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2016 Journal Article Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid SynthaseLonhienne, Thierry, Nouwens, Amanda, Williams, Craig M., Fraser, James A., Lee, Yu-Ting, West, Nicholas P. and Guddat, Luke W. (2016). Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase. Angewandte Chemie - International Edition, 55 (13), 4247-4251. doi: 10.1002/anie.201511985 |
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2015 Journal Article Naked-eye colorimetric and electrochemical detection of Mycobacterium tuberculosis—toward rapid screening for active case findingNg, Benjamin Y. C., Wee, Eugene J. H., West, Nicholas P. and Trau, Matt (2015). Naked-eye colorimetric and electrochemical detection of Mycobacterium tuberculosis—toward rapid screening for active case finding. ACS Sensors, 1 (2), 173-178. doi: 10.1021/acssensors.5b00171 |
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2015 Journal Article Rapid, Single-Cell Electrochemical Detection of Mycobacterium tuberculosis Using Colloidal Gold NanoparticlesNg, Benjamin Y. C., Xiao, Wei, West, Nicholas P., Wee, Eugene J. H., Wang, Yuling and Trau, Matt (2015). Rapid, Single-Cell Electrochemical Detection of Mycobacterium tuberculosis Using Colloidal Gold Nanoparticles. Analytical Chemistry, 87 (20), 10613-10618. doi: 10.1021/acs.analchem.5b03121 |
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2015 Journal Article Rapid DNA detection of Mycobacterium tuberculosis-towards single cell sensitivity in point-of-care diagnosisNg, Benjamin Y.C., Wee, Eugene J. H., West, Nicholas P. and Trau, Matt (2015). Rapid DNA detection of Mycobacterium tuberculosis-towards single cell sensitivity in point-of-care diagnosis. Scientific Reports, 5 (1) 15027, 15027.1-15027.7. doi: 10.1038/srep15027 |
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2015 Journal Article Host-pathogen interaction during bacterial vaccinationBarnett, Timothy C., Lim, Jin Yan, Soderholm, Amelia T., Rivera-Hernandez, Tania, West, Nicholas P. and Walker, Mark J. (2015). Host-pathogen interaction during bacterial vaccination. Current Opinion in Immunology, 36, 1-7. doi: 10.1016/j.coi.2015.04.002 |
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2015 Journal Article First crystal structures of mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase: complexes with GMP and pyrophosphate and with acyclic nucleoside phosphonates ehose prodrugs have antituberculosis activityEng, Wai Soon, Hockova, Dana, Spacek, Petr, Janeba, Zlatko, West, Nicholas P., Woods, Kyra, Naesens, Lieve M. J., Keough, Dianne T. and Guddat, Luke W. (2015). First crystal structures of mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase: complexes with GMP and pyrophosphate and with acyclic nucleoside phosphonates ehose prodrugs have antituberculosis activity. Journal of Medicinal Chemistry, 58 (11), 4822-4838. doi: 10.1021/acs.jmedchem.5b00611 |
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2015 Journal Article Manganese homeostasis in group A Streptococcus is critical for resistance to oxidative stress and virulenceTurner, Andrew G., Ong, Cheryl-lynn, Gillen, Christine M., Davies, Mark R., West, Nicholas P., McEwan, Alastair G. and Walker, Mark J. (2015). Manganese homeostasis in group A Streptococcus is critical for resistance to oxidative stress and virulence. mBio, 6 (2) e00278-15, 1-10. doi: 10.1128/mBio.00278-15 |
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2014 Journal Article The contribution of non-human primate models to the development of human vaccinesRivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322. |
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2014 Journal Article ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamicsMarteyn, Benoit S., Karimova, Gouzel, Fenton, Andrew K., Gazi, Anastasia D., West, Nicholas, Touqui, Lhousseine, Prevost, Marie-Christine, Betton, Jean-Michel, Poyraz, Oemer, Ladant, Daniel, Gerdes, Kenn, Sansonetti, Philippe J. and Tang, Christoph M. (2014). ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics. mBio, 5 (2) e00022-14. doi: 10.1128/mBio.00022-14 |
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2014 Journal Article Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killingLy, Diane, Taylor, Jude M., Tsatsaronis, James A., Monteleone, Mercedes M., Skora, Amanda S., Donald, Cortny A., Maddocks, Tracy, Nizet, Victor, West, Nicholas P., Ranson, Marie, Walker, Mark J., McArthur, Jason D. and Sanderson-Smith, Martina L. (2014). Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. Journal of Innate Immunity, 6 (2), 240-250. doi: 10.1159/000353754 |
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2013 Journal Article Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1- phosphate uridyltransferase (GlmU)Tran, A. T., Wen, D., West, N. P., Baker, E. N., Britton, W. J. and Payne, R. J. (2013). Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1- phosphate uridyltransferase (GlmU). Organic and Biomolecular Chemistry, 11 (46), 8113-8126. doi: 10.1039/c3ob41896k |
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2013 Journal Article TLR2-targeted secreted proteins from Mycobacterium tuberculosis are protective as powdered pulmonary vaccinesTyne, Anneliese S., Chan, John Gar Yan, Shanahan, Erin R., Atmosukarto, Ines, Chan, Hak-Kim, Britton, Warwick J. and West, Nicholas P. (2013). TLR2-targeted secreted proteins from Mycobacterium tuberculosis are protective as powdered pulmonary vaccines. Vaccine, 31 (40), 4322-4329. doi: 10.1016/j.vaccine.2013.07.022 |
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2013 Journal Article Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agentsKeough, Dianne T., Hocková, Dana, Rejman, Dominik, Spaček, Petr, Vrbková, Silvie, Krečmerová, Marcela, Eng, Wai Soon, Jans, Harmen, West, Nicholas P., Naesens, Lieve M. J., de Jersey, John and Guddat, Luke W. (2013). Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agents. Journal of Medicinal Chemistry, 56 (17), 6967-6984. doi: 10.1021/jm400779n |
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2013 Journal Article Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosisPinto, Rachel, Leotta, Lisa, Shanahan, Erin R., West, Nicholas P., Leyh, Thomas S., Britton, Warwick and Triccas, James A. (2013). Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis. Journal of Infectious Diseases, 207 (5), 778-785. doi: 10.1093/infdis/jis751 |
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2012 Journal Article Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration StrategyAnh Thu Tran, West, Nicholas P., Britton, Warwick J. and Payne, Richard J. (2012). Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy. Chemmedchem, 7 (6), 1031-1043. doi: 10.1002/cmdc.201100606 |
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2012 Journal Article The Secreted Lipoprotein, MPT83, of Mycobacterium tuberculosis Is Recognized during Human Tuberculosis and Stimulates Protective Immunity in MiceKao, Fan F., Mahmuda, Sultana, Pinto, Rachel, Triccas, James A., West, Nicholas P. and Britton, Warwick J. (2012). The Secreted Lipoprotein, MPT83, of Mycobacterium tuberculosis Is Recognized during Human Tuberculosis and Stimulates Protective Immunity in Mice. PLoS One, 7 (5) e34991, e34991. doi: 10.1371/journal.pone.0034991 |
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2012 Journal Article Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active siteManos-Turvey, Alexandra, Cergol, Katie M., Salam, Noeris K., Bulloch, Esther M. M., Chi, Gamma, Pang, Angel, Britton, Warwick J., West, Nicholas P., Baker, Edward N., Lott, J. Shaun and Payne, Richard J. (2012). Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site. Organic and Biomolecular Chemistry, 10 (46), 9223-9236. doi: 10.1039/c2ob26736e |
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2011 Journal Article Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosisWest, Nicholas P., Thomson, Scott A., Triccas, James A., Medveczky, C. Jill, Ramshaw, Ian A. and Britton, Warwick J. (2011). Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosis. Vaccine, 29 (44), 7759-7765. doi: 10.1016/j.vaccine.2011.07.109 |
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2011 Journal Article Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug LeadsAnh Thu Tran, Cergol, Katie M., West, Nicholas P., Randall, Elizabeth J., Britton, Warwick J., Bokhari, Syed Ali Imran, Ibrahim, Musadiq, Lapthorn, Adrian J. and Payne, Richard J. (2011). Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug Leads. Chemmedchem, 6 (2), 262-265. doi: 10.1002/cmdc.201000399 |
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2011 Journal Article Immunity to mycobacterium tuberculosisTriccas, James A., Winter, Nathalie, Feng, Carl G. and West, Nicholas P. (2011). Immunity to mycobacterium tuberculosis. Clinical & Developmental Immunology, 2011 (406549) 406549, 1-2. doi: 10.1155/2011/406549 |
