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2023 Conference Publication High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLLSabdia, Muhammed B., Burgess, Melinda, Law, Soi Cheng, Thurgood, Lauren A., Kazakoff, Stephen, Swain, Fiona, Tobin, Joshua W.D., Mollee, Peter, Patch, Ann-Marie and Gandhi, Maher K (2023). High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-174149 |
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2023 Conference Publication Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trialTobin, J. W., Jurinovic, V., Tsang, H., Roos, D., Tsang, R., Macann, A., Davis, S., Christie, D., Law, S., Nath, K., Sabdia, M., Patch, A. M., Gunawardana, J., Merida de Long, L., Hoster, E., Horn, H., Shanavas, M., Li, L., Cheah, C., Benhur, A., Hou, M., O'Brien, P., Johnston, A. M., Cochrane, T., Butler, J., Thompson, E., Blombery, P., Seymour, J. F., Gandhi, M. K. and MacManus, M. (2023). Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13-17 June 2023. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.3163_140 |
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2023 Conference Publication Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphomaTobin, J. W., Tsang, H., Patch, A., Keane, C., Law, S. C., Gunawardana, J., Blombery, P., Thompson, E. R., Sabdia, M. B., De Long, L. M., Nath, K., Kazakoff, S. H., Cheah, C., Amanuel, B., Cochrane, T., Butler, J., Johnston, A., Shanavas, M., Li, L., Shelton, V., Hershenfeld, S., Kridel, R., Seymour, J. F., MacManus, M. and Gandhi, M. K. (2023). Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_189 |
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2022 Conference Publication Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin LymphomaGunawardana, Jay, Law, Soi C., Sabdia, Muhammed B., Bednarska, Karolina, Brosda, Sandra, Zaharia, Andreea, Tsang, Hennes, de Long, Lilia M., Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Gould, Clare, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher K. (2022). Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma. Third AACR International Meeting: Advances in Malignant Lymphoma: Maximizing the Basic-Translational Interface for Clinical Application, 23-25 June 2022, Boston, MA USA. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/2643-3249.lymphoma22-a17 |
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2021 Conference Publication The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin LymphomaGunawardana, Jay, Sabdia, Muhammed B., Bednarska, Karolina, Law, Soi C., Brosda, Sandra, Tsang, Hennes, De Long, Lilia Merida, Zaharia, Andreea, Lee, Justina, Jude, Emily, Hawkes, Eliza, Nath, Karthik, Gould, Clare, Burgess, Melinda Lea, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Talaulikar, Dipti, Jain, Sanjiv, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher (2021). The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin Lymphoma. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-145840 |
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2020 Conference Publication Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphomaTsang, Hennes, Patch, Ann-Marie, Keane, Colm, Law, Soi C., Gunawardana, Jay, Blombery, Piers, Thompson, Ella R., Sabdia, Muhammed B., De Long, Lilia Merida, Belle, Clemence J., Nath, Karthik, Tobin, Joshua W.D., Kazakoff, Stephen H., Seymour, John F., MacManus, Michael and Gandhi, Maher K. (2020). Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma. 62nd ASH Annual Meeting and Exposition, Online, 5-8 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2020-135954 |
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2019 Conference Publication Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockadeNath, Karthik, Law, Soi C., Sabdia, Muhammed B., De Long, Lilia Merida, Shanavas, Mohamed, Tobin, Joshua W. D., Gunawardana, Jay, Vari, Frank, Halliday, Sarah-Jane, Hernandez, Annette, Cross, Donna, Bird, Robert J., Keane, Colm and Gandhi, Maher K. (2019). Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7 - 10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-130050 |
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2019 Conference Publication EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapyGandhi, M.K., Hoang, T., Tobin, J.W., Law, S.C., Talaulikar, D., Jain, S., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Casey, J., Wight, J., Hawkes, E. and Keane, C. (2019). EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy. 15th International Conference on Malignant Lymphoma, Lugano, Switzerland, 18–22 June 2019. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.91_2629 |
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2018 Conference Publication A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trialAbro, Emad Uddin, Law, Soi C., Keane, Colm, Birch, Simone, Sabdia, Muhammed Bilal, Tobin, Joshua W. D., Johnson, Peter, Trotman, Judith, Berkahn, Leanne, Fulham, Michael, Anderson, Richard A., Saunderson, Anne L., Gunawardana, Jay, Cross, Donna, Hernandez, Annette, Halliday, Sarah-Jane, Bird, Robert, Law, W. P., Gill, Devinder and Gandhi, Maher K. (2018). A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial. 60th ASH Annual Meeting, San Diego, CA United States, 1-4 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-112008 |
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2018 Conference Publication Elevated LAG-3 111,xpression in the Tumor Microenvironement of Patients with DLBCL Is Associated with a Non-GCB Phenotype and Poor PrognosisKeane, Colm, Law, Soi C., Gould, Clare, Francis, Santiyagu, Abro, Emad Uddin, Tobin, Joshua W. D., Birch, Simone, Gifford, Grace, Gabreilli, Sara, Stevenson, William S., Talaulikar, Dipti, Gill, Anthony, Jain, Sanjiv, Cross, Donna, Hernadez, Annette, Halliday, Sarah-Jane, Bird, Robert, Hertzberg, Mark and Gandhi, Maher K. (2018). Elevated LAG-3 111,xpression in the Tumor Microenvironement of Patients with DLBCL Is Associated with a Non-GCB Phenotype and Poor Prognosis. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego, CA, United States, 1-4 December 2018. Washington, DC, Untied States: American Society of Hematology. doi: 10.1182/blood-2018-99-112830 |
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2018 Conference Publication The Tumor Microenvironment of Nodular Lymphocyte Predominant Hodgkin Lymphoma Is a Unique Immunobiological Entity Distinct from Classical Hodgkin LymphomaGunawardana, Jay, Bednarska, Karolina, Law, Soi C., Lee, Justina, Sabdia, Muhammed Bilal, Tobin, Joshua W. D., Birch, Simone, Keane, Colm and Gandhi, Maher K. (2018). The Tumor Microenvironment of Nodular Lymphocyte Predominant Hodgkin Lymphoma Is a Unique Immunobiological Entity Distinct from Classical Hodgkin Lymphoma. 60th Annual Meeting of the American-Society-of-Hematology (ASH), San Diego CA, United States, 1-4 December 2018. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-115836 |
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2018 Conference Publication Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis preventionWehr, Pascale, Nel, Hendrik, Law, Soi Cheng, Jansen, Diahann, La Gruta, Nicole, Reid, Hugh, Rossjohn, Jamie and Thomas, Ranjeny (2018). Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention. 2018 ACR/ARHP Annual Meeting, Chicago, Il United States, 19-24 October 2018. Hoboken, NJ United States: John Wiley & Sons. |
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2017 Conference Publication Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritisJansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Koppejan, Hester, Hameetman, Marjolijn, Liu, Ligong, Corbett, Alexandra, Eckle, Sidonia, Fairlie, David, Toes, Rene E. M., van Gaalen, Floris, Rossjohn, Jamie, McCluskey, James and Thomas, Ranjeny (2017). Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis. 2017 ACR/ARHP Annual Meeting, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons. |
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2016 Conference Publication Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing SpondylitisJansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Benham, Helen, Cummins, Lisa, Brown, Matthew, Kenna, Tony, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Morrison, Mark, Thomas, Ranjeny, Cuiv, Paraic O., McCluskey, James and Corbett, Alexandra (2016). Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis. 2016 ACR/ARHP Annual Meeting, Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.39977 |
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2016 Conference Publication Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritisScally, S., Law, S. -C, van Heemst, J., Wieles, D., Moustakis, A., Papadopoulos, G., van der Woude, D., Hitchon, C., Robinson, D., Huizinga, T., Reid, H., Toes, R., El-Gabalawy, H., Rossjohn, J. and Thomas, R. (2016). Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patientsLaw, S. C., Nel, H. J., Scally, S. W., Mehdi, A., Le Cao, K. -A, Rossjohn, J., Reid, H. H., La Gruta, N. L. and Thomas, R. (2016). Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2015 Conference Publication The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoirevan Heemst, Jurgen, Scally, Stephen, Law, Soi Cheng, van der Woude, Diane, Hitchon, Carol, Robinson, David B., Huizinga, T. W. J., Reid, Hugh H., Toes, Rene E. M., El-Gabalawy, Hani, Rossjohn, Jamie and Thomas, Ranjeny (2015). The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL. |
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2015 Conference Publication Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) PatientsLaw, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL. |
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2015 Conference Publication Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell LevelLaw, S., Rossjohn, J., Nel, H., La Gruta, N., Reid, H. and Thomas, R. (2015). Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level. Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, Adelaide, South Australia, 23–26 May 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12752 |
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2014 Conference Publication Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, 14-19 November 2014. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/art.38914 |
