Overview
Background
Professor Antje Blumenthal combines her expertise in immunology and microbiology to lead research on molecular mechanisms that control immune responses to infection, alongside more recently developed research on new antimicrobials. The overall goal of her research is to improve our ability to treat severe bacterial infections as part of the global efforts to overcome the threat posed by antibiotic-resistant bacteria. Prof Blumenthal graduated with a major in Microbiology from the Christian-Albrechts-University in Kiel, Germany, pursued PhD research in Immunology at the Leibniz Research Center for Medicine and Biosciences Borstel, Germany, and undertook postdoctoral training at Weill Cornell Medical College, New York, USA. She joined The University of Queensland Diamantina Institute in 2010 where she leads the Infection & Inflammation Group, fostering cross-disciplinary collaborations with immunologists, microbiologists, chemists, clinical research teams and industry partners. Her research is enabled by major funding from international and national agencies, and has been recognised internationally and nationally by prestigious awards, speaking invitations at eminent conferences and institutions, invitations to peer-review for esteemed journals and funding agencies. Prof Blumenthal is an enthusiastic undergraduate teacher and research student advisor. She is proactive in advancing the careers of junior scientists, leads the development and implementation of initiatives that promote equity, diversity and inclusion in science, and a positive workplace culture. Through leadership roles within the University and professional societies as well as editorial roles for international journals, Prof Blumenthal actively contributes to the scientific community.
Availability
- Professor Antje Blumenthal is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Basic and Applied Immunology, University of Lübeck
Research interests
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Tuberculosis
- immune response - pathogenesis - novel anti-TB drugs
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Innate Immunity
molecular and cellular mechanisms of pathogen recognition, host cell activation and anti-microbial defence
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Macrophage biology
infection and inflammation related macrophage functions
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Inflammation
molecular regulation of inflammatory responses
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Sepsis
immune responses and biomarker discovery
Works
Search Professor Antje Blumenthal’s works on UQ eSpace
2001
Journal Article
Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity
Reiling, N., Blumenthal, A., Flad, H. D., Ernst, M. and Ehlers, S. (2001). Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity. Journal of Immunology, 167 (6), 3339-3345. doi: 10.4049/jimmunol.167.6.3339
2000
Conference Publication
Infection of human monocyte-derived macrophages with Mycobacterium avium: MAP kinase activation is inversely correlated to bacterial survival in vitro
Blumenthal, A., Ehlers, S., Ernst, M., Flad, H.-D. and Reiling, N. (2000). Infection of human monocyte-derived macrophages with Mycobacterium avium: MAP kinase activation is inversely correlated to bacterial survival in vitro. Joint Annual Meeting of the German and Dutch Societies of Immunology, Duseldorf, Germany, 29 November - 02 December 2000. Jena, Germany: Urban und Fischer Verlag.
2000
Conference Publication
Mycobacteria-induced TNF and IL-10 formation by human macrophages: the role of MAP kinases
Reiling, N., Blumenthal, A., Flad, H.-D., Ernst, M. and Ehlers, S. (2000). Mycobacteria-induced TNF and IL-10 formation by human macrophages: the role of MAP kinases. Joint Annual Meeting of the German and Dutch Societies of Immunology, Duseldorf, Germany, 29 November - 02 December 2000. Jena, Germany: Urban und Fischer Verlag.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Antje Blumenthal is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Molecular regulators of macrophage functions during Mycobacterium tuberculosis infection
Principal Advisor
Other advisors: Dr Carmen Mathmann
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Doctor Philosophy
Impact of nitric oxide on inflammation and coagulation in patients undergoing extracorporeal membrane oxygenation (ECMO)
Principal Advisor
Other advisors: Professor Craig McBride
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Doctor Philosophy
Mapping cellular signalling pathways in mycobacteria-infected macrophages
Principal Advisor
Other advisors: Dr Tom Schultz, Dr Carmen Mathmann
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Doctor Philosophy
Transmission dynamics of multi-drug resistant tuberculosis amongst immune suppressed patients exposed to an infectious case
Associate Advisor
Other advisors: Honorary Professor John Upham, Professor Rachel Thomson
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Doctor Philosophy
Functions of CSF1R signalling in inflammation.
Associate Advisor
Other advisors: Professor David Hume, Dr Katharine Irvine
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Doctor Philosophy
The Gut-Lung axis in Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)
Associate Advisor
Other advisors: Professor Mark Morrison, Professor Rachel Thomson
Completed supervision
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2024
Doctor Philosophy
Characterisation of the anti-mycobacterial activity of wollamide cyclic hexapeptides against Mycobacterium tuberculo sis
Principal Advisor
Other advisors: Associate Professor Timothy Wells
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2024
Doctor Philosophy
Investigating molecular mechanisms of RP105-dependent macrophage activation during mycobacterial infection
Principal Advisor
Other advisors: Professor Matt Sweet, Dr Tom Schultz
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2023
Doctor Philosophy
Immune functions of WNT production and signalling in the host response to infection with pathogenic E. coli.
Principal Advisor
Other advisors: Associate Professor Timothy Wells, Dr Janin Chandra
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2023
Doctor Philosophy
Innate immune mechanisms that shape inflammatory and antimicrobial responses during mycobacterial infection
Principal Advisor
Other advisors: Professor Matt Sweet
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2023
Doctor Philosophy
Bacteria-induced WNT responses and their role in infection-associated inflammation
Principal Advisor
Other advisors: Associate Professor Jeremy Cohen
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2019
Doctor Philosophy
Investigation of Wnt pathway inhibition on host cell control of Listeria monocytogenes infection
Principal Advisor
Other advisors: Associate Professor Jakob Begun
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2018
Doctor Philosophy
Characterisation of the molecular mechanisms of RP105-dependent macrophage activation
Principal Advisor
Other advisors: Professor Matt Sweet
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2015
Doctor Philosophy
Characterisation of RP105's divergent functions in macrophage responses to mycobacteria and LPS
Principal Advisor
Other advisors: Emeritus Professor Ian Frazer
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2015
Doctor Philosophy
Contributions of Wnt signalling to immune responses during acute bacterial infection
Principal Advisor
Other advisors: Emeritus Professor Ian Frazer
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2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Associate Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Kiarash Khosrotehrani
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2020
Doctor Philosophy
Regulation of responses to therapeutic antibodies by macrophages derived from chronic lymphocytic leukaemia patients
Associate Advisor
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2014
Doctor Philosophy
Mechanisms of immunoregulation in human papillomavirus-associated epithelial hyperplasia: of mice and (wo)men
Associate Advisor
Other advisors: Emeritus Professor Ian Frazer
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2014
Doctor Philosophy
The development of an RNAi therapy against acute respiratory viral infection
Associate Advisor
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2013
Doctor Philosophy
Dissecting the role of Mincle in the macrophage response to trehalose-6,6'-dimycolate and mycobacteria.
Associate Advisor
Media
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