Professor Geoffrey McLachlan
Professor

Geoffrey McLachlan

Email: 
Phone: 
+61 7 336 52150

Background

Professor Geoffrey McLachlan's research interests are in: data mining, statistical analysis of microarray, gene expression data, finite mixture models and medical statistics.

Professor McLachlan received his PhD from the University of Queensland in 1974 and his DSc from there in 1994. His current research projects in statistics are in the related fields of classification, cluster and discriminant analyses, image analysis, machine learning, neural networks, and pattern recognition, and in the field of statistical inference. The focus in the latter field has been on the theory and applications of finite mixture models and on estimation via the EM algorithm.

A common theme of his research in these fields has been statistical computation, with particular attention being given to the computational aspects of the statistical methodology. This computational theme extends to Professor McLachlan's more recent interests in the field of data mining.

He is also actively involved in research in the field of medical statistics and, more recently, in the statistical analysis of microarray gene expression data.

Availability

Professor Geoffrey McLachlan is:
Available for supervision
Media expert

Fields of research

Statistics

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland
  • Doctoral Diploma of Science (Advanced), The University of Queensland
  • Australian Mathematical Society, Australian Mathematical Society

Search Professor Geoffrey McLachlan’s works on UQ eSpace

370 works between 1972 and 2024
All (370) Journal Article (249) Book Chapter (34) Conference Publication (75) Book (9) Other Outputs (2) Edited Outputs (1)

181 - 200 of 370 works

2008

Journal Article

Professor Gopal Kanji's retirement as editor of Journal of Applied Statistics

Agrawal, M. C., Caudill, Steven B., Chakraborti, S., Draper, Norman, Dryden, Ian, Gani, Joe, Gilmour, Steven G., Govindarajulu, Z., Hand, David J., Franses, Philip Hans, Kacker, Raghu, Khamis, Harry, Khuri, Andre I., Lewis, Toby, Mardia, Kanti, McLachlan, Geoff, Naik, Dayanand, Prescott, Phil, Kumar, V. S. Sampath, Tomizawa, Sadao and Wynn, Henry (2008). Professor Gopal Kanji's retirement as editor of Journal of Applied Statistics. Journal of Applied Statistics, 35 (1), 1-8. doi: 10.1080/02664760701814495

Professor Gopal Kanji's retirement as editor of Journal of Applied Statistics

2008

Book

The EM algorithm and extensions

McLachlan, Geoffrey J. and Krishnan, Thriyambakam (2008). The EM algorithm and extensions. 2nd ed. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9780470191613

The EM algorithm and extensions

2008

Book Chapter

Correcting for Selection Bias via Cross-Validation in the Classification of Microarray Data

McLachlan, G J., Chevelu, J. and Zhu, J. (2008). Correcting for Selection Bias via Cross-Validation in the Classification of Microarray Data. Beyond Parametrics in Interdisciplinary Research: Festschrift in Honor of Professor Pranab K. Sen. (pp. 364-376) edited by Balakrishnan, N., Pena, E. A. and Silvapulle, M. J.. United States: Institute of Mathematical Statistics. doi: 10.1214/193940307000000284

Correcting for Selection Bias via Cross-Validation in the Classification of Microarray Data

2008

Conference Publication

Clustering via mixture regression models with random effects

McLachlan, G. J., Ng, S. K. and Wang, K. (2008). Clustering via mixture regression models with random effects. 18th Symposium on Computational Statistics (COMSTAT 2008), Porto, Portugal, 24-29 August 2008. Heidelberg, Germany: Physica-Verlag,. doi: 10.1007/978-3-7908-2084-3_33

Clustering via mixture regression models with random effects

2008

Book Chapter

Clustering

McLachlan, G. J., Bean, R. W. and Ng, S.-K. (2008). Clustering. Bioinformatics, volume 2: Structure, function and applications. (pp. 423-439) edited by J. M. Keith. New Jersey, United States: Humana Press. doi: 10.1007/978-1-60327-429-6_22

Clustering

2008

Journal Article

Large-scale simultaneous inference with applications to the detection of differential expression with microarray data (with discussion)

McLachlan, Geoff J., Wang, Kent and Ng, Shu Kay (2008). Large-scale simultaneous inference with applications to the detection of differential expression with microarray data (with discussion). Statistica, 68 (1), 1-30. doi: 10.6092/issn.1973-2201/3525

Large-scale simultaneous inference with applications to the detection of differential expression with microarray data (with discussion)

2008

Journal Article

Top 10 Algorithms in Data Mining

Wu, X., Kumar, V., Quinlan, J. R., Ghosh, J., Yang, Q., Motoda, H., McLachlan, G. J., Ng, A., Liu, B., Yu, P. S., Zhou, Z. H., Steinbach, M., Hand, D. J. and Steinberg, D. (2008). Top 10 Algorithms in Data Mining. Knowledge and Information Systems, 14 (1), 1-37. doi: 10.1007/s10115-007-0114-2

Top 10 Algorithms in Data Mining

2007

Journal Article

Two-component Poisson Mixture Regression Modelling of Count Data With Bivariate Random Effects

Wang, Kui, Yau, Kelvin K. W., Lee, Andy H. and McLachlan, Geoffrey J. (2007). Two-component Poisson Mixture Regression Modelling of Count Data With Bivariate Random Effects. Mathematical and Computer Modelling, 46 (11-12), 1468-1476. doi: 10.1016/j.mcm.2007.02.003

Two-component Poisson Mixture Regression Modelling of Count Data With Bivariate Random Effects

2007

Journal Article

Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling

Lenzenweger, M. F., McLachlan, G. J. and Rubin, D. B. (2007). Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling. Journal of Abnormal Psychology, 116 (1), 16-29. doi: 10.1037/0021-843X.116.1.16

Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling

2007

Journal Article

A Score Test for Overdispersion in Zero-Inflated Poisson Mixed Regression Model

Xiang, L., Lee, A. H., Yau, K. K. W. and McLachlan, G. J. (2007). A Score Test for Overdispersion in Zero-Inflated Poisson Mixed Regression Model. Statistics in Medicine, 26 (7), 1608-1622. doi: 10.1002/sim.2616

A Score Test for Overdispersion in Zero-Inflated Poisson Mixed Regression Model

2007

Journal Article

Extension of Mixture-of-Experts Networks for Binary Classification of Hierarchical Data

Ng, S. K. and McLachlan, G. J. (2007). Extension of Mixture-of-Experts Networks for Binary Classification of Hierarchical Data. Artificial Intelligence in Medicine, 41 (1), 57-67. doi: 10.1016/j.artmed.2007.06.001

Extension of Mixture-of-Experts Networks for Binary Classification of Hierarchical Data

2007

Journal Article

Application of gene shaving and mixture models to cluster microarray gene expression data

Do, K. A., McLachlan, G. J., Bean, R. W. and Wen, S. (2007). Application of gene shaving and mixture models to cluster microarray gene expression data. Cancer Informatics, 5, 25-43. doi: 10.1177/117693510700500002

Application of gene shaving and mixture models to cluster microarray gene expression data

2007

Conference Publication

Resolving the latent structure of schizophrenia endophenotypes using em-based finite mixture modeling

Lenzenweger, M. F., McLachlan, G. and Rubin, D. B. (2007). Resolving the latent structure of schizophrenia endophenotypes using em-based finite mixture modeling. 10th International Congress on Schizophrenia Research, Savannah Ga, 02-06 April 2005. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/schbul/sbm004

Resolving the latent structure of schizophrenia endophenotypes using em-based finite mixture modeling

2007

Journal Article

Maternity length of stay modelling by Gamma mixture regression with random effects

Lee, Andy H., Wang, Kui, Yau, Kelvin K. W., McLachlan, Geoffrey J. and Ng, Shu Kay (2007). Maternity length of stay modelling by Gamma mixture regression with random effects. Biometrical Journal, 49 (5), 750-764. doi: 10.1002/bimj.200610371

Maternity length of stay modelling by Gamma mixture regression with random effects

2007

Journal Article

Segmentation and intensity estimation of microarray images using a gamma-t mixture model

Baek, J., Son, Y. S. and McLachlan, G. J. (2007). Segmentation and intensity estimation of microarray images using a gamma-t mixture model. Bioinformatics, 23 (4), 458-465. doi: 10.1093/bioinformatics/btl630

Segmentation and intensity estimation of microarray images using a gamma-t mixture model

2007

Journal Article

Multilevel Survival Modelling of Recurrent Urinary Tract Infections

Wang, Kui, Yau, Kelvin K. W., Lee, Andy H. and McLachlan, Geoffrey J. (2007). Multilevel Survival Modelling of Recurrent Urinary Tract Infections. Computer Methods and Programs in Biomedicine, 87 (3), 225-229. doi: 10.1016/j.cmpb.2007.05.013

Multilevel Survival Modelling of Recurrent Urinary Tract Infections

2007

Journal Article

Extension of the Mixture of Factor Analyzers Model to Incorporate the Multivariate t-Distribution

McLachlan, G. J., Bean, R. W. and Jones, L. B. T. (2007). Extension of the Mixture of Factor Analyzers Model to Incorporate the Multivariate t-Distribution. Computational Statistics & Data Analysis, 51 (11), 5327-5338. doi: 10.1016/j.csda.2006.09.015

Extension of the Mixture of Factor Analyzers Model to Incorporate the Multivariate t-Distribution

2007

Journal Article

A tutorial in genetic epidemiology and some considerations in statistical modeling

Suarez, E., Sariol, C. A., Burguete, A. and McLachlan, G. J. (2007). A tutorial in genetic epidemiology and some considerations in statistical modeling. Puerto Rico Health Sciences Journal, 26 (4), 401-421.

A tutorial in genetic epidemiology and some considerations in statistical modeling

2007

Conference Publication

Merging algorithm to reduce dimensionality in application to web-mining

Nikulin, V and McLachlan, GJ (2007). Merging algorithm to reduce dimensionality in application to web-mining. 20th Australian Joint Conference on Artificial Intelligence, Gold Coast, Qld, Australia, 2-6 December, 2007. Berlin, Germany: Springer Berlin / Heidelberg. doi: 10.1007/978-3-540-76928-6_88

Merging algorithm to reduce dimensionality in application to web-mining

2007

Conference Publication

Subpopulations with iron deficiency, liver disease, or HFE mutations revealed by statistical mixture modeling of transferrin saturation and serum ferritin concentration in Asians, African American, Hispanics, and Whites

McLaren, C. E., Gordeuk, V. R., Chen, W. P., Barton, J. C., Acton, R. T., Speechley, M., Castro, O., Adams, P. C., Snively, B. M., Harris, E. L., Reboussin, D. M., McLachlan, G. J., Bean, R. and McLaren, G. D. (2007). Subpopulations with iron deficiency, liver disease, or HFE mutations revealed by statistical mixture modeling of transferrin saturation and serum ferritin concentration in Asians, African American, Hispanics, and Whites. 49th Annual Meeting of the American Society of Hematology, Atlanta, GA, U.S.A., 8 - 11 December 2007. Washington, DC, U.S.A.: American Society of Hematology.

Subpopulations with iron deficiency, liver disease, or HFE mutations revealed by statistical mixture modeling of transferrin saturation and serum ferritin concentration in Asians, African American, Hispanics, and Whites

Current funding

  • 2023 - 2026
    A Novel Approach to Semi-Supervised Statistical Machine Learning
    ARC Discovery Projects
    Open grant

Past funding

  • 2018 - 2022
    Classification methods for providing personalised and class decisions
    ARC Discovery Projects
    Open grant
  • 2017 - 2024
    ARC Training Centre for Innovation in Biomedical Imaging Technology
    ARC Industrial Transformation Training Centres
    Open grant
  • 2017 - 2020
    Power Quality Monitoring of Grids with High Penetration of Power Converters
    ARC Linkage Projects
    Open grant
  • 2017 - 2020
    Expanding the Role of Mixture Models in Statistical Analyses of Big Data
    ARC Discovery Projects
    Open grant
  • 2015 - 2018
    Gene expression profiling in critically ill patients with septic shock: The ADRENAL-GEPS Study
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    Large-Scale Statistical Inference: Multiple Testing
    ARC Discovery Projects
    Open grant
  • 2014 - 2016
    System to Synapse
    ARC Linkage Projects
    Open grant
  • 2014 - 2017
    Advanced Mixture Models for the Analysis of Modern-Day Data
    ARC Discovery Projects
    Open grant
  • 2012 - 2014
    System to synapse: a small animal imaging suite
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2012 - 2014
    Joint Clustering and Matching of Multivariate Samples Across Objects
    ARC Discovery Projects
    Open grant
  • 2012 - 2014
    Statistical Modelling of Complex, High-Dimensional Data
    Vice-Chancellor's Senior Research Fellowship
    Open grant
  • 2011 - 2013
    A New Approach to Fast Matrix Factorization for the Statistical Analysis of High-Dimensional Data
    ARC Discovery Projects
    Open grant
  • 2008 - 2010
    Mixture models for high-dimensional clustering with applications to tumour classification, network intrusion, and text classification
    ARC Discovery Projects
    Open grant
  • 2007 - 2011
    Multivariate Methods for the Analysis of Microarray Gene-Expression Data with Applications to Cancer Diagnostics
    ARC Discovery Projects
    Open grant
  • 2007 - 2009
    Noncoding RNAs as prognostic markers and therapeutic targets in breast cancer
    NHMRC Project Grant
    Open grant
  • 2004
    ARC Network in Imaging Science and Technology
    ARC Seed Funding for Research Networks
    Open grant
  • 2004
    ARC Research Network in Microarray Technology
    ARC Seed Funding for Research Networks
    Open grant
  • 2003 - 2010
    ARC Centre of Excellence in Bioinformatics
    ARC Centres of Excellence
    Open grant
  • 2003
    Classification of Microarray Gene-Expression Data
    ARC Discovery Projects
    Open grant
  • 2003
    Classification of Microarray Gene-expression Data
    UQ External Support Enabling Grant
    Open grant
  • 2003
    Unsupervised learning of finite mixture models in data mining applications
    ARC Discovery Projects
    Open grant
  • 2000 - 2002
    Classification of Multiply Observed Features in Terms of Fitted Densities
    ARC Australian Research Council (Large grants)
    Open grant
  • 2000 - 2002
    On Algorithms for the Automatic Analysis and Segmentation of Correlated Images
    ARC Australian Research Council (Large grants)
    Open grant
  • 1999 - 2001
    Artificial Neural Networks and the EM Algorithm
    ARC Australian Research Council (Large grants)
    Open grant
  • 1999
    On mixture regression models with constrained components for application to failure data on heart valves
    ARC Australian Research Council (Small grants)
    Open grant
  • 1998
    Robust cluster analysis
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997
    On mixture models in medical imaging
    ARC Australian Research Council (Small grants)
    Open grant
  • 1997 - 1999
    The Analysis of Plant Adaptation Data with Emphasis on Unbalanced Sets
    ARC Australian Research Council (Large grants)
    Open grant
  • 1995 - 1997
    Approximation of multi-dimensional functions for curve fitting and model building
    ARC Australian Research Council (Large grants)
    Open grant

Availability

Professor Geoffrey McLachlan is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

Contact Professor Geoffrey McLachlan directly for media enquiries about:

  • Bioinformatics
  • Computation - statistics
  • Computer learning
  • Data mining
  • Gene expression data
  • Image analysis - statistics
  • Machine learning
  • Neural networks
  • Pattern recognition - statistics
  • Statistical methodology
  • Statistics

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