Professor Allan McRae
Professor

Allan McRae

Email: 

Availability

Professor Allan McRae is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Edinburgh

Search Professor Allan McRae’s works on UQ eSpace

194 works between 2002 and 2026
All (194) Journal Article (175) Other Outputs (1) Conference Publication (16) Book Chapter (2)

81 - 100 of 194 works

2019

Book Chapter

A Cache-based data movement infrastructure for on-demand scientific cloud computing

Abramson, David, Carroll, Jake, Jin, Chao, Mallon, Michael, van Iperen, Zane, Nguyen, Hoang, McRae, Allan and Ming, Liang (2019). A Cache-based data movement infrastructure for on-demand scientific cloud computing. Supercomputing frontiers. (pp. 38-56) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-18645-6_3

A Cache-based data movement infrastructure for on-demand scientific cloud computing

2019

Conference Publication

Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium

Mortlock, Sally, Fung, Jenny N., Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Lukowski, Samuel W., McKinnon, Brett D., Yang, Jian, McRae, Allan, Rogers, Peter A. W. and Montgomery, Grant W. (2019). Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.

Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium

2019

Conference Publication

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

2018

Journal Article

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Stevenson, Anna J., McCartney, Daniel L., Harris, Sarah E., Taylor, Adele M., Redmond, Paul, Starr, John M., Zhang, Qian, McRae, Allan F., Wray, Naomi R., Spires-Jones, Tara L., McColl, Barry W., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2018). Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing. Clinical Epigenetics, 10 (1) 159, 159. doi: 10.1186/s13148-018-0585-x

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

2018

Journal Article

Identification of 55,000 replicated DNA methylation QTL

McRae, Allan F., Marioni, Riccardo E., Shah, Sonia, Yang, Jian, Powell, Joseph E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Bowdler, Lisa, Painter, Jodie N., Murphy, Lee, Martin, Nicholas G., Starr, John M., Wray, Naomi R., Deary, Ian J., Visscher, Peter M. and Montgomery, Grant W. (2018). Identification of 55,000 replicated DNA methylation QTL. Scientific Reports, 8 (1) 17605, 17605. doi: 10.1038/s41598-018-35871-w

Identification of 55,000 replicated DNA methylation QTL

2018

Journal Article

Genotype effects contribute to variation in longitudinal methylome patterns in older people

Zhang, Qian, Marioni, Riccardo E., Robinson, Matthew R., Higham, Jon, Sproul, Duncan, Wray, Naomi R., Deary, Ian J., McRae, Allan F. and Visscher, Peter M. (2018). Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine, 10 (1) 75, 75. doi: 10.1186/s13073-018-0585-7

Genotype effects contribute to variation in longitudinal methylome patterns in older people

2018

Journal Article

Epigenetic prediction of complex traits and death

McCartney, Daniel L., Hillary, Robert F., Stevenson, Anna J., Ritchie, Stuart J., Walker, Rosie M., Zhang, Qian, Morris, Stewart W., Bermingham, Mairead L., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Gale, Catharine R., Porteous, David J., Haley, Chris S., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J. and Marioni, Riccardo E. (2018). Epigenetic prediction of complex traits and death. Genome Biology, 19 (1) 136, 136. doi: 10.1186/s13059-018-1514-1

Epigenetic prediction of complex traits and death

2018

Journal Article

Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome

Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Zhu, Zhihong, Lukowski, Samuel W., McKinnon, Brett D., McRae, Allan, Yang, Jian, Healey, Martin, Powell, Joseph E., Rogers, Peter A. W. and Montgomery, Grant W (2018). Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome. Scientific Reports, 8 (1) 11424, 11424. doi: 10.1038/s41598-018-29462-y

Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome

2018

Journal Article

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

Xue, Angli, Wu, Yang, Zhu, Zhihong, Zhang, Futao, Kemper, Kathryn E., Zheng, Zhili, Yengo, Loic, Lloyd-Jones, Luke R., Sidorenko, Julia, Wu, Yeda, eQTLGen Consortium, McRae, Allan F., Visscher, Peter M., Zeng, Jian and Yang, Jian (2018). Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications, 9 (1) 2941, 2941. doi: 10.1038/s41467-018-04951-w

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

2018

Journal Article

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

Story Jovanova, Olivera, Nedeljkovic, Ivana, Derek, Spieler, Walker, Rosie M., Liu, Chunyu, Luciano, Michelle, Bressler, Jan, Brody, Jennifer, Drake, Amanda J., Evans, Kathryn L., Gondalia, Rahul, Kunze, Sonja, Kuhnel, Brigitte, Lahti, Jari, Lemaitre, Rozenn N., Marioni, Riccardo E., Swenson, Brenton, Himali, Jayandra Jung, Wu, Hongsheng, Li, Yun, McRae, Allan F., Russ, Tom C., Stewart, James, Wang, Zhiying, Zhang, Guosheng, Ladwig, Karl-Heinz, Uitterlinden, Andre G., Guo, Xiuqing, Peters, Annette ... Amin, Najaf (2018). DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies. JAMA Psychiatry, 75 (9), 949-959. doi: 10.1001/jamapsychiatry.2018.1725

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

2018

Journal Article

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, eQTLGen Consortium, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications, 9 (1) 2282, 2282. doi: 10.1038/s41467-018-04558-1

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

2018

Journal Article

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

Cuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M., Gaunt, Tom R., McRae, Allan, Visscher, Peter M., Montgomery, Grant W., Martin, Nicholas G., Hemani, Gibran, Suderman, Matthew, Relton, Caroline L., Davey Smith, George and Evans, David M. (2018). Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. Human Molecular Genetics, 27 (16), 2927-2939. doi: 10.1093/hmg/ddy206

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

2018

Journal Article

GWAS on family history of Alzheimer's disease

Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer's disease. Translational Psychiatry, 8 (1) 99, 99. doi: 10.1038/s41398-018-0150-6

GWAS on family history of Alzheimer's disease

2018

Journal Article

Signatures of negative selection in the genetic architecture of human complex traits

Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, McRae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. Nature Genetics, 50 (5), 746-753. doi: 10.1038/s41588-018-0101-4

Signatures of negative selection in the genetic architecture of human complex traits

2018

Journal Article

Genome-wide average DNA methylation is determined in utero

Li, Shuai, Wong, Ee Ming, Dugué, Pierre-Antoine, McRae, Allan F., Kim, Eunae, Joo, Ji-Hoon Eric, Nguyen, Tuong L, Stone, Jennifer, Dite, Gillian S, Armstrong, Nicola J, Mather, Karen A, Thalamuthu, Anbupalam, Wright, Margaret J., Ames, David, Milne, Roger L, Craig, Jeffrey M, Saffery, Richard, Montgomery, Grant W., Song, Yun-Mi, Sung, Joohon, Spector, Timothy D, Sachdev, Perminder S, Giles, Graham G, Southey, Melissa C and Hopper, John L (2018). Genome-wide average DNA methylation is determined in utero. International Journal of Epidemiology, 47 (3), 908-916. doi: 10.1093/ije/dyy028

Genome-wide average DNA methylation is determined in utero

2018

Journal Article

Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

Wu, Yang, Zeng, Jian, Zhang, Futao, Zhu, Zhihong, Qi, Ting, Zheng, Zhili, Lloyd-Jones, Luke R., Marioni, Riccardo E., Martin, Nicholas G., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits. Nature Communications, 9 (918) 918, 918. doi: 10.1038/s41467-018-03371-0

Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

2018

Journal Article

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

Lu, Ake T., Xue, Luting, Salfati, Elias L., Chen, Brian H., Ferrucci, Luigi, Levy, Daniel, Joehanes, Roby, Murabito, Joanne M., Kiel, Douglas P., Tsai, Pei-Chien, Yet, Idil, Bell, Jordana T., Mangino, Massimo, Tanaka, Toshiko, McRae, Allan F., Marioni, Riccardo E., Visscher, Peter M., Wray, Naomi R., Deary, Ian J., Levine, Morgan E., Quach, Austin, Assimes, Themistocles, Tsao, Philip S., Absher, Devin, Stewart, James D., Li, Yun, Reiner, Alex P., Hou, Lifang, Baccarelli, Andrea A. ... Horvath, Steve (2018). GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications, 9 (1) 387, 387. doi: 10.1038/s41467-017-02697-5

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

2018

Journal Article

Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Gerring, Zachary F., McRae, Allan F., Montgomery, Grant W. and Nyholt, Dale R. (2018). Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine. BMC Genomics, 19 (1) 69, 69. doi: 10.1186/s12864-018-4450-2

Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

2018

Journal Article

Meta-analysis of epigenome-wide association studies of cognitive abilities

Marioni, Riccardo E., McRae, Allan F, Bressler, Jan, Colicino, Elena, Hannon, Eilis, Li, Shuo, Prada, Diddier, Smith, Jennifer A, Trevisi, Letizia, Tsai, Pei-Chien, Vojinovic, Dina, Simino, Jeannette, Levy, Daniel, Liu, Chunyu, Mendelson, Michael, Satizabal, Claudia L, Yang, Qiong, Jhun, Min A, Kardia, Sharon L R, Zhao, Wei, Bandinelli, Stefania, Ferrucci, Luigi, Hernandez, Dena G, Singleton, Andrew B, Harris, Sarah E, Starr, John M, Kiel, Douglas P, McLean, Robert R, Just, Allan C ... Deary, Ian J (2018). Meta-analysis of epigenome-wide association studies of cognitive abilities. Molecular Psychiatry, 23 (11), 2133-2144. doi: 10.1038/s41380-017-0008-y

Meta-analysis of epigenome-wide association studies of cognitive abilities

2018

Journal Article

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Wang, Yunzhang, Karlsson, Robert, Lampa, Erik, Zhang, Qian, Hedman, Åsa K., Almgren, Malin, Almqvist, Catarina, McRae, Allan F., Marioni, Riccardo E., Ingelsson, Erik, Visscher, Peter M., Deary, Ian J., Lind, Lars, Morris, Tiffany, Beck, Stephan, Pedersen, Nancy L. and Hägg, Sara (2018). Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins. Epigenetics, 13 (9), 1-13. doi: 10.1080/15592294.2018.1526028

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Current funding

  • 2026 - 2029
    Developing and Applying Novel Polygenic Score Approaches in ALS for Risk Prediction, Stratification, and Precision Medicine
    FightMND Discovery Grant
    Open grant
  • 2025 - 2027
    Proteomic Biomarkers for ALS Disease Prognosis and Progression Monitoring
    United States Congressionally Directed Medical Research Programs - Amyotrophic Lateral Sclerosis Research Program
    Open grant

Past funding

  • 2024 - 2026
    SALSA Study with MND and Me Foundation
    The MND and ME Foundation
    Open grant
  • 2023 - 2024
    An Australian Sporadic ALS transcriptome resource
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2022 - 2025
    MAGNET - A multi-arm, adaptive, group-sequential trial network to evaluate drug efficacy in patients with Amyotrophic Lateral Sclerosis (ALS) (FightMND grant administered by NeuRA)
    Neuroscience Research Australia
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease (EU-JPND grant coordinated by Institut du Cerveau et de la Moelle épinière)
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    A high-throughput system to identify ALS risk genes from genome-wide association studies
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2020 - 2024
    Genomic Control of Human Complex Trait Variation
    ARC Future Fellowships
    Open grant
  • 2020 - 2025
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Cure for MND Foundation - Translational Research Grants
    Open grant
  • 2019 - 2020
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health (NHMRC A*STAR grant led by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2018 - 2021
    BRAIN-MEND: Biological Resource Analysis to identify new mechanisms and phenotypes in Neurodegenerative Diseases (NHMRC component of EU JPND application)
    NHMRC Boosting Dementia Research Grants
    Open grant
  • 2018 - 2019
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health
    NHMRC A*STAR Joint Grants
    Open grant
  • 2016 - 2020
    Methods and software tool for complex trait analyses using multi-omics data
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    Genetics of DNA Methylation and Its Role in Disease Susecptibility
    NHMRC Career Development Fellowship
    Open grant
  • 2015 - 2018
    The importance of DNA methylation in response to environmental changes (ARC Discovery Project administered by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2012 - 2014
    Inheritance of DNA methylation state in humans
    NHMRC Project Grant
    Open grant

Availability

Professor Allan McRae is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Leveraging multi-omic and epidemiological data to understand endometriosis and its symptomatology

    Principal Advisor

    Other advisors: Professor Naomi Wray, Dr Sally Mortlock

  • Doctor Philosophy

    Genetics of Neurodevelopmental Disorders and associated comorbidities

    Associate Advisor

    Other advisors: Dr Enda Byrne

  • Doctor Philosophy

    Cellular genomics of Parkinson's disease

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Honorary Professor Jake Gratten, Dr Yuanhao Yang

  • Doctor Philosophy

    Identifying serum biomarkers correlated with longitudinal and cross-sectional trends in PFAS serum concentration using metabolomics.

    Associate Advisor

    Other advisors: Dr Sandra Nilsson, Professor Jochen Mueller

  • Doctor Philosophy

    Multiomics of common co-occurring conditions in autism spectrum disorder

    Associate Advisor

    Other advisors: Dr Yuanhao Yang, Honorary Professor Jake Gratten

  • Doctor Philosophy

    Novel methods and data integration to understand the causes of Amyotrophic Lateral Sclerosis

    Associate Advisor

    Other advisors: Dr Jian Zeng, Dr Fleur Garton

  • Doctor Philosophy

    Exploring the role of epidemiological and molecular factors in endometriosis risk

    Associate Advisor

    Other advisors: Dr Sally Mortlock

Completed supervision

Enquiries

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