
Overview
Background
Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.
Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.
Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.
Availability
- Professor Peter Visscher is:
- Not available for supervision
Fields of research
Qualifications
- Masters (Coursework) of Science, University of Edinburgh
- Doctor of Philosophy, University of Edinburgh
Research impacts
Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.
Works
Search Professor Peter Visscher’s works on UQ eSpace
2018
Conference Publication
The genetic liability for insomnia is associated with the number of awakenings during sleep in young and healthy individuals
Ghaemmaghami, P., Muto, V., Jaspar, M., Meyer, C., Elansary, M., Van Egroo, M., Berthomier, C., Lambot, E., Brandewinder, M., Luxen, A., Degueldre, C., Salmon, E., Archer, S., Phillips, C., Dijk, D. -J., Visscher, P., Posthuma, D., Van Someren, E., Collette, F., Georges, M., Maquet, P. and Vandewalle, G. (2018). The genetic liability for insomnia is associated with the number of awakenings during sleep in young and healthy individuals. 24th Congress of the European-Sleep-Research-Society (ESRS), Basel Switzerland, Sep 25-28, 2018. HOBOKEN: WILEY.
2018
Journal Article
Oligo-Miocene lacustrine microbial and metazoan buildups from the Limagne Basin (French Massif Central)
Roche, Adeline, Vennin, Emmanuelle, Bouton, Anthony, Olivier, Nicolas, Wattinne, Aurelia, Bundeleva, Irina, Deconinck, Jean-Francois, Virgone, Aurelien, Gaucher, Eric C. and Visscher, Pieter T. (2018). Oligo-Miocene lacustrine microbial and metazoan buildups from the Limagne Basin (French Massif Central). Palaeogeography Palaeoclimatology Palaeoecology, 504, 34-59. doi: 10.1016/j.palaeo.2018.05.001
2018
Other Outputs
Epigenetic signatures of starting and stopping smoking
McCartney, Daniel L, Stevenson, Anna J, Hillary, Robert F, Walker, Rosie M, Bermingham, Mairead L, Morris, Stewart W, Clarke, Toni-Kim, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Porteous, David J, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J and Marioni, Riccardo E (2018). Epigenetic signatures of starting and stopping smoking. doi: 10.1101/402453
2018
Journal Article
Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia
Tucci, Serena, Vohr, Samuel H., McCoy, Rajiv C., Vernot, Benjamin, Robinson, Matthew R., Barbieri, Chiara, Nelson, Brad J., Fu, Wenqing, Purnomo, Gludhug A., Sudoyo, Herawati, Eichler, Evan E., Barbujani, Guido, Visscher, Peter M., Akey, Joshua M. and Green, Richard E. (2018). Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science, 361 (6401), 511-515. doi: 10.1126/science.aar8486
2018
Journal Article
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Xue, Angli, Wu, Yang, Zhu, Zhihong, Zhang, Futao, Kemper, Kathryn E., Zheng, Zhili, Yengo, Loic, Lloyd-Jones, Luke R., Sidorenko, Julia, Wu, Yeda, eQTLGen Consortium, McRae, Allan F., Visscher, Peter M., Zeng, Jian and Yang, Jian (2018). Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications, 9 (1) 2941, 2941. doi: 10.1038/s41467-018-04951-w
2018
Journal Article
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee, James J., Wedow, Robbee, Okbay, Aysu, Kong, Edward, Maghzian, Omeed, Zacher, Meghan, Nguyen-Viet, Tuan Anh, Bowers, Peter, Sidorenko, Julia, Karlsson Linnér, Richard, Fontana, Mark Alan, Kundu, Tushar, Lee, Chanwook, Li, Hui, Li, Ruoxi, Royer, Rebecca, Timshel, Pascal N., Walters, Raymond K., Willoughby, Emily A., Yengo, Loïc, 23andMe Research Team, COGENT (Cognitive Genomics Consortium), Social Science Genetic Association Consortium, Alver, Maris, Bao, Yanchun, Clark, David W., Day, Felix R., Furlotte, Nicholas A., Joshi, Peter K. ... Cesarini, David (2018). Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics, 50 (8), 1112-1121. doi: 10.1038/s41588-018-0147-3
2018
Journal Article
Formation of stromatolite lamina at the interface of oxygenic-anoxygenic photosynthesis
Pace, A., Bourillot, R., Bouton, A., Vennin, E., Braissant, O., Dupraz, C., Duteil, T., Bundeleva, I., Patrier, P., Galaup, S., Yokoyama, Y., Franceschi, M., Virgone, A. and Visscher, P. T. (2018). Formation of stromatolite lamina at the interface of oxygenic-anoxygenic photosynthesis. Geobiology, 16 (4), 378-398. doi: 10.1111/gbi.12281
2018
Journal Article
Misestimation of heritability and prediction accuracy of male-pattern baldness
Yap, Chloe X., Sirodenko, Julia, Marioni, Riccardo E., Yengo, Loic, Wray, Naomi R. and Visscher, Peter M. (2018). Misestimation of heritability and prediction accuracy of male-pattern baldness. Nature Communications, 9 (1) 2537, 2537. doi: 10.1038/s41467-018-04807-3
2018
Journal Article
A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
LeBlanc, Marissa, Zuber, Verena, Thompson, Wesley K., Andreassen, Ole A., Frigessi, Arnoldo, Andreassen, Bettina Kulle, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T. R., Farh, Kai-How, Lee, Phil, Bulik-Sullivan, Brendan, Collier, David, Huang, Hailiang, Pers, Tune, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W., Bruggeman, Richard ... Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework. BMC Genomics, 19 (1) 494. doi: 10.1186/s12864-018-4859-7
2018
Journal Article
Distribution, redox state and (bio)geochemical implications of arsenic in present day microbialites of Laguna Brava, Salar de Atacama
Sancho-Tomas, Maria, Somogyi, Andrea, Medjoubi, Kadda, Bergamaschi, Antoine, Visscher, Pieter T., Van Driessche, Alexander E. S., Gerard, Emmanuelle, Farias, Maria E., Contreras, Manuel and Philippot, Pascal (2018). Distribution, redox state and (bio)geochemical implications of arsenic in present day microbialites of Laguna Brava, Salar de Atacama. Chemical Geology, 490, 13-21. doi: 10.1016/j.chemgeo.2018.04.029
2018
Journal Article
Common disease is more complex than implied by the core gene omnigenic model
Wray, Naomi R., Wijmenga, Cisca, Sullivan, Patrick F., Yang, Jian and Visscher, Peter M. (2018). Common disease is more complex than implied by the core gene omnigenic model. Cell, 173 (7), 1573-1580. doi: 10.1016/j.cell.2018.05.051
2018
Journal Article
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A., Pavlides, Jennifer M. Whitehead, Mullins, Niamh, Charney, Alexander W., Ori, Anil P.S., Loohuis, Loes M. Olde, Domenici, Enrico, Di Florio, Arianna, Papiol, Sergi, Kalman, Janos L., Trubetskoy, Vassily, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Akil, Huda, Albani, Diego, Albus, Margot, Alda, Martin, Alexander, Madeline, Alliey-Rodriguez, Ney, Als, Thomas D., Amin, Farooq, Anjorin, Adebayo, Arranz, Maria J., Awasthi, Swapnil ... Kendler, Kenneth S. (2018). Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell, 173 (7), 1705-1715.e16. doi: 10.1016/j.cell.2018.05.046
2018
Journal Article
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, eQTLGen Consortium, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications, 9 (1) 2282, 2282. doi: 10.1038/s41467-018-04558-1
2018
Journal Article
Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans
Cuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M., Gaunt, Tom R., McRae, Allan, Visscher, Peter M., Montgomery, Grant W., Martin, Nicholas G., Hemani, Gibran, Suderman, Matthew, Relton, Caroline L., Davey Smith, George and Evans, David M. (2018). Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. Human Molecular Genetics, 27 (16), 2927-2939. doi: 10.1093/hmg/ddy206
2018
Journal Article
GWAS on family history of Alzheimer's disease
Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer's disease. Translational Psychiatry, 8 (1) 99, 99. doi: 10.1038/s41398-018-0150-6
2018
Journal Article
Erratum: evidence of directional and stabilizing selection in contemporary humans (Proceedings of the National Academy of Sciences of the United States of America (2017) 115 (151–156) DOI: 10.1073/pnas.1707227114)
Sanjak, Jaleal S., Sidorenko, Julia, Robinson, Matthew R., Thornton, Kevin R. and Visscher, Peter M. (2018). Erratum: evidence of directional and stabilizing selection in contemporary humans (Proceedings of the National Academy of Sciences of the United States of America (2017) 115 (151–156) DOI: 10.1073/pnas.1707227114). Proceedings of the National Academy of Sciences of the United States of America, 115 (20). doi: 10.1073/pnas.1806837115
2018
Journal Article
Global genetic differentiation of complex traits shaped by natural selection in humans
Guo, Jing, Wu, Yang, Zhu, Zhihong, Zheng, Zhili, Trzaskowski, Maciej, Zeng, Jian, Robinson, Matthew R., Visscher, Peter M. and Yang, Jian (2018). Global genetic differentiation of complex traits shaped by natural selection in humans. Nature Communications, 9 (1) 1865, 1865. doi: 10.1038/s41467-018-04191-y
2018
Journal Article
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till M. F., Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bryois, Julien, Buttenschon, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Coleman, Jonathan I. R., Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Crowley, Cheynna A. ... Sullivan, Patrick F. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50 (5), 668-+. doi: 10.1038/s41588-018-0090-3
2018
Journal Article
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
Evans, Luke M., Tahmasbi, Rasool, Vrieze, Scott I., Abecasis, Gonçalo R., Das, Sayantan, Gazal, Steven, Bjelland, Douglas W., de Candia, Teresa R., Haplotype Reference Consortium, Goddard, Michael E., Neale, Benjamin M., Yang, Jian, Visscher, Peter M. and Keller, Matthew C. (2018). Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits. Nature genetics, 50 (5), 737-745. doi: 10.1038/s41588-018-0108-x
2018
Journal Article
Signatures of negative selection in the genetic architecture of human complex traits
Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, McRae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. Nature Genetics, 50 (5), 746-753. doi: 10.1038/s41588-018-0101-4
Supervision
Availability
- Professor Peter Visscher is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Statistical methods and application to analyses genome and trait data from large biobanks
Principal Advisor
Other advisors: Dr Kathryn Kemper, Professor Loic Yengo
-
Doctor Philosophy
Genetic architecture and evolution of complex traits across populations in humans
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng
Completed supervision
-
2022
Doctor Philosophy
Using whole-genome sequence data to elucidate complex trait variation
Principal Advisor
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Principal Advisor
Other advisors: Dr Allan McRae
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Principal Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Associate Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Genomic signature of non-random mating in human complex traits
Associate Advisor
Other advisors: Professor Loic Yengo
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Associate Advisor
Other advisors: Dr Allan McRae
-
2022
Doctor Philosophy
Genetic analyses of complex traits using biobank data
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Within and Across Populations Complex Traits and Diseases Prediction Using Summary Statistics from Large-scale Genome-wide Association Studies
Associate Advisor
Other advisors: Professor Loic Yengo
-
2020
Doctor Philosophy
Genetic Differentiation of Human Complex Traits across Worldwide Populations
Associate Advisor
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Allan McRae
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Associate Advisor
Other advisors: Dr Allan McRae
-
2019
Doctor Philosophy
Systems Genomics of Parkinson's Disease
Associate Advisor
Other advisors: Honorary Professor Jake Gratten
-
2017
Doctor Philosophy
The Genetic Architecture of Psychiatric Disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2017
Doctor Philosophy
Characterization of the genetic and environmental factors driving gene expression variability
Associate Advisor
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