallace, Leanne, Montgomery, Grant W., Wright, Margaret J. and Martin, Nicholas G. (2018). Accuracy of inferred APOE genotypes for a range of genotyping arrays and imputation reference panels. Journal of Alzheimer's Disease, 64 (1), 49-54. doi: 10.3233/JAD-171104
2018
Conference Publication
Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia
Tucci, Serena, McCoy, Rajiv, Vernot, Benjamin, Vohr, Sam, Robinson, Matthew R., Barbieri, Chiara, Fu, Wenqing, Sudoyo, Herawati, Visscher, Peter M., Barbujani, Guido, Akey, Joshua M. and Green, Richard E. (2018). Evolutionary history and adaptation from high-coverage whole-genome sequences of the pygmy population of Flores, Indonesia. 87th Annual Meeting of the American-Association-of-Physical-Anthropologists (AAPA), Austin, TX, United States, 11-14 April 2018. Hoboken, NJ, United States: John Wiley & Sons.
2018
Conference Publication
Signatures of negative selection in the genetic architecture of human complex traits
Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, Mcrae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. 48th Annual Meeting of the Behavior-Genetics-Association (BGA), Boston MA, United States, 20-23 June 2018. New York, NY United States: Springer New York.
2018
Conference Publication
Fine-mapping reveals complex genetic architecture underlying DNA methylation
Chundru, V. Kartik, Marioni, Riccardo E., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2018). Fine-mapping reveals complex genetic architecture underlying DNA methylation. Human Genome Meeting, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications. doi: 10.1186/s40246-018-0138-6
Supervision
Availability
- Professor Peter Visscher is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Statistical methods and application to analyses genome and trait data from large biobanks
Principal Advisor
Other advisors: Dr Kathryn Kemper, Professor Loic Yengo
-
Doctor Philosophy
Genetic architecture and evolution of complex traits across populations in humans
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng
Completed supervision
-
2022
Doctor Philosophy
Using whole-genome sequence data to elucidate complex trait variation
Principal Advisor
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Principal Advisor
Other advisors: Dr Allan McRae
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Principal Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Associate Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Genomic signature of non-random mating in human complex traits
Associate Advisor
Other advisors: Professor Loic Yengo
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Associate Advisor
Other advisors: Dr Allan McRae
-
2022
Doctor Philosophy
Genetic analyses of complex traits using biobank data
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Within and Across Populations Complex Traits and Diseases Prediction Using Summary Statistics from Large-scale Genome-wide Association Studies
Associate Advisor
Other advisors: Professor Loic Yengo
-
2020
Doctor Philosophy
Genetic Differentiation of Human Complex Traits across Worldwide Populations
Associate Advisor
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Allan McRae
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Associate Advisor
Other advisors: Dr Allan McRae
-
2019
Doctor Philosophy
Systems Genomics of Parkinson's Disease
Associate Advisor
Other advisors: Honorary Professor Jake Gratten
-
2017
Doctor Philosophy
The Genetic Architecture of Psychiatric Disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2017
Doctor Philosophy
Characterization of the genetic and environmental factors driving gene expression variability
Associate Advisor
Media
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