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2025

Journal Article

Nuclear magnetic resonance fingerprinting and principal component analysis strategies lead to anti-tuberculosis natural product discovery from actinomycetes

Han, Jianying, Liu, Xueting, Zhang, Lixin, Quinn, Ronald J. and Liu, Miaomiao (2025). Nuclear magnetic resonance fingerprinting and principal component analysis strategies lead to anti-tuberculosis natural product discovery from actinomycetes. Antibiotics, 14 (1) 108, 1-26. doi: 10.3390/antibiotics14010108

Nuclear magnetic resonance fingerprinting and principal component analysis strategies lead to anti-tuberculosis natural product discovery from actinomycetes

2024

Journal Article

Goondicones A–H: Spiro-isoindolinone heartworm anthelmintics from an Australian pasture-soil-derived Streptomyces sp.

Han, Jianying, Bruhn, David F., Childs, Cynthia T., Moreno, Yovany, Salim, Angela A., Wu, Taizong and Capon, Robert J. (2024). Goondicones A–H: Spiro-isoindolinone heartworm anthelmintics from an Australian pasture-soil-derived Streptomyces sp.. Antibiotics, 13 (12) 1222, 1222. doi: 10.3390/antibiotics13121222

Goondicones A–H: Spiro-isoindolinone heartworm anthelmintics from an Australian pasture-soil-derived Streptomyces sp.

2024

Journal Article

Goondomycins A–H: Carbocyclic ansa-Polyketides from an Australian pasture Streptomyces with selective activity against Dirofilaria immitis

Han, Jianying, Bruhn, David F., Roberts, Dana C., Burkman, Erica, Moreno, Yovany, Salim, Angela A. and Capon, Robert J. (2024). Goondomycins A–H: Carbocyclic ansa-Polyketides from an Australian pasture Streptomyces with selective activity against Dirofilaria immitis. Journal of Natural Products, 87 (12), 2810-2821. doi: 10.1021/acs.jnatprod.4c00987

Goondomycins A–H: Carbocyclic ansa-Polyketides from an Australian pasture Streptomyces with selective activity against Dirofilaria immitis

2024

Journal Article

Goondolinones A and B: Terpenyl-quinolin-4(1H)-ones from an Australian volcanic crater soil-derived Actinomadura sp., with selective activity against Dirofilaria immitis (Heartworm)

Han, Jianying, Bruhn, David F, Roberts, Dana C., Burkman, Erica J., Moreno, Yovany, Bernhardt, Paul V., Salim, Angela A. and Capon, Robert J. (2024). Goondolinones A and B: Terpenyl-quinolin-4(1H)-ones from an Australian volcanic crater soil-derived Actinomadura sp., with selective activity against Dirofilaria immitis (Heartworm). Journal of Natural Products, 87 (12), 2855-2862. doi: 10.1021/acs.jnatprod.4c01146

Goondolinones A and B: Terpenyl-quinolin-4(1H)-ones from an Australian volcanic crater soil-derived Actinomadura sp., with selective activity against Dirofilaria immitis (Heartworm)

2024

Journal Article

Rapid discovery of antimicrobial and antimalarial agents from natural product fragments

Han, Jianying, Liu, Xueting, Zhang, Lixin, Van Voorhis, Wesley C., Quinn, Ronald J. and Liu, Miaomiao (2024). Rapid discovery of antimicrobial and antimalarial agents from natural product fragments. Separations, 11 (7) 194. doi: 10.3390/separations11070194

Rapid discovery of antimicrobial and antimalarial agents from natural product fragments

2024

Journal Article

Goondansamycins A–H: Benzenoid Ansamycins from an Australian volcanic crater soil-derived Actinomadura sp. S4S-00069B08

Han, Jianying, Bernhardt, Paul V. and Capon, Robert J. (2024). Goondansamycins A–H: Benzenoid Ansamycins from an Australian volcanic crater soil-derived Actinomadura sp. S4S-00069B08. Journal of Natural Products, 87 (5), 1471-1478. doi: 10.1021/acs.jnatprod.4c00336

Goondansamycins A–H: Benzenoid Ansamycins from an Australian volcanic crater soil-derived Actinomadura sp. S4S-00069B08

2022

Journal Article

Anti-mycobacterial natural products and mechanisms of action

Han, Jianying, Liu, Xueting, Zhang, Lixin, Quinn, Ronald J. and Feng, Yunjiang (2022). Anti-mycobacterial natural products and mechanisms of action. Natural Product Reports, 39 (1), 77-89. doi: 10.1039/d1np00011j

Anti-mycobacterial natural products and mechanisms of action

2021

Journal Article

Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi

Jiang, Lan, Zhu, Guoliang, Han, Jianying, Hou, Chengjian, Zhang, Xue, Wang, Zhixin, Yuan, Weize, Lv, Kangjie, Cong, Zhanren, Wang, Xinye, Chen, Xiangyin, Karthik, Loganathan, Yang, Huanting, Wang, Xuyuan, Tan, Gaoyi, Liu, Guang, Zhao, Liya, Xia, Xuekui, Liu, Xiangyang, Gao, Shushan, Ma, Lei, Liu, Mei, Ren, Biao, Dai, Huanqin, Quinn, Ronald J., Hsiang, Tom, Zhang, Jingyu, Zhang, Lixin and Liu, Xueting (2021). Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi. Applied Microbiology and Biotechnology, 105 (13), 5407-5417. doi: 10.1007/s00253-021-11192-3

Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi

2021

Journal Article

Peculiarities of meroterpenoids and their bioproduction

Han, Jianying, Jiang, Lan, Zhang, Lixin, Quinn, Ronald J., Liu, Xueting and Feng, Yunjiang (2021). Peculiarities of meroterpenoids and their bioproduction. Applied Microbiology and Biotechnology, 105 (10), 3987-4003. doi: 10.1007/s00253-021-11312-z

Peculiarities of meroterpenoids and their bioproduction

2021

Journal Article

Antimicrobial benzyltetrahydroisoquinoline-derived alkaloids from the leaves of Doryphora aromatica

Liu, Miaomiao, Han, Jianying, Feng, Yunjiang, Guymer, Gordon, Forster, Paul and Quinn, Ronald J. (2021). Antimicrobial benzyltetrahydroisoquinoline-derived alkaloids from the leaves of Doryphora aromatica. Journal of Natural Products, 84 (3), 676-682. doi: 10.1021/acs.jnatprod.0c01093

Antimicrobial benzyltetrahydroisoquinoline-derived alkaloids from the leaves of Doryphora aromatica

2020

Journal Article

Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson's disease patient-derived cell line

Nguyen, Duy Thanh, Iqbal, Jamila, Han, Jianying, Pierens, Gregory K., Wood, Stephen A., Mellick, George D. and Feng, Yunjiang (2020). Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson's disease patient-derived cell line. Bioorganic and Medicinal Chemistry, 28 (21) 115732, 1-9. doi: 10.1016/j.bmc.2020.115732

Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson's disease patient-derived cell line

2020

Journal Article

Genome-inspired chemical exploration of marine fungus aspergillus fumigatus MF071

Han, Jianying, Liu, Miaomiao, Jenkins, Ian D., Liu, Xueting, Zhang, Lixin, Quinn, Ronald J. and Feng, Yunjiang (2020). Genome-inspired chemical exploration of marine fungus aspergillus fumigatus MF071. Marine Drugs, 18 (7) md18070353, 352. doi: 10.3390/md18070352

Genome-inspired chemical exploration of marine fungus aspergillus fumigatus MF071

2020

Journal Article

Discovery of a natural product that binds to the mycobacterium tuberculosis protein Rv1466 using native mass spectrometry

Elnaas, Ali R., Grice, Darren, Han, Jianying, Feng, Yunjiang, Capua, Angela Di, Mak, Tin, Laureanti, Joseph A., Buchko, Garry W., Myler, Peter J., Cook, Gregory, Quinn, Ronald J. and Liu, Miaomiao (2020). Discovery of a natural product that binds to the mycobacterium tuberculosis protein Rv1466 using native mass spectrometry. Molecules, 25 (10) 2384, 2384. doi: 10.3390/molecules25102384

Discovery of a natural product that binds to the mycobacterium tuberculosis protein Rv1466 using native mass spectrometry

2020

Journal Article

Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

Han, Jianying, Zhang, Jingyu, Song, Zhijun, Zhu, Guoliang, Liu, Miaomiao, Dai, Huanqin, Hsiang, Tom, Liu, Xueting, Zhang, Lixin, Quinn, Ronald J and Feng, Yunjiang (2020). Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134. Applied Microbiology and Biotechnology, 104 (9), 3835-3846. doi: 10.1007/s00253-020-10522-1

Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

2019

Journal Article

Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049

Zhang, Jingyu, Wang, Zhenzhen, Song, Zhijun, Karthik, Loganathan, Hou, Chengjian, Zhu, Guoliang, Jiang, Lan, Han, Jianying, Ma, Rong, Li, Li, Zhang, Lixin, Liu, Xueting and Hsiang, Tom (2019). Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049. Synthetic and Systems Biotechnology, 4 (4), 173-179. doi: 10.1016/j.synbio.2019.09.001

Brocaeloid D, a novel compound isolated from a wheat pathogenic fungus, Microdochium majus 99049

2019

Journal Article

Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

Han, Jianying, Zhang, Jingyu, Song, Zhijun, Liu, Miaomiao, Hu, Jiansen, Hou, Chengjian, Zhu, Guoliang, Jiang, Lan, Xia, Xuekui, Quinn, Ronald J., Feng, Yunjiang, Zhang, Lixin, Hsiang, Tom and Liu, Xueting (2019). Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134. Applied Microbiology and Biotechnology, 103 (13), 5167-5181. doi: 10.1007/s00253-019-09821-z

Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134

2017

Journal Article

A systems approach using OSMAC, Log P and NMR fingerprinting: an approach to novelty

Liu, Miaomiao, Grkovic, Tanja, Liu, Xueting, Han, Jianying, Zhang, Lixin and Quinn, Ronald J. (2017). A systems approach using OSMAC, Log P and NMR fingerprinting: an approach to novelty. Synthetic and Systems Biotechnology, 2 (4), 276-286. doi: 10.1016/j.synbio.2017.10.001

A systems approach using OSMAC, Log P and NMR fingerprinting: an approach to novelty

2016

Journal Article

Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity

He, Wenni, Liu, Miaomiao, Li, Xiaolin, Zhang, Xiaoping, Abdel-Mageed, Wael M., Li, Li, Wang, Wenzhao, Zhang, Jingyu, Han, Jianying, Dai, Huanqin, Quinn, Ronald J., Liu, Hung-wen, Luo, Houwei, Zhang, Lixin and Liu, Xueting (2016). Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity. Applied Microbiology and Biotechnology, 100 (19), 8349-8357. doi: 10.1007/s00253-016-7488-6

Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity

2016

Journal Article

Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation

He, Wenni, Liu, Miaomiao, Huang, Pei, Abdel-Mageed, Wael M., Han, Jianying, Watrous, Jeramie D., Nguyen, Don D., Wang, Wenzhao, Song, Fuhang, Dai, Huanqin, Zhang, Jingyu, Quinn, Ronald J., Grkovi, Tanja, Luo, Houwei, Zhang, Lixin and Liu, Xueting (2016). Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation. Synthetic and Systems Biotechnology, 1 (3), 187-194. doi: 10.1016/j.synbio.2016.05.002

Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation

2016

Journal Article

Anti-MRSA and anti-TB metabolites from marine-derived Verrucosispora sp MS100047

Huang, Pei, Xie, Feng, Ren, Biao, Wang, Qian, Wang, Jian, Wang, Qi, Abdel-Mageed, Wael M., Liu, Miaomiao, Han, Jianying, Oyeleye, Ayokunmi, Shen, Jinzhao, Song, Fuhang, Dai, Huanqin, Liu, Xueting and Zhang, Lixin (2016). Anti-MRSA and anti-TB metabolites from marine-derived Verrucosispora sp MS100047. Applied Microbiology and Biotechnology, 100 (17), 7437-7447. doi: 10.1007/s00253-016-7406-y

Anti-MRSA and anti-TB metabolites from marine-derived Verrucosispora sp MS100047