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2023

Journal Article

Endocytosis in cancer and cancer therapy

Banushi, Blerida, Joseph, Shannon R., Lum, Benedict, Lee, Jason J. and Simpson, Fiona (2023). Endocytosis in cancer and cancer therapy. Nature Reviews Cancer, 23 (7), 1-24. doi: 10.1038/s41568-023-00574-6

Endocytosis in cancer and cancer therapy

2022

Journal Article

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

Tran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

2021

Journal Article

Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis

McInerney-Leo, Aideen M., Chew, Hui Yi, Inglis, Po-Ling, Leo, Paul J., Joseph, Shannon R., Cooper, Caroline L., Okano, Satomi, Hassall, Tim, Anderson, Lisa, Bowman, Rayleen V., Gattas, Michael, Harris, Jessica E., Marshall, Mhairi S., Shaw, Janet G., Wheeler, Lawrie, Yang, Ian A., Brown, Matthew A., Fong, Kwun M., Simpson, Fiona and Duncan, Emma L. (2021). Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis. Human Molecular Genetics, 30 (24), 2393-2401. doi: 10.1093/hmg/ddab172

Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis

2021

Journal Article

Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: a review

Karlsen, Emma-Anne, Kahler, Sam, Tefay, Joan, Joseph, Shannon R. and Simpson, Fiona (2021). Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: a review. Cells, 10 (5) 1206, 1206. doi: 10.3390/cells10051206

Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: a review

2020

Journal Article

Antibody/ligand-target receptor internalization assay protocol using fresh human or murine tumor ex vivo samples

Joseph, Shannon R., Lum, Benedict, Banushi, Blerida, Barry, Rachael, Panizza, Benedict, Walpole, Euan and Simpson, Fiona (2020). Antibody/ligand-target receptor internalization assay protocol using fresh human or murine tumor ex vivo samples. STAR Protocols, 1 (2) 100087, 100087. doi: 10.1016/j.xpro.2020.100087

Antibody/ligand-target receptor internalization assay protocol using fresh human or murine tumor ex vivo samples

2020

Journal Article

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

2020

Journal Article

Epidermal Growth Factor Receptor’s Function in Cutaneous Squamous Cell Carcinoma and Its Role as a Therapeutic Target in the Age of Immunotherapies

de Lima, Priscila Oliveira, Joseph, Shannon, Panizza, Benedict and Simpson, Fiona (2020). Epidermal Growth Factor Receptor’s Function in Cutaneous Squamous Cell Carcinoma and Its Role as a Therapeutic Target in the Age of Immunotherapies. Current Treatment Options in Oncology, 21 (1) 9, 9. doi: 10.1007/s11864-019-0697-3

Epidermal Growth Factor Receptor’s Function in Cutaneous Squamous Cell Carcinoma and Its Role as a Therapeutic Target in the Age of Immunotherapies

2018

Journal Article

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018). An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, 139 (1), 213-223. doi: 10.1016/j.jid.2018.06.190

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

2018

Journal Article

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

He, Xuzhi, Cruz, Jazmina L., Joseph, Shannon, Pett, Nicola, Chew, Hui Yi, Tuong, Zewen K., Okano, Satomi, Kelly, Gabrielle, Veitch, Margaret, Simpson, Fiona and Wells, James W. (2018). Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab. Oncotarget, 9 (15), 12250-12260. doi: 10.18632/oncotarget.24242

Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab

2015

Journal Article

Phenothiazine-derived antipsychotic drugs inhibit dynamin and vlathrin-mediated endocytosis

Daniel, James A., Chau, Ngoc, Abdel-Hamid, Mohammed K., Hu, Lingbo, von Kleist, Lisa, Whiting, Ainslie, Krishnan, Sai, Maamary, Peter, Joseph, Shannon R., Simpson, Fiona, Haucke, Volker, McCluskey, Adam and Robinson, Philip J. (2015). Phenothiazine-derived antipsychotic drugs inhibit dynamin and vlathrin-mediated endocytosis. Traffic, 16 (6), 635-654. doi: 10.1111/tra.12272

Phenothiazine-derived antipsychotic drugs inhibit dynamin and vlathrin-mediated endocytosis

2011

Journal Article

KIAA0101 (KIAA0101)

Joseph, Shannon, Hu, Lingbo and Simpson, Fiona (2011). KIAA0101 (KIAA0101). Atlas of Genetics and Cytogenetics in Oncology and Haematology

KIAA0101 (KIAA0101)

2008

Journal Article

Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis

Desclozeaux, Marion, Venturato, Juliana, Wylie, Fiona G., Kay, Jason G., Joseph, Shannon R., Le, Huong T. and Stow, Jennifer L. (2008). Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis. Americal Journal of Physiology: Cell Physiology, 295 (2), C545-C556. doi: 10.1152/ajpcell.00097.2008

Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis

2007

Journal Article

EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin

Bryant, D. M., Kerr, M. C., Hammond, L. A., Joseph, S. R., Mostov, K. E., Teasdale, R. D. and Stow, J. L. (2007). EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. Journal of Cell Science, 120 (10), 1818-1828. doi: 10.1242/jcs.000653

EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin

2003

Journal Article

The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion

Pagan, J. K., Wylie, F. G., Joseph, S. R., Widberg, C., Bryant, N. J., James, D. E. and Stow, J. L. (2003). The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion. Current Biology, 13 (2), 156-160. doi: 10.1016/S0960-9822(03)00006-X

The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion

2003

Journal Article

Contextual binding of p120ctn to E-cadherin at the basolateral plasma membrane in polarized epithelia

Miranda, K. C., Joseph, S. R., Yap, A. S., Teasdale, R. D. and Stow, J. L. (2003). Contextual binding of p120ctn to E-cadherin at the basolateral plasma membrane in polarized epithelia. Journal of Biological Chemistry, 278 (44), 43480-43488. doi: 10.1074/jbc.M305525200

Contextual binding of p120ctn to E-cadherin at the basolateral plasma membrane in polarized epithelia

2002

Journal Article

Protein kinase C regulates endocytosis and recycling of E-cadherin

Le, T. L., Joseph, S. R., Yap, A. S. and Stow, J. L. (2002). Protein kinase C regulates endocytosis and recycling of E-cadherin. American Journal of Physiology-cell Physiology, 283 (2), C489-C499. doi: 10.1152/ajpcell.00566.2001

Protein kinase C regulates endocytosis and recycling of E-cadherin