Overview
Background
Associate Professor Ingrid Winkler is a Senior Research Fellow and head of the Stem Cells and Cancer group at Mater Research Institute - the University of Queensland, Brisbane, Australia.
A/Prof Winkler’s research focuse is understanding how micro-environments in the body protect and control normal and/or malignant stem Cells. Her innovative stem cell niche research has been recognised as among ten of the best research projects in Australia (by National Health and Medical Research Council) with patents and clinical translation.
A/Prof Winker's current research explores how stem cell niches change with ageing, inflammation, cancer therapy or radiation damage, with view to identify key detrimental niche components involved. This knowledge may be used to develop novel treatment strategies to improve cancer therapy outcomes, alleviate adverse cancer therapy side-effects that currently affect up tp 80% of Australian cancer therapy patientts plus facilitate healthier old age.
Availability
- Dr Ingrid Winkler is:
- Available for supervision
Research impacts
A/Prof's research on how normal and malignant cells alter their local environment (niches) was at the forefront of this new field. The identification of mechanisms by which normal and malignant cells change their niche, enabled these components to be therapeutically targeted leading to high impact manuscripts, industry partnerships and clinical translation with large Phase 2/3 clinical trials ongoing.
Works
Search Professor Ingrid Winkler’s works on UQ eSpace
1997
Journal Article
Characterization of the genome of feline foamy virus and its proteins shows distinct features different from those of primate spumaviruses
Winkler, , Bodem, J, Haas, L, Zemba, M, Delius, H, Flower, R, Flugel, RM and Lochelt, M (1997). Characterization of the genome of feline foamy virus and its proteins shows distinct features different from those of primate spumaviruses. Journal of Virology, 71 (9), 6727-6741. doi: 10.1128/JVI.71.9.6727-6741.1997
1997
Journal Article
A rapid streptavidin-capture ELISA specific for the detection of antibodies to feline foamy virus
Winkler, IG, Lochelt, M, Levesque, JP, Bodem, J, Flugel, RM and Flower, RLP (1997). A rapid streptavidin-capture ELISA specific for the detection of antibodies to feline foamy virus. Journal of Immunological Methods, 207 (1), 69-77. doi: 10.1016/S0022-1759(97)00109-9
1996
Journal Article
Characterization of the spliced pol transcript of feline foamy virus: The splice acceptor site of the pol transcript is located in gag of foamy viruses
Bodem, J, Lochelt, M, Winkler, , Flower, RP, Delius, H and Flugel, RM (1996). Characterization of the spliced pol transcript of feline foamy virus: The splice acceptor site of the pol transcript is located in gag of foamy viruses. Journal of Virology, 70 (12), 9024-9027. doi: 10.1128/JVI.70.12.9024-9027.1996
1976
Journal Article
FAILURE OF GLOBIN MESSENGER-RNA TO STIMULATE GLOBIN-SYNTHESIS IN CELL-FREE-EXTRACTS OF INTERFERON-TREATED GLOBIN-SYNTHESIZING MOUSE ERYTHROLEUKEMIC CELLS
HILLER, G, WINKLER, , VIEHHAUSER, G, JUNGWIRTH, C, BODO, G, DUBE, S and OSTERTAG, W (1976). FAILURE OF GLOBIN MESSENGER-RNA TO STIMULATE GLOBIN-SYNTHESIS IN CELL-FREE-EXTRACTS OF INTERFERON-TREATED GLOBIN-SYNTHESIZING MOUSE ERYTHROLEUKEMIC CELLS. Virology, 69 (1), 360-363. doi: 10.1016/0042-6822(76)90228-2
Funding
Supervision
Availability
- Dr Ingrid Winkler is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Reducing the long-term side effects of chemotherapy in cancer survivors
Associate Advisor
Other advisors: Dr Hana Starobova, Professor Irina Vetter
-
Doctor Philosophy
Delineating the role of E-selectin in vincristine-induced peripheral neuropathy
Associate Advisor
Other advisors: Dr Hana Starobova, Professor Irina Vetter
Completed supervision
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2024
Doctor Philosophy
Immune cell regulation by the microenvironment
Principal Advisor
Other advisors: Honorary Professor Kristen Radford, Dr Hana Starobova
-
-
2019
Doctor Philosophy
The role of bone marrow niches in the regulation of normal and malignant haematopoietic stem cells
Principal Advisor
Other advisors: Professor Jean-Pierre Levesque
-
2017
Doctor Philosophy
The role of prostaglandin I2 in haematopoietic stem cell in the bone marrow niche
Principal Advisor
Other advisors: Professor Jean-Pierre Levesque
-
2015
Doctor Philosophy
Understanding heterotopic ossification after spinal cord injury
Principal Advisor
Other advisors: Professor Jean-Pierre Levesque
-
2023
Doctor Philosophy
Unravelling the response and functional role of microglia in different inflammatory conditions
Associate Advisor
Other advisors: Professor Marc Ruitenberg, Professor Jana Vukovic
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2022
Doctor Philosophy
Establishing Humanized Mouse Models to Evaluate Immunotherapy
Associate Advisor
Other advisors: Honorary Professor Kristen Radford
-
2021
Doctor Philosophy
The Role of Macrophages in Acute Myeloid Leukaemia Progression and Sensitivity to Chemotherapy
Associate Advisor
Other advisors: Professor Jean-Pierre Levesque
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2015
Doctor Philosophy
Role of Bone Marrow Macrophages in Regulating Haematopoiesis
Associate Advisor
Other advisors: Professor Jean-Pierre Levesque
-
2011
Doctor Philosophy
The Role of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in Haematopoiesis
Associate Advisor
Other advisors: Professor Jean-Pierre Levesque
Media
Enquiries
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