Professor Allan McRae
Professor

Allan McRae

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Availability

Professor Allan McRae is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Edinburgh

Search Professor Allan McRae’s works on UQ eSpace

194 works between 2002 and 2026
All (194) Journal Article (175) Other Outputs (1) Conference Publication (16) Book Chapter (2)

101 - 120 of 194 works

2018

Journal Article

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

Sønderby, Ida Elken, Gústafsson, Ómar, Doan, Nhat Trung, Hibar, Derrek Paul, Martin-Brevet, Sandra, Westlye, Lars T., Jacquemont, Sébastien, Djurovic, Srdjan, Stefánsson, Hreinn, Stefánsson, Kari, Thompson, Paul M., Andreassen, Ole A., McRae, Allan, Strike, Lachlan, McMahon, Katie L., Wright, Margie and for the 16p11.2 European Consortium, for the ENIGMA-CNV working group (2018). Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia. Molecular Psychiatry, 25 (3), 584-602. doi: 10.1038/s41380-018-0118-1

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia

2018

Conference Publication

Fine-mapping reveals complex genetic architecture underlying DNA methylation

Chundru, V. Kartik, Marioni, Riccardo E., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2018). Fine-mapping reveals complex genetic architecture underlying DNA methylation. Human Genome Meeting, Yokohama, Japan, 12-15 March 2018. London, United Kingdom: Henry Stewart Publications. doi: 10.1186/s40246-018-0138-6

Fine-mapping reveals complex genetic architecture underlying DNA methylation

2018

Conference Publication

Signatures of negative selection in the genetic architecture of human complex traits

Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, Mcrae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. 48th Annual Meeting of the Behavior-Genetics-Association (BGA), Boston MA, United States, 20-23 June 2018. New York, NY United States: Springer New York.

Signatures of negative selection in the genetic architecture of human complex traits

2017

Journal Article

DNA methylation analysis identifies loci for blood pressure regulation

Richard, Melissa A., Huan, Tianxiao, Ligthart, Symen, Gondalia, Rahul, Jhun, Min A., Brody, Jennifer A., Irvin, Marguerite R., Marioni, Riccardo, Shen, Jincheng, Tsai, Pei-Chien, Montasser, May E., Jia, Yucheng, Syme, Catriona, Salfati, Elias L., Boerwinkle, Eric, Guan, Weihua, Mosley, Thomas H., Bressler, Jan, Morrison, Alanna C., Liu, Chunyu, Mendelson, Michael M., Uitterlinden, André G., van Meurs, Joyce B., Heijmans, Bastiaan T., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Jansen, Rick, Franke, Lude ... Fornage, Myriam (2017). DNA methylation analysis identifies loci for blood pressure regulation. American Journal of Human Genetics, 101 (6), 888-902. doi: 10.1016/j.ajhg.2017.09.028

DNA methylation analysis identifies loci for blood pressure regulation

2017

Journal Article

Testing two evolutionary theories of human aging with DNA methylation data

Robins, Chloe, McRae, Allan F., Powell, Joseph E., Wiener, Howard W., Aslibekyan, Stella, Kennedy, Elizabeth M., Absher, Devin M., Arnett, Donna K., Montgomery, Grant W., Visscher, Peter M., Cutler, David J. and Conneely, Karen N. (2017). Testing two evolutionary theories of human aging with DNA methylation data. Genetics, 207 (4), 1547-1560. doi: 10.1534/genetics.117.300217

Testing two evolutionary theories of human aging with DNA methylation data

2017

Journal Article

An epigenome-wide association study meta-analysis of educational attainment

Karlsson Linnér, R., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davies, N. M., Watanabe, K., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S, Lahti, J., McRae, A. F., Mandaviya, P. R., Seppälä, I., Wang, Y., Baglietto, L., Binder, E. B., Harris, S. E., Hodge, A. M., Horvath, S., Hurme, M., Johannesson, M. ... Benjamin, D. J. (2017). An epigenome-wide association study meta-analysis of educational attainment. Molecular Psychiatry, 22 (12), 1680-1690. doi: 10.1038/mp.2017.210

An epigenome-wide association study meta-analysis of educational attainment

2017

Journal Article

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

Mandaviya, Pooja R., Joehanes, Roby, Aïssi, Dylan, Kühnel, Brigitte, Marioni, Riccardo E., Truong, Vinh, Stolk, Lisette, Beekman, Marian, Bonder, Marc Jan, Franke, Lude, Gieger, Christian, Huan, Tianxiao, Ikram, M. Arfan, Kunze, Sonja, Liang, Liming, Lindemans, Jan, Liu, Chunyu, McRae, Allan F., Mendelson, Michael M., Müller-Nurasyid, Martina, Peters, Annette, Slagboom, P. Eline, Starr, John M., Trégouët, David-Alexandre, Uitterlinden, André G., van Greevenbroek, Marleen M. J., van Heemst, Diana, van Iterson, Maarten, Wells, Philip S. ... van Meurs, Joyce B. J. (2017). Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. PLoS One, 12 (10) e0182472, e0182472. doi: 10.1371/journal.pone.0182472

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

2017

Journal Article

Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort

Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302

Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort

2017

Journal Article

Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor

Elliott, Hannah R., Shihab, Hashem A., Lockett, Gabrielle A., Holloway, John W., McRae, Allan F., Smith, George Davey, Ring, Susan M., Gaunt, Tom R. and Relton, Caroline L. (2017). Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor. Diabetes, 66 (6), 1713-1722. doi: 10.2337/db16-0874

Role of DNA methylation in type 2 diabetes etiology: using genotype as a causal anchor

2017

Journal Article

Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies

Hedman, Åsa K., Mendelson, Michael M., Marioni, Riccardo E., Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R., Zhi, Degui, Sandling, Johanna K., Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Tianxiao, McRae, Allan F., Demissie, Serkalem, Shah, Sonia, Starr, John M., Cupples, L. Adrienne, Deloukas, Panos, Spector, Timothy D., Sundstrom, Johan, Krauss, Ronald M., Arnett, Donna K., Deary, Ian J., Lind, Lars, Levy, Daniel and Ingelsson, Erik (2017). Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies. Circulation: Cardiovascular Genetics, 10 (1) 001487. doi: 10.1161/CIRCGENETICS.116.001487

Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies

2017

Journal Article

The Genetic Architecture of Gene Expression in Peripheral Blood (vol 100, pg 228, 2017)

Lloyd-Jones, Luke R., Holloway, Alexander, McRae, Allan, Yang, Jian, Small, Kerrin, Zhao, Jing, Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Dermitzakis, Manolis, Gibson, Greg, Spector, Tim, Montgomery, Grant, Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017). The Genetic Architecture of Gene Expression in Peripheral Blood (vol 100, pg 228, 2017). American Journal of Human Genetics, 100 (2), 371-371. doi: 10.1016/j.ajhg.2017.01.026

The Genetic Architecture of Gene Expression in Peripheral Blood (vol 100, pg 228, 2017)

2017

Journal Article

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan, North, Kari, Sundstrom, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F., Harris, Sarah E., Gibson, Jude, Redmond, Paul, Corley, Janie ... Deary, Ian J. (2017). Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach. PLoS Medicine, 14 (1) e1002215, e1002215. doi: 10.1371/journal.pmed.1002215

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

2017

Journal Article

The genetic architecture of gene expression in peripheral blood

Lloyd-Jones, Luke R., Holloway, Alexander, McRae, Allan, Yang, Jian, Small, Kerrin, Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Dermitzakis, Manolis, Gibson, Greg, Spector, Tim, Montgomery, Grant, Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017). The genetic architecture of gene expression in peripheral blood. American Journal of Human Genetics, 100 (2), 228-237. doi: 10.1016/j.ajhg.2016.12.008

The genetic architecture of gene expression in peripheral blood

2017

Book Chapter

Analysis of genome-wide association data

McRae, Allan F. (2017). Analysis of genome-wide association data. Bioinformatics. Volume II: structure, function, and applications. (pp. 161-173) edited by Jonathan M. Keith. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-6613-4_9

Analysis of genome-wide association data

2017

Conference Publication

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

2017

Conference Publication

Tissue-specific sexual dimorphism in autosomal gene expression

Kassam, Irfahan, Wu, Yang, Visscher, Peter M. and McRae, Allan F. (2017). Tissue-specific sexual dimorphism in autosomal gene expression. Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Cambridge, England, 9-11 September 2017. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/gepi.22062

Tissue-specific sexual dimorphism in autosomal gene expression

2016

Journal Article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., Elks, Cathy, Marioni, Riccardo, Jhun, Min A., Agha, Golareh, Bressler, Jan, Ward-Caviness, Cavin K., Chen, Brian H., Huan, Tianxiao, Bakulski, Kelly, Salfati, Elias L., Fiorito, Giovanni, Wahl, Simone, Schramm, Katharina, Sha, Jin, Hernandez, Dena G., Just, Allan C., Smith, Jennifer A., Sotoodehnia, Nona ... Dehghan, Abbas (2016). DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology, 17 (1) 255, 255-255. doi: 10.1186/s13059-016-1119-5

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

2016

Journal Article

Autosomal genetic control of human gene expression does not differ across the sexes

Kassam, Irfahan, Lloyd-Jones, Luke, Holloway, Alexander, Small, Kerrin S., Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Gibson, Greg, Spector, Tim D., Esko, Tonu, Montgomery, Grant W., Powell, Joseph E., Yang, Jian, Visscher, Peter M. and McRae, Allan F. (2016). Autosomal genetic control of human gene expression does not differ across the sexes. Genome Biology, 17 (1) 248, 248.1-248.10. doi: 10.1186/s13059-016-1111-0

Autosomal genetic control of human gene expression does not differ across the sexes

2016

Journal Article

A DNA methylation biomarker of alcohol consumption

Liu, C., Marioni, R. E., Hedman, K., Pfeiffer, L., Tsai, P. -C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C., Mendelson, M. M., Joehanes, R., Liang, L., Love, S. -A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H. ... Levy, D. (2016). A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry, 23 (2), 422-433. doi: 10.1038/mp.2016.192

A DNA methylation biomarker of alcohol consumption

2016

Journal Article

Evidence for mitochondrial genetic control of autosomal gene expression

Kassam, Irfahan, Qi, Tuan, Lloyd-Jones, Luke, Holloway, Alexander, Bonder, Marc Jan, Henders, Anjali K., Martin, Nicholas G., Powell, Joseph E., Franke, Lude, Montgomery, Grant W., Visscher, Peter M. and McRae, Allan F. (2016). Evidence for mitochondrial genetic control of autosomal gene expression. Human Molecular Genetics, 25 (24), 5332-5338. doi: 10.1093/hmg/ddw347

Evidence for mitochondrial genetic control of autosomal gene expression

Current funding

  • 2026 - 2029
    Developing and Applying Novel Polygenic Score Approaches in ALS for Risk Prediction, Stratification, and Precision Medicine
    FightMND Discovery Grant
    Open grant
  • 2025 - 2027
    Proteomic Biomarkers for ALS Disease Prognosis and Progression Monitoring
    United States Congressionally Directed Medical Research Programs - Amyotrophic Lateral Sclerosis Research Program
    Open grant

Past funding

  • 2024 - 2026
    SALSA Study with MND and Me Foundation
    The MND and ME Foundation
    Open grant
  • 2023 - 2024
    An Australian Sporadic ALS transcriptome resource
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2022 - 2025
    MAGNET - A multi-arm, adaptive, group-sequential trial network to evaluate drug efficacy in patients with Amyotrophic Lateral Sclerosis (ALS) (FightMND grant administered by NeuRA)
    Neuroscience Research Australia
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease (EU-JPND grant coordinated by Institut du Cerveau et de la Moelle épinière)
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    A high-throughput system to identify ALS risk genes from genome-wide association studies
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2020 - 2024
    Genomic Control of Human Complex Trait Variation
    ARC Future Fellowships
    Open grant
  • 2020 - 2025
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Cure for MND Foundation - Translational Research Grants
    Open grant
  • 2019 - 2020
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health (NHMRC A*STAR grant led by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2018 - 2021
    BRAIN-MEND: Biological Resource Analysis to identify new mechanisms and phenotypes in Neurodegenerative Diseases (NHMRC component of EU JPND application)
    NHMRC Boosting Dementia Research Grants
    Open grant
  • 2018 - 2019
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health
    NHMRC A*STAR Joint Grants
    Open grant
  • 2016 - 2020
    Methods and software tool for complex trait analyses using multi-omics data
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    Genetics of DNA Methylation and Its Role in Disease Susecptibility
    NHMRC Career Development Fellowship
    Open grant
  • 2015 - 2018
    The importance of DNA methylation in response to environmental changes (ARC Discovery Project administered by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2012 - 2014
    Inheritance of DNA methylation state in humans
    NHMRC Project Grant
    Open grant

Availability

Professor Allan McRae is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Leveraging multi-omic and epidemiological data to understand endometriosis and its symptomatology

    Principal Advisor

    Other advisors: Professor Naomi Wray, Dr Sally Mortlock

  • Doctor Philosophy

    Novel methods and data integration to understand the causes of Amyotrophic Lateral Sclerosis

    Associate Advisor

    Other advisors: Dr Jian Zeng, Dr Fleur Garton

  • Doctor Philosophy

    Exploring the role of epidemiological and molecular factors in endometriosis risk

    Associate Advisor

    Other advisors: Dr Sally Mortlock

  • Doctor Philosophy

    Genetics of Neurodevelopmental Disorders and associated comorbidities

    Associate Advisor

    Other advisors: Dr Enda Byrne

  • Doctor Philosophy

    Cellular genomics of Parkinson's disease

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Honorary Professor Jake Gratten, Dr Yuanhao Yang

  • Doctor Philosophy

    Identifying serum biomarkers correlated with longitudinal and cross-sectional trends in PFAS serum concentration using metabolomics.

    Associate Advisor

    Other advisors: Dr Sandra Nilsson, Professor Jochen Mueller

  • Doctor Philosophy

    Multiomics of common co-occurring conditions in autism spectrum disorder

    Associate Advisor

    Other advisors: Dr Yuanhao Yang, Honorary Professor Jake Gratten

Completed supervision

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