Dr Allan McRae
Dr

Allan McRae

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Availability

Dr Allan McRae is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Edinburgh

Search Professor Allan McRae’s works on UQ eSpace

184 works between 2002 and 2025
All (184) Journal Article (160) Book Chapter (2) Conference Publication (10) Other Outputs (12)

101 - 120 of 184 works

2017

Journal Article

Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies

Hedman, Åsa K., Mendelson, Michael M., Marioni, Riccardo E., Gustafsson, Stefan, Joehanes, Roby, Irvin, Marguerite R., Zhi, Degui, Sandling, Johanna K., Yao, Chen, Liu, Chunyu, Liang, Liming, Huan, Tianxiao, McRae, Allan F., Demissie, Serkalem, Shah, Sonia, Starr, John M., Cupples, L. Adrienne, Deloukas, Panos, Spector, Timothy D., Sundstrom, Johan, Krauss, Ronald M., Arnett, Donna K., Deary, Ian J., Lind, Lars, Levy, Daniel and Ingelsson, Erik (2017). Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies. Circulation: Cardiovascular Genetics, 10 (1) 001487. doi: 10.1161/CIRCGENETICS.116.001487

Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies

2017

Journal Article

The Genetic Architecture of Gene Expression in Peripheral Blood (vol 100, pg 228, 2017)

Lloyd-Jones, Luke R., Holloway, Alexander, McRae, Allan, Yang, Jian, Small, Kerrin, Zhao, Jing, Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Dermitzakis, Manolis, Gibson, Greg, Spector, Tim, Montgomery, Grant, Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017). The Genetic Architecture of Gene Expression in Peripheral Blood (vol 100, pg 228, 2017). American Journal of Human Genetics, 100 (2), 371-371. doi: 10.1016/j.ajhg.2017.01.026

The Genetic Architecture of Gene Expression in Peripheral Blood (vol 100, pg 228, 2017)

2017

Journal Article

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan, North, Kari, Sundstrom, Johan, Gustafsson, Stefan, Shah, Sonia, McRae, Allan F., Harris, Sarah E., Gibson, Jude, Redmond, Paul, Corley, Janie ... Deary, Ian J. (2017). Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach. PLoS Medicine, 14 (1) e1002215, e1002215. doi: 10.1371/journal.pmed.1002215

Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach

2017

Journal Article

The genetic architecture of gene expression in peripheral blood

Lloyd-Jones, Luke R., Holloway, Alexander, McRae, Allan, Yang, Jian, Small, Kerrin, Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Dermitzakis, Manolis, Gibson, Greg, Spector, Tim, Montgomery, Grant, Esko, Tonu, Visscher, Peter M. and Powell, Joseph E. (2017). The genetic architecture of gene expression in peripheral blood. American Journal of Human Genetics, 100 (2), 228-237. doi: 10.1016/j.ajhg.2016.12.008

The genetic architecture of gene expression in peripheral blood

2017

Book Chapter

Analysis of genome-wide association data

McRae, Allan F. (2017). Analysis of genome-wide association data. Bioinformatics. Volume II: structure, function, and applications. (pp. 161-173) edited by Jonathan M. Keith. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-6613-4_9

Analysis of genome-wide association data

2017

Conference Publication

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

2017

Conference Publication

Tissue-specific sexual dimorphism in autosomal gene expression

Kassam, Irfahan, Wu, Yang, Visscher, Peter M. and McRae, Allan F. (2017). Tissue-specific sexual dimorphism in autosomal gene expression. Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Cambridge, England, 9-11 September 2017. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/gepi.22062

Tissue-specific sexual dimorphism in autosomal gene expression

2016

Journal Article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen, Marzi, Carola, Aslibekyan, Stella, Mendelson, Michael M., Conneely, Karen N., Tanaka, Toshiko, Colicino, Elena, Waite, Lindsay L., Joehanes, Roby, Guan, Weihua, Brody, Jennifer A., Elks, Cathy, Marioni, Riccardo, Jhun, Min A., Agha, Golareh, Bressler, Jan, Ward-Caviness, Cavin K., Chen, Brian H., Huan, Tianxiao, Bakulski, Kelly, Salfati, Elias L., Fiorito, Giovanni, Wahl, Simone, Schramm, Katharina, Sha, Jin, Hernandez, Dena G., Just, Allan C., Smith, Jennifer A., Sotoodehnia, Nona ... Dehghan, Abbas (2016). DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology, 17 (1) 255, 255-255. doi: 10.1186/s13059-016-1119-5

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

2016

Journal Article

Autosomal genetic control of human gene expression does not differ across the sexes

Kassam, Irfahan, Lloyd-Jones, Luke, Holloway, Alexander, Small, Kerrin S., Zeng, Biao, Bakshi, Andrew, Metspalu, Andres, Gibson, Greg, Spector, Tim D., Esko, Tonu, Montgomery, Grant W., Powell, Joseph E., Yang, Jian, Visscher, Peter M. and McRae, Allan F. (2016). Autosomal genetic control of human gene expression does not differ across the sexes. Genome Biology, 17 (1) 248, 248.1-248.10. doi: 10.1186/s13059-016-1111-0

Autosomal genetic control of human gene expression does not differ across the sexes

2016

Journal Article

A DNA methylation biomarker of alcohol consumption

Liu, C., Marioni, R. E., Hedman, K., Pfeiffer, L., Tsai, P. -C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C., Mendelson, M. M., Joehanes, R., Liang, L., Love, S. -A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H. ... Levy, D. (2016). A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry, 23 (2), 422-433. doi: 10.1038/mp.2016.192

A DNA methylation biomarker of alcohol consumption

2016

Journal Article

Evidence for mitochondrial genetic control of autosomal gene expression

Kassam, Irfahan, Qi, Tuan, Lloyd-Jones, Luke, Holloway, Alexander, Bonder, Marc Jan, Henders, Anjali K., Martin, Nicholas G., Powell, Joseph E., Franke, Lude, Montgomery, Grant W., Visscher, Peter M. and McRae, Allan F. (2016). Evidence for mitochondrial genetic control of autosomal gene expression. Human Molecular Genetics, 25 (24), 5332-5338. doi: 10.1093/hmg/ddw347

Evidence for mitochondrial genetic control of autosomal gene expression

2016

Journal Article

Epigenetic signatures of cigarette smoking

Joehanes, Roby, Just, Allan C., Marioni, Riccardo E., Pilling, Luke C., Reynolds, Lindsay M., Mandaviya, Pooja R., Guan, Weihua, Xu, Tao, Elks, Cathy E., Aslibekyan, Stella, Moreno-Macias, Hortensia, Smith, Jennifer A., Brody, Jennifer A., Dhingra, Radhika, Yousefi, Paul, Pankow, James S., Kunze, Sonja, Shah, Sonia H., McRae, Allan F., Lohman, Kurt, Sha, Jin, Absher, Devin M., Ferrucci, Luigi, Zhao, Wei, Demerath, Ellen W., Bressler, Jan, Grove, Megan L., Huan, Tianxiao, Liu, Chunyu ... London, Stephanie J. (2016). Epigenetic signatures of cigarette smoking. Circulation: Cardiovascular Genetics, 9 (5), 436-447. doi: 10.1161/CIRCGENETICS.116.001506

Epigenetic signatures of cigarette smoking

2016

Journal Article

Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits

Bakshi, Andrew, Zhu, Zhihong, Vinkhuyzen, Anna A. E., Hill, W. David, Mcrae, Allan F., Visscher, Peter M. and Yang, Jian (2016). Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits. Scientific Reports, 6 (1) 32894, 32894. doi: 10.1038/srep32894

Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits

2016

Journal Article

The autosomal genetic control of sexually dimorphic traits in humans is largely the same across the sexes

Kassam, Irfahan and McRae, Allan F. (2016). The autosomal genetic control of sexually dimorphic traits in humans is largely the same across the sexes. Genome Biology, 17 (1) 169. doi: 10.1186/s13059-016-1035-8

The autosomal genetic control of sexually dimorphic traits in humans is largely the same across the sexes

2016

Journal Article

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

Pavlides, Jennifer M. Whitehead, Zhu, Zhihong, Gratten, Jacob, Mcrae, Allan F., Wray, Naomi R. and Yang, Jian (2016). Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Medicine, 8 (1) 84, 84. doi: 10.1186/s13073-016-0338-4

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

2016

Journal Article

Identification of common genetic variants influencing spontaneous dizygotic twinning and female fertility

Mbarek, Hamdi, Steinberg, Stacy, Nyholt, Dale R., Gordon, Scott D., Miller, Michael B., McRae, Allan F, Hottenga, Jouke Jan, Day, Felix R., Willemsen, Gonneke, de Geus, Eco J., Davies, Gareth E, Martin, Hilary C, Penninx, Brenda W, Jansen, Rick, McAloney, Kerrie, Vink, Jacqueline M., Kaprio, Jaakko, Plomin, Robert, Spector, Tim D., Magnusson, Patrik K., Reversade, Bruno, Harris, R. Alan, Aagaard, Kjersti, Kristjansson, Ragnar P., Olafsson, Isleifur, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Iacono, William G., Lambalk, Cornelis B ... Boomsman, Dorret I. (2016). Identification of common genetic variants influencing spontaneous dizygotic twinning and female fertility. American Journal of Human Genetics, 98 (5), 898-908. doi: 10.1016/j.ajhg.2016.03.008

Identification of common genetic variants influencing spontaneous dizygotic twinning and female fertility

2016

Journal Article

Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041

Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016). Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041. International Journal of Epidemiology, 47 (1) dyx217, 356-356. doi: 10.1093/ije/dyx233

Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041

2016

Journal Article

The epigenetic clock and telomere length are independently associated with chronological age and mortality

Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016). The epigenetic clock and telomere length are independently associated with chronological age and mortality. International Journal of Epidemiology, 45 (2), 424-432. doi: 10.1093/ije/dyw041

The epigenetic clock and telomere length are independently associated with chronological age and mortality

2016

Journal Article

Shared genetic control of expression and methylation in peripheral blood

Shakhbazov, Konstantin, Powell, Joseph E., Hemani, Gibran, Henders, Anjali K., Martin, Nicholas G., Visscher, Peter M., Montgomery, Grant W. and McRae, Allan F. (2016). Shared genetic control of expression and methylation in peripheral blood. BMC Genomics, 17 (1) 278, 278. doi: 10.1186/s12864-016-2498-4

Shared genetic control of expression and methylation in peripheral blood

2016

Journal Article

Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes

Tseng, Hsu-Wen, Pitt, Miranda E., Glant, Tibor T., McRae, Allan F., Kenna, Tony J., Brown, Matthew A., Pettit, Allison R. and Thomas, Gethin P. (2016). Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes. Arthritis Research and Therapy, 18 (1) 35, 35. doi: 10.1186/s13075-015-0805-0

Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes

Current funding

  • 2025 - 2027
    Proteomic Biomarkers for ALS Disease Prognosis and Progression Monitoring
    United States Congressionally Directed Medical Research Programs - Amyotrophic Lateral Sclerosis Research Program
    Open grant
  • 2024 - 2025
    SALSA Study with MND and Me Foundation
    The MND and ME Foundation
    Open grant
  • 2022 - 2025
    MAGNET - A multi-arm, adaptive, group-sequential trial network to evaluate drug efficacy in patients with Amyotrophic Lateral Sclerosis (ALS) (FightMND grant administered by NeuRA)
    Neuroscience Research Australia
    Open grant
  • 2020 - 2025
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Cure for MND Foundation - Translational Research Grants
    Open grant

Past funding

  • 2023 - 2024
    An Australian Sporadic ALS transcriptome resource
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease (EU-JPND grant coordinated by Institut du Cerveau et de la Moelle épinière)
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    A high-throughput system to identify ALS risk genes from genome-wide association studies
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2020 - 2024
    Genomic Control of Human Complex Trait Variation
    ARC Future Fellowships
    Open grant
  • 2019 - 2020
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health (NHMRC A*STAR grant led by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2018 - 2021
    BRAIN-MEND: Biological Resource Analysis to identify new mechanisms and phenotypes in Neurodegenerative Diseases (NHMRC component of EU JPND application)
    NHMRC Boosting Dementia Research Grants
    Open grant
  • 2018 - 2019
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health
    NHMRC A*STAR Joint Grants
    Open grant
  • 2016 - 2020
    Methods and software tool for complex trait analyses using multi-omics data
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    Genetics of DNA Methylation and Its Role in Disease Susecptibility
    NHMRC Career Development Fellowship
    Open grant
  • 2015 - 2018
    The importance of DNA methylation in response to environmental changes (ARC Discovery Project administered by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2012 - 2014
    Inheritance of DNA methylation state in humans
    NHMRC Project Grant
    Open grant

Availability

Dr Allan McRae is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Cell-free DNA methodology for diagnosis and monitoring progression in Motor Neurone Disease

    Principal Advisor

    Other advisors: Dr Fleur Garton

  • Doctor Philosophy

    Understanding cellular and molecular heterogeneity in endometriosis using multi-omics data

    Principal Advisor

    Other advisors: Professor Naomi Wray, Dr Sally Mortlock

  • Doctor Philosophy

    Novel methods and data integration to understand the causes of Amyotrophic Lateral Sclerosis

    Associate Advisor

    Other advisors: Dr Jian Zeng, Dr Fleur Garton

  • Doctor Philosophy

    Multi-Omic Analyses of a Clinical Trial Cohort of Young People at Ultra-High Risk for Psychosis

    Associate Advisor

    Other advisors: Dr Enda Byrne, Professor Naomi Wray

  • Doctor Philosophy

    Exploring the role of clinical, lifestyle, environmental and molecular factors in endometriosis risk

    Associate Advisor

    Other advisors: Dr Sally Mortlock

  • Doctor Philosophy

    Multiomics of common co-occurring conditions in autism spectrum disorder

    Associate Advisor

    Other advisors: Dr Yuanhao Yang, Honorary Professor Jake Gratten

  • Doctor Philosophy

    Investigating the molecular basis of motor neurone disease using cell-free DNA

    Associate Advisor

    Other advisors: Professor Mark Midwinter, Dr Fleur Garton

  • Doctor Philosophy

    Genetics of Neurodevelopmental Disorders and associated comorbidities

    Associate Advisor

    Other advisors: Dr Enda Byrne

  • Doctor Philosophy

    Cellular genomics of Parkinson's disease

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Honorary Professor Jake Gratten, Dr Yuanhao Yang

Completed supervision

Enquiries

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