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Dr

Michael Healy

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Overview

Availability

Dr Michael Healy is:
Available for supervision

Qualifications

  • Doctor of Philosophy of Protein Trafficking, University of Queensland

Works

Search Professor Michael Healy’s works on UQ eSpace

13 works between 2017 and 2024

1 - 13 of 13 works

2024

Journal Article

Mechanism and regulation of cargo entry into the Commander endosomal recycling pathway

Butkovič, Rebeka, Walker, Alexander P., Healy, Michael D., McNally, Kerrie E., Liu, Meihan, Veenendaal, Tineke, Kato, Kohji, Liv, Nalan, Klumperman, Judith, Collins, Brett M. and Cullen, Peter J. (2024). Mechanism and regulation of cargo entry into the Commander endosomal recycling pathway. Nature Communications, 15 (1) 7180, 1-15. doi: 10.1038/s41467-024-50971-0

Mechanism and regulation of cargo entry into the Commander endosomal recycling pathway

2024

Journal Article

Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2

Weeratunga, Saroja, Gormal, Rachel S., Liu, Meihan, Eldershaw, Denaye, Livingstone, Emma K., Malapaka, Anusha, Wallis, Tristan P., Bademosi, Adekunle T., Jiang, Anmin, Healy, Michael D., Meunier, Frederic A. and Collins, Brett M. (2024). Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2. Journal of Biological Chemistry, 300 (1) 105541, 105541. doi: 10.1016/j.jbc.2023.105541

Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2

2023

Journal Article

The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking

Healy, Michael D. and Collins, Brett M. (2023). The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking. Biochemical Society Transactions, 51 (6), 2005-2016. doi: 10.1042/bst20220804

The PDLIM family of actin-associated proteins and their emerging role in membrane trafficking

2023

Journal Article

CRISPR-Cas9 direct fusions for improved genome editing via enhanced homologous recombination

Tabassum, Tahmina, Pietrogrande, Giovanni, Healy, Michael and Wolvetang, Ernst J. (2023). CRISPR-Cas9 direct fusions for improved genome editing via enhanced homologous recombination. International Journal of Molecular Sciences, 24 (19) 14701, 1-17. doi: 10.3390/ijms241914701

CRISPR-Cas9 direct fusions for improved genome editing via enhanced homologous recombination

2023

Conference Publication

Structure of the endosomal Commander complex mutated in Ritscher-Schinzel syndrome: combining crystallography, cryo-EM and AlphaFold2

Healy, Michael D., McNally, Kerrie E., Butkovic, Rebeka, Chilton, Molly, Kato, Kohji, Sacharz, Joanna, McConville, Calum, Moody, Edmund R. R., Shaw, Shrestha, Planelles-Herrero, Vicente J. and Sathish, K. N. (2023). Structure of the endosomal Commander complex mutated in Ritscher-Schinzel syndrome: combining crystallography, cryo-EM and AlphaFold2. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323090538

Structure of the endosomal Commander complex mutated in Ritscher-Schinzel syndrome: combining crystallography, cryo-EM and AlphaFold2

2023

Journal Article

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

Healy, Michael D., McNally, Kerrie E., Butkovič, Rebeka, Chilton, Molly, Kato, Kohji, Sacharz, Joanna, McConville, Calum, Moody, Edmund R. R., Shaw, Shrestha, Planelles-Herrero, Vicente J., Yadav, Sathish K. N., Ross, Jennifer, Borucu, Ufuk, Palmer, Catherine S., Chen, Kai-En, Croll, Tristan I., Hall, Ryan J., Caruana, Nikeisha J., Ghai, Rajesh, Nguyen, Thi H. D., Heesom, Kate J., Saitoh, Shinji, Berger, Imre, Schaffitzel, Christiane, Williams, Tom A., Stroud, David A., Derivery, Emmanuel, Collins, Brett M. and Cullen, Peter J. (2023). Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome. Cell, 186 (10), 2219-2237.e29. doi: 10.1016/j.cell.2023.04.003

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

2022

Journal Article

Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

Healy, Michael D., Sacharz, Joanna, McNally, Kerrie E., McConville, Calum, Tillu, Vikas A., Hall, Ryan J., Chilton, Molly, Cullen, Peter J., Mobli, Mehdi, Ghai, Rajesh, Stroud, David A. and Collins, Brett M. (2022). Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins. Structure, 30 (12), 1590-1602.e6. doi: 10.1016/j.str.2022.10.001

Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

2021

Journal Article

De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

Chen, Kai-En, Guo, Qian, Hill, Timothy A., Cui, Yi, Kendall, Amy K., Yang, Zhe, Hall, Ryan J., Healy, Michael D., Sacharz, Joanna, Norwood, Suzanne J., Fonseka, Sachini, Xie, Boyang, Reid, Robert C., Leneva, Natalya, Parton, Robert G., Ghai, Rajesh, Stroud, David A., Fairlie, David P, Suga, Hiroaki, Jackson, Lauren P., Teasdale, Rohan D., Passioura, Toby and Collins, Brett M. (2021). De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Science Advances, 7 (49) eabg4007, eabg4007. doi: 10.1126/sciadv.abg4007

De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

2021

Other Outputs

Structural and functional characterisation of the commander trafficking complex and accessory proteins

Healy, Michael (2021). Structural and functional characterisation of the commander trafficking complex and accessory proteins. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/4930e26

Structural and functional characterisation of the commander trafficking complex and accessory proteins

2019

Journal Article

Towards a molecular understanding of endosomal trafficking by Retromer and Retriever

Chen, Kai‐En, Healy, Michael D. and Collins, Brett M. (2019). Towards a molecular understanding of endosomal trafficking by Retromer and Retriever. Traffic, 20 (7) tra.12649, 465-478. doi: 10.1111/tra.12649

Towards a molecular understanding of endosomal trafficking by Retromer and Retriever

2019

Journal Article

Elucidating the lipid binding properties of membrane-active peptides using cyclised nanodiscs

Zhang, Alan H., Edwards, Ingrid A., Mishra, Biswa P., Sharma, Gagan, Healy, Michael D., Elliott, Alysha, Blaskovich, Mark A. T., Cooper, Matthew A., Collins, Brett M., Jia, Xinying and Mobli, Mehdi (2019). Elucidating the lipid binding properties of membrane-active peptides using cyclised nanodiscs. Frontiers in Chemistry, 7 (MAR) 238, 238. doi: 10.3389/fchem.2019.00238

Elucidating the lipid binding properties of membrane-active peptides using cyclised nanodiscs

2018

Journal Article

Structural insights into the architecture and membrane interactions of the conserved COMMD proteins

Healy, Michael D., Hospenthal, Manuela K., Hall, Ryan J., Chandra, Mintu, Chilton, Molly, Tillu, Vikas, Chen, Kai-En, Celligoi, Dion J., McDonald, Fiona J., Cullen, Peter J., Lott, J. Shaun, Collins, Brett M. and Ghai, Rajesh (2018). Structural insights into the architecture and membrane interactions of the conserved COMMD proteins. eLife, 7 e35898. doi: 10.7554/elife.35898

Structural insights into the architecture and membrane interactions of the conserved COMMD proteins

2017

Journal Article

Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor

Abraham, Nikita, Healy, Michael, Ragnarsson, Lotten, Brust, Andreas, Alewood, Paul F. and Lewis, Richard J. (2017). Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor. Scientific Reports, 7 (1) 45466, 45466. doi: 10.1038/srep45466

Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor

Funding

Past funding

  • 2023 - 2025
    Protein homeostasis in Alzheimer's disease: Molecular basis for APP trafficking by the SNX17-Commander protein complex
    Dementia Australia Research Foundation Project Grants
    Open grant

Supervision

Availability

Dr Michael Healy is:
Available for supervision

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Media

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