
Overview
Availability
- Dr Allan McRae is:
- Available for supervision
Qualifications
- Doctor of Philosophy, University of Edinburgh
Works
Search Professor Allan McRae’s works on UQ eSpace
2019
Other Outputs
An epigenome-wide association study of sex-specific chronological ageing
McCartney, Daniel L., Hillary, Robert F., Zhang, Qian, Stevenson, Anna J., Walker, Rosie M., Bermingham, Mairead L., Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Evans, Kathryn L., Chandra, Tamir, Deary, Ian J., McIntosh, Andrew M., Visscher, Peter M., McRae, Allan F. and Marioni, Riccardo E. (2019). An epigenome-wide association study of sex-specific chronological ageing. doi: 10.1101/606020
2019
Other Outputs
Childhood intelligence attenuates the association between biological ageing and health outcomes in later
Stevenson, Anna J., McCartney, Daniel L., Hillary, Robert F., Redmond, Paul, Taylor, Adele M., Zhang, Qian, McRae, Allan F., Spires-Jones, Tara L., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2019). Childhood intelligence attenuates the association between biological ageing and health outcomes in later. doi: 10.1101/588293
2019
Journal Article
Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases
Mortlock, Sally, Restuadi, Restuadi, Levien, Rupert, Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Zhu, Zhihong, Qi, Ting, Wu, Yang, Lukowski, Samuel W., Rogers, Peter A. W., Yang, Jian, McRae, Allan F., Fung, Jenny N. and Montgomery, Grant W. (2019). Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases. Clinical Epigenetics, 11 (1) 49, 49. doi: 10.1186/s13148-019-0648-7
2019
Journal Article
An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort
Hamilton, Olivia K. L., Zhang, Qian, McRae, Allan F., Walker, Rosie M., Morris, Stewart W., Redmond, Paul, Campbell, Archie, Murray, Alison D., Porteous, David J., Evans, Kathryn L., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2019). An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort. International Journal of Obesity, 43 (9), 1795-1802. doi: 10.1038/s41366-018-0262-3
2019
Other Outputs
Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936
Hillary, Robert F., McCartney, Daniel L., Harris, Sarah E., Stevenson, Anna J., Seeboth, Anne, Zhang, Qian, Liewald, David C., Evans, Kathryn L., Ritchie, Craig W., Tucker-Drob, Elliot M., Wray, Naomi R., McRae, Allan F., Visscher, Peter M., Deary, Ian J. and Marioni, Riccardo E. (2019). Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936. doi: 10.1101/558940
2019
Conference Publication
Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers
Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167
2019
Book Chapter
A Cache-based data movement infrastructure for on-demand scientific cloud computing
Abramson, David, Carroll, Jake, Jin, Chao, Mallon, Michael, van Iperen, Zane, Nguyen, Hoang, McRae, Allan and Ming, Liang (2019). A Cache-based data movement infrastructure for on-demand scientific cloud computing. Supercomputing frontiers. (pp. 38-56) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-18645-6_3
2019
Conference Publication
Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium
Mortlock, Sally, Fung, Jenny N., Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Lukowski, Samuel W., McKinnon, Brett D., Yang, Jian, McRae, Allan, Rogers, Peter A. W. and Montgomery, Grant W. (2019). Identifying Target Genes for Endometriosis through Integration of Genetic Effects on Transcription and Methylation in Human Endometrium. 66th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Paris, France, 12-16 March 2019. Thousand Oaks, CA, United States: Sage.
2018
Journal Article
Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing
Stevenson, Anna J., McCartney, Daniel L., Harris, Sarah E., Taylor, Adele M., Redmond, Paul, Starr, John M., Zhang, Qian, McRae, Allan F., Wray, Naomi R., Spires-Jones, Tara L., McColl, Barry W., McIntosh, Andrew M., Deary, Ian J. and Marioni, Riccardo E. (2018). Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing. Clinical Epigenetics, 10 (1) 159, 159. doi: 10.1186/s13148-018-0585-x
2018
Journal Article
Identification of 55,000 replicated DNA methylation QTL
McRae, Allan F., Marioni, Riccardo E., Shah, Sonia, Yang, Jian, Powell, Joseph E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Bowdler, Lisa, Painter, Jodie N., Murphy, Lee, Martin, Nicholas G., Starr, John M., Wray, Naomi R., Deary, Ian J., Visscher, Peter M. and Montgomery, Grant W. (2018). Identification of 55,000 replicated DNA methylation QTL. Scientific Reports, 8 (1) 17605, 17605. doi: 10.1038/s41598-018-35871-w
2018
Journal Article
Genotype effects contribute to variation in longitudinal methylome patterns in older people
Zhang, Qian, Marioni, Riccardo E., Robinson, Matthew R., Higham, Jon, Sproul, Duncan, Wray, Naomi R., Deary, Ian J., McRae, Allan F. and Visscher, Peter M. (2018). Genotype effects contribute to variation in longitudinal methylome patterns in older people. Genome Medicine, 10 (1) 75, 75. doi: 10.1186/s13073-018-0585-7
2018
Journal Article
Epigenetic prediction of complex traits and death
McCartney, Daniel L., Hillary, Robert F., Stevenson, Anna J., Ritchie, Stuart J., Walker, Rosie M., Zhang, Qian, Morris, Stewart W., Bermingham, Mairead L., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Gale, Catharine R., Porteous, David J., Haley, Chris S., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J. and Marioni, Riccardo E. (2018). Epigenetic prediction of complex traits and death. Genome Biology, 19 (1) 136, 136. doi: 10.1186/s13059-018-1514-1
2018
Other Outputs
Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing
Stevenson, Anna J, McCartney, Daniel L, Harris, Sarah E, Taylor, Adele M, Redmond, Paul, Starr, John M, Zhang, Qian, McRae, Allan F, Wray, Naomi R, Spires-Jones, Tara L, McColl, Barry W, McIntosh, Andrew M, Deary, Ian J and Marioni, Riccardo E (2018). Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing. doi: 10.1101/397877
2018
Journal Article
Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome
Fung, Jenny N., Mortlock, Sally, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Zhu, Zhihong, Lukowski, Samuel W., McKinnon, Brett D., McRae, Allan, Yang, Jian, Healey, Martin, Powell, Joseph E., Rogers, Peter A. W. and Montgomery, Grant W (2018). Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome. Scientific Reports, 8 (1) 11424, 11424. doi: 10.1038/s41598-018-29462-y
2018
Journal Article
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Xue, Angli, Wu, Yang, Zhu, Zhihong, Zhang, Futao, Kemper, Kathryn E., Zheng, Zhili, Yengo, Loic, Lloyd-Jones, Luke R., Sidorenko, Julia, Wu, Yeda, eQTLGen Consortium, McRae, Allan F., Visscher, Peter M., Zeng, Jian and Yang, Jian (2018). Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications, 9 (1) 2941, 2941. doi: 10.1038/s41467-018-04951-w
2018
Journal Article
DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies
Story Jovanova, Olivera, Nedeljkovic, Ivana, Derek, Spieler, Walker, Rosie M., Liu, Chunyu, Luciano, Michelle, Bressler, Jan, Brody, Jennifer, Drake, Amanda J., Evans, Kathryn L., Gondalia, Rahul, Kunze, Sonja, Kuhnel, Brigitte, Lahti, Jari, Lemaitre, Rozenn N., Marioni, Riccardo E., Swenson, Brenton, Himali, Jayandra Jung, Wu, Hongsheng, Li, Yun, McRae, Allan F., Russ, Tom C., Stewart, James, Wang, Zhiying, Zhang, Guosheng, Ladwig, Karl-Heinz, Uitterlinden, Andre G., Guo, Xiuqing, Peters, Annette ... Amin, Najaf (2018). DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies. JAMA Psychiatry, 75 (9), 949-959. doi: 10.1001/jamapsychiatry.2018.1725
2018
Journal Article
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, eQTLGen Consortium, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2018). Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications, 9 (1) 2282, 2282. doi: 10.1038/s41467-018-04558-1
2018
Journal Article
Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans
Cuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M., Gaunt, Tom R., McRae, Allan, Visscher, Peter M., Montgomery, Grant W., Martin, Nicholas G., Hemani, Gibran, Suderman, Matthew, Relton, Caroline L., Davey Smith, George and Evans, David M. (2018). Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans. Human Molecular Genetics, 27 (16), 2927-2939. doi: 10.1093/hmg/ddy206
2018
Journal Article
GWAS on family history of Alzheimer's disease
Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2018). GWAS on family history of Alzheimer's disease. Translational Psychiatry, 8 (1) 99, 99. doi: 10.1038/s41398-018-0150-6
2018
Journal Article
Signatures of negative selection in the genetic architecture of human complex traits
Zeng, Jian, de Vlaming, Ronald, Wu, Yang, Robinson, Matthew R., Lloyd-Jones, Luke R., Yengo, Loic, Yap, Chloe X., Xue, Angli, Sidorenko, Julia, McRae, Allan F., Powell, Joseph E., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Gibson, Greg, Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2018). Signatures of negative selection in the genetic architecture of human complex traits. Nature Genetics, 50 (5), 746-753. doi: 10.1038/s41588-018-0101-4
Funding
Current funding
Supervision
Availability
- Dr Allan McRae is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Cell-free DNA methodology for diagnosis and monitoring progression in Motor Neurone Disease
Principal Advisor
Other advisors: Dr Fleur Garton
-
Doctor Philosophy
Understanding cellular and molecular heterogeneity in endometriosis using multi-omics data
Principal Advisor
Other advisors: Professor Naomi Wray, Dr Sally Mortlock
-
Doctor Philosophy
Novel methods and data integration to understand the causes of Amyotrophic Lateral Sclerosis
Associate Advisor
Other advisors: Dr Jian Zeng, Dr Fleur Garton
-
Doctor Philosophy
Multi-Omic Analyses of a Clinical Trial Cohort of Young People at Ultra-High Risk for Psychosis
Associate Advisor
Other advisors: Dr Enda Byrne, Professor Naomi Wray
-
Doctor Philosophy
Exploring the role of clinical, lifestyle, environmental and molecular factors in endometriosis risk
Associate Advisor
Other advisors: Dr Sally Mortlock
-
Doctor Philosophy
Multiomics of common co-occurring conditions in autism spectrum disorder
Associate Advisor
Other advisors: Dr Yuanhao Yang, Honorary Professor Jake Gratten
-
Doctor Philosophy
Investigating the molecular basis of motor neurone disease using cell-free DNA
Associate Advisor
Other advisors: Professor Mark Midwinter, Dr Fleur Garton
-
Doctor Philosophy
Genetics of Neurodevelopmental Disorders and associated comorbidities
Associate Advisor
Other advisors: Dr Enda Byrne
-
Doctor Philosophy
Cellular genomics of Parkinson's disease
Associate Advisor
Other advisors: Dr Quan Nguyen, Honorary Professor Jake Gratten, Dr Yuanhao Yang
Completed supervision
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Principal Advisor
Other advisors: Professor Peter Visscher
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Principal Advisor
Other advisors: Professor Peter Visscher
-
2022
Doctor Philosophy
Systems biology of motor neurone disease
Principal Advisor
Other advisors: Associate Professor Shyuan Ngo, Professor Naomi Wray
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Principal Advisor
Other advisors: Professor Peter Visscher, Professor Naomi Wray
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Principal Advisor
Other advisors: Professor Peter Visscher
-
2022
Doctor Philosophy
Studying the effects of DNA methylation variation across neurodegenerative disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Understanding the genetic and environmental variations in human complex traits
Associate Advisor
-
2021
Doctor Philosophy
A Complex Trait Genomics Approach to Investigating Amyotrophic Lateral Sclerosis
Associate Advisor
Other advisors: Professor Naomi Wray
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Associate Advisor
Other advisors: Professor Peter Visscher
-
2018
Master Philosophy
Integrating genome-wide association study data with gene expression to understand complex traits and common diseases
Associate Advisor
Other advisors: Professor Naomi Wray, Honorary Professor Jake Gratten
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Associate Advisor
Other advisors: Professor Peter Visscher
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