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Professor Peter Visscher
Professor

Peter Visscher

Email: 
Phone: 
+61 7 344 37045

Overview

Background

Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.

Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.

Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.

Availability

Professor Peter Visscher is:
Not available for supervision

Fields of research

Qualifications

  • Masters (Coursework) of Science, University of Edinburgh
  • Doctor of Philosophy, University of Edinburgh

Research impacts

Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.

Works

Search Professor Peter Visscher’s works on UQ eSpace

803 works between 1987 and 2025

81 - 100 of 803 works

2021

Journal Article

Cohort profile: DOLORisk Dundee: a longitudinal study of chronic neuropathic pain

Hebert, Harry L., Veluchamy, Abirami, Baskozos, Georgios, Fardo, Francesca, Van Ryckeghem, Dimitri M. L., Pascal, Mathilde M. V., Jones, Claire, Milburn, Keith, Pearson, Ewan R., Crombez, Geert, Bennett, David L. H., Meng, Weihua, Palmer, Colin N. A. and Smith, Blair H. (2021). Cohort profile: DOLORisk Dundee: a longitudinal study of chronic neuropathic pain. BMJ Open, 11 (5) e042887, 1-11. doi: 10.1136/bmjopen-2020-042887

Cohort profile: DOLORisk Dundee: a longitudinal study of chronic neuropathic pain

2021

Journal Article

Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia

Restuadi, Restuadi, Garton, Fleur C., Benyamin, Beben, Lin, Tian, Williams, Kelly L., Vinkhuyzen, Anna, van Rheenen, Wouter, Zhu, Zhihong, Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Visscher, Peter M., Needham, Merrilee, Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Wray, Naomi R. and McRae, Allan F. (2021). Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia. European Journal of Human Genetics, 30 (5), 1-8. doi: 10.1038/s41431-021-00885-y

Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia

2021

Journal Article

Variation in VKORC1 is associated with vascular dementia

Mur, Jure, McCartney, Daniel L., Chasman, Daniel I., Visscher, Peter M., Muniz-Terrera, Graciela, Cox, Simon R., Russ, Tom C. and Marioni, Riccardo E. (2021). Variation in VKORC1 is associated with vascular dementia. Journal of Alzheimer's Disease, 80 (3), 1329-1337. doi: 10.3233/JAD-201256

Variation in VKORC1 is associated with vascular dementia

2021

Journal Article

Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

Hivert, Valentin, Sidorenko, Julia, Rohart, Florian, Goddard, Michael E., Yang, Jian, Wray, Naomi R., Yengo, Loic and Visscher, Peter M. (2021). Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals. The American Journal of Human Genetics, 108 (5), 786-798. doi: 10.1016/j.ajhg.2021.02.014

Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

2021

Journal Article

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

Nabais, Marta F., Laws, Simon M., Lin, Tian, Vallerga, Costanza L., Armstrong, Nicola J., Blair, Ian P., Kwok, John B., Mather, Karen A., Mellick, George D., Sachdev, Perminder S., Wallace, Leanne, Henders, Anjali K., Zwamborn, Ramona A. J., Hop, Paul J., Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A. Y., Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kloszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee ... McRae, Allan F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22 (1) 90, 1-30. doi: 10.1186/s13059-021-02275-5

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

2021

Journal Article

Quantifying genetic heterogeneity between continental populations for human height and body mass index

Guo, Jing, Bakshi, Andrew, Wang, Ying, Jiang, Longda, Yengo, Loic, Goddard, Michael E., Visscher, Peter M. and Yang, Jian (2021). Quantifying genetic heterogeneity between continental populations for human height and body mass index. Scientific Reports, 11 (1) 5240, 1-9. doi: 10.1038/s41598-021-84739-z

Quantifying genetic heterogeneity between continental populations for human height and body mass index

2021

Journal Article

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Wu, Yeda, Murray, Graham K., Byrne, Enda M., Sidorenko, Julia, Visscher, Peter M. and Wray, Naomi R. (2021). GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Nature Communications, 12 (1) 1146, 1-17. doi: 10.1038/s41467-021-21280-7

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

2021

Journal Article

Widespread signatures of natural selection across human complex traits and functional genomic categories

Zeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2021). Widespread signatures of natural selection across human complex traits and functional genomic categories. Nature Communications, 12 (1) 1164, 1-12. doi: 10.1038/s41467-021-21446-3

Widespread signatures of natural selection across human complex traits and functional genomic categories

2021

Journal Article

Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals

Kemper, Kathryn E., Yengo, Loic, Zheng, Zhili, Abdellaoui, Abdel, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R., Yang, Jian and Visscher, Peter M. (2021). Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals. Nature Communications, 12 (1) 1050, 1050. doi: 10.1038/s41467-021-21283-4

Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals

2021

Journal Article

Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank

Yap, Chloe X., Alvares, Gail A., Henders, Anjali K., Lin, Tian, Wallace, Leanne, Farrelly, Alaina, McLaren, Tiana, Berry, Jolene, Vinkhuyzen, Anna A. E., Trzaskowski, Maciej, Zeng, Jian, Yang, Yuanhao, Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren, Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Visscher, Peter M., Dawson, Paul A., Dissanayake, Cheryl ... Gratten, Jacob (2021). Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank. Molecular Autism, 12 (1) 12, 12. doi: 10.1186/s13229-020-00407-5

Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank

2021

Journal Article

Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes

Xue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2021). Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes. Nature Communications, 12 (1) 6450, 6450. doi: 10.1038/s41467-020-20237-6

Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes

2021

Journal Article

Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes

Xue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2021). Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes. Nature Communications, 12 (1) 988, 988. doi: 10.1038/s41467-021-21294-1

Correction: Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes

2021

Journal Article

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

2021

Journal Article

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

Mills, Melinda C., Tropf, Felix C., Brazel, David M., van Zuydam, Natalie, Vaez, Ahmad, Agbessi, Mawussé, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand Kumar, Arindrarto, Wibowo, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Jan Bonder, Marc, Boomsma, Dorret I., Christiansen, Mark W., Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Greg, Heijmans, Bastiaan T., Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette ... Human Reproductive Behaviour Consortium (2021). Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Nature Human Behaviour, 5 (12), 1717-1730. doi: 10.1038/s41562-021-01135-3

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

2021

Journal Article

From basic science to clinical application of polygenic risk scores : a primer

Wray, Naomi R., Lin, Tian, Austin, Jehannine, McGrath, John J., Hickie, Ian B., Murray, Graham K. and Visscher, Peter M. (2021). From basic science to clinical application of polygenic risk scores : a primer. JAMA Psychiatry, 78 (1), 101-109. doi: 10.1001/jamapsychiatry.2020.3049

From basic science to clinical application of polygenic risk scores : a primer

2021

Conference Publication

Association and prediction of phenotypic traits from neuroimaging data using a multi-component mixed model excluding the target vertex

Couvy-Duchesne, Baptiste, Zhang, Futao, Kemper, Kathryn E., Sidorenko, Julia, Wray, Naomi R., Visscher, Peter M., Yang, Jian and Colliot, Olivier (2021). Association and prediction of phenotypic traits from neuroimaging data using a multi-component mixed model excluding the target vertex. Conference on Medical Imaging - Image Processing, Online, 15-19 February, 2021. Bellingham, WA, United States: SPIE. doi: 10.1117/12.2581022

Association and prediction of phenotypic traits from neuroimaging data using a multi-component mixed model excluding the target vertex

2021

Journal Article

Resource profile and user guide of the Polygenic Index Repository

Becker, Joel, Burik, Casper A. P., Goldman, Grant, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Belsky, Daniel W., Karlsson Linnér, Richard, Ahlskog, Rafael, Kleinman, Aaron, Hinds, David A., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Huber, Karen E., Litterman, Nadia K., McCreight, Jennifer C., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F. ... Okbay, Aysu (2021). Resource profile and user guide of the Polygenic Index Repository. Nature Human Behaviour, 5 (12), 1744-1758. doi: 10.1038/s41562-021-01119-3

Resource profile and user guide of the Polygenic Index Repository

2020

Journal Article

Bayesian reassessment of the epigenetic architecture of complex traits

Trejo Banos, Daniel, McCartney, Daniel L., Patxot, Marion, Anchieri, Lucas, Battram, Thomas, Christiansen, Colette, Costeira, Ricardo, Walker, Rosie M., Morris, Stewart W., Campbell, Archie, Zhang, Qian, Porteous, David J., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., Haley, Chris S., Evans, Kathryn L., Deary, Ian J., McIntosh, Andrew M., Hemani, Gibran, Bell, Jordana T., Marioni, Riccardo E. and Robinson, Matthew R. (2020). Bayesian reassessment of the epigenetic architecture of complex traits. Nature Communications, 11 (1) 2865, 2865. doi: 10.1038/s41467-020-16520-1

Bayesian reassessment of the epigenetic architecture of complex traits

2020

Journal Article

Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease

Croese, John, Miller, Gregory C., Marquart, Louise, Llewellyn, Stacey, Gupta, Rohit, Becker, Luke, Clouston, Andrew D., Welch, Christine, Sidorenko, Julia, Wallace, Leanne, Visscher, Peter M., Remedios, Matthew L., McCarthy, James S., OʼRourke, Peter, Radford-Smith, Graham, Loukas, Alex, Norrie, Mark, Masson, John W., Gearry, Richard B., Rahman, Tony and Giacomin, Paul R. (2020). Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease. Clinical and Translational Gastroenterology, 11 (12) e00274, 1-11. doi: 10.14309/ctg.0000000000000274

Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease

2020

Journal Article

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Adams, Mark J., Clarke, Toni-Kim, McIntosh, Andrew M., Deary, Ian J., Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard ... McIntosh, Andrew M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications, 11 (1) 2301. doi: 10.1038/s41467-020-16022-0

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Funding

Current funding

  • 2019 - 2025
    Causes and consequence of human trait variation
    ARC Australian Laureate Fellowships
    Open grant

Past funding

  • 2022 - 2025
    Genetic architecture and evolution of complex traits across populations
    ARC Discovery Projects
    Open grant
  • 2018 - 2024
    Estimating the genetic and environmental architecture of psychiatric disorders (NIH Grant administered by the University of Colorado)
    University of Colorado
    Open grant
  • 2017 - 2023
    Complex trait genomics
    NHMRC Program Grant
    Open grant
  • 2016 - 2019
    Genetic analysis of the relationship between parental age and risk of psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    Phenotypic profiling from DNA using genetic and epigenetic information
    ARC Discovery Projects
    Open grant
  • 2016 - 2018
    The genetics of ageing in human populations
    ARC Discovery Projects
    Open grant
  • 2015 - 2019
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2015 - 2020
    Analysis of Genome-Wide Data in the Health and Retirement Study (NIH grant administered by the University of Southern California)
    University of Southern California
    Open grant
  • 2015 - 2019
    1/2 A Large-Scale Schizophrenia Association Study in Sweden (NIH grant administered by the University of North Carolina at Chapel Hill)
    University of North Carolina
    Open grant
  • 2015 - 2017
    Increasing the power of GxE detection by using multi-locus genome-wide predictors (NIH grant administered by Harvard Medical School)
    Harvard Medical School
    Open grant
  • 2015 - 2019
    NHMRC Research Fellowship: Neurogenetics and Statistical Genomics
    NHMRC Research Fellowship
    Open grant
  • 2014
    Deciphering the genetic code of diseases
    National Computational Merit Allocation Scheme
    Open grant
  • 2014
    Trans-ethnic and trans-omic statistical analyses to identify new ALS risk variants
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2013 - 2018
    Estimating the Frequencies and Population Specificities of Risk Alleles (NIH grant administered by the University of Colorado)
    University of Colorado
    Open grant
  • 2013 - 2016
    CAGE: Consortium for the Architecture of Gene Expression
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Estimation and partitioning of the still-missing heritability for complex disease
    NHMRC Project Grant
    Open grant
  • 2013 - 2016
    Estimation of non-additive genetic variance for complex traits using genome-wide SNP and sequence data
    ARC Discovery Projects
    Open grant
  • 2013 - 2016
    Exploiting SNP data in epidemiology and genetics through multivariate analysis of complex traits
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    The genetic architecture and evolution of quantitative traits (ARC Discovery Project administered by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2012 - 2018
    Statistical and Quantitative Genetics (NIH Grant administered by the University of Washington)
    University of Washington (Seattle)
    Open grant
  • 2012 - 2017
    Statistical genetic analyses of social and economic outcomes
    Stockholm School of Economics
    Open grant
  • 2012 - 2017
    Belgian Medical Genomics Initiative (BeMGI)
    University of Liege
    Open grant
  • 2012
    Explaining the Dark Matter of Genome-wide Association Studies for Complex Disease
    NHMRC Project Grant
    Open grant
  • 2011 - 2014
    Better Methods for Individual Risk Prediction of Complex Traits in Human Populations
    NHMRC Project Grant
    Open grant
  • 2011 - 2014
    NHMRC Research Fellowship (SPRF)
    NHMRC Research Fellowship
    Open grant
  • 2011 - 2017
    Theoretical Population Genetics (NIH Subcontract administered by the University of Washington)
    University of Washington (Seattle)
    Open grant
  • 2010 - 2013
    Identifying eQTLs and endophenotyping known CNVs in a large Australian schizophrenia sample
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Why is most of the genetic variance for complex traits undetected by large powerful screens of common variants? (ARC Discovery Project administered by The University of Melbourne)
    University of Melbourne
    Open grant
  • 2007 - 2009
    Maximising knowledge from dense SNP data using multi-locus analysis
    ARC Discovery Projects
    Open grant

Supervision

Availability

Professor Peter Visscher is:
Not available for supervision

Supervision history

Current supervision

  • Doctor Philosophy

    Statistical methods and application to analyses genome and trait data from large biobanks

    Principal Advisor

    Other advisors: Dr Kathryn Kemper, Professor Loic Yengo

  • Doctor Philosophy

    Genetic architecture and evolution of complex traits across populations in humans

    Associate Advisor

    Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng

  • Doctor Philosophy

    Integrating GWAS and molecular QTL data to dissect genetic architecture and improve polygenic prediction

    Associate Advisor

    Other advisors: Dr Jian Zeng

Completed supervision

Media

Enquiries

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