Dr Allan McRae
Dr

Allan McRae

Email: 

Availability

Dr Allan McRae is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Edinburgh

Search Professor Allan McRae’s works on UQ eSpace

176 works between 2002 and 2025
All (176) Journal Article (163) Book Chapter (2) Conference Publication (10) Other Outputs (1)

41 - 60 of 176 works

2020

Journal Article

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

Stevenson, Anna J., McCartney, Daniel L., Hillary, Robert F., Campbell, Archie, Morris, Stewart W., Bermingham, Mairead L., Walker, Rosie M., Evans, Kathryn L., Boutin, Thibaud S., Hayward, Caroline, McRae, Allan F., McColl, Barry W., Spires-Jones, Tara L., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2020). Characterisation of an inflammation-related epigenetic score and its association with cognitive ability. Clinical Epigenetics, 12 (1) 113, 113. doi: 10.1186/s13148-020-00903-8

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

2020

Journal Article

Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

Hillary, Robert F., Trejo-Banos, Daniel, Kousathanas, Athanasios, McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Patxot, Marion, Ojavee, Sven Erik, Zhang, Qian, Liewald, David C., Ritchie, Craig W., Evans, Kathryn L., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J., Robinson, Matthew R. and Marioni, Riccardo E. (2020). Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Genome Medicine, 12 (1) 60, 60. doi: 10.1186/s13073-020-00754-1

Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

2020

Journal Article

Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

Wu, Yang, Qi, Ting, Wang, Huanwei, Zhang, Futao, Zheng, Zhili, Phillips-Cremins, Jennifer E., Deary, Ian J., McRae, Allan F., Wray, Naomi R., Zeng, Jian and Yang, Jian (2020). Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data. Nature Communications, 11 (1) 2061, 1-12. doi: 10.1038/s41467-020-15587-0

Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

2020

Journal Article

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

Vallerga, Costanza L., Zhang, Futao, Fowdar, Javed, McRae, Allan F., Qi, Ting, Nabais, Marta F., Zhang, Qian, Kassam, Irfahan, Henders, Anjali K., Wallace, Leanne, Montgomery, Grant, Chuang, Yu-Hsuan, Horvath, Steve, Ritz, Beate, Halliday, Glenda, Hickie, Ian, Kwok, John B., Pearson, John, Pitcher, Toni, Kennedy, Martin, Bentley, Steven R., Silburn, Peter A., Yang, Jian, Wray, Naomi R., Lewis, Simon J. G., Anderson, Tim, Dalrymple-Alford, John, Mellick, George D., Visscher, Peter M. and Gratten, Jacob (2020). Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease. Nature Communications, 11 (1) 1238, 1238. doi: 10.1038/s41467-020-15065-7

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

2020

Journal Article

Erratum: Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular psychiatry (2020) 25 3 (584-602))

Sønderby, Ida E., Gústafsson, Ómar, Doan, Nhat Trung, Hibar, Derrek P., Martin-Brevet, Sandra, Abdellaoui, Abdel, Ames, David, Amunts, Katrin, Andersson, Michael, Armstrong, Nicola J., Bernard, Manon, Blackburn, Nicholas, Blangero, John, Boomsma, Dorret I., Bralten, Janita, Brattbak, Hans-Richard, Brodaty, Henry, Brouwer, Rachel M., Bülow, Robin, Calhoun, Vince, Caspers, Svenja, Cavalleri, Gianpiero, Chen, Chi-Hua, Cichon, Sven, Ciufolini, Simone, Corvin, Aiden, Crespo-Facorro, Benedicto, Curran, Joanne E., Dale, Anders M. ... Andreassen, Ole A. (2020). Erratum: Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular psychiatry (2020) 25 3 (584-602)). Molecular Psychiatry, 25 (3), 692-695. doi: 10.1038/s41380-019-0358-8

Erratum: Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia (Molecular psychiatry (2020) 25 3 (584-602))

2020

Journal Article

Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A. E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A. J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth ... Wray, Naomi R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine, 5 (1) 10, 1-9. doi: 10.1038/s41525-020-0118-3

Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

2020

Journal Article

Progression and survival of patients with motor neuron disease relative to their fecal microbiota

Ngo, Shyuan T., Restuadi, Restuadi, McCrea, Allan F., Van Eijk, Ruben P., Garton, Fleur, Henderson, Robert D., Wray, Naomi R., McCombe, Pamela A. and Steyn, Frederik J. (2020). Progression and survival of patients with motor neuron disease relative to their fecal microbiota. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21 (7-8), 1-14. doi: 10.1080/21678421.2020.1772825

Progression and survival of patients with motor neuron disease relative to their fecal microbiota

2019

Journal Article

An epigenome-wide association study of sex-specific chronological ageing

McCartney, Daniel L., Zhang, Futao, Hillary, Robert F., Zhang, Qian, Stevenson, Anna J., Walker, Rosie M., Bermingham, Mairead L., Boutin, Thibaud, Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Hayward, Caroline, Evans, Kathryn L., Chandra, Tamir, Deary, Ian J., McIntosh, Andrew M., Yang, Jian, Visscher, Peter M., McRae, Allan F. and Marioni, Riccardo E. (2019). An epigenome-wide association study of sex-specific chronological ageing. Genome Medicine, 12 (1) 1, 1. doi: 10.1186/s13073-019-0693-z

An epigenome-wide association study of sex-specific chronological ageing

2019

Journal Article

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Jia, Tianye, Chu, Congying, Liu, Yun, van Dongen, Jenny, Papastergios, Evangelos, Armstrong, Nicola J., Bastin, Mark E., Carrillo-Roa, Tania, den Braber, Anouk, Harris, Mathew, Jansen, Rick, Liu, Jingyu, Luciano, Michelle, Ori, Anil P. S., Roiz Santiañez, Roberto, Ruggeri, Barbara, Sarkisyan, Daniil, Shin, Jean, Sungeun, Kim, Tordesillas Gutiérrez, Diana, van’t Ent, Dennis, Ames, David, Artiges, Eric, Bakalkin, Georgy, Banaschewski, Tobias, Bokde, Arun L. W., Brodaty, Henry, Bromberg, Uli, Brouwer, Rachel ... Desrivières, Sylvane (2019). Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. Molecular Psychiatry, 26 (8), 1-12. doi: 10.1038/s41380-019-0605-z

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

2019

Journal Article

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

Stevenson, Anna J., McCartney, Daniel L., Hillary, Robert F., Redmond, Paul, Taylor, Adele M., Zhang, Qian, McRae, Allan F., Spires-Jones, Tara L., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2019). Childhood intelligence attenuates the association between biological ageing and health outcomes in later life. Translational Psychiatry, 9 (1) 323, 323. doi: 10.1038/s41398-019-0657-5

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

2019

Journal Article

Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition

Van Der Meer, Dennis, Sønderby, Ida E., Kaufmann, Tobias, Walters, G. Bragi, Abdellaoui, Abdel, Ames, David, Amunts, Katrin, Andersson, Micael, Armstrong, Nicola J., Bernard, Manon, Blackburn, Nicholas B., Blangero, John, Boomsma, Dorret I., Brodaty, Henry, Brouwer, Rachel M., Bülow, Robin, Cahn, Wiepke, Calhoun, Vince D., Caspers, Svenja, Cavalleri, Gianpiero L., Ching, Christopher R. K., Cichon, Sven, Ciufolini, Simone, Corvin, Aiden, Crespo-Facorro, Benedicto, Curran, Joanne E., Dalvie, Shareefa, Dazzan, Paola, De Geus, Eco J. C. ... Andreassen, Ole A. (2019). Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition. JAMA Psychiatry, 77 (4), 1-11. doi: 10.1001/jamapsychiatry.2019.3779

Association of copy number variation of the 15q11.2 BP1-BP2 region with cortical and subcortical morphology and cognition

2019

Journal Article

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

Zhang, Qian, Vallerga, Costanza L., Walker, Rosie M., Lin, Tian, Henders, Anjali K., Montgomery, Grant W., He, Ji, Fan, Dongsheng, Fowdar, Javed, Kennedy, Martin, Pitcher, Toni, Pearson, John, Halliday, Glenda, Kwok, John B., Hickie, Ian, Lewis, Simon, Anderson, Tim, Silburn, Peter A., Mellick, George D., Harris, Sarah E., Redmond, Paul, Murray, Alison D., Porteous, David J., Haley, Christopher S., Evans, Kathryn L., McIntosh, Andrew M., Yang, Jian, Gratten, Jacob, Marioni, Riccardo E. ... Visscher, Peter M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11 (1) 54, 54. doi: 10.1186/s13073-019-0667-1

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

2019

Journal Article

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

Wang, Huanwei, Zhang, Futao, Zeng, Jian, Wu, Yang, Kemper, Kathryn E., Xue, Angli, Zhang, Min, Powell, Joseph E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2019). Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Science Advances, 5 (8) eaaw3538, 1-12. doi: 10.1126/sciadv.aaw3538

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

2019

Journal Article

Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936. Nature Communications, 10 (1) 3160, 3160. doi: 10.1038/s41467-019-11177-x

Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

2019

Journal Article

The effect of X-linked dosage compensation on complex trait variation

Sidorenko, Julia, Kassam, Irfahan, Kemper, Kathryn E., Zeng, Jian, Lloyd-Jones, Luke R., Montgomery, Grant W., Gibson, Greg, Metspalu, Andres, Esko, Tonu, Yang, Jian, McRae, Allan F. and Visscher, Peter M. (2019). The effect of X-linked dosage compensation on complex trait variation. Nature Communications, 10 (1) 3009, 3009. doi: 10.1038/s41467-019-10598-y

The effect of X-linked dosage compensation on complex trait variation

2019

Journal Article

Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study

Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G., Nyholt, Dale R., Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B., Wray, Naomi R., Brown, Matthew A., Suetani, Rachel, Giacomotto, Jean ... Mowry, Bryan J. (2019). Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study. JAMA Psychiatry, 76 (10), 1026-1034. doi: 10.1001/jamapsychiatry.2019.1335

Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study

2019

Journal Article

Correction: GWAS on family history of Alzheimer’s disease

Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2019). Correction: GWAS on family history of Alzheimer’s disease. Translational Psychiatry, 9 (1) 161, 161. doi: 10.1038/s41398-019-0498-2

Correction: GWAS on family history of Alzheimer’s disease

2019

Journal Article

Gut microbiota in ALS: possible role in pathogenesis?

McCombe, Pamela A., Henderson, Robert D., Lee, Aven, Lee, John D., Woodruff, Trent M., Restuadi, Restuadi, McRae, Allan, Wray, Naomi R., Ngo, Shyuan and Steyn, Frederik J. (2019). Gut microbiota in ALS: possible role in pathogenesis?. Expert Review of Neurotherapeutics, 19 (9), 1-21. doi: 10.1080/14737175.2019.1623026

Gut microbiota in ALS: possible role in pathogenesis?

2019

Journal Article

OSCA: a tool for omic-data-based complex trait analysis

Zhang, Futao, Chen, Wenhan, Zhu, Zhihong, Zhang, Qian, Nabais, Marta F., Qi, Ting, Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2019). OSCA: a tool for omic-data-based complex trait analysis. Genome Biology, 20 (1) 107, 107. doi: 10.1186/s13059-019-1718-z

OSCA: a tool for omic-data-based complex trait analysis

2019

Journal Article

Tissue-specific sex-differences in human gene expression

Kassam, Irfahan, Wu, Yang, Yang, Jian, Visscher, Peter M. and McRae, Allan F. (2019). Tissue-specific sex-differences in human gene expression. Human Molecular Genetics, 28 (17), 2976-2986. doi: 10.1093/hmg/ddz090

Tissue-specific sex-differences in human gene expression

Current funding

  • 2025 - 2027
    Proteomic Biomarkers for ALS Disease Prognosis and Progression Monitoring
    United States Congressionally Directed Medical Research Programs - Amyotrophic Lateral Sclerosis Research Program
    Open grant
  • 2024 - 2025
    SALSA Study with MND and Me Foundation
    The MND and ME Foundation
    Open grant
  • 2022 - 2025
    MAGNET - A multi-arm, adaptive, group-sequential trial network to evaluate drug efficacy in patients with Amyotrophic Lateral Sclerosis (ALS) (FightMND grant administered by NeuRA)
    Neuroscience Research Australia
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2022 - 2025
    Leveraging medical records to identify patients at risk of neurodegenerative disease (EU-JPND grant coordinated by Institut du Cerveau et de la Moelle épinière)
    Boosting Dementia Research Grants (PR4): European Union Joint Program on Neurodegenerative Disease Research (JPND) Call for Multinational Projects
    Open grant
  • 2020 - 2025
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Cure for MND Foundation - Translational Research Grants
    Open grant

Past funding

  • 2023 - 2024
    An Australian Sporadic ALS transcriptome resource
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2022 - 2025
    A high-throughput system to identify ALS risk genes from genome-wide association studies
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2020 - 2024
    Genomic Control of Human Complex Trait Variation
    ARC Future Fellowships
    Open grant
  • 2019 - 2020
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health (NHMRC A*STAR grant led by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2018 - 2021
    BRAIN-MEND: Biological Resource Analysis to identify new mechanisms and phenotypes in Neurodegenerative Diseases (NHMRC component of EU JPND application)
    NHMRC Boosting Dementia Research Grants
    Open grant
  • 2018 - 2019
    Disturbances of DNA regulation in obesity, and their relationships to metabolic health
    NHMRC A*STAR Joint Grants
    Open grant
  • 2016 - 2020
    Methods and software tool for complex trait analyses using multi-omics data
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    Genetics of DNA Methylation and Its Role in Disease Susecptibility
    NHMRC Career Development Fellowship
    Open grant
  • 2015 - 2018
    The importance of DNA methylation in response to environmental changes (ARC Discovery Project administered by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2012 - 2014
    Inheritance of DNA methylation state in humans
    NHMRC Project Grant
    Open grant

Availability

Dr Allan McRae is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Understanding cellular and molecular heterogeneity in endometriosis using multi-omics data

    Principal Advisor

    Other advisors: Professor Naomi Wray, Dr Sally Mortlock

  • Doctor Philosophy

    Cell-free DNA methodology for diagnosis and monitoring progression in Motor Neurone Disease

    Principal Advisor

    Other advisors: Dr Fleur Garton

  • Doctor Philosophy

    Novel methods and data integration to understand the causes of Amyotrophic Lateral Sclerosis

    Associate Advisor

    Other advisors: Dr Jian Zeng, Dr Fleur Garton

  • Doctor Philosophy

    Genetics of Neurodevelopmental Disorders and associated comorbidities

    Associate Advisor

    Other advisors: Dr Enda Byrne

  • Doctor Philosophy

    Exploring the role of clinical, lifestyle, environmental and molecular factors in endometriosis risk

    Associate Advisor

    Other advisors: Dr Sally Mortlock

  • Doctor Philosophy

    Multiomics of common co-occurring conditions in autism spectrum disorder

    Associate Advisor

    Other advisors: Dr Yuanhao Yang, Honorary Professor Jake Gratten

  • Doctor Philosophy

    Multi-Omic Analyses of a Clinical Trial Cohort of Young People at Ultra-High Risk for Psychosis

    Associate Advisor

    Other advisors: Dr Enda Byrne, Professor Naomi Wray

  • Doctor Philosophy

    Cellular genomics of Parkinson's disease

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Honorary Professor Jake Gratten, Dr Yuanhao Yang

Completed supervision

Enquiries

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