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2022

Conference Publication

A Novel Role for Glucocerebrosidase 1 (GBA1) in Parkinson's Disease

Jayabalan, Nanthini, Roper, Katherine Kerry, Woodhouse, Helen M., Adam, Robert J., O'Sullivan, John D. and Gordon, Richard (2022). A Novel Role for Glucocerebrosidase 1 (GBA1) in Parkinson's Disease. Experimental Biology Meeting 2022, Philadelphia, PA United States, 2-5 April 2022. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1096/fasebj.2022.36.S1.R5391

A Novel Role for Glucocerebrosidase 1 (GBA1) in Parkinson's Disease

2022

Conference Publication

LC-MS based urine metabolomic profiling indicate altered gut microbiome and host lipid metabolites in Parkinson's disease

Jewell, Shannon, Roper, Kerry, Woodhouse, Helen, Adam, Robert, O'Sullivan, John and Gordon, Richard (2022). LC-MS based urine metabolomic profiling indicate altered gut microbiome and host lipid metabolites in Parkinson's disease. Experimental Biology 2022 Meeting, Philadelphia, PA United States, 2-5 April 2022. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1096/fasebj.2022.36.S1.R2928

LC-MS based urine metabolomic profiling indicate altered gut microbiome and host lipid metabolites in Parkinson's disease

2018

Conference Publication

C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation

Gordon, Richard, Albornoz, Eduardo, Kanthasamy, Anumantha and Woodruff, Trent (2018). C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation. 27th International Complement Workshop (ICW), Santa Fe, NM, United States, Sep 16-20, 2018. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2018.06.247

C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation

2017

Conference Publication

Motor neuron disease proteins activate complement and generate C5a

Deora, Vandana, Mantovani, Susanna, Yerbury, Justin, Clark, Richard, Atkin, Julie, Lee, John, Gordon, Richard and Woodruff, Trent M. (2017). Motor neuron disease proteins activate complement and generate C5a. 16th European Meeting on Complement in Human Disease (EMCHD), Copenhagen, Denmark, 8-12 September 2017. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2017.06.144

Motor neuron disease proteins activate complement and generate C5a

2017

Conference Publication

Gut microbiome changes induced by experimental trichuris muris infection are associated with decreased cognitive function in mice

Magalhaes, Ricardo J. Soares, Giacomin, Paul, Sarnyay, Zoltan, Kraeuter, Ann, Urich, Tim, Bengtsson, Mia, Jin, Shuting, Albornoz, Eduardo A., Gordon, Richard and Woodruff, Trent (2017). Gut microbiome changes induced by experimental trichuris muris infection are associated with decreased cognitive function in mice. 65th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH), Atlanta, GA, United States, 13-16 November 2016. Deerfield, United States: American Society of Tropical Medicine and Hygiene.

Gut microbiome changes induced by experimental trichuris muris infection are associated with decreased cognitive function in mice

2016

Conference Publication

A pathogenic role for the C5a receptor, C5aR2, in mouse models of Huntington's and Parkinson's disease

Li, Rui, Lee, John D., Levin, Samantha, Gordon, Richard and Woodruff, Trent M. (2016). A pathogenic role for the C5a receptor, C5aR2, in mouse models of Huntington's and Parkinson's disease. The XXVI International Complement Workshop (ICW), Kanazawa, Japan, 4-8 September 2016. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2016.06.186

A pathogenic role for the C5a receptor, C5aR2, in mouse models of Huntington's and Parkinson's disease

2016

Conference Publication

Complement C5a activates microglial NLRP3 inflammasomes and drives neurodegeneration in Parkinson's disease through C5aR1

Gordon, Richard, Albornoz, Eduardo A., Kumar, Vinod, Zhou, Kiane, Garin-Michaud, Ashoka, Mantavani, Susanna, Kanthasamy, Anumantha G. and Woodruff, Trent M. (2016). Complement C5a activates microglial NLRP3 inflammasomes and drives neurodegeneration in Parkinson's disease through C5aR1. The XXVI International Complement Workshop (ICW), Kanazawa, Japan, 4-8 September 2016. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2016.06.146

Complement C5a activates microglial NLRP3 inflammasomes and drives neurodegeneration in Parkinson's disease through C5aR1

2016

Conference Publication

The complement C5a receptor, C5aR2 contributes to motor deficits in mouse models of Huntington's and Parkinson's disease

Li, R., Levin, S., Lee, J., Gordon, R. and Woodruff, T. (2016). The complement C5a receptor, C5aR2 contributes to motor deficits in mouse models of Huntington's and Parkinson's disease. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200

The complement C5a receptor, C5aR2 contributes to motor deficits in mouse models of Huntington's and Parkinson's disease

2015

Conference Publication

Peripheral immune complement activation in neurodegenerative disease

Mantovani, S., Gordon, R., Ngo, S., Pfluger, C., O'Sullivan, J., Noakes, P., Henderson, R., McCombe, P. and Woodruff, T. (2015). Peripheral immune complement activation in neurodegenerative disease. 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/jnc.13188

Peripheral immune complement activation in neurodegenerative disease

2015

Conference Publication

Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway

Albornoz, E., Deora, V., Robertson, B. A., Cooper, M. A., Schroder, K., Woodruff, T. M. and Gordon, R. (2015). Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley-Blackwell.

Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway

2013

Conference Publication

Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease

Mantovani, S., Li, R., Gordon, R., Kumar, V., Taylor, S. and Woodruff, T. M. (2013). Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease. World Congress on Huntington’s disease, Rio de Janeiro, Brazil, 15-18 September 2013. Amsterdam, Netherlands: I O S Press.

Behavioural and pathological phenotyping of the C57BL/6J BACHD transgenic mouse model of Huntington’s disease