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2024

Journal Article

Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans

Hahn, Anne, Hung, Grace Ching Ching, Ahier, Arnaud, Dai, Chuan-Yang, Kirmes, Ina, Forde, Brian M., Campbell, Daniel, Lee, Rachel Shin Yie, Sucic, Josiah, Onraet, Tessa and Zuryn, Steven (2024). Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans. Cell Metabolism. doi: 10.1016/j.cmet.2024.07.020

Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans

2023

Journal Article

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription

Dai, Chuan-Yang, Ng, Chai Chee, Hung, Grace Ching Ching, Kirmes, Ina, Hughes, Laetitia A., Du, Yunguang, Brosnan, Christopher A., Ahier, Arnaud, Hahn, Anne, Haynes, Cole M., Rackham, Oliver, Filipovska, Aleksandra and Zuryn, Steven (2023). ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature Cell Biology, 25 (8), 1-10. doi: 10.1038/s41556-023-01192-y

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription

2020

Journal Article

DNA Methyltransferase 1 (DNMT1) function is implicated in the age-related loss of cortical interneurons

Hahn, Anne, Pensold, Daniel, Bayer, Cathrin, Tittelmeier, Jessica, Gonzalez-Bermudez, Lourdes, Marx-Bluemel, Lisa, Linde, Jenice, Gross, Jonas, Salinas-Riester, Gabriela, Lingner, Thomas, von Maltzahn, Julia, Spehr, Marc, Pieler, Tomas, Urbach, Anja and Zimmer-Bensch, Geraldine (2020). DNA Methyltransferase 1 (DNMT1) function is implicated in the age-related loss of cortical interneurons. Frontiers in Cell and Developmental Biology, 8 639, 1-19. doi: 10.3389/fcell.2020.00639

DNA Methyltransferase 1 (DNMT1) function is implicated in the age-related loss of cortical interneurons

2019

Journal Article

Mitochondrial genome (mtDNA) mutations that generate reactive oxygen species

Hahn, Anne and Zuryn, Steven (2019). Mitochondrial genome (mtDNA) mutations that generate reactive oxygen species. Antioxidants, 8 (9) 392, 392. doi: 10.3390/antiox8090392

Mitochondrial genome (mtDNA) mutations that generate reactive oxygen species

2018

Journal Article

The Cellular Mitochondrial Genome Landscape in Disease

Hahn, Anne and Zuryn, Steven (2018). The Cellular Mitochondrial Genome Landscape in Disease. Trends in Cell Biology, 29 (3), 227-240. doi: 10.1016/j.tcb.2018.11.004

The Cellular Mitochondrial Genome Landscape in Disease

2018

Journal Article

DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications

Symmank, Judit, Bayer, Cathrin, Schmidt, Christiane, Hahn, Anne, Pensold, Daniel and Zimmer-Bensch, Geraldine (2018). DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications. Epigenetics, 13 (5), 536-556. doi: 10.1080/15592294.2018.1475980

DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications

2017

Journal Article

The DNA Methyltransferase 1 (DNMT1) controls the shape and dynamics of migrating POA-derived interneurons fated for the murine cerebral cortex

Pensold, Daniel, Symmank, Judit, Hahn, Anne, Lingner, Thomas, Salinas-Riester, Gabriela, Downie, Bryan R., Ludewig, Fabian, Rotzsch, Anne, Haag, Natja, Andreas, Nico, Schubert, Katrin, Huebner, Christian A., Pieler, Tomas and Zimmer, Geraldine (2017). The DNA Methyltransferase 1 (DNMT1) controls the shape and dynamics of migrating POA-derived interneurons fated for the murine cerebral cortex. Cerebral Cortex, 27 (12), 5696-5714. doi: 10.1093/cercor/bhw341

The DNA Methyltransferase 1 (DNMT1) controls the shape and dynamics of migrating POA-derived interneurons fated for the murine cerebral cortex